Western babies often lack a gut microbe common elsewhere.

Gut bacteria are evolving and can acquire as many as 100 new genes per year, on average.

In 2026, University of Cambridge researchers reported that a group of gut bacteria called CAG-170 may be a key marker of good health, occurring far more often in healthy individuals and less commonly in people with chronic diseases.

Some animals, including certain tropical ants, have little or no microbial populations in their gut, upending the idea that all animals rely on this ecosystem to help maintain their health and proper functioning.

Gut microbiome rewrites may help reduce allergies

Researchers are investigating different strategies to determine if one day they could give people a combination of gut microbes to set them up for fewer allergies. In animal research, scientists have already prevented severe allergic responses in allergy-prone mice—supplying them with gut microbes from healthy, non-allergic human babies.

What happens when the gut microbiome is out of whack?

An imbalance in gut microbiome flora can lead to a condition known as dysbiosis. This condition is typically characterized by a drop in microbiota diversity and an increase in harmful unicellular and acellular organisms, such as viruses, that can negatively impact the host's immune system and overall health. Genetics, infections, dietary choices, antibiotics, food additives, artificial sweeteners, and other lifestyle and environmental factors can cause dysbiosis.

There are up to 100 trillion microbes in the gut, and maintaining the relative balance in this ecosystem is important for our health.

Improved 19th-century sanitation meant kids encountered polio later, with worse results

Almost all children likely used to contract poliovirus, but scientists suggest that when infants encountered it very early in life—due to poorer conditions and hygiene—they still had some maternal protection from pregnancy or through breastmilk, so the symptoms were more flu-like.

Probiotics, which are living bacteria and yeasts, are not recommended for most patients.

Trillions of bacteria, viruses, fungi, protists, and archaea live in our guts, producing a wide range of molecules, hormones, and more—underscoring the immune system's pivotal role in the microbiota-gut-brain axis.

Embracing poor hygiene in early life won't stave off allergies

The hygiene hypothesis, first proposed in 1989 by British immunologist David Strachan, suggests that early life exposure to microbes—like those from farm dust or pets—properly trains our immune systems to respond to threats. But sometimes the idea is misinterpreted: It doesn’t mean that poor hygiene—like failing to wash hands–will help ward off allergies; that type of behavior leads to infections and won’t help with allergy prevention.

Researchers generally group gut bacteria into six different categories, with varying amounts of these microbes residing in different parts of the digestive tract.

Most of the world’s population has difficulty processing lactose—but that’s not an allergy

Lactose intolerance is a digestive condition that occurs when the small intestine has difficulty breaking down lactose, a sugar found in products like milk or cheese, leading to symptoms such as diarrhea or bloating. Almost 70% of the world’s population may have lactose processing issues, particularly in Asia and Africa. This is different from a condition called cow's milk protein allergy—an immune system disorder that can cause hives and anaphylaxis.

A technical review of what researchers know about the gut microbiome

This overview from the National Institutes of Health provides a deeper (but still accessible) look at the different bacteria in the gut, how the microbiome develops through life, its purpose, and more.

About two-thirds of humans lose their ability to produce lactase after weaning

Lactase is an enzyme that digests lactose—a sugar in milk and dairy products. While genetics strongly determines lactase persistence, factors like famine, disease exposure, and gut bacteria also influence symptoms and evolution.

Exposing fetuses to certain flavors in the womb could lead to children being less picky eaters

A new study found that 3-year-olds were less averse to the smell of vegetables they had been repeatedly exposed to in utero, suggesting that what mothers eat in late pregnancy can leave a lasting imprint on their children's tastes.

Modern conveniences may be contributing to allergy increases

A combination of genetics and how the environment changes our genes are likely contributing to the rise in allergies. But daily conveniences, such as dishwashers and packaged baby food, also change the level of bacterial exposures in early life, with potential implications for allergy development, experts from Mount Sinai Health System state in this video discussion.

Newborns have a strong sense of smell

Babies are drawn to their mother's smell—and the particular odor of their mother's breast milk—within days, even as their vision remains blurry for months after birth. In the womb, the olfactory center also forms in the early stages of development.

Research suggests the cleanliness of the ISS may make astronauts unhealthy

The International Space Station's sterile conditions deprive astronauts of the opportunity to strengthen their immune systems through microbial exposure. To address this problem, future missions may use probiotic-based cleaners and foster diverse microbes in space habitats.

The gut microbiome—a complex community of up to 100 trillion microbes—has a changing composition, influenced by our life stage, diet, medications, environment, and other factors.

How the microbiome affects your health

The gut microbiome is so influential to overall human health that some researchers consider it a separate organ. Its conditions, influenced by environmental and lifestyle factors such as medication and exercise, contribute to immunity, metabolism, inflammation, medical treatment efficacy, brain development and function, and the development of disorders and diseases, including asthma, depression, inflammatory bowel disease, and Alzheimer's.

Humans can get tuberculosis from drinking raw milk, but milk pasteurization kills pathogens, including the bacteria that cause tuberculosis.

Bidets have been considered taboo throughout US history

While bidets are a typical household essential in Europe, Asia, and South America, they remain uncommon in the US. Associations with infertility, the aristocracy, and brothels helped fuel their unpopularity in the states.

Neglected tropical diseases affect more people than the population of Europe

This group of conditions, which includes hookworm, sickens roughly one in seven people on the planet—a tally which dwarfs Europe's population of roughly 450 million. International cooperation and donations are helping to control some of these illnesses, which can be caused by parasites, viruses, and bacteria. They're all treatable or preventable, but primarily occur among poor, isolated communities that may not receive adequate care.

What constitutes a 'healthy' diet?

A natural diet, typically high in plant-based foods and low in processed foods, appears to be the main contributor to a healthy, diverse gut microbiome.

Can the gut microbiome drive addiction?

New research suggests an imbalance of gut microorganisms may influence the likelihood of addiction and addictive behaviors by increasing the severity of withdrawal symptoms, triggering brain inflammation in regions of impulse control, and more.

The gut microbiome's community of viruses is collectively known as the virome, but most of its viruses remain unidentified.

Amish kids have far fewer allergies than the general population

Only about 7% of Amish children in a northern Indiana community have tested positive for common allergens in routine skin prick tests, whereas half of the general US population tests positive for them. Asthma is also extremely uncommon among the Amish, even when compared with other farming communities. Researchers are interested in exploring if approaches like exposing kids across the general population to Amish farm dust might stave off some allergies.

What's next for gut microbiome science?

A Stanford microbiologist explores what we don't yet know about the gut microbiome—such as whether we can engineer the bacterial species within it—and the current scientific advances in the field.

Bacteria in our intestine influence the brain via the gut-brain axis.

Adults are developing food allergies that they didn’t have as children

Research published in 2019 found that almost half of 40,000 surveyed adults with food allergies developed a new food allergy as adults, underscoring that our immune systems may newly misclassify substances later in life.

How a worm helped give the southern US its reputation

"The germ of laziness" that blanketed the southern US for centuries with unshakable fatigue, brain fog, and distended bellies paired with emaciated frames was actually a worm. This parasitic worm lives in the gut, where it can stay up to five years, laying up to 10,000 eggs daily. Hundreds of millions of people worldwide continue to suffer from hookworm infections, often obtained by walking barefoot across infected soil.

Even in recent history, adaptations to the environment drove human evolution

Through genetics, environmental pressures, and cultural influences, humans have evolved to tolerate lactose, develop varying skin pigmentation, and acquire genetic resistance to diseases like bubonic plague. The metabolic and digestive systems of Indigenous peoples have adapted to their diet, which is influenced by the availability of food and water.

Gut microbiome experiments involving transfers of gut microbes from depressed people to rodents indicate that the rodents may then display depression-like symptoms.

The gut microbiome may play a major role in autoimmune disease and symptom flare-ups

Certain unhealthy foods can promote gut bacterial growth and inflammation in the lining of the gut, potentially disrupting its lining—leading to a leaky gut that may allow pathogens to dribble out into the bloodstream, fueling further inflammation that can both cause disease flare-ups and set the stage for future disease development.

Infants are particularly at-risk for ear infections

The Eustachian tubes, which connect the middle ear to the upper throat and help to drain fluids and equalize pressure, are relatively flat at birth, making it hard for gravity to assist with drainage. The angle of these tubes changes and becomes steeper as we age, making fluid buildup in the ear canal less common.

Exercise causes diet-independent changes in the gut microbiome.

Children under 5 account for 76% of all malaria deaths in Africa

The main hypothesis for why the disease hits this age group the hardest is that children this young have still-developing immune systems. Pregnant women and people with HIV/AIDS are also at higher risk of severe infection.

Lactose intolerance is not the same as a dairy allergy

Lactose intolerance can develop in adulthood and can be influenced by genetic factors, culture, and dietary practices. Times of famine may have favored those who could digest dairy, naturally selecting them more, resulting in lactase persistence.

Babies taste food in the womb via amniotic fluid, and it may influence future taste buds.

Microbes are essential to creating the many varieties of cheese, influencing texture and taste

Microbes break down proteins and fats and produce compounds with distinct tastes. These microbes can include bacteria (like the one used to give Swiss its trademark holes), molds (like the ones that give blue cheese its distinctive veining), and countless other tiny organisms.

Researchers are investigating how altering the gut microbiome may influence the development of rheumatoid arthritis, which is an autoimmune disease.

Some dementia cases may be linked to treatable microorganism infections in the brain.

Why South Korean women are having fewer babies

For decades, Asian countries have been combating dwindling birth rates by basically bribing families into having more children: offering government-subsidized housing, free IVF treatments, and even straight-up cash handouts. It hasn’t worked. In this BBC video, a TV producer, a cartoonist, and a private-school teacher explain their views on having children in 21st-century Korea.

Vitamin B1 is linked to gut motility—helping fight constipation—in 2026 research

A study published in early 2026 found a link between vitamin B1 and the successful movement of food through your GI tract, known as gut motility. The work incorporated genetic and survey data about poop frequency to identify genes associated with gut motility and then separately linked poop frequency data with how much vitamin B1 people ingested, theorizing that the vitamin supports the production of acetylcholine, a neurotransmitter that stimulates GI system contractions.

Unconditional birthright citizenship is rare outside the Americas.

Most people with East Asian ancestry are genetically predisposed to be less smelly.

Fecal transplants can help treat infections by transplanting healthy gut bacteria from a donor into a patient's gastrointestinal tract using samples of human waste, which are turned into a liquid mixture and often delivered via a colonoscopy procedure.

Superbugs evolve defenses against medication, then share them with neighbors

One reason antibiotic resistance spreads so quickly is that bacteria have multiple mechanisms allowing them to share genetic material. This short video offers a concise explanation for each of these mechanisms, and animation that helps viewers understand how antimicrobial resistance can quickly spread from one organism to another.

Microbial research suggests shifts in diverse populations may help an invasive species establish itself

In 1958, English ecologist Charles Elton suggested that diverse ecosystems should be more resistant to invasive species because gaining a foothold would be more challenging when resources are more thinly spread. However, in lab-grown microbial ecosystems with greater biodiversity, population volatility opened more ecological roles that invasive species could easily fill.

Antibiotic resistance is a growing global health problem

Over decades, bacteria have grown increasingly resistant to antibiotics. This resistance now causes an estimated 1.27 million deaths each year and is associated with nearly 5 million deaths worldwide, according to the World Health Organization.