Observant Catholics can donate organs because the official Catholic stance is brain death is death—enabling organ donation

Brain death is a top source of organ donation

Brain death is a significant source of organ donations because patients declared brain dead and hooked up to intensive care unit machines will still have oxygen flowing to organs like the heart, lungs, and kidneys—preserving those organs.

Brain death is a top source of organ donation

Brain death is a significant source of organ donations—approximately 40% of organs in the US and the UK are recovered from people who experience brain death. Patients declared brain dead and hooked up to intensive care unit machines will still have oxygen flowing to organs like the heart, lungs, and kidneys—preserving those organs.

Brain death is a medical diagnosis without any wiggle room

Seeking to resolve long-standing variations between hospitals and state procedures, in 2023 several expert groups published comprehensive step-by-step guidance for clinicians to follow when determining brain death in kids and adults. Among other guidelines, it stated that doctors don't need to get family consent to do the tests needed to make this determination.

'Donation after circulatory death' is on the rise

This occurs when a patient in a coma is on life support and family members agree to donate the organs. Watch this video about a 2025 New York Times investigation that identified 12 instances across nine states of bungled or premature attempts to retrieve organs from people whose families had authorized withdrawal of life support.

Brain death is a uniquely modern problem stemming from modern ventilators.

Brain death is very rare—only 2% of hospital patients have brain death in the US

A peer-reviewed analysis examining US hospital billing code data from 2012 to 2016 concluded that the incidence of brain death is about 2% in the country. There was no available information indicating what proportion of those patients underwent organ donation.

Organ donation isn't usually logistically possible if you die at home

Since organs need to be well-preserved for organ donation, with oxygen flowing through the body, internal organs often aren't viable for organ donation if someone dies at home. But some tissues—like eye corneas and skin tissue—may still be donated since they remain usable for a longer period without oxygen flow.

Research advances suggest death takes much longer than we realized

Recent research indicates that organs, including the brain, are better at handling a lack of oxygen after the heart stops beating than previously known. Such findings may open up possibilities that include someday reversing certain death processes and expanding the availability of organs available for organ donations. (Some users may experience a paywall.)

In 1968, a Harvard Medical School committee issued the first neurological definition of death

The definition set a legal and medical precedent for how we define death, important for issues including organ donation. This 2020 video podcast discusses the history of brain death controversies and the variability in how death has been determined, including discussions in the late 1960s about when patients are considered dead in the context of organ donations.

Watch this 2021 video demonstrating a full brain death examination

This video and accompanying article in the peer-reviewed New England Journal of Medicine show the then-standard steps of a full brain death examination—demonstrating the process on a medical dummy to search for pain, blinking, eye movement, cough, gagging, or other forms of responsiveness. (May need to sign up for a free account to view.)

Brain activity sometimes goes into overdrive around the point of death according to researchers' recent analysis of patients' brains before and after they were taken off their ventilators.

You can sign up to donate your organs at this website

A single person who chooses to donate their organs upon death can provide organs for as many as eight people. You can sign up to become an organ donor or update your donation status information at this website, or you can typically sign up at your state's Department of Motor Vehicles. Many states allow individuals to declare which tissues and organs you consent to donate (i.e. organs, eyes, and skin tissue). It's recommended to discuss your decision with your family so they are aware of your wishes.

In the US, you must actively sign up to donate your organs

The US has an opt-in donation system for organ donation—meaning people must provide consent to proceed with any donation. Locations including Spain, the United Kingdom, and Argentina have an opt-out donation system, which means individuals are presumed to be donors unless they actively refuse consent.

You can sign up to donate your body to science

It's a separate process to donate your body for medical research; you usually must contact a whole-body donation program directly. Bodies can be donated for medical research, for forensic analysis research, or for medical students to work with as they learn anatomy and surgery, among other purposes. Learn more about numerous accredited organizations that provide human bodies, organs, and tissues to medical researchers and students.

Scientists are studying dying patients' brain activity in the final moments of life

In the final moments of life there are distinctive bursts of coordinated neural activity. Researchers are interested in parsing that data to better understand the dying process and also exploring how this data relates to our understanding of consciousness.

Four in 10 CPR patients report consciousness not captured by standard measures.

Artificial intelligence may improve organ donation systems—and even organ health

Mayo Clinic transplant experts suggest that artificial intelligence could potentially improve organ donation systems in several ways, including better identifying patients most at risk for organ rejection, enhancing donor-recipient matching, and helping to avoid organ transplant needs by identifying health issues earlier.

Living donations most commonly involve a kidney or part of a liver

In 2023, more than 6,900 transplants were made possible thanks to living donors. Living donation is when a living person donates an organ or part of an organ—usually one of their two kidneys or part of the liver, since that organ can regenerate in a healthy person. Much more rarely, living donors donate other organs. Living donations often occur when someone wants to ensure a loved one has certainty that they will quickly receive a needed organ.

England changed to an organ donation opt-out system in May 2020

A law that went into effect in May 2020 in England changed the country's organ donation regulations, reflecting public support for organ donation. Now, adults are typically presumed to have agreed to donate their own organs upon death unless they declare they're refusing to donate organs (or their family opts them out).

What happens in a dying brain?

Near-death experiences usually happen during death or on the border of life and death when a person isn't understood to be conscious. This article details the science of what's going on with the brain during NDEs.

Several years after the English law changed, organ donation rates haven't improved

A 2024 analysis found that several years after England changed its organ donation system to an opt-out donation system there was no improvement to the country's organ donation rates, perhaps highlighting the need for better understanding and education around the law.

A 13-year-old was declared brain-dead yet went through puberty on a ventilator

This podcast details Jahi McMath's highly controversial case. She was declared brain-dead in 2013 following surgical complications, but her family, citing religious beliefs, kept her connected to a ventilator for the five years that followed. She continued to grow and went through puberty before being issued a second death certificate in New Jersey.

Pig brain cellular activity was restarted hours after death in study published in 2019

Yale University scientists restored basic cellular activity and circulatory function in pig brains about four hours after death with a synthetic cocktail of preservatives and nutrients. This work— which didn't restart electricity activity in the brain or consciousness—could help advance future human stroke and brain injury treatments.

Donated hearts remain viable three times longer now with new tech

Advances in organ perfusion systems have significantly lengthened the amount of time donated hearts can remain viable for transplant, expanding the possibilities for donor organs to wider geographic areas. "Heart in a box" devices, developed in recent years, enable effective oxygen flow in the donor heart during transport, which means that hearts can now travel farther to potential recipients and still be in good condition.

The body's response to cardiac arrest has been linked to near-death experiences.

There's a new (contested) physiological explanation for near-death experiences based on analysis of the brains of resuscitated coma and cardiac arrest patients.

When is someone actually dead?

Death is a process, not a sudden flip of a switch. Technology can now interrupt this process at various stages, begging the question of when exactly death happens in the dying process. This 33-minute podcast episode explores this question and the...

UNOS oversees the entire US organ donation system

The United Network for Organ Sharing is a private, nonprofit organization that manages much of the US organ donation and transplantation system under a federal contract. Medical urgency, blood type, organ size, and geography of the donor and recipient are all factors determining how someone who needs an organ is matched with someone who donated an organ.

Transplanted organs can be rejected by the body immediately, months after transplant, or slowly over years

Organ rejection remains a huge challenge for organ transplant recipients. Rejection occurs when a recipient's immune system identifies a transplanted organ as foreign and attacks it. Recipient-donor screening processes try to match antigens to help reduce this risk.

Some scientists argue NDEs are constructed by the brain, not actually experienced

Despite the powerful memories associated with NDEs, scientists question the idea that the experiences prove consciousness endures after death, opting instead to find physiological explanations for common reports of out-of-body experiences, euphoric and lucid thinking, and more.

Meet the Dutch cardiologist who believes consciousness can exist outside the body

Dutch cardiologist Dr. Pim van Lommel conducted one of the largest studies of near-death experiences following cardiac arrest, publishing the results in the prestigous journel The Lancet. He later went on to argue (to significant criticism from peers) that his findings suggest consciousness can exist outside the body.

More than 40 states have passed versions of the Uniform Declaration of Death Act

The 1981 model law, now enacted in most states, is the legal basis for death in the US. There have been many efforts to amend this law, citing the need for more transparency to improve trust between families and the medical profession, though none have moved forward. Alterations to the law could have implications for organ donations and removing life support.

Open brain surgery is not required for BCIs inserted via blood vessel injection

Synchron's brain-computer interface, the Synchron Switch, takes advantage of preexisting medical devices, such as stents and catheters. Cells grow over the device over a 90-day period, incorporating it into the vessel wall and minimizing clots.

'Human composting' is an eco-friendly burial method legal in only a few states

Formally known as natural human organ reduction, this process relies on the same principles as standard composting and breaks down the body over many weeks, turning it into a type of soil. It's currently only legal in a handful of states.

In 1984, a dying infant lived for three weeks with a baboon heart inside her chest.

The human body relaxes upon death, including the bowel and bladder, expelling urine and feces

Watch a hospice nurse walk through how death affects the human body and what to expect in the hours and days following the death of a loved one as the body breaks down.

Pig organ transplants are apparently kosher—you just can’t eat them

Science writer Mary Roach speaks with journalist Terry Gross about her latest book, “Replaceable You: Adventures in Human Anatomy” and discusses topics including why pig organs have become of such interest and what religious leaders have told her about pig organs and compliance with Jewish dietary law.

Some medical schools have phased out human cadavers for digital alternatives

AI-based anatomy tools and digital cadavers are increasingly used to teach students, bypassing the ethical and consent concerns around the use of real bodies. Digital cadavers have also become less expensive than real ones, though the tactile and sensory experiences of real dissection may be irreplaceable.

Xenotransplants are an experimental last resort for the terminally ill when they cannot or will not receive a human organ.

Research suggests the brain maintains connections to lost limbs

Decades-old research suggested brain reorganization after amputations, but brain scans show unchanged limb representations. Phantom limb pain may result from such unchanged brain maps, which may enhance prosthetic limb control in brain-computer interface technology.

Chinese scientists transplanted a pig lung into a human being in 2025—but it had to be removed.

Which organs can you live without?

While there are some organs (such as the heart) that people simply can’t live without, there are other organs that can be removed without a huge impact. Patients who have their appendix removed, for example, experience no changes to their daily...

The Lazarus Effect is when a heart begins beating on its own after declared death

Formally called autoresuscitation, this rare phenomenon occurs when someone is declared dead following a cardiac arrest but their heart beats again without help—making it seem like the person came back to life. Doctors don't know the exact cause.

A radiation oncologist has studied near-death experience reports for over 25 years and compiled around 4,000 accounts in the hopes of finding more patterns that would reveal insights about consciousness and humans' final moments before or around death.

Near-death experiences can be reminiscent of religious visions, yet people across different faiths as well as those with no declared religion have reported them.

Neural interfaces offer major medical potential but raise serious ethical concerns

Although brain-computer interfaces can help people recover lost functions and allow direct brain-to-computer communication in the future, surveys have shown little public support for using them to boost abilities like memory or focus in healthy people.

Mummification involves drying a body to preserve it long-term

It was a common and respected practice in many ancient societies. The Egyptians perfected the ritual as part of their religious views of death, believing the dead needed to remain physically intact to reach the afterlife. Mummies were common also in ancient China, Mesoamerica, and the Canary Islands.

This Indiana medical school encouraged students to get to know their cadavers' families

The school's anatomy professor instructed medical students to think of the cadavers they worked with as their "first patients"—using their names to acknowledge that this was a person and to exchange letters with the cadaver's family members if they agreed to participate. At the conclusion of the course, families were invited to a lab-based memorial service.

Medical recognition of strokes stretches back to ancient Greece

Every minute, 750 milliliters of blood flows to the brain, supplying 20% of the body’s oxygen. A sudden disruption—whether from a clot (ischemic stroke) or a bleed (hemorrhagic stroke)—can be life-threatening. From ancient Greek theories to modern CT and MRI scans, here’s how stroke science has evolved over time.

Scientists may have discovered why gene-edited pig kidneys are rejected in humans

In November 2025, researchers studying how a brain-dead donor’s body responded to the transplantation of a genetically engineered pig kidney, published that they’ve identified immune system reactions that may explain why these pig organs get rejected. What’s more, they were able to reverse the rejections with an already available drug combination and the kidney functioned well. They also pinpointed a way to detect a potential rejection up to five days sooner.