The business models behind vaccines

The basics behind mRNA vaccines

In this video, Yale experts Saad Omer, MBBS, MPH, PhD; Onyema Ogbuagu, MBBCh; and Akiko Iwasaki, PhD, explain the science behind COVID-19 mRNA vaccines.

How do vaccines work? Watch this brief 101

Watch this under-3-minute video explaining how vaccines use the body's immune system to prepare our bodies against viral and bacterial threats to our health.

Breaking down the different types of vaccine technologies

There are several different types of vaccines. Each type is designed to teach your immune system how to fight off germs—and the serious diseases they cause. This short overview breaks down the differences between the types.

Understanding TikTok-owner ByteDance's business model

ByteDance has ridden TikTok's major success to become the world's most valuable startup. This deep dive showcases some of the company's smartest moves and tactics, and where it's headed next.

COVID-19 vaccine breakthroughs are driving efforts toward a universal flu shot

mRNA and other technologies used for COVID-19 vaccines are being applied to influenza research. Scientists hope these advances will lead to a universal flu vaccine that protects against multiple strains and reduces the need for yearly shots.

How the 1918 pandemic spurred developments in virology and vaccines

This article provides an in-depth historical account of the 1918 Spanish Flu pandemic, including its impact on the global population and how its occurrence spurred significant advancements in the study of viruses—laying the groundwork for the...

See the evolution of Ebola vaccine and treatment development.

The 2026 Ebola outbreak in the DRC is spurring new Ebola vaccine development for the Bundibugyo species.

Most flu vaccines are still produced using chicken eggs

For decades, influenza vaccines have been made by growing viruses inside fertilized chicken eggs. Though newer methods using cell cultures or recombinant technology exist, egg-based production remains the primary global manufacturing process.

Supplement sales soared during the pandemic, alongside growing distrust of the health establishment, amplifying a trend that endures—even when some of the products don't even work.

The flu vaccine has evolved alongside discoveries of new virus strains

After influenza B was identified in 1940, researchers created a two-strain vaccine by 1942. The WHO later built a global surveillance system to track mutations, enabling vaccines to be updated annually to target the strains most likely to circulate.

How chaos helps explain why small market corrections can produce major economic instability

Oxford University complex systems professor Doyne Farmer discusses how predictions from many economic models are overly weighted toward simple relationships, such as supply and demand, and external shocks, such as the COVID-19 pandemic. However, real-world macroeconomic systems involve public and private actors interacting, producing feedback loops and cascading effects that resemble the oscillatory behavior seen in chaotic systems.

The COVID-19 pandemic led to a decrease in immunizations in the US and worldwide

Public health funds and resources that were diverted to COVID-19 response reduced efforts to combat polio and vaccinations for polio and other diseases declined during the pandemic, putting more people at risk for polio.

mRNA vaccines teach the immune system how to respond to a threat, using a molecule called messenger RNA.

The rise of telemedicine: A post-pandemic analysis

Before COVID-19, telemedicine remained on healthcare's periphery; however, the pandemic thrust it into the limelight, transforming how we approach medical care. This comprehensive review published by Press Ganey dives deep into the evolution,...

A history of vaccine rollouts

History tells us the public will tolerate risk of harm from a vaccine if their fear of the disease exceeds their fear of the vaccine.

Before vaccines, there was 'variolation': what was it?

Before the technology behind vaccinations was discovered, some keen observers of medicine around the globe noticed how previous infections could impact future ones. Learn about the techniques early physicians used before they had vaccines.

Governments are arguably very dependent on consulting firms like McKinsey and Deloitte

This podcast episode discusses the consultancy industry’s rise and how these firms make billions of dollars, even amid significant scandals.

How the World Bank's pandemic bonds were triggered during COVID-19

In 2017, the World Bank raised a chunk of emergency funds through bonds to help developing countries cover funds in the event of a pandemic. Had no pandemic occurred, investors would have received returns of 6% to 11%. But the global pandemic meant they lost all their money.

Meet six commercially available synbio products

An article exploring the science behind synbio products currently on the market, and projecting the products that can be expected over the next 10 years.

A timeline of major pandemics from 1899–2025

Modern pandemics have been defined by the race between globalization (which increases risk) and the development of new medicines. The Great Influenza epidemic claimed some 50 million lives, and the COVID-19 pandemic killed more than 7 million. In between, diseases like Ebola, cholera, AIDS, and more have devastated communities.

Show business is increasingly leaving Hollywood

Using tax incentives, states like Georgia, New Jersey, and New Mexico are luring studios to produce their films and television shows outside of California. Changing business models after COVID-19 largely influenced this change.

How universities manage their endowments

The CNBC video report explores how elite universities like Harvard handle their massive endowments, the ethical debates around their investments, and the tension between growing wealth and rising college costs. If you’re curious about where billions of dollars in higher education go, why tuition remains high despite huge endowments, or how student activism is pushing for ethical investing, this video offers a revealing, accessible look at the financial engines behind America’s top colleges.

Read about Palantir's role in the COVID-19 vaccine rollout

Palantir developed Tiberius, a software service that supported the public-private partnership spearheaded by then-President Trump to roll out COVID-19 vaccines. The software tracked state-by-state vaccine allocations, as well as COVID-related hospitalizations.

The plasma-selling industry is expected to reach $50B by the end of the decade

About 55% of your blood volume is plasma, the liquid part of blood created from water, proteins, minerals, and salts absorbed through the digestive tract. This 49-minute podcast episode explores the business of plasma—part of a global industry expected to be worth $50B by 2029.

What are universal vaccines?

As viruses mutate and develop, vaccines have to adapt, leading to regular recommended injections like flu shots. Researchers are working to develop universal vaccines that aim to protect against multiple virus variants if not entire virus families. These vaccines work by creating broadly neutralizing antibodies (bnAbs) that target aspects of viruses that don't typically mutate and are integral to the virus' survival.

A heatmap showing the drop in infectious diseases post-vaccine deployment

The number of infected people, measured over 70-some years and across all 50 states and the District of Columbia, declined significantly after vaccines were introduced.

Ozempic parent company Novo Nordisk operates under a 'foundation ownership model'—meaning that a foundation holds the majority of the company's voting power, while most of its equity is owned by public investors.

Scientists from the frontline discuss the future of antibiotics and superbugs

Superbugs are a very real problem, but researchers around the world are working to advance our understanding of these pathogens and develop new medicines. This podcast talks with several scientists on the frontier of superbug research, offering insight into what we know—and what the future of medicine may look like.

Variola: the second-deadliest virus on Earth

Because it was declared eradicated in 1980, many forget smallpox is one of history's deadliest diseases—in its final century, it's estimated to have claimed 500 million lives. This 11-minute video from production studio Kurzgesagt takes a look at...

Menopause may become a $600B industry

Companies marketing products and supplements to alleviate menopause symptoms and make life easier during this life stage have become a gold mine. This 2022 article explores how and why companies have swooped into this space, and whether you should trust them or not.

Visualize the global supply chain of medicine, which may begin with basic research in the US, but outsource intermediate steps.

Find out how airlines quietly became banks

Some experts suggest airlines lose money on every flight. This video dives into how airlines have leveraged their loyalty programs to make billions of dollars, effectively evolving into banks.

Biotech is trying to boost drug production efficiency—using chicken eggs

A company called Neion Bio is genetically engineering birds in a bid to produce medical compounds, a herculean task that scientists have struggled with for decades. The US FDA has approved only one chicken-derived drug in the past—an expensive treatment for a rare liver disorder. (Some users may encounter a paywall.)

A scientist successfully treated her own breast cancer by injecting the tumor with lab-grown viruses.

Small genetic changes that accumulate over time force flu vaccines to be updated regularly.

Explore a 3D model of the influenza virus

This interactive 3D model reveals the influenza virus’s structure—its outer coat and spike proteins—and compares it with other well-known viruses, offering a clear view of how flu differs from pathogens like HIV or coronaviruses.

COVID-19's shock to employment rates sparked some economists to fear deflation

COVID-19 simultaneously disrupted the supply chain and the labor market. Since the unemployment rate had hit record highs, some economists were worried that the supply chain would recover before the labor market. If that had happened, businesses would have been producing goods, but no one would have been able to buy them because they wouldn't have the disposable income to do so.

What is vaccination? The World Health Org explains

Read up on the basics of vaccinations with this 101 from the World Health Organization, the public health arm of the United Nations.

The COVID-19 pandemic both boosted Peloton's business and shook it up completely

While demand for Peloton's at-home fitness equipment soared during the pandemic, the company didn't necessarily have the infrastructure to support the breakthrough sales. In 2021, Peloton bought Precor—a fitness equipment manufacturing company—to help boost domestic production and decrease a backlog of orders.

Understanding vaccine side effects

A vaccine is a medical intervention, and as with any medical intervention, may have side effects. This article discusses side effects and adverse events related to vaccination.

The creator economy—which is projected to be worth as much as $480B by 2027—is a system powered by people creating online content for monetizable audiences.

In 2023, venture capital firms invested $170B in over 15,000 US companies

That's a significant drop from 2022’s $242B, reflecting market uncertainty but continuing VC’s role in scaling transformative ideas. Rooted in early risk-sharing models, venture capital took off with firms like ARDC in 1946, later evolving into today’s influential players like Sequoia Capital and Andreessen Horowitz.

See how the Pfizer-BioNTech vaccine's mRNA instructions teach your own cells to trigger an immune response against the coronavirus's spike protein.

'Planet Money' debates the financial indicators that defined 2025

In this end-of-year episode, "Planet Money" stages a playful debate over which economic indicators best captured the chaos of 2025—from tariffs to AI bubbles—and which signals may matter most as the US economy heads into 2026.

Breaking down how and why 5G will change the world

The jump from 3G to 4G networks was pretty huge, and 4G to 5G is many times greater and is almost difficult to comprehend. This nine-minute video dives into how 5G will transform our world.

The firms running America's voting systems

Three companies make up over 90% of the US market share around voting systems, and like any company, they're priorities aren't always aligned with the public's. Dive into the industry of voting machines in this investigation piece from the Guardian.

How to prevent a worst-case scenario with synbio

Author and entrepreneur Rob Reid reviews the risks of a world where more and more people have access to the technology needed to create a doomsday bug that could wipe out humanity.

F1 is a billion-dollar industry

But that money doesn't come easily. Team principals have to constantly ensure money is coming in to fund their million-dollar cars every weekend. This CNBC video explores all the costs of running a team. It also shows how team principals woo sponsors and find ways to maximize their technology with a cost cap.

How a single company hooked the world on herbicides

How harmful are today’s herbicides for us humans, and for the environments they’re seeping into? And do we really need weedkillers to feed the world?