Genetic analysis indicates that every organism on Earth evolved from a single cell

Evidence suggests the first cells on Earth were bacteria

About 4 billion years ago, these single-celled organisms harvested carbon dioxide and sunlight to produce their own food and oxygen, setting the stage for the evolution of oxygen-breathing life forms. Archaeabacteria, which thrive on inorganic molecules in extreme habitats on Earth today, were also among the earliest organisms.

How humans evolved from single-cell organisms

Humans have had a long history. 3.8 billion years in the making, to be precise. From the primordial puddle to the modern day, here's how humans have evolved from the first life.

Humans have existed for just 0.004% of Earth’s history

Born from the remains of the molecular cloud that birthed the sun, Earth experienced planetary-scale collisions, asteroid impacts, and lava seas. Life became possible after the planet cooled and formed a thin crust, atmosphere, and oceans.

Green algae have lived on Earth for about 1 billion years, roughly twice as long as the first plants.

Where do genes come from?

There are many more genes on Earth today than when microbial life first spawned on the planet about four billion years ago. Many of these newer genes grew from genetic mutations, misprints that slowly drift from the original blueprint via cellular division. If these mutations drift far enough, they can establish a new family of genes, though this process can take well over a million years.

Abiogenesis explains how Earth's natural processes could have formed organic matter

The theory details how chemical interactions in hydrothermal vents and shallow ponds billions of years ago could have created lipids, proteins, and RNA. As these interactions involve water, life is thought to have started in oceans.

Panspermia, the theory that cellular life came from a different planet

One of the most profound mysteries of human life on earth is the presence of living cells: organic, self-organizing, reproducing creatures with a drive to survive within given set conditions. Traditional theories posit life came from divine...

Early Earth lifeforms likely made energy via mineral reactions, not sunlight

Earth's initial atmosphere was filled with carbon dioxide, methane, and water, with most oxygen locked away in the rocky crust. Over time, bacteria evolved to slowly release that oxygen into the atmosphere by breaking down rock.

Before discovering cells, life was believed to emerge suddenly from inorganic matter

Popularized by Aristotle in the 4th century BCE, spontaneous generation was used to explain phenomena like mice appearing in seemingly sealed grain storage. The invention of the compound microscope in the late 16th century led to the identification of cells as the basic unit of life, but it was not until 1855 that their origin from preexisting cells was established.

The first appearance of bioluminescence was at least 540 million years ago

After analyzing fossils, genetic data, and statistical methods, scientists believe octocorals were the first organisms to evolve light-producing abilities. As a result of independent evolution across at least 94 species, this phenomenon is connected to a diverse range of behaviors.

The history of Earth's breathable atmosphere, made possible by photosynthetic bacteria

Between 3.2 billion and 2.8 billion years ago, threadlike microorganisms called cyanobacteria began consuming available water vapor, carbon dioxide, and sunlight to produce oxygen. However, molecules released from Earth's interior by volcanoes consumed this oxygen via chemical reactions, preventing it from accumulating until volcanism had sufficiently decreased about 2.4 billion years ago.

Learn how chloroplasts—the photosynthesis factories—may have once been independent cells

Possessing DNA of their own that differs from that of their host cell and surrounded by cellular membranes like those observed in bacteria, chloroplasts are believed to have evolved from a cyanobacterial cell. The endosymbiotic theory explains that these organelles were absorbed into larger cells, leading to the photosynthetic cells seen today.

Lining up every microbe on Earth would stretch to about 105,000 light-years

There are about 10²⁷ such organisms on the planet, many of which are adapted to produce energy through uncommon reactions in unconventional environments, such as within rocks or near volcanoes on the ocean floor. Studies of these organisms have reframed astrobiologists' search for life beyond Earth by broadening the parameters under which life can exist.

Some organelles are believed to have once been independent cells

Mitochondria and chloroplasts, which are both responsible for energy production in cells, have DNA distinct from that of their host cells and are surrounded by cellular membranes resembling those of bacteria. Through symbiogenesis, these and other specialized structures were absorbed into larger cells, forming the modern-day biological units.

Extremophiles were likely to have been Earth's first, and are expected to be its last, organisms

Their ability to survive in an enormous range of environmental conditions, including some resembling what has been modeled to have existed relatively shortly after Earth's formation, makes them the leading candidates for enduring the increasing solar intensity and the subsequent effects (e.g., zero-oxygen atmosphere, evaporated oceans) expected in the coming billions of years.

Cell theory originated from microscopic observations of cork and dental plaque

In the mid-1600s, Robert Hooke identified compartment-like structures—which he called cells—in cork, and Anton van Leeuwenhoek discovered bacteria in samples of his dental scrapings. Almost 200 years later, Matthias Schleiden and Theodor Schwann showed that plants and animals, respectively, are composed of cells, proving that cells are the foundation of all living things.

Why genetic similarities between humans suggest a past near-extinction event

Researchers have found that low genetic diversity among humans—even those on opposite sides of the planet—may result from a breeding population of as few as 1,280 adults, estimated to have existed 930,000 years ago. This genetic bottleneck may have resulted from a near-extinction or from a small population of human ancestors, from which we all descend, that broke off from a larger population.

The key ingredients to life on Earth—and elsewhere

Life can only arise in incredibly specific conditions, an abundance of certain substances like water and phosphorus, lots of time, and the right proximity to a heat-and-light-providing star. These two experts on evolution of life say above all, life requires luck. Here's a list of eight ingredients to life.

An analysis of fossilized reefs from northern Africa and Germany suggests that shallow water corals and photosynthetic algae formed the mutualistic partnership seen today between 419 and 359 million years ago.

The messy story of humanity's genealogical past

For decades, scientists viewed the human fossil record and concluded Neanderthals, an early hominin, came before homo sapiens, or modern humans. The story became more complicated as technology advanced and ancient DNA samples were analyzed. This video breaks down the evidence, concluding the development of humanity was a lot messier than previously believed.

The formation and breakup of Pangaea altered Earth’s geology and biodiversity

Coming from the Greek words for “all” (pan) and “Earth” (gaia), the supercontinent existed from about 320 million to 195 million years ago. The tectonic activity that split Pangaea into today’s continents may one day bring the continents back together, forming Pangaea Proxima.

Hypotheses on the origins of Earth's water, from comets and asteroids to magma oceans

Before Earth's atmosphere formed, any liquid water would have boiled off, preventing the accumulation of water early on to create today's oceans. Planetary scientists continue to debate whether this water was delivered later from comet or asteroid collisions or via reactions between iron oxide in Earth's molten surface and hydrogen gas from the planetary nebula.

Spontaneous metabolism may give clues to origins of life

Read this article to learn more about the discovery that suggests that metabolism could have begun spontaneously on our planet—and why it means that scientists may need to rethink how we define life’s origins. A team of researchers at the...

Because it is observed in organisms that are not closely related, biofluorescence is thought to have emerged independently many times in nature—over 100 in fish alone.

Explore the independent lines of evidence behind the theory of evolution

Gradual changes in organisms have been directly observed through artificial selection—humans purposely selecting organisms to breed to pass on specific traits—and in organisms with short lifespans, such as insects and microbes. Analyses of DNA and anatomical structures across different species, as well as fossil records, also reveal ancient shared ancestry consistent with natural selection.

From the Big Bang to present—a timeline

A timeline for everything, from the Big Bang to the beginnings of life on Earth. This article lays out, in spans of billions of years, what was happening in the universe as it became the universe. Starting from the Planck era, the earliest known meaningful time, to the probable "Big Crunch" 30 billion years from now, see how the universe has existed and persisted.

RNA may have allowed life to exist before DNA

The emergence of living organisms from non-living matter—abiogenesis—requires both a molecule that encodes genetic information and proteins that perform biochemical processes. However, because DNA and protein depend on one another, some biologists theorize that RNA, which can both store information and perform functions, preceded both and originated life.

Bioluminescence became common in the ocean to support survival in dark environments

Despite seeming like a rare ability in land animals and unseen in plants, bioluminescence has evolved at least 29 times across marine species, indicating its necessity for survival where hiding spots are rare and highlighting how environments provide evolutionary pressure.

The history of the gene: an interactive timeline

Humans didn’t need modern technology to figure out that kids tend to look like their parents. But what did humans believe about genetics before we knew about DNA or cells in general? Explore this interactive timeline to see how philosophers and scientists throughout the ages tried to explain how traits are passed from generation to generation.

Metamorphosis evolved over millions of years as species that hatched as smaller versions of adults started exhibiting genetic mutations that differentiated juvenile and adult bodies.

Dinosaurs emerged 245 million years ago when Earth’s continents were still conjoined

Once the supercontinent split apart, dinosaurs evolved into thousands of species as they adapted to their changing environments. All non-avian dinosaurs went extinct about 66 million years ago following an asteroid impact, while avian dinosaurs evolved into today’s birds.

The oldest DNA recovered so far is 2 million years old

The oldest DNA recovered so far is about 2 million years old and has given scientists an unadulterated peek into ancient history. This nine-minute video explores the findings and implications of the DNA, which was pulled from frozen soil in...

Even in recent history, adaptations to the environment drove human evolution

Through genetics, environmental pressures, and cultural influences, humans have evolved to tolerate lactose, develop varying skin pigmentation, and acquire genetic resistance to diseases like bubonic plague. The metabolic and digestive systems of Indigenous peoples have adapted to their diet, which is influenced by the availability of food and water.

View a sample of the bioluminescent tree of life

This diagram shows 42 different light-producing organisms, from bacteria and fungi to worms, fish, and crustaceans. It illustrates how the ability to produce light has appeared multiple times across the tree of life, rather than stemming from a single ancestor.

Within massive clouds of gas and dust called nebulae, many stars often form on short cosmological timescales and collectively orbit one another, creating groups called clusters.

The 300-million-year period where Earth looked like a snowball

Life has existed on Earth for at least 3 billion years, but the planet has not always looked like it does today. Rather than the blues and greens of our modern globe, for a 300 million-year period, the Earth was covered in ice and snow, from the poles to the equator. Surprisingly, life was thriving at the time.

Unique species evolved independently on each Galápagos island

The islands formed over millions of years because of a hot spot in the Nazca Plate, where magma breaks through and forms volcanoes. As these islands drifted, plants and animals became secluded, making each island its own an isolated experiment that would influence Charles Darwin's theory of evolution.

The cosmic dark ages: before stars existed

The theories behind the Big Bang suggest the process of the universe beginning to the creation of stable, neutral atoms took just half a million years. But the transition from such atoms to star formation took surprisingly much longer, upwards of 100 million years. Why? This deep dive explores the science behind the unique physical composition of the so-called cosmic dark ages.

See how each of the more than 2 million known species relates to each other—and to common ancestors—in this zoomable tree of life.

Humans have speculated about alien life since ancient times

Around 50 B.C.E., Roman poet and philosopher Lucretius shared the idea that alien life was possible, which was put forth by Greek philosopher Epicurus. The writing is believed to be the first straightforward assertion in Western literature that aliens must exist.

Here's how humans migrated across the world

From our deepest origins in Africa all the way to the Americas, by looking at the fossils and archaeological materials we have been able to trace the path our ancestors took during thee short window of time when we took over the world.

Why the Big Bang theory is the most well-supported explanation for the origin of the universe

Multiple independent lines of evidence—galactic redshift, element ratios, cosmic microwave background radiation, and large-scale cosmic structure—all point to a single origin about 13.8 billion years ago. Before Edwin Hubble, many astronomers believed the entire universe was contained within our galaxy.

Underwater volcanoes significantly contributes to marine extinctions during the Triassic period

An analysis of ocean basins in the Tibetan Plateau helped identify three major periods of volcanism—250-248, 233-231, and 210-208 million years ago—which released significant amounts of greenhouse gases, altering ocean chemistry. The low-oxygen conditions may help explain half of Earth's Triassic extinctions.

The earliest evidence of cancer was found in a 1.7-million-year-old fossil—discovered in the toe of an ancestor of modern-day humans.

Georges Lemaître, a Belgian Catholic priest who proposed the Big Bang theory in 1931, became president of the Pontifical Academy of Sciences in 1960.

A timeline of human fossil discoveries

A key part of writing a coherent story about our origins is finding and identifying the remains of our ancestors and understanding their significance. Scientists will not always agree on identifications and opinions will change as new find are made and new ways of studying them are developed.

The cycling of carbon via tectonic activity may have facilitated life on Earth

Plates sinking into Earth’s mantle pull carbon from the surface, helping stabilize the atmosphere and climate by removing greenhouse gases from volcanic eruptions. At the same time, magma is a significant contributor of heavy metals and other crucial minerals for life to the surface.

There are five key mechanisms—small population size, nonrandom mating, mutation, gene flow, and natural selection—that drive evolution, or the change in the abundance of specific genetic traits found within a population.

Blood has evolved many times over hundreds of millions of years, resulting in different blood colors and compositions—and there are even some organisms that don't need blood at all.

Earth's first oceans may have been as much as 230 degrees Celsius (446 degrees Fahrenheit), with atmospheric pressure preventing them from boiling.