Learn the history and science of influenza in 'This Podcast Will Kill You'

Explore the history of antibiotics with 'This Podcast Will Kill You'

The show blends medical history with storytelling and science. In Episode 50, the hosts trace the dramatic origins of antibiotics—from Fleming's moldy petri dish to Florey's wartime labs—and explore their lasting impact on health.

Hear firsthand stories from Americans who lived through the 1918 flu pandemic

This video shares personal accounts from survivors of the 1918 influenza epidemic, capturing memories of sickness, loss, and resilience. Their voices offer a glimpse into how ordinary people experienced one of history’s deadliest pandemics.

The flu is a contagious respiratory illness caused by influenza viruses

Unlike the common cold, influenza attacks suddenly with fever, body aches, and fatigue. Seasonal strains circulate worldwide, infecting up to a billion people each year and causing hundreds of thousands of deaths despite vaccines and treatments.

Human records of influenza stretch back more than two millennia

Accounts of flu-like illness appear as early as 412 BCE, when Hippocrates described a sudden wave of cough and fever. Centuries of recurring outbreaks culminated in the first clearly documented pandemic in 1580, spreading from Asia into Europe and Africa.

Human records of influenza stretch back more than two millennia

Accounts of flu-like illness appear as early as 412 BCE, when Hippocrates described a sudden wave of cough and fever. Centuries of recurring outbreaks culminated in the first clearly documented pandemic in 1580, spreading from Asia into Europe and Africa.

How the 1918 pandemic spurred developments in virology and vaccines

This article provides an in-depth historical account of the 1918 Spanish Flu pandemic, including its impact on the global population and how its occurrence spurred significant advancements in the study of viruses—laying the groundwork for the...

Small genetic changes that accumulate over time force flu vaccines to be updated regularly.

Explore a 3D model of the influenza virus

This interactive 3D model reveals the influenza virus’s structure—its outer coat and spike proteins—and compares it with other well-known viruses, offering a clear view of how flu differs from pathogens like HIV or coronaviruses.

The flu vaccine has evolved alongside discoveries of new virus strains

After influenza B was identified in 1940, researchers created a two-strain vaccine by 1942. The WHO later built a global surveillance system to track mutations, enabling vaccines to be updated annually to target the strains most likely to circulate.

Europe’s first recorded influenza pandemic swept the continent in 1580

The 1580 influenza pandemic, traced from Asia to Africa and into Europe, became the first flu outbreak clearly documented across the continent—killing tens of thousands and highlighting influenza’s potential for rapid global spread.

Flu spreads through droplets in the air and on surfaces

Influenza passes mainly through tiny droplets released when sick people cough, sneeze or talk. The virus can also survive briefly on surfaces, allowing it to spread when others touch contaminated objects.

Scientists from the frontline discuss the future of antibiotics and superbugs

Superbugs are a very real problem, but researchers around the world are working to advance our understanding of these pathogens and develop new medicines. This podcast talks with several scientists on the frontier of superbug research, offering insight into what we know—and what the future of medicine may look like.

In 1933, the influenza virus was first identified through 'ferret flu' experiments, which proved that the disease was viral—not bacterial.

Influenza infects up to a billion people worldwide each year

The World Health Organization estimates that seasonal influenza causes about 1B cases annually, including 3 to 5M severe illnesses and between 290,000 to 650,000 deaths.

COVID-19 vaccine breakthroughs are driving efforts toward a universal flu shot

mRNA and other technologies used for COVID-19 vaccines are being applied to influenza research. Scientists hope these advances will lead to a universal flu vaccine that protects against multiple strains and reduces the need for yearly shots.

The science of fear

The Hidden Brain podcast team explores the science of fear by traveling to a haunted house curated by a scientist to investigate what scares us, and why some people enjoy this sensation more than others.

Annual flu shots remain the best defense against influenza

Flu vaccination typically reduces the risk of medical visits by 30 to 60% and lowers hospitalization rates by around 40%. Between 2023 and 2024, in the US alone, vaccines prevented an estimated 120,000 hospitalizations and nearly 7,900 deaths.

Find out how prevalent the flu is at this current moment

Updated weekly, this USAFacts resource shares current data from the CDC detailing how many cases of influenza and other flu-like illnesses accounted for doctor's visits. Monitor the spread of respiratory illness during flu season with this handy resource and prepare accordingly.

Understanding insulin

Scientists Daniel and Kelly talk with researcher Dr. Katrine Whiteson about diabetes, the history of insulin production, and Dr. Lydia Villa-Komaroff—an essential member of the team who discovered that bacteria could be induced to produce insulin. Listen to discover interesting facts about the life-saving medicine and how it works in the human body.

True crime, explained

Tales exploring some of the most grisly and unthinkable crimes have satisfied the public's morbid curiosity for more than a century, and modern podcasting has shot the genre to new heights. Want to learn more about the history of true crime? 1440 has the breakdown here.

The 1957 and 1968 influenza pandemics caused millions of deaths worldwide

The 1957 H2N2 pandemic spread from East Asia, killing more than 1M globally, while the 1968 H3N2 pandemic began in Hong Kong and caused a similar toll, with both strains rapidly moving across continents.

A professor explains how podcasts built on radio's strengths

When podcasts were first produced in the early 2000s, they were often recordings of radio shows aimed at listeners who wanted to listen outside of the broadcast windows. Siobhan McHugh, an associate professor of journalism at Australia's University of Wollongong, argues that the form is built on radio's intimacy, amplifying the connection listeners feel with their favorite hosts.

Explore a podcast devoted to uncovering different conspiracy theories

Hear stories of controversial events from all around the world and come to your own conclusions about why they happened—and if someone shaped the narrative around them. From art fraud to the death of a Roman emperor, this Spotify podcast covers it all.

Hear from a NYC public health official who led the first US investigation into West Nile about the challenges investigators faced and their working theories about that outbreak.

How a deadly antarctic expedition turned poisonous

A deadly 1912 scientific expedition to the Antarctic took a turn for the worse when the expedition team's leader turned to man's best friend to fuel their journey. This 21-minute podcast episode provides a glimpse into the real-life dangers of...

Tracing the history of refrigeration

Refrigeration has become critical to most of our lives. But not long ago, it wasn't available. How did we become so dependent on our fridges and freezers? This fun, informative podcast traces the history of keeping it cool with ice and...

Major genetic shifts in flu viruses can spark global pandemics

Antigenic shift happens when two different influenza viruses infect the same host and swap genetic material. The result is a brand-new subtype of influenza which, if easily spread among people, can trigger a worldwide pandemic.

The dramatic story of the spies and scientists behind the atomic bomb

This podcast traces the dramatic origins of nuclear weapons—from the scientists racing to beat the Nazis in Season 1 to the Soviet spy who stole atomic secrets in Season 2.

How do vaccines work? Watch this brief 101

Watch this under-3-minute video explaining how vaccines use the body's immune system to prepare our bodies against viral and bacterial threats to our health.

Most flu vaccines are still produced using chicken eggs

For decades, influenza vaccines have been made by growing viruses inside fertilized chicken eggs. Though newer methods using cell cultures or recombinant technology exist, egg-based production remains the primary global manufacturing process.

A timeline of major pandemics from 1899–2025

Modern pandemics have been defined by the race between globalization (which increases risk) and the development of new medicines. The Great Influenza epidemic claimed some 50 million lives, and the COVID-19 pandemic killed more than 7 million. In between, diseases like Ebola, cholera, AIDS, and more have devastated communities.

Why the 1918 flu killed between 50 and 100 million people

The 1918–1920 flu pandemic (once called, incorrectly, the Spanish flu) killed quickly and in huge numbers, with estimates of the global death toll ranging from 50 to 100 million people. Several factors contributed to the high mortality rate: lack of antibiotics, the global disruption of World War I, and more.

The science of dogs, from wolf origins to color-blindness

This under 10-minute podcast episode dives into the rich, fascinating science behind dogs: From their world-class sense of smell to their domestication from wolves.

A riveting retelling of the 1846 Donner Party, the doomed western pioneers

Eighty-one people went with the Donner Party into the Sierra Nevada mountains in the winter of 1846 via what they thought would be a shortcut to the West. Only 41 came out. The infamous episode of Western travel is captured in narrative detail in this four-part podcast series. This first episode reveals the motivations that pushed the party on this specific route.

Flu viruses use special proteins to invade and spread in the body

Influenza viruses carry two key surface proteins: hemagglutinin (H), which lets them enter cells, and neuraminidase (N), which helps them escape and spread. These proteins are the basis for the names of flu subtypes like H1N1 and H3N2

A four-part podcast traces how the Manhattan Project reshaped the world

This podcast series explores the origins of the Manhattan Project, its secret cities, and the scientists behind it—showing how the effort contributed to the end of World War II, launched the Atomic Age, and later led Oppenheimer to become a critic of nuclear weapons.

The basics behind mRNA vaccines

In this video, Yale experts Saad Omer, MBBS, MPH, PhD; Onyema Ogbuagu, MBBCh; and Akiko Iwasaki, PhD, explain the science behind COVID-19 mRNA vaccines.

The secret lives of cells

Cutting-edge microscopy has revealed previously unseen interactions of biological molecules within their cellular environment, enabling scientists to observe and analyze the molecules in a holistic view. This podcast explains the minute advancements made over the last few decades in observing cells, revealing how scientists have come and what the future holds for the field.

Bird Flu is spreading—what does that mean for us and other species?

The rapid global spread of H5N1 bird flu—from remote Antarctic islands to US farms—shows how animal spillover, driven by human activity and ecological disruption, is accelerating pandemic risk across species long before sustained human transmission begins.

'Christmas Past' examines the forgotten stories behind holiday traditions

“Christmas Past” is a long-running podcast that explores the origins of Christmas traditions through short and engaging episodes, blending historical deep dives with warm-hearted narration.

Infertility is often not discussed, forcing women and families to grieve privately

Watch this podcast discussion from Weill Cornell Medicine about the emotional journey of infertility for couples and individuals and hear advice about how to navigate the feelings of loss of control, grief, anger, and despair, including suggested tips for supporting individuals struggling with infertility.

Ghost hunting in the 19th century

This 40-minute podcast explores what it meant to hunt ghosts during the 19th century, when studying the paranormal was considered a mainstream scientific field. In 1847, a pair of sisters reportedly communicated with the spirit of a dead man...

'Serial': The podcast that revived a genre (4 seasons)

"Serial" debuted in 2014, sparking the contemporary fascination with true crime podcast content with a look at the murder of teenager Hae Minh Lee in 1999, and the jailing of Adnan Syed. The Peabody Award-winning season became a pop culture sensation, spawned countless imitators, and was followed by three more seasons on new topics. Listen to all four seasons here.

Most flu cases are treated at home, but antivirals help high-risk patients

Rest, fluids and common medicines usually ease influenza symptoms. For people at higher risk of complications, doctors may prescribe antiviral drugs, which work best when started soon after symptoms begin.

Learn about the long and contested history of free speech in America

This podcast examines how American free speech protections evolved—from the Founders' debates to landmark Supreme Court rulings—and why the country arrived at one of the most expansive speech regimes in the world.

This is what happens inside your body when you're sick

This video details the biology of what happens inside the human body during illness.

A novel H1N1 influenza strain sparked a 2009 global pandemic

First detected in Mexico, the 2009 “swine flu” pandemic infected up to 1.4B people worldwide. While mortality rates were lower than earlier pandemics, the outbreak still caused more than 150,000 deaths.

Explore a technical look at the measles virus and its toll on humanity through the ages.

Airbnb started as a vacation rental startup and soon disrupted the hospitality industry

In this podcast episode, Airbnb gets the "How I Built This" treatment. The "How I Built This" host speaks with the entrepreneurs behind today's largest businesses about how they got started. In this episode, Airbnb's cofounder Joe Gebbia talks about how he built Airbnb.

Listen to a widely lauded historical fiction podcast about the manhunt and power struggle that gripped the US after President Abraham Lincoln's assassination.