Examining the potential of the emerging field of insect-based bioremediation

Why bacterial bioremediation may help counter the negative effects of past chemical solutions

Molecules such as DDT, a synthetic insecticide, and PFAS—"forever" chemicals used to make products resistant to heat, water, and grease—have historically been used across various industries but are now known to be harmful. Microbes that can convert some of these substances into nontoxic products, such as water and carbon dioxide, have already been identified, with ongoing research to find others.

An overview of bioremediation, which can help clean up oil spills, mining waste, and some plastics

The umbrella term refers to a variety of techniques that use organisms to remove harmful substances from an environment or break them down into nontoxic compounds. Because the availability of certain resources can limit the growth of these organisms and impair bioremediation efforts, nutrients such as fertilizers can be deployed to accelerate cleanup.

Learn how environmental conditions are optimized to increase bioremediation efficacy

Through biostimulation, Indigenous microbes are provided with moisture, nutrients, or oxygen to prevent their death and ensure optimal progression of their biochemical reactions. Bioaugmentation can introduce new microbial cultures to target specific compounds not natively found in the environment, while landfarming can spread or aerate contaminated soil to improve access to contaminants.

The risks of bioremediation, from intermediate products to ecological disruption

A step in the series of complex biochemical reactions involved in the implemented bioremediation process may produce dangerous molecules—sometimes more toxic than the initial pollutants—that require ongoing monitoring to ensure optimal conditions for processing these intermediates toward the eventual, safe outputs. Introducing non-native nutrients or species, including GMOs, may alter existing food webs and gene pools.

Comparing bioremediation with other treatment techniques, at three levels of complexity

Physical manipulation, such as collecting and moving contaminated material to a landfill, or chemical applications, which use strong, expensive substances and produce harmful byproducts, can be costly. While bioremediation leverages naturally occurring degradation processes that can be augmented without disrupting impacted ecosystems, these processes may be less effective in environments that bioremediation organisms are not adapted to.

The adaptations of metallophiles and how they can be harnessed for bioremediation

These extremophiles have adapted to biomes with very high concentrations of metals and toxic chemicals by developing mechanisms to isolate these substances within cellular compartments and break them down into less harmful forms with specialized proteins. They have the potential to support the decontamination of metal-rich wastewater and soil, as well as the extraction of rare-earth metals.

How the US Department of Energy facilitated bioremediation with emulsified soybean oil

At sites where soil and groundwater were identified as contaminated with volatile organic compounds, scientists and engineers at the Office of Legacy Management used microbes to safely clean them up without more invasive methods, such as pump-and-treat. Treatment zones created at one location by injecting oil to help microbes spread quickly.

View a breakdown of bioremediation strategies, divided into onsite and offsite options

Depending on the contamination's complexity, in situ—onsite—options may be preferred and can include supplying oxygen or nutrients into the existing soil to accelerate the microbial breakdown already present in the environment. Ex-situ methods instead displace contamination for treatment away from the environment and may be used for volatile chemicals that require isolation, though this displacement can also spread contaminants if spilled.

Learn about historical uses of bioremediation, the oldest cleanup method on Earth

Biochemical reactions that decompose complex molecules into simpler ones have occurred on Earth for as long as life has existed and have gradually transformed the planet into a celestial body that is increasingly habitable to greater biodiversity. Along the way, modern, human-made bioremediation techniques began to take shape in Santa Maria, California, in the 1960s.

How microbes limited the damage and helped clean up the Deepwater Horizon oil spill

A bloom estimated to contain about 100 sextillion microbial cells broke down much of the 4.1 million barrels of spilled crude oil into nontoxic compounds in what was one of the most significant bioremediations of a human-made disaster. The microbes involved acted similarly to the first patented genetically modified organism in US history: an oil-eating bacterium engineered in 1971.

Analyzing brownfield cleanup to explain why bioremediation aligns with environmental justice

This designation applies to sites contaminated by industrial or commercial activity and that are either underutilized or abandoned. Common in economically disadvantaged communities of color, brownfields pose risks to human health and can be costly to restore. Bioremediation can be a more affordable solution that creates in-demand employment pathways in environmental science, regenerative agriculture, and ecological restoration for community members.

More than 2 billion people across the globe include bugs in their diets

Entomophagy is the practice of eating insects. It has been around for millennia. Bugs are nutritious and, in some places, considered a delicacy.

A visualization of mycoremediation, where fungi extract toxic and radioactive pollutants from soil

As organisms such as mushrooms grow, they develop large networks of root-like structures called mycelium that spread underground and release enzymes that break down contaminants. By absorbing these chemicals, fungi limit the damage caused by these toxins and localize them within the organism for easier collection and disposal.

Watch students comically portray how plants can detoxify the environment

Through a series of processes that collectively make up phytoremediation, plants can take up pollutants from soil and water through their roots, then break them down, release them as less harmful gases, or store them within their cells. Any plants that sequester heavy metals or other toxins must be removed and managed after the environment is decontaminated.

Billions of flies are being dropped from the sky

The US is dropping billions of sterile flies to stop a deadly parasite. Screwworm maggots eat animals alive, so scientists are collapsing the population by ensuring females can’t reproduce.

Most plastics are not biodegradable because breaking their chemical bonds requires temperatures lethal to most microbes, and these organisms have not been exposed to plastic long enough to evolve the necessary enzymes.

Bedbug problems have been increasing, and some 2023 research suggests the tiny insects may be capable of spreading 'superbug' MRSA.

Wolbachia is a naturally occurring bacterium being employed to fight dengue

Scientists are fighting dengue spread in a roundabout way: injecting bacteria into Aedes aegypti mosquito eggs, which blocks the dengue virus from replicating in the tissue of mosquitoes. Researchers hope the bacterium will be passed to future generations, inoculating them against dengue. Wolbachia is also being investigated to combat other mosquito-borne diseases.

Researchers are breeding genetically modified mosquitoes to be malaria-resistant.

Microbial research suggests shifts in diverse populations may help an invasive species establish itself

In 1958, English ecologist Charles Elton suggested that diverse ecosystems should be more resistant to invasive species because gaining a foothold would be more challenging when resources are more thinly spread. However, in lab-grown microbial ecosystems with greater biodiversity, population volatility opened more ecological roles that invasive species could easily fill.

Scientists from the frontline discuss the future of antibiotics and superbugs

Superbugs are a very real problem, but researchers around the world are working to advance our understanding of these pathogens and develop new medicines. This podcast talks with several scientists on the frontier of superbug research, offering insight into what we know—and what the future of medicine may look like.

Explore inside a mosquito factory where millions of mosquitoes are bred weekly

In Medellin, Colombia, scientists are infecting Aedes aegypti mosquitoes with Wolbachia, a bacterium that wouldn't otherwise infect the species, but does block its ability to transmit dengue, Zika, yellow fever, and chikungunya. In the wild, infected mosquitoes would breed with wild mosquitoes, pass down Wolbachia, and thus reduce disease transmission.

How scientists are using molecules found in acidophiles to develop new medical treatments

The Berkeley Pit, an open-pit copper mine in Butte, Montana, that ceased operations in 1982 and is now filled with highly acidic water, is home to various species of fungi and yeast. These extremophiles produce unique compounds that may have anti-inflammatory benefits and have already been used to create an antibiotic for staph infections.

Why scientists are making robot insects

Insects have much to teach us about flying, jumping, moving quickly, and more. So, roboticists are studying how insects do the ridiculous things they do, like walk on water or jump fifty times their body height, to inform their design and engineering of a new slate of robots: tiny ones. Learn the future of this type of robot with this fascinating video with insights into both insects and robots.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

Mosquito necroprinting uses an insect's mouthpart as the printer nozzle

Mosquitoes are abundant, and their nozzles are 32-100 times cheaper to harvest than to create from scratch out of metal or glass. By coating the organic nozzle to increase its strength, researchers are employing necroprinting to create tiny structures at better resolutions than commercial alternatives.

How the Supreme Court established biotechnology patent law with an oil-eating microbe

While working at General Electric, microbiologist Ananda Chakrabarty engineered a strain of Pseudomonas that could break down multiple types of hydrocarbons and filed a patent on the bioremediation organism. Despite challenges over whether living things could be patented, the 5-4 decision held that genetically modified organisms could be patented because they were human-made inventions.

Swarms of mechanical bees may one day support natural pollination

Engineers are racing to create tiny robot bees that can be programmed to mimic natural bee behavior, helping in specific scenarios such as indoor farming and space agriculture. Battery life challenges may be solved by having these robots accompanied by a nearby "mother" drone power supply.

Superbugs could claim 1.9 million lives per year by 2050

The increased use of antibiotics combined with an aging population, is projected to result in an almost 50% increase in global deaths from antimicrobial resistance each year. At the same time, antibiotic use for livestock is expected to increase by 30% over the same time frame.

Learn about unconventional ways to clean up crude oil, including using moss and chickens

Studies show that microorganisms in chicken manure can break down the hydrocarbons in crude oil without producing toxic by-products. Scientists have also explored avoiding the environmental risks of chemical dispersants and synthetic adsorbents by using human hair and peat moss to adsorb crude oil, which can be taken up by their cuticles and porous structures, respectively.

Gut bacteria are evolving and can acquire as many as 100 new genes per year, on average.

Genetic engineering mice is one idea to reduce Lyme disease transmission

Wild white-footed mice are the main carriers of Lyme. A research team is hoping to genetically engineer mice, using CRISPR, to make the animals immune to Lyme. They're proposing a field trial where they would insert a gene with an antibody to Lyme infection to break the disease transmission cycle on a private island and then try it in Nantucket if that goes well. Simply killing the mice isn't an option because it would upend food webs. Unlike traditional vaccines, this "heritable immunization" would pass from one generation of mice to the next.

View the industrial applications of extremozymes, from food safety to antibiotic production

Extremophiles possess unique enzymes and organic molecules that have enabled them to adapt to and thrive in otherwise lethal environments. Because these conditions resemble those found in various areas of manufacturing and production plants, these organisms and their macromolecules can optimize industrial processes where conventional catalysts would lose their ability to speed up reactions.

Mosquitoes are the world's deadliest animal, but gene drives could kill them.

Explaining deep-sea mining, including its economic benefits and potential biomedical risks

Extraction via machines sweeping the ocean floor would reduce child labor and human rights violations currently occurring in land-based operations that collect the minerals needed for modern-day electronics. However, these sweeps may kill undiscovered organisms that possess biologies from which antibiotics could be derived and destabilize deep-sea ecosystems.

Some algae have helped remove microplastics from water after being bioengineered to clump together with these contaminants, forming an easily collectible microplastic-algae sludge.

Why extremophiles may play an important role in terraforming Mars

Possessing unique biochemicals that can detoxify extreme environments and resilience against the Martian surface that is lethal to humans, scientists are exploring whether colonies of these organisms can transform small areas of the Red Planet into future habitats for humans. Extremophiles may also be best equipped to serve as microscopic factories for the fabrication of essential polymers.

Despite privacy risks, scientists are using DNA in the air to assess ecosystem health

While DNA in soil and water samples has long been used for such analyses, airborne DNA is being incorporated into such efforts to monitor individual species abundance, detect invasive species, measure biodiversity, and determine the success of conservation actions. Future work may include detecting attacks from biological weapons.

Why bean leaves are an effective bedbug pesticide

No one wants a bedbug infestation because getting rid of them is infamously difficult. High heat and diatomaceous earth are two of the most effective bedbug pesticides, but there's another, obscure method: bean leaves! Watch this four-minute video...

Some mosquitoes are key pollinators—and eat disease-carrying mosquitoes.

Metamorphosis evolved over millions of years as species that hatched as smaller versions of adults started exhibiting genetic mutations that differentiated juvenile and adult bodies.

See examples of hyperaccumulators, the plants that can harvest heavy metals

These ideal species for phytoremediation possess biochemistry that allows them to absorb and store these elements without being poisoned by their accumulation. Pycnandra acuminata, one such plant, has blue-green sap due to an abundance of nickel, which it captures from the nickel-rich soil in which it grows.

Wolbachia is also being used to slash mosquito numbers

The naturally occurring bacterium does not naturally infect Aedes aegypti mosquitoes, but communities in locations including California and Texas have released male mosquitoes infected with Wolbachia and reported a significant drop in subsequent mosquitoes: When infected males mate with uninfected wild females, the eggs don't hatch.

Synthetic biology can prevent extinction by creating create disease-resilient plants and animals

Through gene editing and the deployment of artificial cells, scientists can leverage learnings from the genetic sequencing of animals with known resistances to protect endangered species. Gene editing of certain species, such as mosquitoes, can also reduce their ability to spread diseases like malaria between humans.

Over 1,500 insect species pollinate plants in the UK

These insects—including bumblebees, moths, butterflies, and beetles—play a crucial role in the reproduction of flowering plants, also known as angiosperms. They do so by transferring pollen from the male reproductive organ—the anther—to the female one—the stigma—which enables the plant to produce fruit.

How bedbugs have evolved immunity against pesticides

Bedbugs, once nearly eradicated in the United States due to the use of pesticides like DDT, have made a resurgence, with New York being declared the most bedbug-infested city. The primary reason for the return is the evolution of resistance in...

More than 39 million people are expected to die from antimicrobial resistance by 2050

In 2024, researchers published an incredibly detailed study aimed at predicting the real-world impact of antimicrobial resistance over the next 25 years. The key findings were clear: the superbug crisis is poised to get much worse and needs to be addressed. This article offers a clear, concise overview of the study, which was published in The Lancet.

Fecal transplants can help treat infections by transplanting healthy gut bacteria from a donor into a patient's gastrointestinal tract using samples of human waste, which are turned into a liquid mixture and often delivered via a colonoscopy procedure.

Scientists have found that sewage sludge used as fertilizer introduces various microplastics into soil, which persist in farmland for decades.

Gut microbiome rewrites may help reduce allergies

Researchers are investigating different strategies to determine if one day they could give people a combination of gut microbes to set them up for fewer allergies. In animal research, scientists have already prevented severe allergic responses in allergy-prone mice—supplying them with gut microbes from healthy, non-allergic human babies.