The ancient Egyptians developed the first pregnancy test—and scientists tested it in the 1960s and discovered it was accurate about 70% of the time.

Read the 1963 study testing out an ancient Egyptian pregnancy urine test.

Modern pregnancy tests detect a specific hormone in a woman's urine or blood.

Many of the new prenatal genetic tests for rare genetic conditions are inaccurate

Established screening tests for Down syndrome in utero are reliable and accurate. But a New York Times investigation into expanded prenatal genetic tests for very rare diseases—much rarer than Down syndrome—found that more than 80 percent of the positive test results turned out to be wrong based on follow-up testing. These expanded tests for rare diseases are performed from a blood draw at 10 weeks of pregnancy and aim to detect chromosomal abnormalities linked to rare diseases. Companies that offer these controversial tests counter that it's only a screening test—not a diagnosis—picking up true positives and noting that patients can and should be counseled about what the findings mean. (Some users may encounter a paywall.)

Scientists first observed a sperm and an egg uniting in 1876

Throughout human history, scholars and researchers have speculated on the origin of human reproduction. It wasn't until the late-19th century that the physical process of egg fertilization via sperm cells was observed (in sea urchins), forming the basis for modern fertility research.

The pregnancy test industry is worth roughly $769M

The inventor of the at-home pregnancy test, Margaret Crane, largely hasn't taken credit for her invention until recently.

The first successful IVF pregnancy was in the United Kingdom in 1978

Gynecologist Patrick Steptoe and his collaborator Robert Edwards, a biologist, attempted to fertilize a human egg cell in a petri dish 101 times before finally succeeding. This resulted in the birth of Louise Brown—at the time referred to as a "test tube" baby—in 1978, who was born into the spotlight.

The first newborn screen for diseases was developed in 1961.

Premarin, the hormone medication derived from pregnant horses, is 'PREgnant MARes urINe'

Scientists in the late 1920s and early 1930s discovered estrogens could be extracted from human placenta, and then isolated it from the urine of pregnant women. But researchers discovered the urine of pregnant horses had similar substances and the horse product was much easier to collect in significant amounts—leading to Premarin.

Only about 0.0001% of sperm, on average, successfully reach the uterine cavity

We've evolved to make pregnancy a complex and difficult process. From the initial development of the blastocyst, to the energy and nutrients needed to grow a new human, our bodies are both fighting and supporting fetal development.

Ancient Egyptian papyrus from 16th century BCE seems to reference tinnitus

Ancient Egyptians wrote that they treated "bewitched ear" with herbal concoctions that involved frankincense and other ingredients, which were placed in the ear.

A DNA paternity test will show a less than 1% probability if the tested man is not the actual father.

A baby's due date is calculated from the first day of the last menstrual period—not when sexual intercourse occurred.

Why are archaeologists brewing ancient beers?

Archaeologists have managed to brew beer from yeast found inside jugs abandoned thousands of years ago. This article explores why scientists are recreating these ancient beverages and what they hope to learn. People have been drinking beer for...

Tour the ancient world via beer

What did the people of yesterday make of beer, and how exactly did they make it? Explore the timeless beverage in this guide to ancient beers from around the world. Archaeological evidence suggests the rise of beer brewing may have coincided with humanity's shift from hunters to farmers. According to this article, beer was first enjoyed in ancient Mesopotamia, where paintings, poems, and myths glorified the porridge-like brew.

The history of ectogenesis and artificial wombs

While the science of artificial wombs is new, the idea goes back to a 1923 Heretics Society of the University of Cambridge lecture where an English biologist was one of the first people to propose an egg could be fertilized outside the womb. This...

Child mortality rates since ancient Rome

One of the great achievements of modern humanity has been the sea change in child mortality rates—the chance that a newborn eventually lives past puberty. For thousands of years, children had a 50% chance of not entering adulthood. About 300 years...

Two dogs were able to detect prostate cancer in 98% of patients in one study

In this small study published in 2015, two highly trained German Shepherd dogs sniffed hundreds of urine samples and were able to accurately detect prostate cancer—sniffing out certain volatile organic compounds—in almost every single case. One dog was correct 98% of the time and the other correctly identified patients 100% of the time. (Some users may encounter a paywall.)

Genetic blood test offers an estimated clock on when Alzheimer's symptoms may appear

The 2026 research finding from researchers at Washington University School of Medicine in St. Louis—if validated in broader populations—suggests that an already available blood test could estimate when Alzheimer's symptoms may begin within a margin of several years. The test detects a protein called p-tau217 found in blood plasma and the researchers incorporated the findings from that blood test into a statistical model to come up with the symptom timeline predictions.

Researchers believe beer was being brewed 13,000 years ago

In 2018, archaeologists discovered traces of a wheat-and-barley-based alcoholic beverage near Haifa, in modern-day Israel, and believe it was produced by the Natufian people.

Modern genetic testing stems from a 1950s discovery about the cause of Down syndrome.

The earliest record of dream interpretation dates to Ancient Sumer, an analysis of a Sumerian priest king's dream around 2700 BCE.

Understand the complex, biological journey of pregnancy with this science explainer.

In 1822, French scholar Jean-François Champollion deciphered Egyptian hieroglyphs using the Rosetta Stone.

Pregnancy at older ages increases the chances of fetal abnormalities

Chromosomal irregularities are more likely at older maternal ages so genetic testing for a fetus of mothers-to-be at age 35 and older is often recommended. Conditions that can be screened for in utero include cystic fibrosis, Tay-Sachs disease, sickle cell disease, Down syndrome, spina bifida, Duchenne muscular dystrophy, and more.

Reconstructing an average day in ancient Egypt

Egyptologists can reconstruct the intimate details of everyday life in the ancient civilization by studying the archaeological material preserved in tombs, monuments, and partially intact neighborhood layouts. Watch a comprehensive tour of the daily habits and lifestyles of ancient Egyptians with expert Dr. Joann Fletcher.

Babies taste food in the womb via amniotic fluid, and it may influence future taste buds.

The Royal Game of Ur, which dates back as far as 2600 BCE, is believed to be one of the oldest board games in the world.

Silicon Valley startups Orchid, Nucleus, and Genomic Prediction are selling so-called polygenic tests for prospective parents

These tests claim to show how at-risk a hypothetical baby would be for genetic syndromes. The newfound industry has prompted ethical and medical debates, with critics questioning their accuracy and highlighting the potential problems behind pursuing the perfect baby.

The ultrarare 'Er' blood type has been documented only about 40 times, and it can cause devastating pregnancy complications.

The Ishango bone suggests mathematics was born about 20,000 years ago

Ancient civilizations developed mathematical systems for various purposes, including the Egyptians for the construction of the pyramids and the Ancient Greeks for logical reasoning in theorems. However, these systems were predated by the Ishango bone—found in the Democratic Republic of the Congo—whose notches suggest a base ten system, prime numbers, and simple mathematical operations.

According to the Greek historian Herodotus, the first person to successfully predict a solar eclipse was the Greek philosopher Thales of Miletus in 585 BCE, with the resulting celestial event ending a half-decade-long war.

Ancient Egyptians played Senet, a board game where players threw sticks or bones as dice.

An analysis of ancient texts found that dementia was rare in ancient Greece.

Exposing fetuses to certain flavors in the womb could lead to children being less picky eaters

A new study found that 3-year-olds were less averse to the smell of vegetables they had been repeatedly exposed to in utero, suggesting that what mothers eat in late pregnancy can leave a lasting imprint on their children's tastes.

Before alarm clocks, people relied more heavily on their circadian rhythms, humans hired to wake them, and on tools such as candle clocks that dropped pins in metal trays at roughly set intervals.

Without mummies, ancient Egyptians feared their souls would perish

The ancient Egyptians placed major importance on mummification because of their beliefs about the afterlife. They believed a preserved body was essential for the soul’s survival, as it needed a physical form to return to. Without it, they feared the soul would perish.

The ancient Egyptians built prototypes of the modern Suez Canal

The idea to facilitate trade between the Mediterranean Sea and the Red Sea and connect the Eurasian continent was apparent even to pharaohs in the second millennium BCE. Though no physical traces remain, contemporary accounts attest to early, shorter versions of the canal, including from Herodotus.

Calculate your chance of success for IVF treatments

The efficacy of in vitro fertilization procedures varies widely based on age, health history, genetics, and more. This CDC calculator provides an estimate of success rates based on your personal information, relying on thousands of reported outcomes across the US.

Scientific advances are unlocking a wide range of alternatives to IVF

From refined artificial insemination and microsurgical sperm extraction to experimental uterine transplants, scientific innovation is rapidly advancing potential fertilization technologies. But they come along with costly trials, some ethical dilemmas, regulatory issues, and more.

A new AI-assisted reproductive technique is finding 'hidden' sperm cells for those with very low sperm counts

Known as the Star system—for Sperm Track and Recovery—it uses artificial intelligence to help identify and locate "hidden" sperm in men with a rare infertility condition called azoospermia. The condition affects about 1% of men, and these individuals have sperm counts low enough that the individual spermatozoa in their ejaculate may be undetectable. In late 2025, the first baby was born after the child's parents used this assistive technique to locate sperm.

Wealthy Egyptians slept on woven beds to allow air circulation in hot climates

The history of beds is a fascinating look at economics, social science, and cultural beliefs around what takes place during sleep. This brief survey of the history of bed-making begins roughly 5,000 years ago and runs through ancient Egypt and Rome to modern Europe. Take a look here.

Researchers once thought Stonehenge functioned as a precise astronomical computer

In the 1960s, scientists used early computers to analyze the stone layout at Stonehenge, arguing it could predict eclipses and other celestial events. This BBC Sky at Night Magazine piece explains how the theory arose—and why scholars now doubt it.

When did people start making and using glass?

This article details the search for the ancient origins of glass, a now-common item through which archaeologists can spot histories of trade and innovation. Bronze Age glass was made from crushed quartz instead of sand, and artisans could color glass with materials such as cobalt. These trace metallic add-ons have given scientists a vital clue into the origins of glass, which is currently debated as either Egypt or the Near East.

Scientists are reconstructing ancient smells—including a 3,500-year-old ancient Egyptian mummy

Researchers explain how they have recreated the scent of ancient Egyptian mummies and enabled museum-goers to experience that scent on specialized cards. The exhibit will be at the Royal BC Museum in Canada in June 2026.

An Egyptologist answers questions from the internet

Professor of Egyptology and Archaeology Laurel Bestock answers your questions about ancient Egypt from X. What did ancient Egyptians sound like? Why is King Tut so enduringly popular? What ancient Egyptian medicine and tools do we still use in modern times?

Aurea is the first US baby born following polygenic analysis

The child, born in May 2020, was selected by her parents to optimize for certain health qualities based on an analysis of her multifactorial genes by a New Jersey-based company called Genomic Prediction. Her embryo was selected for implantation based on polygenic risk scores for heart disease, diabetes, and cancer.

Why humans evolved single-child pregnancies

While birthing twins has been a rare occurrence for humans, research suggests that twins were actually the norm much further back in primate evolution. It’s proposed that single-childbearing turned out to be critical for the evolution of larger babies with larger heads. Discover more about the shift that gives insight into primate evolution.

The Rosetta Stone praised the Pharoah Ptolemy V in the 196 BCE

Since its discovery in 1799, 27 other copies have been found throughout Egypt, the most recent in 2011. Dr. Ilona Regulski, curator of ancient writing at the British Museum, discusses the crucial artifact and its specific content.

Four astronomical discoveries from ancient Greece

Modern astronomy relies on making discoveries without being present on the planets, stars, galaxies, and other objects studied. Imagine the difficulty the ancient Greeks had studying them without computers and telescopes. Yet somehow they calculated precise measurements of planetary distances, sizes, and more. Read this page to learn more about early triumphs in astronomical science.

Nail art can be traced back to 5,000 BCE

Archaeologists discovered Egyptian mummies with nail art and henna-tinted fingertips. The trend would continue informally for centuries until Revlon introduced modern nail polish in 1932.