Antimalarials must be taken before traveling to a malaria-endemic area

Anopheles mosquitoes are developing resistance to insecticides.

Hear what it's like to have malaria from a patient who suffered from the mosquito-borne disease.

See this graphic of the complex malaria transmission lifecycle.

Protecting yourself from West Nile involves avoiding getting bites and clearing standing water.

Female Anopheles mosquito bites are the primary way malaria spreads.

Malaria vaccines are not routine because they have limited effectiveness.

Untreated malaria can lead to blocked blood vessels in the brain, coma, and organ failure.

There are two recommended malaria vaccines by world health experts, but both have limited effectiveness.

Malaria comes from the Italian term 'mal'aria,' meaning 'bad air'

The term refers to marshy areas associated with the disease. An estimated 94% of malaria cases—215 million—occur in Africa.

The most severe form of malaria is caused by the Plasmodium falciparum parasite.

A malaria case in Maryland stumped doctors in 2023—leading to the wrong treatment and underscoring the challenge of physicians being mindful of tropical diseases in our interconnected world.

Pregnancy makes someone more attractive to the mosquito species that transmits malaria.

Wearing tick repellent, covering up, and performing tick checks are the best Lyme prevention

Spraying repellents onto your clothes—and reapplying them—or donning impregnated bug-repelling clothes can help keep ticks away. Effective sprays include DEET, picaridin, or permethrin. Bug spray applied to the body should be applied on top of sunscreen, and only after the sunscreen has dried.

Florida reports 71 imported malaria cases annually—4% of all the US cases.

Children under 5 account for 76% of all malaria deaths in Africa

The main hypothesis for why the disease hits this age group the hardest is that children this young have still-developing immune systems. Pregnant women and people with HIV/AIDS are also at higher risk of severe infection.

10 locally acquired malaria cases were reported in the US in 2023—a surprise

The cases, reported in Florida, Texas, Maryland, and Arkansas, broke a 20-year streak since there had been no reported locally acquired mosquito-transmitted malaria in the country since 2003, when there was a case in Florida.

See this diverse list of vector-borne diseases

Human illnesses caused by parasites, viruses, and bacteria, and transmitted by a living organism—often small, bloodsucking ones like mosquitoes, ticks, and sandflies—are known as vector-borne diseases. That carrier is called a vector. These diseases disproportionately affect the poorest populations in tropical and subtropical areas.

Birds, rodents, monkeys, lizards, bats, apes, and livestock can all get malaria—just like humans.

The mosquito's role in the transmission of malaria was confirmed in 1897.

Researchers are breeding genetically modified mosquitoes to be malaria-resistant.

'Sloth fever' is an emerging health threat, especially to pregnant women

This disease, caused by the Oropouche virus, is found in animals including sloths, primates, and birds. It primarily spreads through the bite of midges—insects commonly called "no-see-ums." It's endemic to the Amazon region, but US travelers are increasingly contracting it internationally.

See the geographic spread and incidence of malaria

This graphic shows the estimated global burden of malaria in 2025 as new cases per 1000 people at risk.

When planning a vacation, consider avoiding the peak tourism season at your destination.

How Disney World keeps out mosquitos

Disney World may have been built on a swamp, but it's nearly free from the annoyance of mosquitos. That hasn't been an easy task; Disney has worked with engineers and pest specialists on minimizing the invasive bugs through a variety of different methods. This Reader's Digest article breaks down how they've successfully kept the park free from these unwanted guests.

Molecular evidence suggests the deadliest malaria parasite may be 100,000 years old.

Treating black fever can result in a complication that spreads the deadly disease

Black fever, a deadly parasitic disease second only to malaria, threatens more than 1 billion people across more than 83 countries. Also known as kala-azar or visceral leishmaniasis, the disease is caused by parasites that spread through sandfly...

Explore inside a mosquito factory where millions of mosquitoes are bred weekly

In Medellin, Colombia, scientists are infecting Aedes aegypti mosquitoes with Wolbachia, a bacterium that wouldn't otherwise infect the species, but does block its ability to transmit dengue, Zika, yellow fever, and chikungunya. In the wild, infected mosquitoes would breed with wild mosquitoes, pass down Wolbachia, and thus reduce disease transmission.

There may be 500,000 additional malaria deaths by 2050 according to peer-reviewed research published in 2026.

Wolbachia is a naturally occurring bacterium being employed to fight dengue

Scientists are fighting dengue spread in a roundabout way: injecting bacteria into Aedes aegypti mosquito eggs, which blocks the dengue virus from replicating in the tissue of mosquitoes. Researchers hope the bacterium will be passed to future generations, inoculating them against dengue. Wolbachia is also being investigated to combat other mosquito-borne diseases.

Vector-borne diseases kill more than 700,000 people globally each year—and are growing

The diseases with the greatest potential to spread widely aren't the ones that quickly kill human hosts. Instead, the best hosts or reservoirs for vector-borne diseases would be chronically ill over the long term, increasing the likelihood that the pathogen could be transmitted to others.

Wolbachia: the bacteria that could eliminate dengue fever

Dengue fever, transmitted by mosquitoes, kills more people annually than all types of natural disasters combined. However, mosquitoes that host Wolbachia bacterium have their ability to transmit the virus naturally suppressed, offering a route to eliminating nearly 25,000 deaths annually.

Disney World is largely mosquito-free, thanks to civil engineer Joe Potter

As a former governor of the mosquito-prone Panama Canal zone, Potter understood the danger of standing water. At Disney, Potter built ditches to reduce moisture, designed buildings to channel water away, and more. His efforts help visitors avoid bites, adding to the perceived magic of the magical kingdom.

Some mosquitoes are key pollinators—and eat disease-carrying mosquitoes.

A French Army surgeon discovered that malaria is a parasitic disease in 1880—but scientists were initially skeptical.

The most effective method of managing invasive species is prevention education

Controlling a spread after a species has become established in an area is much more costly and time-consuming than early detection and rapid response. Control methods include the purposeful introduction of predators, the use of pesticides, herbicides, fungicides, and insecticides, and physical collection and removal.

Malaria mosquitoes in a lab were wiped out using CRISPR

Scientists at Imperial College London disabled a gene in female Anopheles gambiae mosquitoes to make them infertile and propagated the infertility mutation at unnaturally high rates using a gene drive. The entire population collapsed within a dozen generations, showing promise for subsequent with mosquitoes in mimicked tropical environments.

Mosquitoes are the world's deadliest animal, but gene drives could kill them.

The 'kissing bug disease' occurs when a bug's parasite-laden poop gets into your blood

Chagas disease transmission can occur when triatomine bugs bite someone infected with a Trypanosoma cruzi parasite and then bite someone else, passing on the pathogen, though the parasite can also be transmitted in other ways, including via food, congenitally, and through blood transfusions. The bugs tend to feed at night and can bite anywhere on the body, but their reputation for biting people around the mouth and eyes created the idea that the bugs were "kissing" humans. Recent research suggests the disease may be endemic in the US.

Mosquito saliva acts as an anticlotting agent

The bug's piercing mouthpart, the proboscis, is actually several tubes—one for sucking, one for spitting. But the chemicals in its spit actually help its blood meal to flow, combating its victim's ability to clot at the puncture site.

Using mosquitoes to vaccinate bats could curb the spread of deadly diseases.

Invasive species can harm infrastructure and threaten human health

The wildfires in Hawaii in 2022 were made worse by flammable invasive grasses introduced from Africa as livestock pasture, and Zebra mussels native to the Caspian and Black Seas have spread across Europe and the US, where they can clog power plant pipes. Invasive mosquitoes can carry diseases, such as dengue and malaria.

Bedbug problems have been increasing, and some 2023 research suggests the tiny insects may be capable of spreading 'superbug' MRSA.

Mosquitoes top the ranking of the world's deadliest animals.

Dr. William Gorgas eradicated yellow fever in Panama, crucial to canal construction

The disease was one of the factors hampering the French effort to build the canal. Gorgas' experience elsewhere in the Caribbean had taught him that good drainage and quaranting patients were essential, and he would eventually apply mosquito prevention tactics on a mass scale.

Tips for reducing the risk of antimicrobial resistance

Antimicrobial resistance is bad news. But there are lots of things you can do to both protect yourself from superbugs and help keep the problem of antimicrobial resistance from getting worse. This page from the CDC offers clear, straightforward guidelines that can help keep you—and your loved ones—healthy.

Eating street food while traveling isn’t recommended, but there are ways to do it more safely

The US Centers for Disease Control and Prevention urge people to stay away from street food while traveling. But if you still want to eat it, the agency recommends making sure it’s cooked food and that it’s served steaming hot. Also, avoid eating any raw vegetables as they may be more likely to harbor pathogens.

Wolbachia is also being used to slash mosquito numbers

The naturally occurring bacterium does not naturally infect Aedes aegypti mosquitoes, but communities in locations including California and Texas have released male mosquitoes infected with Wolbachia and reported a significant drop in subsequent mosquitoes: When infected males mate with uninfected wild females, the eggs don't hatch.

MS risk is shaped by geography, not just genes

Latitude—and related vitamin D exposure—seems to affect MS risk. People who migrate from a high-risk MS latitude (like northern Europe or the northern US) to a lower-risk latitude (like tropical areas) before age 15 tend to adopt the lower risk of their new country—suggesting there's a critical window for environmental exposure.

More than 20 mosquito-borne and tick-borne diseases are found in the US

Children, older adults, and people with compromised immune systems are at particular risk of poorer health outcomes from these diseases. But dog owners and outdoor enthusiasts are among those at particular risk of contracting these illnesses, which include Lyme disease, Zika, and the condition Alpha-gal Syndrome.

How we helped make Aedes aegypti mosquitoes such a problem

Mosquito genome sequencing data suggests that Aedes aegypti mosquitoes first started specializing on human blood around 5,000 years ago—when climates shifted and humans started domesticating plants in Africa and stored large amounts of water that may have attracted the bugs.