What are the phases of migraine?

What happens to the brain during migraine?

Migraine is a neurological condition that can cause debilitating symptoms across various bodily functions. So, what exactly is happening in the brain during these attacks? This five-minute video briefly overviews the internal machinations behind the painful episodes. An incapacitating headache is a common symptom of migraine, though migraine can occur without any headache.

What is a migraine attack like?

Are you one of the lucky people who've never experienced a migraine? Take the neurological condition for a whirl in this virtual experience sponsored by Excedrin, a pain relief medication brand. This 360º video is less than two minutes long and shows a snippet of an oncoming migraine suffered by a pastry chef.

Migrane 101: data, symptoms, and treatments

Living with migraine, however often the neurological condition attacks, is a journey fraught with pain and isolation. This migraine guide offers insight into the condition, common triggers, possible treatments, personal stories, and tips for managing life with migraine.

Headache disorders have historically been neglected and under-researched

Confusion between the variety of headaches—from mild discomfort to debilitating pain—and gender bias—migraines primarily affect women—have led to widespread misunderstandings of the medical issue. Medical students in the US may get as little as 30 minutes of instruction on the three major types: migraines, cluster headaches, and tension-type headaches.

New drugs called Gepants have been shown to improve the quality of life of many sufferers.

Journalist Eva Wiseman has had migraines since childhood. Beginning with a yawn they segue into visual auras before turning into severe pain. As it so happened, she experienced a migraine during the course of her interview with Dr. Peter Goadsby, a pioneer in understanding and treating migraines as well as getting the world to treat them seriously.

Understanding the stages of sleep

Do you have trouble keeping the different stages of sleep straight and organized in your mind? Us too. Sometimes it helps to have a straightforward listing of what each stage is and why it’s important. Look no further than this resource from Lumen. It is a basic outline of the four stages of the sleep cycle, along with the brainwaves and attributes that characterize each. If you’re brave enough, test yourself on the built-in quiz!

Why say 'migraine' instead of 'migraines'?

Language choice can affect people's assumptions and beliefs about the subject at hand, which is why some would prefer "migraine" to be treated as a singular and plural noun. This American Migraine Foundation article examines the logic behind the grammar choice.

20% of patients with migraines may also experience vertigo

Vestibular migraine is a common cause of vertigo, affecting approximately 20% of patients with migraine. It's the most common cause of recurrent, sudden-onset vertigo.

See this graphic of the complex malaria transmission lifecycle.

There are multiple types of multiple sclerosis—they differ by attack patterns

When your immune system targets the nervous system, this can cause new or worsening symptoms and the development of scarring or damage within the central nervous system. Relapsing-remitting MS is the most common type of the disease—it includes progressive bouts of attacks that occur months or years apart.

Drugs 101: An interactive guide

What's the difference between opioids and psychedelics? This guide details specific drugs and their various associated effects. Drugs in this wheel fall into seven categories: stimulants, depressants, empathogens, psychedelics, dissociatives, cannabinoids, and opioids.

The two phases of stress: fast and slow

The physiological response to acute stress generally involves two phases—the "fast" response in which adrenaline is released, and a second "slow" response in which cortisol is released. This technical resource reviews what happens in the body during each phase.

Your brain appears to age in five distinct stages, with the pattern of connections inside your brain shifting, on average, around ages 9, 32, 66, and 83.

Annuities have two core phases: the accumulation phase and the annuitization phase

During the accumulation phase, individuals invest in their annuity with financial contributions. The annuitization phase is when the annuity is paid out.

Visualize a stroke at the microscopic level.

Can brain scans help with processing trauma?

MRIs and brain monitoring therapies are becoming increasingly popular for those looking to process trauma and address mental health conditions, including PTSD and depression. This article details how these therapies quantify mental health, giving users another way to measure and manage their mental and emotional needs through brain mapping and other methods.

Explore this week-by-week visualization of pregnancy

This graphic illustrates how development proceeds during each week of pregnancy, tracking what shifts and milestones typically occur during each stage of the process. It also includes typical weights of the fetus throughout.

Changes in vision or eye pain can be early MS symptoms

This occurs due to myelin degradation around the optic nerve, impairing its ability to transmit visual information to the brain. Individuals may especially experience eye symptoms after exercising or taking a hot shower because boosted body temperatures slow down nerve function in nerves already damaged by MS.

Someone suffers from a stroke every 40 seconds

Every 40 seconds, someone in the US experiences a stroke—and every minute without treatment destroys millions of brain cells. This explainer breaks down the two main types of strokes, their risk factors, and how early detection could change outcomes in the future.

What happens when we sleep

Sleep is a highly specialized and complex process that begins via signals from a region of the brain called the hypothalamus. As explained in this overview video from The Economist, the hypothalamus maintains our circadian rhythm by using light cues from our environment to regulate sleep via a compound known as melatonin. Once asleep, the brain begins the "sleep cycle" and progresses through the four stages of sleep over and over again each night.

Your brain moves through four distinct sleep stages every night

Each stage plays a key role in memory, repair, restoration, and other key biological functions. The full cycle generally proceeds from light sleep and deep rest into vivid REM dreaming, which repeats between three and five times nightly.

See the geographic spread and incidence of malaria

This graphic shows the estimated global burden of malaria in 2025 as new cases per 1000 people at risk.

Visualize the difference between a healthy brain and one with Alzheimer's.

Misophonia is a neurological disorder where sounds trigger strong emotions

The phenomenon is characterized by decreased tolerance to specific sounds, such as heavy breathing, pen clicking, and water dripping, which trigger a fight-or-flight response. The resulting emotions, which can range from irritation and disgust to anxiety and fear, can be overwhelming and uncontrollable.

How MS is diagnosed with brain and spinal cord MRIs and eye tests

There's no definitive test for MS, but to make a diagnosis doctors typically use MRIs of the brain and spinal cord to hunt for telltale lesions. Also, optic nerve tests to see how quickly information travels down the optic nerve—since degraded myelin sheaths will slow electrical signals between the eye and brain.

Why dizziness is still a mystery

Dizzy spells can completely upend the lives of those suddenly struggling to find their footing. Despite this severe impact, the different flavors of dizziness and their sources continue to elude medical understanding. This article follows a health...

View a gallery of various auroral shapes

Auroras can be generally classified as discrete (well-defined shapes) or diffuse (hazy shapes), with light taking various forms, including curtains, arcs, pillars, and rays. Some auroras can also pulsate, particularly after intense periods of auroral activity are winding down.

The five stages of grief—and what to do when yours doesn't follow this model

The "five stages of grief" is a well-established process used by many to move through periods of mourning. Grief is notoriously difficult to manage, and such procedures help move people forward. Only, what happens if your experience doesn't match the model at all? This podcast episode explores one researcher's unique approach to processing her own grief.

Explore a visually captivating, interactive animation that lets users click through anxiety-inducing scenarios, make choices, and see the repercussions.

A list of common questions and answers about hurricanes from NOAA

This FAQ answers many questions hurricane researchers at NOAA have received, sorted by category. The answers provide insights into hurricane classification and naming, forecasting their movement and growth, and tips for preparing ahead of landfall.

Explore these images to better understand why food poisoning makes you feel nauseous.

See this first-person virtual reality view of vertigo

This video shows a virtual reality environment view of what benign paroxysmal positional vertigo will look like, from a first-person view. It includes a virtual rendering of eye spinning associated with the condition. (Warning: Watching this may make some users feel a bit nauseous.)

How four types of psychedelics affect the brain

Brain imaging shows that ayahuasca, MDMA, DMT, and psilocybin profoundly affect neural activity, giving rise to higher states of introspection and consciousness. This article details exactly how each of these drugs physically affects the brain and what that means for mental health treatment. Some of these drugs quiet the brain or trigger the release of neurochemicals associated with mood regulation and learning.

Learn about the basic anatomy of mosquitoes

This short explainer video breaks down the mosquito's general body components, highlighting how mosquitoes breathe, fly, and more. It also touches on how experts can tell different mosquito species apart.

Vestibular Paroxysmia is often overlooked as a vertigo-causing diagnosis

VP causes brief, recurrent episodes of vertigo. It's often mistaken for the more common "benign paroxysmal positional vertigo," but its vertigo episodes are typically shorter and triggered by specific head movements. The condition is caused by compression of the eighth cranial nerve. Other symptoms that accompany it are nausea and unsteadiness and, more rarely, tinnitus and hearing changes.

When common sounds become disturbing

Misophonia causes certain sounds to feel violating, triggering a "very visceral kind of experience" filled with extremely unpleasant emotions, including annoyance, anger, and disgust. A 2017 study found that people with misophonia have elevated activity in the brain's anterior insula—a region associated with interoception, emotional processing, and behavioral responses—when exposed to trigger sounds. Ongoing research suggests trigger sound context affects the severity and manifestation of the condition.

Multiple sclerosis means 'many scars'

That's a reference to the scarring or lesions that occur in the brain, spinal cord, and elsewhere whenever the immune system has a flare-up. The immune system attacks the myelin because it incorrectly responds as if it's a threat, damaging the body's ability to transmit electrical signals effectively from areas of the body to the brain.

Untreated malaria can lead to blocked blood vessels in the brain, coma, and organ failure.

The second phase of acute stress: the 'slow' response

The body's reaction to acute stress involves two responses: fast and slow. The first occurs immediately, with the central nervous system triggering the release of adrenaline. The second releases cortisol, which elevates blood sugar and blood pressure and restricts nonessential functions like digestion and the immune system.

How do hurricanes form?

Tropical cyclones, also called hurricanes and typhoons, cause catastrophic damage when they strike land. This four-minute video explores the life cycle of cyclones—how atmospheric conditions, ocean temperatures, and the Earth's rotation combine to create them, and how they are driven by winds and eventually weaken after moving over land.

How menopause affects mental health

Menopause, a natural biological process, occurs in three stages: perimenopause (hormone fluctuations), menopause (end of menstrual cycles), and postmenopause (12 months without menstruation). Hormonal shifts during this time can affect neurotransmitters, increasing the risk of mood disorders.

An interactive guide to the cardiovascular system

The cardiovascular or circulatory system moves blood throughout the body, ensuring cells have necessary nutrients and removing any waste. Click through this interactive 3D guide to explore the system as it crisscrosses the body via arteries, veins, and capillaries. This guide also includes similar breakdowns of the body and its other processes.

How the moon moves, an interactive lesson

How exactly does the moon move, and why does it move that way? In this ridiculously comprehensive interactive explainer, you can conduct experiments to see how the moon rotates and as it moves around the Earth, while learning how gravity works by controlling the path and speed of different objects. Dive into this beautiful, simple explainer to learn the basics on gravity and the moon.

What happens in a dying brain?

Near-death experiences usually happen during death or on the border of life and death when a person isn't understood to be conscious. This article details the science of what's going on with the brain during NDEs.

Learn about the point of the physical and emotional experience of pain, which has three broad categories that help determine treatment approaches.

Learn the differences between mild cognitive impairment and age-associated memory loss

Mild cognitive impairment is a condition in which people experience more thinking and memory problems than expected for their age. It's often associated with depression and anxiety. Daily routines, writing things down, and healthy lifestyle choices can help cope with the condition, but there's no cure. The condition elevates the risk of developing dementia and Alzheimer's.

Menopause affects the brain in complex ways

Lisa Mosconi, a neuroscientist studying the impact of menopause on the brain, explains in this video how menopause directly impacts a woman's brain health and explores why this is an important and often overlooked area in menopause and women's aging healthcare discussions.

How the brain processes a calendar year

When most of us picture a calendar year, we have a foggy image in our minds of the months, in rough, calendar-like grids. But for some folks, that picture is a whole lot more clear. Around 1 percent of the population has a strange ability known as "calendar synaesthesia," which means they're able to visualize in crisp detail an elaborate calendar of the months of the year. Learn how it works here.

Sharp wave ripples in the brain tag experiences for long-term memory storage

These ripples were known to quickly replay neuronal sequences during sleep for consolidation. While awake, they help the brain prioritize memories to remember, and their disruption can impair memory formation.

AI vs. machine learning vs. deep learning

Machine learning is best understood with visuals. A collection of the best 9 images, videos and flowcharts that explain what it is and how it works.