Billions of flies are being dropped from the sky

Mosquitoes are the world's deadliest animal, but gene drives could kill them.

Explore inside a mosquito factory where millions of mosquitoes are bred weekly

In Medellin, Colombia, scientists are infecting Aedes aegypti mosquitoes with Wolbachia, a bacterium that wouldn't otherwise infect the species, but does block its ability to transmit dengue, Zika, yellow fever, and chikungunya. In the wild, infected mosquitoes would breed with wild mosquitoes, pass down Wolbachia, and thus reduce disease transmission.

Malaria mosquitoes in a lab were wiped out using CRISPR

Scientists at Imperial College London disabled a gene in female Anopheles gambiae mosquitoes to make them infertile and propagated the infertility mutation at unnaturally high rates using a gene drive. The entire population collapsed within a dozen generations, showing promise for subsequent with mosquitoes in mimicked tropical environments.

Wolbachia is also being used to slash mosquito numbers

The naturally occurring bacterium does not naturally infect Aedes aegypti mosquitoes, but communities in locations including California and Texas have released male mosquitoes infected with Wolbachia and reported a significant drop in subsequent mosquitoes: When infected males mate with uninfected wild females, the eggs don't hatch.

What if we killed every mosquito on Earth?

Mosquitoes aren't just annoying, they're deadly. they're also responsible for an estimated 725,000 deaths worldwide, every year. Would it be so bad if we found a way to wipe them out completely? Real scientists have gamed out this hypothetical scenario, concluding it actually wouldn't be that bad. This five-minute video breaks down one way this could happen.

Examining the potential of the emerging field of insect-based bioremediation

Also known as entomoremediation, the novel approach uses larvae and adult insects, including their gut microbiomes and associated enzymes, to extract or degrade pollutants. As of 2025, research has shown that black soldier flies can degrade a wide range of antibiotics, highlighting their potential for bioremediating antibiotic-contaminated organic waste.

Researchers are breeding genetically modified mosquitoes to be malaria-resistant.

Sleep deprivation leads to the buildup of dangerous molecules in the gut.

Genetic engineering mice is one idea to reduce Lyme disease transmission

Wild white-footed mice are the main carriers of Lyme. A research team is hoping to genetically engineer mice, using CRISPR, to make the animals immune to Lyme. They're proposing a field trial where they would insert a gene with an antibody to Lyme infection to break the disease transmission cycle on a private island and then try it in Nantucket if that goes well. Simply killing the mice isn't an option because it would upend food webs. Unlike traditional vaccines, this "heritable immunization" would pass from one generation of mice to the next.

Wolbachia: the bacteria that could eliminate dengue fever

Dengue fever, transmitted by mosquitoes, kills more people annually than all types of natural disasters combined. However, mosquitoes that host Wolbachia bacterium have their ability to transmit the virus naturally suppressed, offering a route to eliminating nearly 25,000 deaths annually.

Wolbachia is a naturally occurring bacterium being employed to fight dengue

Scientists are fighting dengue spread in a roundabout way: injecting bacteria into Aedes aegypti mosquito eggs, which blocks the dengue virus from replicating in the tissue of mosquitoes. Researchers hope the bacterium will be passed to future generations, inoculating them against dengue. Wolbachia is also being investigated to combat other mosquito-borne diseases.

From 1970 to 2017, invasive species have caused $1.28T in damage globally

The costliest species were the Asian tiger and yellow fever mosquitoes ($149B), which arrived in the US from Asia and sub-Saharan Africa, respectively. The bulk of their damage came from their transmission of diseases such as Zika, chikungunya, and dengue. (Some readers may experience a paywall.)

Fruit fly sperm are gigantic—about 40 times larger than human sperm, according to scientific research published in June 2026.

Visual deep dive into the collapse of insects

The most diverse group of organisms on the planet are in trouble, with recent research suggesting insect populations are declining at an unprecedented rate. Explore this visual interactive on the issue from Reuters Graphics.

Watch Cordyceps, a parasitic fungus, turn an ant into a ‘zombie’

This National Geographic TV clip shows how a parasitic Cordyceps species—sometimes colloquially called the “zombie ant fungus”—controls an ant’s behavior and kills its host. The fungus can rapidly wipe out entire insect colonies.

Some mosquitoes are key pollinators—and eat disease-carrying mosquitoes.

Using mosquitoes to vaccinate bats could curb the spread of deadly diseases.

Spiders may manipulate captured male fireflies into mimicking female mating signals

Rather than killing a male firefly captured in its web, the Araneus ventricosus spider bites into it, which researchers believe injects a venom that disrupts normal flashing behavior and produces a form of mimicry to attract additional males. (Some readers may experience a paywall.)

Mosquitoes top the ranking of the world's deadliest animals.

How a worm helped give the southern US its reputation

"The germ of laziness" that blanketed the southern US for centuries with unshakable fatigue, brain fog, and distended bellies paired with emaciated frames was actually a worm. This parasitic worm lives in the gut, where it can stay up to five years, laying up to 10,000 eggs daily. Hundreds of millions of people worldwide continue to suffer from hookworm infections, often obtained by walking barefoot across infected soil.

An invasive, tree-killing beetle may threaten large swaths of Australia

A Curtin University study warns that large parts of Australia, including major cities and farming regions, could be highly vulnerable to the fast-spreading polyphagous shot hole borer, which releases a fungus that can starve trees of nutrients. The tiny insect has already caused severe damage across the Perth metropolitan area.

About one-third of the world's food supply depends on pollinators like bees, butterflies, and bats to transfer pollen between flowers, which use bright colors, scents, and nectar to attract them.

Butterfly populations have declined by 22% from 2000 to 2020

Research suggests that one in every five butterflies is lost due to pesticide use, habitat loss, and climate change. Playing a vital role in pollination, their declining populations threaten plant reproduction and the health of ecosystems.

Bedbug problems have been increasing, and some 2023 research suggests the tiny insects may be capable of spreading 'superbug' MRSA.

More than 2 billion people across the globe include bugs in their diets

Entomophagy is the practice of eating insects. It has been around for millennia. Bugs are nutritious and, in some places, considered a delicacy.

Mosquitoes drink a maximum of 0.01 milliliters of blood in a single meal.

'Sloth fever' is an emerging health threat, especially to pregnant women

This disease, caused by the Oropouche virus, is found in animals including sloths, primates, and birds. It primarily spreads through the bite of midges—insects commonly called "no-see-ums." It's endemic to the Amazon region, but US travelers are increasingly contracting it internationally.

Over 1,500 insect species pollinate plants in the UK

These insects—including bumblebees, moths, butterflies, and beetles—play a crucial role in the reproduction of flowering plants, also known as angiosperms. They do so by transferring pollen from the male reproductive organ—the anther—to the female one—the stigma—which enables the plant to produce fruit.

How we helped make Aedes aegypti mosquitoes such a problem

Mosquito genome sequencing data suggests that Aedes aegypti mosquitoes first started specializing on human blood around 5,000 years ago—when climates shifted and humans started domesticating plants in Africa and stored large amounts of water that may have attracted the bugs.

'Birds Aren't Real' parodies the way memes traffic conspiracy theories

Peter McIndoe claims the US government killed 12 billion birds only to replace them with drones. These statements have powered protests—and McIndoe's fictional campaign that highlights how conspiracies and their theorists are treated.

Some female fireflies mimic the signals of other species to lure in and eat them

The genus Photuris does not produce its own defensive pheromones to ward off predators, so it has developed mimicry to attract males of firefly species that do. Unsuspecting males are consumed after these chemicals—lucibufagins—are extracted.

Mosquito necroprinting uses an insect's mouthpart as the printer nozzle

Mosquitoes are abundant, and their nozzles are 32-100 times cheaper to harvest than to create from scratch out of metal or glass. By coating the organic nozzle to increase its strength, researchers are employing necroprinting to create tiny structures at better resolutions than commercial alternatives.

Mosquito saliva acts as an anticlotting agent

The bug's piercing mouthpart, the proboscis, is actually several tubes—one for sucking, one for spitting. But the chemicals in its spit actually help its blood meal to flow, combating its victim's ability to clot at the puncture site.

There are at least 6 fascinating examples of mind-controlling parasites

Parasitic organisms—including flatworms and barnacles, not just fungi—can modify animal behavior. They can give rise to dancing fish, pulsating snails, suicidal rats, and more. Though some of these pathogens can sicken humans, there is no strong evidence that any can control human behavior.

Scientists still don't know why DEET is such an effective bug repellent

This chemical, used to keep ticks, fleas, mosquitoes, and other nuisance bugs away, is used by an estimated one-third of the US population and has been available to consumers since 1957. Researchers theorize that multiple mechanisms may be at work to deter bugs, including perhaps masking or confusing bugs' olfactory receptors.

Bees are crucial for pollination and food security

When animals and insects pick up the pollen of flowers and spread it, they allow plants, including many food crops, to reproduce. The most common pollinator is the bee, but bees are at risk from pollution and pesticides.

Microplastics are entering human food chains through carrots, wheat, and other foodstuffs grown in farmlands fertilized by sewage sludge.

At any given time, there are an estimated 10 quintillion individual insects alive on Earth.

Fruit fly experiments helped identify genes responsible for major body development

The insects' fast life cycle and affordability have allowed geneticists to quickly identify which genes are responsible for limbs, eyes, and other body structures by inducing mutations. The same genes may be responsible for different parts of a species' body, such as limb-building genes being responsible for wing pigmentation in butterflies.

Mosquitoes stop flying at wind speeds equivalent to the swishing of a horse's tail.

The Burmese pythons in the Florida Everglades and the spotted lanternfly—native to Asia and now found throughout the US—are among the invasive species accidentally introduced and spread by humans.

How bedbugs have evolved immunity against pesticides

Bedbugs, once nearly eradicated in the United States due to the use of pesticides like DDT, have made a resurgence, with New York being declared the most bedbug-infested city. The primary reason for the return is the evolution of resistance in...

Vector-borne diseases kill more than 700,000 people globally each year—and are growing

The diseases with the greatest potential to spread widely aren't the ones that quickly kill human hosts. Instead, the best hosts or reservoirs for vector-borne diseases would be chronically ill over the long term, increasing the likelihood that the pathogen could be transmitted to others.

Cordyceps: the fungi that turn ants into zombies

The hit show (and video game) "Last of Us" was inspired partly by real-life species of fungi that have been known to turn ants into zombies. Spores of the Cordyceps fungi are capable of penetrating the exoskeletons of arthropods, after which they break into enzymes and proliferate within the body. The fungal cells then hack the ant's nervous system and trigger compulsive climbing.

Agricultural intensification has accelerated declines in pollinator populations

The practice of using farmland more frequently to increase its yield increases the number of residual pesticides and decreases botanical biodiversity. These processes tend to decrease carrying capacity for pollinators by eliminating food sources and nesting habitats.

How a scientist discovered West Nile is spread by birds

Listen to Tracey McNamara, former chief pathologist at the Bronx Zoo, detailing her surprising late 1990s discovery that established West Nile virus is spread by birds. Financing animal disease surveillance studies, she says, saves human lives and surveillance gaps may fuel missed opportunities to identify dangerous diseases before they jump between species.

Treating black fever can result in a complication that spreads the deadly disease

Black fever, a deadly parasitic disease second only to malaria, threatens more than 1 billion people across more than 83 countries. Also known as kala-azar or visceral leishmaniasis, the disease is caused by parasites that spread through sandfly...

Supertoxic rat poisons are wreaking havoc on unintended targets, including predator birds, mammals, amphibians, crustaceans, and insects.

Efficiency of commercial honeybees may exacerbate population declines in native bees

Commercial beekeepers are increasingly breeding honeybees on public lands, raising concerns among environmentalists that they’ll compete with and introduce new diseases to already threatened native pollinator populations. However, native species alone are often unable to meet the pollination levels required to meet necessary crop yields.

Metamorphosis evolved over millions of years as species that hatched as smaller versions of adults started exhibiting genetic mutations that differentiated juvenile and adult bodies.