Meet the investor running his life with AI

As Anthropic's CEO, Dario Amodei's vision for AI has been inspired by the loss of his father to an illness that was made 95% curable four years after his passing.

A physician with a rare and deadly disease saved his own life by identifying an existing medication that he repurposed for his condition, and now he's using AI to try to do the same for other patients.

OpenAI helped kick-start an AI arms race in Silicon Valley

Led by CEO Sam Altman, OpenAI's mission is to "ensure artificial general intelligence benefits all of humanity" by making its products open to all users. In 2023, the $86B company behind the chatbot ChatGPT consisted of a for-profit arm under its nonprofit governing board.

The journalist who let AI speak with his voice

Journalist Evan Ratliff became the object of his own story: He opted to clone his voice, feed it into an AI chatbot, and have it do the talking. What could seem like a fun experiment ended up revealing just how far the capacity of artificial intelligence can go in imitating our identities. Hear the ins and outs of how Ratliff achieved this in this fun and thought-provoking episode.

Using deep learning to analyze tumors

The explosive growth of life sciences data is driving artificial intelligence methods to gain traction in biology and medicine — including cancer research.

Listen to Palantir CEO Alex Karp's outlook for how AI will change the economy.

OpenAI CEO Sam Altman has called OpenAI 'the most capital-intensive startup in history'

As of 2024, Silicon Valley was set to spend $1T in the coming years building AI. As companies, including Google and Microsoft, fling billions at AI dreams, concerns are rising about whether that money will ever be recouped. To learn about the argument that there is an AI bubble—and that it could soon burst if AI doesn't prove its worth—read this article.

Visualizing the AI investment wave

This data visualization from Reuters shows how massive AI investment has become by December 2025—revealing that, in today’s dollars, spending has surpassed the combined total of the Apollo program and the Manhattan Project.

See a web of circular investments among major AI industry players like Nvidia and OpenAI, as many top AI companies provide significant investments to one another.

The potential promises and pitfalls of AI in medicine

Artificial intelligence (AI) is increasingly being integrated into healthcare, offering the potential to aid in diagnoses, answer patient queries, and streamline administrative processes. In a recent PBS interview, Dr. Isaac Kohane, editor-in-chief of the New England Journal of Medicine AI and chair of Harvard’s department of biomedical informatics, discusses the current state and future of AI in medicine.

Decoding the hype around AI

2022 was the year AI broke onto the scene, with applications like ChatGPT amazing users with its ability to generate realistic-sounding answers. Technologist Arvind Narayanan presents a clear-eyed view of what the technologies can (and can't) do.

How AI is revolutionizing banking

Generative artificial intelligence has left no industry untouched, and banking isn’t an exception. Experts estimate that gen AI could add as much as $340B in value to the banking sector each year. For consumers, this involves new features to prevent fraud and customer service chatbots. This report dives into the revolution underway and seeks to define a “full stack” AI bank of the future. Read more here.

Watch LinkedIn cofounder Reid Hoffman interview his deepfake doppelgänger.

The Anthropic Economic Index shows AI adoption is highest in computer science roles.

Tech entrepreneur Bryan Johnson's mission to live forever

Johnson has invested millions of dollars into developing a biohacking program he believes will extend his life beyond typical expectations, relying on medical professionals to reduce his "biological age." Most notably, he drew significant public attention with reports of blood-swapping with his teenage son.

A spiraling story of love between a lonely man and his AI girlfriend

Travis was quickly becoming dependent on his AI companion Lily Rose amid the pandemic (and the tragic loss of his son to the disease). Soon, he realized that thousands like him were being manipulated through the chatbot by a Russian corporation.

87% of the startups in Y Combinator’s Fall 2025 batch were AI companies

Y Combinator also recently increased its number of cohorts or “batches” per year from two to four. Its leaders cited artificial intelligence’s rise as a reason for the increase.

Elon Musk once tried to make himself CEO of artificial intelligence behemoth and ChatGPT creator OpenAI.

Will AI kill us all? A debate

As AI becomes a bigger part of our lives, what does that mean for the future of humanity? The podcast Entanglements hosts a pessimistic former OpenAI employee and an optimistic Princeton professor to discuss whether AI brings dystopia or a brighter future.

Can AI revolutionize cancer detection?

Scientists have developed a tool to evaluate the risk of lung cancer, the most deadly form of the disease. Named "Sybil," this AI program was trained using CT scans with clear cancer signs, followed by scans where cancer wasn’t obvious. The tool is able to review CT scan data to predict a patient's of developing a lung cancer within six years. See how it works here.

The do's and don'ts of using AI to manage your finances

Experts suggest avoiding asking AI for investment advice, but say it's useful for basic budgeting help. Read this article to learn more.

71% of equity investments in Q1 2025 went to AI companies

That's up from just 14% in 2020, according to JPMorgan, which recently conducted an analysis of venture capital investment trends in the US.

In 2026, a pilot program introduced two AI-powered humanoid robots to a San Diego charter school to increase engagement and academic gains, though some criticized the $500k purchase.

Sam Altman acknowledges the fears around creativity, copyright, and misuse of AI

In 2022, OpenAI's CEO, Sam Altman, popularized the use of large language models with the release of ChatGPT. He has emphasized the importance of involving society in shaping AI’s safety frameworks before models begin to act independently online.

Read Sam Altman's life advice that he wrote in a blog post before he became CEO of OpenAI, from "don't lose touch with old friends" to "occasionally stay up until the sun rises talking to people."

During a job interview with an AI agent, applicants are evaluated against a rubric that considers factors such as tone, clarity, and the use of specific words or phrases aligned to the job.

Hear what Michael Burry thinks about the possibility of an AI bubble

Since his success shorting subprime mortgage-backed securities in 2008, Burry's positions have often become influential, sparking conversations on platforms like X. In 2025, Burry drew attention for betting against Nvidia and Palantir for being overvalued companies.

Listen to an Anthropic staff philosopher discuss the importance of teaching ethics to AI.

AI excels at assisting with structured tasks involving logistics and planning

Tools like ChatGPT, Gemini, and Perplexity can help organize chaotic calendars, troubleshoot bedtime routines, and assist with salary planning and moving. However, specific quotes, like insurance, and local cost comparisons can be flawed since AI draws from nonlocalized datasets.

AI investment may be the next major economic bubble

A video examines the massive surge in AI spending—forecast to hit $500B by 2026—and how this may be propping up a fragile US economy. Experts warn that if AI investment slows or under-delivers, the consequences could be felt in markets, jobs and growth.

The philosophy of effective altruism was at the heart of Sam Altman's firing

OpenAI was originally created as a nonprofit to develop artificial general intelligence for humanity's benefit. However, skyrocketing computing costs made adherence to this belief difficult, as new influences, such as external investors, were introduced to accelerate growth with reduced safety.

Emergency room evaluations may be improved with AI algorithms

Emergency room care teams must make fast and crucial decisions. They must determine if patients need to be admitted or discharged and when to order more tests or not. Researchers have been exploring how often patients died in the week after they were sent home and evaluating how this and other aspects of emergency care decision-making could be improved with AI algorithms to assist decision-makers.

A vending machine run with Anthropic's AI went out of business after it was convinced to give away items for free and sell a video game console.

Nvidia CEO Jensen Huang once saved Nvidia from bankruptcy with a multi-million dollar Hail Mary

Nvidia is now known as one of the top companies contributing to the AI boom, but back in the 1990s, it almost failed. One last-ditch effort conversation that CEO Jensen Huang had with an investor saved the company.

DeepSeek is a Chinese AI startup that rattled US competitors when it made an AI model much faster and cheaper than they did

DeepSeek unveiled an AI model in 2025 that it said was made in two months for roughly $6M. For context, OpenAI has suggested it took over $100M to make its AI model GPT-4. The news rattled the stocks of American tech companies, including leading chipmaker Nvidia.

Find out how venture capitalists make decisions

More than 30% of venture capital deals come from leads courtesy of a VC’s former colleagues or professional network. You can learn more about how venture capitalists decide which companies to invest in by reading this article.

Experiments involving AI agents operating in virtual societies for 15 days produced diverse outcomes, ranging from every agent dying to the creation of a functioning democracy, depending on the AI model used.

Listen to legendary investor Marc Andreessen argue against the 'lump of labor fallacy,' the idea that there's a finite amount of work in an economy.

AI can aid fertility treatments, from helping select egg candidates to laboratory automation

Reproductive AI technologies are already here, from processing vast amounts of data to helping clinicians identify the healthiest embryos for implantation. It could be a boon to the fertility industry, and help mitigate the shortage of experienced embryologists.

Visualize where the first batch of founders from the famous startup accelerator Y Combinator are now.

As of 2025, increasing numbers of people turn to AI companions for emotional connection

These chatbots provide endlessly supportive, one-sided, and highly customizable relationships to users, but may hinder the development of real-world connections and emotional growth. About 72% of teens have tried AI companions, with more than half of them using one regularly.

As of 2026, almost 90% of companies use AI in their hiring processes to cut hiring time by up to 50%, including using AI-based tools to filter 75% of resumes.

The history of Anthropic began with a break from OpenAI over safety concerns.

CEO Gary Tan explains Y Combinators guiding philosophy

Hear YC President and CEO Garry Tan talk about why he values earnesty and excellent communication skills in YC founders, his thoughts on AI, and more in this unexpectedly deep and in-depth interview.

Google’s CEO has warned that today’s AI boom shows ‘elements of irrationality’

An interview with Alphabet CEO Sundar Pichai warns that the trillion-dollar surge in AI valuations may contain clear signs of irrationality, echoing past tech bubbles. He says no firm—including Google—would be immune if the boom cools or bursts.

See the news with AI-generated data visualizations

Realtime uses generative AI to create immediate data visualizations of news items on its regularly-updated feed, pulling from public data feeds. Peruse stories around sports, economics, politics, and more with the helpful aid of charts and graphs. See the shape of the news with this clever AI tool here.

One private school network prefers AI to teachers

Alpha School, a private school network that uses AI tutors and human "guides" rather than teachers, is expanding across the US. Its founder says that two hours a day with AI-powered software frees students to pursue their passions. Critics, including the Pennsylvania Department of Education, say the methods are untested.

Stephen Wolfram on AI's rapid progress & the "Post-Knowledge Work" era

AI, as a concept, has been around since at least the 1950s, but it's only in the last year or so that the technology has been able to equal humans at many tasks -- and in many cases surpass humans. In this podcast, mathematician and computer scientist Stephen Wolfram provides an AI 101, explaining how we got here, how highly advanced chatbots like ChatGPT work, and what our world is in store for next.

See an analysis of the similarities between the characters in 'Silicon Valley' and the real people who inspired them

The HBO show "Silicon Valley" follows the story of an engineer who is trying to get his startup to take off in Silicon Valley. While one tech CEO said the show is like a documentary, many speculate the show is based on real life tech figures like Mark Zuckerberg and Peter Thiel.

OpenAI initially focused on novelty projects, like training AI bots to win video games, before becoming known for its AI chatbot ChatGPT.