Long-haul COVID: What doctors want patients to know

Based on its varied symptoms, scientists think that long COVID is not a single disease, but rather a group of different conditions triggered by COVID-19 infection.

The rise of telemedicine: A post-pandemic analysis

Before COVID-19, telemedicine remained on healthcare's periphery; however, the pandemic thrust it into the limelight, transforming how we approach medical care. This comprehensive review published by Press Ganey dives deep into the evolution,...

COVID accelerated antibiotic resistance

The COVID-19 pandemic was caused by a virus, and viruses can’t be treated with antibiotics. But recent research finds that COVID patients were given a tremendous amount of antibiotics, contributing to the problem of antibiotic-resistant bacteria. Why? This NPR feature sheds light on an unexpected side effect of the pandemic.

Why dizziness is still a mystery

Dizzy spells can completely upend the lives of those suddenly struggling to find their footing. Despite this severe impact, the different flavors of dizziness and their sources continue to elude medical understanding. This article follows a health...

Loss of sense of smell is a common symptom of COVID-19 infection

In 2020, researchers discovered why this occurs. The virus that causes this infection attacks the cells that support smell-detecting neurons. Once infection clears, the sense of smell typically returns, though the exact timeline for that differs by patient. (Some users may experience a paywall.)

Patients are messaging their doctors online more than ever—recent research suggests portal messages have risen by 157% since 2020.

Watch an expert's take on the rare disease hantavirus—and why it's not of great concern to the general population

This rare zoonotic disease, transmitted to humans primarily through infected rodent droppings, urine, or saliva, is rarely spread between people. The disease was of particular concern in spring 2026, when an outbreak occurred on a 150-person cruise ship, prompting a flurry of action, including contact tracing for passengers in their home countries. The disease can be fatal. But early care—primarily oxygen support—can help patients survive.

Post-treatment Lyme disease syndrome may be caused by bacterial remnants in the liver

PTLDS, which refers to lingering symptoms of Lyme after antibiotic treatment, is an area of active research. Rodent research published in 2025 suggests that these ongoing symptoms may potentially be due to the body's inflammatory response to lingering cellular components from the bacteria that cause Lyme, Borrelia burgdorferi. In rodents, components of the bacteria's cellular wall may remain in the liver after the bacteria were eliminated with antibiotics.

Read the Surgeon General's 2023 loneliness report claiming loneliness is an epidemic

This report details the specific health threats linked with loneliness, including that loneliness and social isolation can increase the risk of premature death by nearly 30%. Loneliness lowers our capability to mount an effective immune response to viruses and respiratory illness, can cause chronic inflammation on par with physical inactivity, and increases the risks for anxiety, depression, dementia, heart disease and stroke.

How did the pandemic affect mental health?

Read this research brief to learn more about why heightened mental health and substance use concerns persist three years after the outbreak of COVID-19. According to a recent survey, the vast majority of American adults view the nation as facing a...

A doctor answers the internet's burning questions about the gut

Gastroenterologist Dr. Ugo Iroku answers the internet's burning questions about digestion and bowel movements. Get the lowdown on what it means when your stuff is super dark, the impact of coffee on evacuating bowels, and much more.

Chronic lyme isn't a medically recognized diagnosis in conventional medicine

It describes a constellation of symptoms attributed to a persistent Lyme infection—meaning the bacteria have remained present even after antibiotics. It often occurs among people who have never received a positive test for Lyme. Doctors do recognize "post-treatment Lyme disease syndrome," however, which can include muscle and joint pain, fatigue, and cognitive difficulties after treatment for confirmed Lyme.

Olfactory training, a widely recommended treatment for people with long-term loss of smell after a viral infection like COVID, can be performed at home using bottles of essential oils—often lemon, rose, clove, and eucalyptus—to help reorganize neural connections in the brain.

Tinnitus is a rare side effect of COVID-19

The infection can affect inner ear cells, and a review of the literature across multiple studies concluded that hearing loss occurred in 3.1% of patients with the virus and tinnitus in 4.5%.

A malaria case in Maryland stumped doctors in 2023—leading to the wrong treatment and underscoring the challenge of physicians being mindful of tropical diseases in our interconnected world.

Patients are a part of the progress

Navigating a cancer diagnosis can be terrifying and overwhelming. There is a robust community of patient advocates dedicated to prevention and diagnosis, research and clinical trials, legislation, needs of individual cancer types, among others. See how patient advocacy improves cancer research leading to improved treatment options and patient care.

Simulation of the coronavirus inside an aerosol droplet

A new simulation shows how the virus survives inside tiny airborne particles of water — and gives clues about how the Delta variant became dominant.

Why we don't have an answer for the common cold

Since a landmark study of the common cold in 1925, researchers have learned much more about the seasonal ailment. Despite continuous study, people still contract colds for similar periods of time at the same rate with the same symptoms, and there's no vaccine. This article explains how the many viral strains make it hard to control.

After a dementia diagnosis, it's important to plan ahead but also savor the moment

The next steps after a diagnosis include taking lifestyle steps to slow disease progression and completing legal paperwork about long-term medical preferences. It's also important to appreciate the moments and days ahead and find humor in them, when possible. (Some users may encounter a paywall.)

Measles infection can cause long-term immune system “amnesia”

The measles virus attacks the body's immune system, including preying on T and B cells in the lymphatic system. These cells hold memories of past infections, which can be degraded as the virus destroys them. This leaves patients susceptible to other infections for a year or longer.

Visualizing the genetics of SARS-CoV-2

The COVID-19 pandemic, caused by the SARS-CoV-2 virus, began with an outbreak in Wuhan, China in December 2019, and rapidly spread worldwide in early 2020. On March 11, 2020, the World Health Organization declared COVID-19 a global pandemic, leading to widespread lockdowns, travel restrictions, and economic disruptions.

Nonwhite Lyme patients tend to be diagnosed later and have more severe disease

Peer-reviewed research published in 2025 from Pfizer—a pharmaceutical company working on a candidate vaccine for Lyme disease—examined Lyme data from more than 150,000 Medicare and Medicaid beneficiaries and found that Black patients, as compared to white beneficiaries, were more likely to have disease that had spread further throughout the body at the time of care. The difference, the scientists wrote, may be partly due to difficulties recognizing the characteristic rash on darker-colored skin.

Long-term memory issues among West Nile survivors may be from the body's immune response, not the viral infection.

Roughly 45% of clinicians in 2023 reported at least one symptom of burnout

With that kind of statistic as a backdrop, proponents of concierge medicine practices argue that concierge services could help keep doctors in medicine and thus help to address physician shortages.

Environmental conditions, shifting immunity, and viral strain could help explain 2025 spike

The surge in HFMD in the summer and early fall of 2025 in the mid-Atlantic could be the result of a confluence of factors, including a more virulent strain of disease-causing virus, good environmental conditions for the virus to spread—hot, humd—and a potential immunity gap among kids due to milder HFMD outbreaks the previous year.

Patient portals offer a good opportunity to track your healthcare records and communicate with doctors, but they also allow patients to see test results without context, which can cause unnecessary concern.

A 40-something science journalist was getting more winded during workouts, and experiencing night sweats, forgetfulness and tiredness—she thought it was perimenopause, but these common symptoms turned out to be signs of her blood cancer.

The basics behind mRNA vaccines

In this video, Yale experts Saad Omer, MBBS, MPH, PhD; Onyema Ogbuagu, MBBCh; and Akiko Iwasaki, PhD, explain the science behind COVID-19 mRNA vaccines.

Scientists from the frontline discuss the future of antibiotics and superbugs

Superbugs are a very real problem, but researchers around the world are working to advance our understanding of these pathogens and develop new medicines. This podcast talks with several scientists on the frontier of superbug research, offering insight into what we know—and what the future of medicine may look like.

Lengthy incubation periods are why it's tough to link foodborne illness to specific foods.

Links between long-term caregiving and chronic stress

This Cleveland Clinic overview suggests that around 60% of people caring for family or loved ones with health conditions will experience burnout. Caregivers prepare meals, help with transportation, administer medications, and perform daily tasks for others, all while managing their own lives. This guide may help readers overcome the guilt or frustration of long-term caregiving to seek alternative options.

Adults usually have some immunity to HFM Disease—but can still spread it

In 2025, certain eastern states including Virginia and West Virginia reported a sizable uptick in their HFMD cases, particularly in their schools and daycare centers, though the reason for the larger outbreaks remains unknown. When adults or teens get the disease, their symptoms are usually mild or even asymptomatic. Still, they may pass the disease between people, too. (Some users may encounter a paywall.)

A radiation oncologist has studied near-death experience reports for over 25 years and compiled around 4,000 accounts in the hopes of finding more patterns that would reveal insights about consciousness and humans' final moments before or around death.

The lack of diversity in clinical trials is undermining the future of precision medicine

Medicine works better when the treatments are tailored to fit each individual person’s biology and history. Homogeneous patient selection in clinical trials means treatments and care are being refined based on only a small range of variables, some of which may not apply to you. This 40-minute podcast episode discusses the historical and current reasons for the lack of clinical trial diversity and what this means for the future of personalized medicine.

Read a study about racial differences in Lyme disease diagnosis

The research published in September 2025 examined differences in Lyme disease diagnosis among Medicaid and Medicare beneficiaries using data from 2016 to 2021. It notes that though US Lyme disease surveillance data indicates more than 90% of diagnosed Lyme cases are among white people, people of color—particularly those who identify as Black or African American—have higher rates of more severe disease of Lyme, with symptoms including arthritis and neurologic impacts.

Vector-borne diseases kill more than 700,000 people globally each year—and are growing

The diseases with the greatest potential to spread widely aren't the ones that quickly kill human hosts. Instead, the best hosts or reservoirs for vector-borne diseases would be chronically ill over the long term, increasing the likelihood that the pathogen could be transmitted to others.

Doctors report wanting more time to plan, provide care for patients

Many physicians experience aspects of burnout, and concierge medicine provides a slower, more relational approach to medicine, including consistent follow-up care for a smaller pool of patients. A concierge medicine clinician may talk with each patient frequently, perhaps every few weeks, instead of just once a year.

The gut microbiome's community of viruses is collectively known as the virome, but most of its viruses remain unidentified.

A timeline of major pandemics from 1899–2025

Modern pandemics have been defined by the race between globalization (which increases risk) and the development of new medicines. The Great Influenza epidemic claimed some 50 million lives, and the COVID-19 pandemic killed more than 7 million. In between, diseases like Ebola, cholera, AIDS, and more have devastated communities.

Meeting someone with common healthcare challenges can be life-changing

The understanding that comes from meeting others who have similar experiences can provide hope that life can get better, the solace of affirmation, and make navigating a new diagnosis or a rare illness, in particular, much easier.

Watch patient stories describing life with macular degeneration

This video series features patients discussing their experiences with the disorder, family members describing caregiving, and other insights about the disease.

'Tomato flu' outbreak in India turned out to be HFMD

An illness initially dubbed "tomato flu" in 2022 that sickened children in Kerala, India, with symptoms typical of hand, foot, and mouth disease turned out to be that—not a new ailment. A letter published in the prestigious journal The Lancet had initially described the illness as "a new virus" but at least some of the children ultimately tested positive for one of the viruses that causes HFMD, so it wasn't a new condition after all. (Some users may encounter a paywall.)

A sleep expert discusses the broad benefits of quality rest

In this three-part series, renowned sleep expert Matthew Walker and doctor Peter Attia explore the role of sleep in memory consolidation and mental health, and the detrimental effects of chronic lack of sleep. The latter has been linked to increased risk of dementia, hypertension, and more.

Experience a century of America's healthcare advances with this medical visualization, tracing a sampling of healthcare innovations from head to toe.

Addressing lifestyle factors, which influence inflammation, can cure some chronic diseases

In this video, a physician claims that he reversed a patient's Type 2 diabetes in six weeks by addressing inflammation drivers such as diet. More broadly, he argues that society needs to better consider and address numerous disease factors that are modulated by inflammation, such as stress, sleep, diet, and movement.

How the 1918 pandemic spurred developments in virology and vaccines

This article provides an in-depth historical account of the 1918 Spanish Flu pandemic, including its impact on the global population and how its occurrence spurred significant advancements in the study of viruses—laying the groundwork for the...

Clinical burnout: prolonged exhaustion, mental distance, and persistent negative feelings

Burnout isn’t just stress—it’s a pervasive feeling of exhaustion that can start in the workplace and seep into everyday life. It causes feelings of dread and cynicism about work tasks. On top of emotional distress, there can be physical symptoms and a tendency towards addictive behavior.

Depression changes the brain, causing distinct structural alterations visible on brain scans, but effective treatment can eventually make a depressed brain resemble a healthy one.

Most flu cases are treated at home, but antivirals help high-risk patients

Rest, fluids and common medicines usually ease influenza symptoms. For people at higher risk of complications, doctors may prescribe antiviral drugs, which work best when started soon after symptoms begin.

Before vaccines, there was 'variolation': what was it?

Before the technology behind vaccinations was discovered, some keen observers of medicine around the globe noticed how previous infections could impact future ones. Learn about the techniques early physicians used before they had vaccines.