Mosquito-borne illnesses have killed two captive orcas at SeaWorld since they became water park attractions.

Read the 2012 study about captive orcas and the threat of mosquito-borne illness

Written by orca trainers who went on to become scientists, it states mosquitoes bite orcas at night when the animals hang out close to the surface. What's more, antibiotics used to keep captive orcas healthy also may depress their immune response, boosting the risks of them being unable to fight off diseases like West Nile Virus and encephalitis, which have killed orcas at US water parks.

Mosquitoes top the ranking of the world's deadliest animals.

Some mosquitoes are key pollinators—and eat disease-carrying mosquitoes.

In recent years, orcas have begun sinking boats and other orcas are following in their footsteps

For just over five years, killer whales have been ramming (and occasionally sinking) expensive yachts, sailboats, and fishing boats in waters near European coasts. Scientists believe these incidents are the result of play rather than aggressive attacks.

West Nile Virus has been detected in American alligators, and outbreaks have led to substantial economic losses on alligator farms.

Mosquitoes are the world's deadliest animal, but gene drives could kill them.

Vector-borne diseases kill more than 700,000 people globally each year—and are growing

The diseases with the greatest potential to spread widely aren't the ones that quickly kill human hosts. Instead, the best hosts or reservoirs for vector-borne diseases would be chronically ill over the long term, increasing the likelihood that the pathogen could be transmitted to others.

More than 20 mosquito-borne and tick-borne diseases are found in the US

Children, older adults, and people with compromised immune systems are at particular risk of poorer health outcomes from these diseases. But dog owners and outdoor enthusiasts are among those at particular risk of contracting these illnesses, which include Lyme disease, Zika, and the condition Alpha-gal Syndrome.

Increasing contact between humans and wild animals is driving zoonotic threats

Zoonotic diseases, which spread from animals to humans, present one of the most significant emerging threats worldwide. Scientists have identified around 200 viruses capable of infecting humans, and unfortunately, the number of such diseases are on the rise—at least 60% of all emerging infectious diseases are zoonotic in origin.

Scientists found that if cats ate infected rodents, they could get West Nile in lab experiments.

There's no cure for West Nile virus—and infection can leave patients with permanent symptoms.

What if we killed every mosquito on Earth?

Mosquitoes aren't just annoying, they're deadly. they're also responsible for an estimated 725,000 deaths worldwide, every year. Would it be so bad if we found a way to wipe them out completely? Real scientists have gamed out this hypothetical scenario, concluding it actually wouldn't be that bad. This five-minute video breaks down one way this could happen.

Watch how viruses like Ebola can spill over from animals to humans—and vice-versa.

US West Nile case numbers were up 40% in 2025 across the United States though theories vary to explain this surge.

Horses account for about 96% of known mammalian cases of West Nile virus infection beyond humans.

West Nile Virus is maintained in nature, even without human infections

Mosquitoes pick up the virus when they feed on birds, and then pass it to other birds with their bite, delivering it via virus-laden saliva. Hundreds of different North American bird species can harbor the virus—even if they don't all get sick from it.

See this diverse list of vector-borne diseases

Human illnesses caused by parasites, viruses, and bacteria, and transmitted by a living organism—often small, bloodsucking ones like mosquitoes, ticks, and sandflies—are known as vector-borne diseases. That carrier is called a vector. These diseases disproportionately affect the poorest populations in tropical and subtropical areas.

Horses can—rarely—get West Nile, too

The animals can contract the virus via infected mosquito bites, but for horses there are four vaccines available. Though West Nile's often asymptomatic or mild in horses, the disease can sometimes be deadly, killing via severe neurological inflammation. There are no reported instances of people becoming sickened by infected horses or vice-versa.

Using mosquitoes to vaccinate bats could curb the spread of deadly diseases.

From 1970 to 2017, invasive species have caused $1.28T in damage globally

The costliest species were the Asian tiger and yellow fever mosquitoes ($149B), which arrived in the US from Asia and sub-Saharan Africa, respectively. The bulk of their damage came from their transmission of diseases such as Zika, chikungunya, and dengue. (Some readers may experience a paywall.)

Mosquitoes drink a maximum of 0.01 milliliters of blood in a single meal.

Nearly 5,500 crows died during four months in 1999 from West Nile in NYC.

How Disney World keeps out mosquitos

Disney World may have been built on a swamp, but it's nearly free from the annoyance of mosquitos. That hasn't been an easy task; Disney has worked with engineers and pest specialists on minimizing the invasive bugs through a variety of different methods. This Reader's Digest article breaks down how they've successfully kept the park free from these unwanted guests.

Wolbachia: the bacteria that could eliminate dengue fever

Dengue fever, transmitted by mosquitoes, kills more people annually than all types of natural disasters combined. However, mosquitoes that host Wolbachia bacterium have their ability to transmit the virus naturally suppressed, offering a route to eliminating nearly 25,000 deaths annually.

How a scientist discovered West Nile is spread by birds

Listen to Tracey McNamara, former chief pathologist at the Bronx Zoo, detailing her surprising late 1990s discovery that established West Nile virus is spread by birds. Financing animal disease surveillance studies, she says, saves human lives and surveillance gaps may fuel missed opportunities to identify dangerous diseases before they jump between species.

Long-term memory issues among West Nile survivors may be from the body's immune response, not the viral infection.

Explore inside a mosquito factory where millions of mosquitoes are bred weekly

In Medellin, Colombia, scientists are infecting Aedes aegypti mosquitoes with Wolbachia, a bacterium that wouldn't otherwise infect the species, but does block its ability to transmit dengue, Zika, yellow fever, and chikungunya. In the wild, infected mosquitoes would breed with wild mosquitoes, pass down Wolbachia, and thus reduce disease transmission.

California condors have been vaccinated against West Nile to protect their limited population

The condors became endangered in the 20th century primarily due to lead poisoning from consuming animals shot with lead bullet fragments inside them, so condors in captivity and in the wild are vaccinated against diseases including highly pathogenic avian flu and West Nile.

Zika virus shocked scientists because the mosquito-borne disease causes birth defects

This revelation, confirmed in 2016, marked the first time that a mosquito-borne disease was known to cause birth defects. Fetuses exposed to the Zika virus during pregnancy sometimes suffer from neurological complications and microcephaly, a small-headed condition associated with neurological development issues and impairment.

'Sloth fever' is an emerging health threat, especially to pregnant women

This disease, caused by the Oropouche virus, is found in animals including sloths, primates, and birds. It primarily spreads through the bite of midges—insects commonly called "no-see-ums." It's endemic to the Amazon region, but US travelers are increasingly contracting it internationally.

Invasive species can harm infrastructure and threaten human health

The wildfires in Hawaii in 2022 were made worse by flammable invasive grasses introduced from Africa as livestock pasture, and Zebra mussels native to the Caspian and Black Seas have spread across Europe and the US, where they can clog power plant pipes. Invasive mosquitoes can carry diseases, such as dengue and malaria.

West Nile virus was detected in UK mosquitoes for the first time in 2023

Fragments of the virus were detected in mosquitoes that were being collected in Britain for the first time in 2023, but the UK government considers the overall risk to people to be low. As of spring 2026, there have never been detected locally-acquired cases of the disease.

Dead birds are often the warning sign health officials look for as a sign of West Nile danger.

Iceland, the last mosquito-free country, detected them in 2025.

Supertoxic rat poisons are wreaking havoc on unintended targets, including predator birds, mammals, amphibians, crustaceans, and insects.

How we helped make Aedes aegypti mosquitoes such a problem

Mosquito genome sequencing data suggests that Aedes aegypti mosquitoes first started specializing on human blood around 5,000 years ago—when climates shifted and humans started domesticating plants in Africa and stored large amounts of water that may have attracted the bugs.

West Nile was reported in 47 states in 2025, with more than 1,400 people severely affected

Tracking numbers from the CDC indicate that the virus spread widely that year, with more than 2,000 reported human cases and many states seeing more than 25 sickened people. More than 1,400 people had neuroinvasive cases of the disease—meaning the virus had entered the nervous system, which can cause severe, potentially life-threatening illness.

10 locally acquired malaria cases were reported in the US in 2023—a surprise

The cases, reported in Florida, Texas, Maryland, and Arkansas, broke a 20-year streak since there had been no reported locally acquired mosquito-transmitted malaria in the country since 2003, when there was a case in Florida.

Most cases of West Nile virus are asymptomatic in people

About 1 in 5 infected people develop symptoms from West Nile, including symptoms such as fatigue, head and body aches, and vomiting. But around 1% of patients develop severe complications such as encephalitis or meningitis, which can be life-threatening. Those who are most likely to become severely ill are people over age 60.

Zoonotic diseases: Pathogens that jump from animals to humans

Such diseases may be caused by a variety of pathogens—viruses, bacteria, fungi, or parasites—and can originate in creatures ranging from ticks and mosquitoes to pigs and bats. Because they develop in animals and are often new to human immune systems, zoonotic diseases have severe consequences for public health.

Powassan virus, a rare tick-borne disease named after the Canadian town where it was discovered in 1958, is on the rise in the northeastern United States, and it kills roughly 10% to 15% of patients with symptomatic disease.

Wolbachia is also being used to slash mosquito numbers

The naturally occurring bacterium does not naturally infect Aedes aegypti mosquitoes, but communities in locations including California and Texas have released male mosquitoes infected with Wolbachia and reported a significant drop in subsequent mosquitoes: When infected males mate with uninfected wild females, the eggs don't hatch.

Hear what it's like to have malaria from a patient who suffered from the mosquito-borne disease.

Rabies kills more than 50,000 worldwide each year

Rabies transmission to humans typically comes from an infected animal, and death was very common before recent protocols were developed (post-exposure prophylaxis). The virus is neurotropic, which means it has an affinity for nerve tissue, and moves quickly from broadly infecting the body to destroying the brain.

West Nile virus found in the UK for the first time

The West Nile virus, which mainly spreads between birds and mosquitoes, was detected in the UK for the first time. While no evidence exists for any human infections, climate change may be expanding mosquitoes—and the diseases they carry—farther north.

A malaria case in Maryland stumped doctors in 2023—leading to the wrong treatment and underscoring the challenge of physicians being mindful of tropical diseases in our interconnected world.

Chimpanzees are dying from human colds

For some great apes, the threat of human-borne diseases outweighs poaching or habitat loss. This article details the danger of reverse zoonoses, which refers to diseases that spread from humans to animals.

Anopheles mosquitoes are developing resistance to insecticides.

We can get food poisoning from spending time in swimming pools, lakes, rivers, and ponds

Some of the same pathogens that may sicken us in food or water may also sicken us in recreational swimming environments. Bacteria can rub off of people’s (or animal’s) bodies or contaminate the water through a diarrheal episode. Washing your hands for at least 20 seconds before eating food if you are at the beach, pool, or other similar environments and being sure not to swallow the water are ways to help keep safe.

What are zoonotic diseases?

Interspecies interactions are a breeding ground for disease transmission. This basic background information on zoonotic disease from the Centers for Disease Control and Prevention (CDC) chronicles the different ways humans can get sick, identifies what groups are particularly vulnerable, and offers links to other resources.