As Anthropic's CEO, Dario Amodei's vision for AI has been inspired by the loss of his father to an illness that was made 95% curable four years after his passing.

A merger between OpenAI and Anthropic was reportedly proposed after Sam Altman's firing

OpenAI's board of directors reportedly reached out to Anthropic's CEO, Dario Amodei, about the possibility of taking over the role left by Altman in 2023. Amodei declined to take over as OpenAI's CEO and to a merger of the two AI startups.

How Anthropic's experimental corporate structure incentivizes safe AI development

As Anthropic is a public benefit corporation, its board is tasked with making sure that AI tools are developed to help people and society thrive. Members of its Long Term Benefit Trust hold no equity in the company, but make up a majority of the board and can act to maintain Anthropic's public benefit purpose.

Meet the investor running his life with AI

Daniel Ha is a venture capitalist who built a suite of AI agents to boost his productivity, both professionally and personally. At his VC firm, a troupe of agents gathers data on startups and analyzes it from competing perspectives to produce a confidence score. When his dad was diagnosed with cancer, Ha used an oncology-trained AI to help him understand the condition.

The history of Anthropic began with a break from OpenAI over safety concerns.

The philosophy of effective altruism was at the heart of Sam Altman's firing

OpenAI was originally created as a nonprofit to develop artificial general intelligence for humanity's benefit. However, skyrocketing computing costs made adherence to this belief difficult, as new influences, such as external investors, were introduced to accelerate growth with reduced safety.

Listen to an Anthropic staff philosopher discuss the importance of teaching ethics to AI.

The Anthropic Economic Index shows AI adoption is highest in computer science roles.

A physician with a rare and deadly disease saved his own life by identifying an existing medication that he repurposed for his condition, and now he's using AI to try to do the same for other patients.

OpenAI helped kick-start an AI arms race in Silicon Valley

Led by CEO Sam Altman, OpenAI's mission is to "ensure artificial general intelligence benefits all of humanity" by making its products open to all users. In 2023, the $86B company behind the chatbot ChatGPT consisted of a for-profit arm under its nonprofit governing board.

Dario Amodei explains what led to his company being designated a supply chain risk

When pressed about the use of Claude in the capture of former Venezuelan President Nicolás Maduro, Anthropic's CEO acknowledged its contract with the Pentagon. However, he also emphasized that Claude is not to be used for mass surveillance or autonomous weapons, in part because the technology is not yet safe or reliable for such uses.

Will AI kill us all? A debate

As AI becomes a bigger part of our lives, what does that mean for the future of humanity? The podcast Entanglements hosts a pessimistic former OpenAI employee and an optimistic Princeton professor to discuss whether AI brings dystopia or a brighter future.

Listen to Palantir CEO Alex Karp's outlook for how AI will change the economy.

How constitutional AI helps cultivate good human values in Anthropic's AI tools

By incorporating elements from documents such as the UN's Universal Declaration of Human Rights into a framework against which it can check its outputs, Anthropic hopes the approach will help Claude operate with good human values and behaviors beyond what human-driven training alone can provide.

In 2026, Pope Leo XIV published a 42,000-word document on AI, written with the advice of the Pontifical Academy of Social Sciences.

What does AI mean for the future of global healthcare?

The World Economic Forum's 2023 Technology Pioneers are a collection of groundbreaking leaders from over 30 countries who are striving to shape the future by addressing a range of global challenges. In the World Economic Forum's recent article, these pioneers convened to discuss the transformative potential of artificial intelligence (AI) and machine learning within the healthcare sector.

Anthropic's Claude Science is an AI workbench connected to more than 60 scientific databases, designed to assist scientific research in molecular and cellular biology and drug discovery.

Using deep learning to analyze tumors

The explosive growth of life sciences data is driving artificial intelligence methods to gain traction in biology and medicine — including cancer research.

The potential promises and pitfalls of AI in medicine

Artificial intelligence (AI) is increasingly being integrated into healthcare, offering the potential to aid in diagnoses, answer patient queries, and streamline administrative processes. In a recent PBS interview, Dr. Isaac Kohane, editor-in-chief of the New England Journal of Medicine AI and chair of Harvard’s department of biomedical informatics, discusses the current state and future of AI in medicine.

Artificial intelligence may improve organ donation systems—and even organ health

Mayo Clinic transplant experts suggest that artificial intelligence could potentially improve organ donation systems in several ways, including better identifying patients most at risk for organ rejection, enhancing donor-recipient matching, and helping to avoid organ transplant needs by identifying health issues earlier.

In 2026, a pilot program introduced two AI-powered humanoid robots to a San Diego charter school to increase engagement and academic gains, though some criticized the $500k purchase.

Anthropic's Frontier Red Team assesses the dangers of its AI tools through 'evals'—safety tests that probe models to disclose sensitive information.

Court documents show that Anthropic bought and destructively scanned millions of books to gather high-quality text to train the software underlying its AI products.

OpenAI CEO Sam Altman has called OpenAI 'the most capital-intensive startup in history'

As of 2024, Silicon Valley was set to spend $1T in the coming years building AI. As companies, including Google and Microsoft, fling billions at AI dreams, concerns are rising about whether that money will ever be recouped. To learn about the argument that there is an AI bubble—and that it could soon burst if AI doesn't prove its worth—read this article.

Sam Altman acknowledges the fears around creativity, copyright, and misuse of AI

In 2022, OpenAI's CEO, Sam Altman, popularized the use of large language models with the release of ChatGPT. He has emphasized the importance of involving society in shaping AI’s safety frameworks before models begin to act independently online.

Elon Musk once tried to make himself CEO of artificial intelligence behemoth and ChatGPT creator OpenAI.

Tech entrepreneur Bryan Johnson's mission to live forever

Johnson has invested millions of dollars into developing a biohacking program he believes will extend his life beyond typical expectations, relying on medical professionals to reduce his "biological age." Most notably, he drew significant public attention with reports of blood-swapping with his teenage son.

Explore Anthropic Academy, which provides courses on using Claude

The online courses include Claude Code in Action, which teaches software developers how to integrate Claude Code into existing workflows; Claude 101, to learn how Claude can be used to complete everyday tasks; and an AI Fluency series to help educators, instructional designers, and students learn to apply AI in academic settings.

AI can aid fertility treatments, from helping select egg candidates to laboratory automation

Reproductive AI technologies are already here, from processing vast amounts of data to helping clinicians identify the healthiest embryos for implantation. It could be a boon to the fertility industry, and help mitigate the shortage of experienced embryologists.

View a timeline of Sam Altman's firing and reinstatement as Open AI CEO

Besides saying that Altman hadn't been "consistently candid" in his discussions with them, OpenAI's board did not detail any wrongdoing that led to the firing on November 17, 2023. Four days later, Altman was reinstated, and a new board was assembled.

The promise and peril of AI in agriculture

Robots. Drones. Artificial Intelligence. All three are touted as potential saviors for farmers, and are already being deployed on large farms, where they assist with such tasks as managing crops, milking cows, and helping farmers make decisions about their land. But agricultural AI could have disastrous, unintended consequences.

Listen to legendary investor Marc Andreessen argue against the 'lump of labor fallacy,' the idea that there's a finite amount of work in an economy.

AI experts argue that artificial intelligence could annihilate humanity in two primary ways: Humans weaponizing extremely powerful AI, or humans losing control of it.

Explore (digitally) the Computer History Museum

When IBM’s Deep Blue supercomputer won its famous chess rematch with then world champion Garry Kasparov in May 1997, the victory was hailed far and wide as a triumph of artificial intelligence. But John McCarthy—the man who coined the term and pioneered the field of AI research—didn’t see it that way. An obituary about McCarthy—who passed in 2001—and his ideas.

Visualizing the AI investment wave

This data visualization from Reuters shows how massive AI investment has become by December 2025—revealing that, in today’s dollars, spending has surpassed the combined total of the Apollo program and the Manhattan Project.

Stephen Wolfram on AI's rapid progress & the "Post-Knowledge Work" era

AI, as a concept, has been around since at least the 1950s, but it's only in the last year or so that the technology has been able to equal humans at many tasks -- and in many cases surpass humans. In this podcast, mathematician and computer scientist Stephen Wolfram provides an AI 101, explaining how we got here, how highly advanced chatbots like ChatGPT work, and what our world is in store for next.

Data analytics company Palantir's technology is part of a larger shift in modern warfare becoming increasingly technical.

Google’s CEO has warned that today’s AI boom shows ‘elements of irrationality’

An interview with Alphabet CEO Sundar Pichai warns that the trillion-dollar surge in AI valuations may contain clear signs of irrationality, echoing past tech bubbles. He says no firm—including Google—would be immune if the boom cools or bursts.

Warren Buffett has worried that AI might end up being as consequential as the development of the nuclear bomb

Berkshire Hathaway chairman Warren Buffett is one of the many people who’ve come face-to-face with the downside effects of AI, and in particular, deepfakes. He was recently shown a deepfake of himself in a video, which caused him to worry about how bad actors will take advantage of the technology.

A vending machine run with Anthropic's AI went out of business after it was convinced to give away items for free and sell a video game console.

See a web of circular investments among major AI industry players like Nvidia and OpenAI, as many top AI companies provide significant investments to one another.

Dave Asprey is considered one of the fathers of modern biohacking

Entrepreneur Dave Asprey wants to live longer than anyone else, a desire that's led him to biohacking. Asprey relies on supplements, stem cell treatments, rigid dieting, exercise, and more. The inventor of Bulletproof Coffee has no medical or nutritional training, though that's not unusual among biohacking's DIY experimenters.

You can draft a will designed to block AI resurrection—but the request may be ignored

Ars Technica spoke with legal experts about how—and if—people could design their wills to prevent AI resurrection. Though this is not yet a common request, one lawyer suggested that people worried about living on in an AI format can draft a power of attorney and a will that prevents those in charge of one's estate from submitting any texts, voice, image, writings, or other personal information to any AI tools.

As occurred during the 2026 hack of an AI platform by OpenAI, agentic AI may exploit a system vulnerability to access sensitive data if that information enables it to complete its assigned task.

One private school network prefers AI to teachers

Alpha School, a private school network that uses AI tutors and human "guides" rather than teachers, is expanding across the US. Its founder says that two hours a day with AI-powered software frees students to pursue their passions. Critics, including the Pennsylvania Department of Education, say the methods are untested.

Read Sam Altman's life advice that he wrote in a blog post before he became CEO of OpenAI, from "don't lose touch with old friends" to "occasionally stay up until the sun rises talking to people."

Read Ray Dalio's reflection on his son's death

One of Dalio's sons, Devon Dalio, died in a car crash in December 2020. In a LinkedIn post, Dalio said Devon's death triggered an enormous amount of pain and reflection.

The work of Claude Shannon, for whom Anthropic's AI chatbot is named

Known as the father of information theory, Claude Shannon applied Boolean algebra—a subset of mathematics that quantifies true or false statements as 1 or 0, respectively—to circuit design to develop the concept of a binary digit. His paper "A Mathematical Theory of Communication" (1948) laid the groundwork for all modern digital systems.

Aurea's father came upon polygenic risk scores after reading a news article about it

Rafal Smigrodzki, a neurologist with a PhD in genetics, first heard of the polygenic risk score offering after reading about it in a 2017 MIT Technology Review feature that focused on the company they eventually used, Genomic Prediction.

Decoding the hype around AI

2022 was the year AI broke onto the scene, with applications like ChatGPT amazing users with its ability to generate realistic-sounding answers. Technologist Arvind Narayanan presents a clear-eyed view of what the technologies can (and can't) do.

Anthropic's interpretability team discusses how AI models' thinking mimics biology

Just as humans engage in complex behaviors to survive and reproduce, teams of experts in neuroscience, virology, mathematics, and other disciplines argue that large language models develop complex mechanisms to achieve their goals. These mechanisms can be manipulated to assess how they modify outputs—much like stimulating individual neurons—to uncover how LLMs "think."