Tattoos, explained

The immune system fights tattoos

Our skin is a fascinating organ that wants nothing more than to protect our bodies from the outside world. Tattoos penetrate that protective wall to inject ink directly into the sensitive, immunologically rich layer of skin known as the dermis.

Harvard and MIT researchers are developing life-saving tattoos

Tattoos aren’t just a fashion statement. Scientists are trying to find life-saving applications for them. Harvard and MIT researchers are developing tattoo inks that react to body chemicals, alerting diabetics to blood sugar fluctuations or athletes to dehydration. Someday, patients may observe their body chemistry with tattoos that change colors.

'Tattoo' comes from a Polynesian word that means 'to strike'

“Tatatau” roughly translates to “strike,” a reference to the ancient process, which involved tapping ink into the skin with sharpened objects, like the bronze implements used circa 1450 BCE in Egypt, below.

The body can remove tattoos after they are broken down by laser

Tattoos place blobs of ink below the surface layers of the skin in packets too large for white blood cells to clear out. By breaking the ink into smaller pieces, they can be processed by the immune system, which is responsible for removing foreign matter.

Technological breakthroughs are spurring innovations in the industry

What if you could see your tattoos before they’re embedded in your skin? Or take a virtual visit into a local studio to work out your nerves over a first tattoo? The industry is anticipating some big technological changes, from 3D designs to sci-fi upgrades to more precise tattoo guns.

Tattoo removal breaks apart ink particles

Tattoos place ink below the skin's surface layers in packets too large for white blood cells to clear out. By breaking the ink into smaller pieces, the immune system, which is responsible for removing foreign matter, can process them.

How 'the Iceman' got his tattoos remains a mystery

Ötzi the Iceman, discovered in 1991, is one of the oldest human mummies ever found—and his 61 tattoos remain a mystery. This explainer looks at how researchers believe the tattoos were made, what their placement suggests about ancient medicine and culture, and why we’re still piecing together their true purpose today.

Tattoos were once used to identify status

Around 450 BCE, Scythians inhabiting what is now southern Siberia were recorded as wearing tattoos of swirling mythical beasts to signify nobility. At the same time, tattoos have identified lower-status and enslaved people.

Tattoos are made by injecting pigments into the skin

Tattoo ink is injected under the skin, which can leave the body open to infections and allergic reactions. While many tattoo artists are licensed professionals who follow sanitary guidelines, that’s not always the case.

The first tattoo gun was based on an electric pen invented by Thomas Edison.

'Magic ink' is redefining the tattoo

One University of Colorado professor has developed an ink that can be "turned on" with exposure to UV light, and "turned off" with sunlight. While the ink could help those who want to hide their body art from family members or coworkers, there are potential uses for medical procedures.

Watch the engineering challenges overcome in turning a 3D printer into a tattoo machine

The DIY project required reprogramming the printer to operate on a curved, 2D surface rather than making flat layers in 3D, editing replacement firmware to bypass temperature safety checks, and developing a rapid system to stop the tattoo in case of an emergency. The final product printed "LEG" on a volunteer's leg.

'Skin stitching' is an ancient tattoo method that's made a comeback

In the slow method, artists use needles to puncture the skin. Then, pigmented thread is drawn through the punctures to create the tattoo, resembling embroidery in the flesh. The method is experiencing a cultural revival within Canada’s First Nations communities.

There are stigmas attached to tattoos

Although tattoos are fairly common in the US, some taboos remain. A 2017 study in the Journal of Social Psychology found discrimination against tattoos is alive and well, and that even individuals with tattoos associate them with negative stereotypes.

Tattoos suppressed during colonization are experiencing a revival

A few decades ago, the distinct facial tattoos worn by Maori people were on the brink of disappearing. Then, Maori artists brought the cultural practice back into the spotlight. This TVNZ story follows one reporter’s mother as, at 59 years old, she receives tā moko from a Maori artist.

Around 32% of American adults have at least one tattoo

Tattoos have waxed and waned in popularity over the centuries, depending upon the social standing of their wearers. Throughout US history, they were often considered taboo. However, growing acceptance of tattoos means they’re more visible in the public eye.

The world’s oldest tattoos belong to 'Iceman' Ötzi

Ötzi is the corpse of "the Iceman" found in the Alps along the Italian and Austrian border in 1991. His mummified body was covered with lines and crosses along the “hard-working” areas of his body, signifying their potential application for therapeutic pain management.

Sailor tattoos represent naval milestones

Sailors often come home with mermaids or turtles adorning their bodies. But what does it mean to have permanent images of propellers on your bum, British galleons with soaring tiers of sails on your chest, or a bicep portrait of the Roman god Neptune? Those tattoos represent meaningful naval milestones.

Removal of different color tattoo inks may require multiple lasers

Light needs to be absorbed by ink particles to break them down into small enough pieces for the immune system to eliminate. Color ink reflects, rather than absorbs, lasers of the same color, while black ink absorbs all colored lasers.

Laser procedures have made tattoo removal much more common

An increasing number of Americans, including high-profile celebrities, get tattoos removed because laser removal has become more advanced and cost-effective. The tattoo industry is adjusting to this mainstream trend.

Yakuza gangsters' tattoos often portrayed moments from their lives

Although tattoos have been worn in Japan for centuries, no single group is more famous for their elaborate, full-body tattoos—featuring traditional Japanese art—than Yakuza gangsters. The criminal organization does not use tattoos to mark their association, though. Instead, the scenes are intensely personal.

World Cup athletes use tattoos to convey aspects of their identity—including details of their faith, family, and accomplishments—in the otherwise tightly regulated arena of professional sports.

Tattoo inks are largely unregulated by the FDA

With hundreds of ink manufacturers, all unregulated by the FDA, it’s hard to determine the exact ingredients in tattoo inks. Some pigments may contain carcinogenic chemicals, such as heavy metals and aromatic hydrocarbons, or even bacterial contaminants. Red ink often causes allergic reactions and may even contain lead or mercury.

An interactive dive into the immune system

Our bodies are equipped with an incredible system able to fight off invasive pathogens to protect us from illness. The complicated system includes lymph nodes, the spleen, bone marrow, and even the tonsils. But this same system can turn against itself, a condition known as autoimmune disorders. Follow along with this thorough, engaging explainer on the human body's defense system.

Women in WWII used tattoos to avoid capture

During World War II, Japanese soldiers kidnapped women from Southeast Asian countries and forced them into sexual slavery. But they hesitated to capture married women, a fact that women from the island of Timor exploited, painstakingly poking tattoos onto their bodies that marked them as married women.

In the 1950s, Alan Turing developed a mathematical model to explain why animals have stripes, spots, and other patterns based on differences in how quickly two interacting chemicals spread throughout a developing organism.

Most advanced touch screens rely on electrical charge in your skin

Capacitive touch screens store electrical charges in an electrostatic grid of tiny wires. When we touch the screen a tiny electrical charge is transferred from the screen to the finger to complete a circuit (since skin has positive and negative charges). This connection creates a voltage drop on that point of the screen. Cloth, however, doesn't conduct electricity, which is why humans can't wear thick gloves and operate their smartphones.

The history of blood, as told by a hematologist

Since ancient times, blood has been seen as a semi-magical substance. Alchemists theorized it was a mixture of the four elements. Others proposed it was one of four bodily fluids whose balance dictated health. This 2019 essay by a hematologist reviews blood's reputation across cultures and centuries.

The strange endurance of consuming blood for health

Blood's importance to humanity is best summarized this way: without it, we die. This importance naturally begets assumptions about its medicinal properties, many of which appear accessible through drinking or eating the fluid connective tissue. This article details the history of blood drinking, from ancient Roman gladiators to modern-day sanguinarians.

The history of ghosts, explained

The afterlife has perplexed humans across different periods, cultures, and belief systems. The desire to understand what comes next is often explored through the telling of ghost stories. Learn more about the spooky phenomena here.

Rune Elmqvist forwent practicing medicine to invent the first inkjet printer

The Mingograph recorded real-time physiological signals from a patient's electrocardiogram, helping doctors diagnose heart and brain conditions. Eight years later, in 1958, Elmqvist worked with cardiac surgeon Åke Senning to develop the first fully implantable pacemaker.

Laser-etched electric charges guide toner during laser printing

When sending a print job, the file data generates an image that a laser maps positively charged regions onto a drum separately for each color toner. Once the negatively charged toner is applied where it was electrically attracted, heat and pressure fuse it onto the paper.

Artificial goose bumps could theoretically be used for information storage

Inspired by how fine hairs stand on the skin with goose bumps, researchers have recently created artificial skin that raises artificial goose bumps when exposed to a laser. This type of precise, localized, and controllable system could potentially fuel later development of programmable machines that could be used for information storage.

The history of skull modification

The ancient Maya people sometimes modified their skulls to appear more conical. Body modification has been a human pastime for literal ages, from piercings to bindings and everything in between. Modifying one's skull shape may have been a way to symbolize status, beauty, belonging, or belief. The health impacts of such practices are still debated. This article explores the history and health impacts of skull modification, also known as artificial cranial deformation.

What is the immune system? A quick 101

Your body’s immune system is designed to protect you from infection. Find out more about how the immune system works with this quick overview and set of diagrams.

Hacking the body for a future that didn't happen

Journalist Adi Robertson experimented with one of the most accessible biohacks: magnets. Having a tiny magnet in their right ring finger meant they could sense magnetic fields, attract small metal objects, and more. But magnets weaken over time, eroding this new sense. Such implants do more than offer a new way of interacting with the world, they also pose new complications, such as the inability to get an MRI.

An essay exploring how living day-to-day with a brain implant helps restore a sense of identity

Companies like Neuralink are experimenting with volunteers who have lost control over their bodies. Many of the program's participants claim the most significant benefit from the tool is the ability to perform simple, mundane tasks, such as playing video games or shaking hands, rather than more obvious milestones like walking or eating. This essay explores what it's like, day to day, to use a brain implant.

Seven things you might not know about blood

The red stuff currently pumping throughout your body is a type of connective tissue that is both a solid and a liquid. The liquid portion—plasma—acts as a carrier for the solid portion, which includes blood cells and their biological brethren. Your body is constantly refreshing its supply of blood, creating new cells to replace those that have expired or died. This article overviews some lesser-known facts about blood (and why it's not always red).

The role of textiles in South Asian art

Textiles play an essential role in the religious traditions of the Indian subcontinent, acting as portable shrines that can relay important allegories and depict spiritual iconography. This primer from Smarthistory breaks down how imagery is used on these textiles and helpfully provides high-quality images, allowing you to witness their beauty for yourself.

What is immunotherapy and how does it work?

Immunotherapy is a type of treatment that harnesses the body's immune system to combat cancer. This video explainer from the American Cancer Society discusses various types of immunotherapies and their roles in targeting cancer cells. Still a new and quickly evoliving field, immunotherapy represents a significant advancement in cancer treatment and offers new options for patients.

Fiber lasers used for metal engravings can’t burn your skin

These devices use diodes and mirrors to create pulses of light that vaporize metal in billionths of a second, though at wavelengths that cannot react with organic material. Pulse width, power, and speed adjustments can produce white, black, and even colored patterns through controlled heat reactions.

A history of belly buttons, from dinosaurs to modern dogs

Could dinosaurs have had belly buttons, just like you and me? Some researchers believe they've found evidence the ancient reptiles had the cute scar, a common feature among placental mammals (but which is also found in many more kinds of animals). Dive into their peculiar findings with this fascinating video.

Autoimmunity is when the body attacks itself, causing inflammation

Inflammation is the body's way of healing itself, and acute inflammation saves our lives when we have injuries or infections. It increases blood flow to the affected areas to bring immune cells to fight off invaders. This often results in short-term swelling, redness, and pain.

How 3D printing inside cells paves the way for microscopic machines

In 2026, scientists in Slovenia developed a method to 3D print a small elephant, several microscopic geometric objects, and barcodes for cell labeling within living human cells, which continued to grow and divide thereafter. The experiment opens the door to fabricating devices within cells to study and manipulate cellular functions.

Blood has evolved many times over hundreds of millions of years, resulting in different blood colors and compositions—and there are even some organisms that don't need blood at all.

What are 'antibodies'? Read this quick overview

Antibodies are protective proteins produced by your immune system. They attach to antigens (foreign substances) and remove them from your body. Understand this important element of the immune system with this quick overview.

Cells can last in the human body from days to a person's entire life

Despite claims that a person's body replaces itself every seven to 10 years, the rate at which cells die and are replaced varies by cell type. Gastrointestinal cells that line the digestive tract and stomach last only a few days, while some heart muscle cells and most neurons are around from birth until death.

These cells 'taste' danger, trigger immune responses

Taste receptor-coated tuft cells are found throughout the body, where they communicate with and take part in a growing list of biological processes. In the intestines, these taste receptor-studded cells can sense byproducts of parasite metabolisms. This causes the taste receptors to release chemicals that alert the immune system, order nearby goblet cells to produce mucus, and trigger muscle contractions in attempts to launch the parasites from the intestines.

Researchers have investigated the benefits of extreme pain rituals, exploring how and why we engage in these events when humans generally naturally avoid pain and perceive it as a negative experience.

Breaking down the different types of vaccine technologies

There are several different types of vaccines. Each type is designed to teach your immune system how to fight off germs—and the serious diseases they cause. This short overview breaks down the differences between the types.