A 'paranormal activity' unit at the University of Virginia studies challenges to mainstream scientific ideas about human consciousness.

The University of Virginia has the nation's most established near-death studies division, but institutions including the University of Southampton, the University of Connecticut, and the University of North Texas have also explored the field.

A leading expert on near-death experiences, psychiatrist Dr. Bruce Greyson, says that during his decades of research on this topic, this area of research has become far more mainstream and accepted as a rigorous area of inquiry.

Accounts of near-death experiences share similarities with hallucinogens, with reports of mystical-like states of consciousness across both contexts.

A radiation oncologist has studied near-death experience reports for over 25 years and compiled around 4,000 accounts in the hopes of finding more patterns that would reveal insights about consciousness and humans' final moments before or around death.

Studies of psychedelic use may help shed light on the nature of consciousness

The nature of consciousness—what it is, where it comes from, and how it manifests as moment-to-moment experience—remains under debate by scientists. Recent studies show psychedelics were found to boost low-frequency brain signals known as delta waves, a behavior also seen during dream states.

There's a new (contested) physiological explanation for near-death experiences based on analysis of the brains of resuscitated coma and cardiac arrest patients.

The body's response to cardiac arrest has been linked to near-death experiences.

Brain activity sometimes goes into overdrive around the point of death according to researchers' recent analysis of patients' brains before and after they were taken off their ventilators.

Some scientists argue NDEs are constructed by the brain, not actually experienced

Despite the powerful memories associated with NDEs, scientists question the idea that the experiences prove consciousness endures after death, opting instead to find physiological explanations for common reports of out-of-body experiences, euphoric and lucid thinking, and more.

Meet the Dutch cardiologist who believes consciousness can exist outside the body

Dutch cardiologist Dr. Pim van Lommel conducted one of the largest studies of near-death experiences following cardiac arrest, publishing the results in the prestigous journel The Lancet. He later went on to argue (to significant criticism from peers) that his findings suggest consciousness can exist outside the body.

The main criticism of a recent neurophysiological explanation for near-death experiences is that these events are too complex to be explained as a neurochemical response to an oxygen-deprived brain.

Near-death experiences can be reminiscent of religious visions, yet people across different faiths as well as those with no declared religion have reported them.

A near-death experience is a phenomenon experienced by roughly 5% to 23% of the population, and typically occurs after a traumatic physical event or a brief clinical death.

Scientists are studying dying patients' brain activity in the final moments of life

In the final moments of life there are distinctive bursts of coordinated neural activity. Researchers are interested in parsing that data to better understand the dying process and also exploring how this data relates to our understanding of consciousness.

NDEs typically change people's outlooks drastically and can prompt depression

The phenomena are regularly categorized as hallucinations, but some specialists are interested in their psychological nuances. Many survivors report feeling less anxiety about death, though some surveys show the experiences can increase physiological sensitivities.

The neurobiology of meaningfulness: the benefits of psychedelics

Psychedelics produce powerful emotions in its users, including a profound sense of meaningfulness. The philosopher William James called this sense "noetic" in the late 19th century, but for decades researchers avoided studying the effects of such drugs on the brain. However, the recent resurgence in psychedelic research has heightened interest in the relationship between this noetic sense resulting from the therapeutic use of drugs. Learn what researchers have found out here.

'1440 Explores' Episode 3: Why We See Ghosts and What Isn't There

Every culture has them—restless spirits, haunted houses, things that go bump in the night. But why do we believe in ghosts? Psychologist and skeptic Dr. Chris French joins host Sony Kassam to explore the science behind the supernatural, from sleep paralysis and hallucinations to the brain's pattern-making instincts. Together, they uncover why our minds see meaning—and sometimes ghosts—where none exist, and what that reveals about fear, memory, and our need to believe in something beyond the grave.

How can octopuses and MDMA help scientists understand the human brain?

Research shows that psychedelics may induce something called "critical periods" in the adult brain, which can make our brains more open to learning and changing, like they once were back in early childhood. Psychedelics similarly change how social creatures like octopuses behave, which demonstrates that these animals could help us better understand our own neurobiology.

Could this pseudo-psychedelic VR experience decrease symptoms of depression?

Researchers report that virtual reality and psychedelics may be leave users with similar insights and therapeutic benefits. Try out this free psychedelic virtual reality experience to see if this holds true for you. According to the program’s creators, a study into the efficacy of this 45-minute experience indicates it may help alleviate symptoms of mild to moderate depression.

Psychiatrist Bruce Greyson created a scale to identify and rate NDEs

Researcher Bruce Greyson is one of the world’s leading experts on near-death experiences. This article explores what the field of NDE research has learned over the last five decades, discusses the difficulties of studying such a controversial topic, and outlines what we’ve ruled out as the cause of these events.

What can psychedelics teach us about dying?

Psychedelics have made their way into the world of licensed mental healthcare, and the drugs have been proven to help people process and lessen anxiety and depression. What does this mean for people with terminal illnesses who are afraid of death?

Four in 10 CPR patients report consciousness not captured by standard measures.

Psychedelic drugs are having a scientific renaissance

After decades of repression, psychedelic research is making a resurgence. Hear from a host of experts in this 20-minute video on what that could mean for the future of mental health. The current science on psychedelics believes LSD can cause a particular brain network to quiet or deactivate.

The science behind ghosts, explored

Every culture has them—restless spirits, haunted houses, things that go bump in the night. But why do we believe in ghosts? Psychologist and skeptic Dr. Chris French joins host Sony Kassam to explore the science behind the supernatural, from sleep paralysis and hallucinations to the brain’s pattern-making instincts.

How psychedelics can potentially reinvent learning

Critical periods, discovered in the early 20th century, describe a period when someone is incredibly sensitive to their environment, and any information learned can stick with them for life. Some researchers argue these states can be "reopened" via psychedelics, which put the mind into a malleable state that can potentially be used to treat conditions ranging from lazy eyes to PTSD.

Some founders of quantum mechanics thought consciousness could influence phenomena

Since quantum systems exist as a superposition of states before producing a definitive outcome, some quantum pioneers wondered if the act of conscious observation was what collapsed the wave function of possibilities into one state.

The debate on why humans are conscious—and what that means

Understanding what consciousness is, and why and how it evolved, is perhaps the greatest mystery known to science. Watch interviews with the world's leading experts on what it is and whether we'll ever know.

Psychedelic side effects, including worsening mental health for some patients, give pause

This article explores whether the therapeutic potential of psychedelic drug use is really as good as current research suggests. Scientists are exploring its applications for conditions ranging from the existential crisis that can accompany terminal diagnoses to chronic mental health conditions, including anxiety and PTSD.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

Listen to an avowed rationalist discuss his frightening near-death experience visions from 2020 and how it changed his life outlook.

Terminal lucidity is the phenomenon of sudden, heightened mental clarity when on the verge of death

The "Let's Talk Near Death" podcast explores phenomena around the end of life, inviting guests to recount their own experiences. This episode focuses on the phenomenon known as "terminal lucidity," where patients experience clarity, vivid memory recall, and more, typically following a heart attack, stroke, or other trauma.

What happens in a dying brain?

Near-death experiences usually happen during death or on the border of life and death when a person isn't understood to be conscious. This article details the science of what's going on with the brain during NDEs.

Oregon voters in 2020 greenlit adult use of psilocybin—the active ingredient in magic mushrooms—in state-licensed centers, and a 2026 analysis indicates the program has good safety and satisfaction data.

Watch veterans experience psilocybin at a Mexican clinic and discuss the aftermath

This "60 Minutes" episode from 2025 follows nine veterans attending a week-long psychedelic retreat to treat their PTSD. Most of the vets say the experience at the Mexican clinic was life-changing. But results were mixed: One veteran reported he was scared and that the experience worsened his mental health overall.

Researchers say that the horror genre offers opportunities to safely experiment with fear.

This is the human brain on the world's strongest psychedelic

Within seconds of inhaling a high dose of vaporized synthetic 5-MeO-DMT—a lab-produced substance that otherwise is naturally derived from the glands of the Colorado River toad—it induced slow brain waves. Such waves are typically associated with unconsciousness due to a coma or anesthesia, perhaps explaining why users describe feeling like everything falls away. The compound is currently in clinical trials for treating depression.

An LSD scientist's role in a US mind control project

Within a decade of LSD's discovery, the US government had launched a secret initiative involving hypnosis and hallucinogens. LSD researcher Louis Jolyon West conducted experiments for the CIA's MKUltra project, which focused on the potential of mind control. He later took part in a criminal trial that hinged on testimony whose sourcing was seemingly inspired by MKUltra experiments. This article explores light shed by West's personal archive.

Humans experience the world subjectively. What does that mean for scientific research?

When you close your eyes, do you see static or colorful patterns or an "intrinsic grey" known as Eigengrau in German? This variation of our internal experiences is just the tip of the iceberg, one that scientists are increasingly studying and...

Two scientists argue consciousness evolved through 'unlimited associative learning,' the ability to learn almost any new pattern during a lifetime.

The commercial and therapeutic potential of psychedelics

A 2006 study into the potential therapeutic benefits of psychedelics sparked a renewed interest in the field of psychedelic research, a development that has cascaded into commercialized ventures and experiences. This article details how growing research into the psychological benefits of psychedelics is matched by the rise of anecdotal reports, book deals, businesses, and corporate claims seeking to capitalize on psychedelic potential.

The history of ghosts, explained

The afterlife has perplexed humans across different periods, cultures, and belief systems. The desire to understand what comes next is often explored through the telling of ghost stories. Learn more about the spooky phenomena here.

Afterlife traditions help some humans process death

Watch this video discussing concepts of the afterlife presented through an anthropological lens about one family's experience and traditions passed down from one generation to another.

Scientists are experimenting with ways to probe the multiverse theory

Researchers are simulating vacuum bubbles—the theorized starting points of universes—using quantum computers, digital models, and exotic lab setups to study how they form, expand, and possibly collide. One experiment aims to "blow" artificial universe-like bubbles inside ultra-cold quantum gases, potentially capturing real-time glimpses of cosmic birth processes in a lab.

Near-death experiences have been reported across cultures for millennia.

The dreaming brain, as understood by scientists

Technology has advanced to where the seemingly separate fields of psychology and neuroscience are asking the same questions about dreams, such as whether they're more closely related to perception or visualization. Some field-intersecting findings include research that shows people with impaired face perception don't dream of faces, those with brain legion-related cognition difficulties deal with similar issues in dreams, and children's dreams change in parallel to their cognitive development.

How science explains déjà vu

Take a fun look at the science explaining the odd experience of déjà vu, which some theories suggest is actually a sign of a healthy brain.

Psychedelics set off a flurry of brain activity that may permanently alter it

The brain seems to experience a sharp increase in communication between areas that generally don't interact. New research suggests a thin, sheet-like gray matter structure tucked deep within the brain, between the insular cortex and striatum, may be the key to this change. The area is centrally located and home to many of the receptors that psychedelics target, potentially rewiring the brain and rewriting thought patterns.

The oldest medical report of a near-death experience dates to around 1740.

Why 'spacing out' or dissociating may help reduce trauma awareness

Dissociation may have developed as a defense mechanism in the brain to help navigate intense emotional or physical situations by providing out-of-body experiences that put distance between the mind and the environment. However, in about 1.1% and 1.5% percent of the general population, a severe form of this separation can produce alternate identities, or alters.

Thanatology is the study of death and dying.