An analysis of ancient texts found that dementia was rare in ancient Greece.

How reading and writing can lower dementia risk by almost 40%

Research published in 2026 that tracked almost 2,000 older adults for an average of nearly eight years suggests that lifelong exposure to intellectual stimulation, such as learning a language, reading, and writing, can lower dementia risk by as much as 40%.

Millions of aging Americans are facing dementia or cognitive impairment—alone

An estimated 4.3 million people aged 55 or older who have cognitive impairment or dementia live alone in the US. The individuals facing these challenges are more likely to be women, people of color, and to generally be poorer and less educated than other older adults who are also living alone.

Brain training game creates long-lasting changes in the brain that may help protect against dementia.

Explore this 1440 Original video offering a primer on Alzheimer's disease and what's known about its incidence, causes, and more.

Alzheimer's disease is the leading cause of dementia and risks rise after age 65

Read this primer about Alzheimer's disease and learn what factors increase the risk of this form of dementia, including genetics, being a woman, and health conditions, including high blood pressure.

Ultraprocessed foods are linked with a 58% elevated risk of developing dementia.

Some dementia cases may be linked to treatable microorganism infections in the brain.

Learn the differences between mild cognitive impairment and age-associated memory loss

Mild cognitive impairment is a condition in which people experience more thinking and memory problems than expected for their age. It's often associated with depression and anxiety. Daily routines, writing things down, and healthy lifestyle choices can help cope with the condition, but there's no cure. The condition elevates the risk of developing dementia and Alzheimer's.

America's financial burden from dementia in 2025 was $781 billion

That figure, calculated by researchers at the University of Southern California, includes medical and long-term care costs, unpaid family and friend caretaking, lost productivity for patients and their families, and the economic loss in quality of life for patients and their families. In 2025, they estimate there were 5.6 million people living with dementia.

Neurodegeneration is the process underlying dementia, but it may happen for myriad reasons, and its triggers are under investigation.

Five to ten percent of Alzheimer's cases are early-onset

Early-onset Alzheimer’s typically emerges around 40 to 50 years of age, with devastating effects. This video follows Brian, diagnosed with the disease at age 54, as he travels the country as an advocate for research and discusses the progressive mental fog of Alzheimer’s.

Alzheimer's brain changes may begin years before symptoms appear.

GLP-1s may lower inflammation, possibly helping to combat cognitive decline

An analysis of existing GLP-1 research, published in April 2025, indicated that GLP-1 drugs reduce inflammation, with numerous health benefits. The work notes that GLP-1s were linked with a statistically significant reduction in dementia in randomized clinical trials.

Can your identity be preserved amid dementia?

Memory loss associated with progressive dementia raises questions about whether a person's identity can be maintained during the disease's progression. One outlook suggests we define ourselves by our social relationships—offering a potentially more humane approach to caring for those with dementia.

Can humans delay or reverse old age?

We're not sure yet. Researchers at the University of California San Francisco are studying why some conditions and behaviors, such as low-oxygen environments and exercise, benefit the aging process, hoping to reveal potential health applications. Some of this research focuses on klotho, a naturally occurring age-regulating hormone named after the Greek Fate Clotho. Animal studies on klotho brain injections found subjects had improved memory recall and age-related degeneration resistance.

How do 'dementia villages' work?

The goal of good dementia care is to preserve a patient's quality of life as the incurable disease progresses, maximizing their ability to lead normal lives and maintain their health and dignity. Dementia villages are small neighborhoods built for people with severe dementia, with typical neighborhood haunts like salons or grocery stores staffed by people trained in dementia care, helping residents maintain a sense of autonomy and connection.

Sitting 10+ hours per day increases dementia risk

People who sit for at least 10 hours per day are more likely to develop dementia, according to a study published in 2023. This article details the study on the murky relationship between brain health and prolonged sitting. This study involved...

Untreated hearing loss is linked with dementia risk

Hearing loss does not cause dementia, but it does increase the risk of developing dementia and research suggests that people who wear hearing aids for age-related hearing loss also maintain better brain function than those who don't.

Dementia caregiver training programs exist—but they aren't common

Comprehensive dementia care programs go beyond offering support to caregivers. They train people on how to modify their homes, communicate with their loved ones with dementia, and cope with the stress of caregiving, among other skills. Yet despite evidence showing their effectiveness and the economic benefit of avoiding unnecessary emergency room visits, these programs are often poorly funded and difficult to find.

The first identification of Alzheimer's was made in 1906.

Memory disorders disrupt the brain's ability to make, store, or recall memories

These disorders stem from reversible issues like vitamin deficiencies or irreversible causes such as stroke or dementia. Only one type of dementia—familial Alzheimer’s disease—is directly inherited and accounts for about 20% of Alzheimer’s cases.

Read the original 1907 paper on the first known Alzheimer's patient, which was identified by Dr. Alois Alzheimer.

Dementia describes progressive memory issues that impact daily activities

Although Alzheimer's disease is sometimes thought of synonymously with dementia, there are multiple types of dementia, which manifest in memory loss and other symptoms that make it challenging to perform daily tasks. These types include Lewy Body dementia, vascular dementia, and frontotemporal dementia. Parkinson's disease is not a form of dementia, but this movement disorder can sometimes develop into issues with memory and a formal diagnosis of dementia.

One biologist is leading the blue zone criticisms—both questioning the original recordkeeping for these purported longevity-prone locations and pointing to recent research showing declining numbers of healthy seniors in several official blue zone regions.

Ancient Greece originated roughly 4,000 years ago around the Aegean Sea, and over centuries expanded as far as Spain and India.

Taxi and ambulance drivers appear to have the lowest risk of dying from Alzheimer's disease out of 443 occupations, which suggests that constant real-time navigation work strengthens the hippocampus and may help protect against the disease.

Does our fear of Alzheimer's create stigma around its treatment?

Surveys suggest our fear of Alzheimer's as a disease outranks that of heart disease and cancer. This piece argues our fear of aging and the slipping away of our mental capacities make it more difficult to treat Alzheimer's compassionately.

Retired professional soccer players are showing signs of potential neurological impacts in midlife, according to a study presented at the July 2026 Alzheimer's Association International Conference in London.

Early-onset Alzheimer's can appear as early as age 30, but estimates of its prevalence remain uncertain.

How family members disappeared into dementia

This narrative feature describes one family's troubling experience with frontotemporal dementia, or FTD, which emerges in the prime of adult life — as young as 40, in some cases — and degrades the brain's ability to plan, organize, express language, understand social cues, and exercise judgment.

Pets of ancient Greece: crickets and ferrets and hedgehogs, oh my!

Ancient Greece left behind literature and art in which geese, doves, dogs, and the like are seen keeping people company or holding vigil for their return. Were these considered pets as we understand the term today, and where did ancient Greeks fall on the timeless question of cats versus dogs? Did Odysseus let Argos onto the sofa? This magazine article explores evidence of pets and their treatment in ancient Greece.

Super-agers: seniors 80 and above with the memory ability of people in their 50s

Studies show the number one indicator of whether someone is a "super-ager" is not diet or genetics, but the extent of their social relationships. Moreover, scans reveal noticeable physical differences in certain parts of the brain in patients with extensive social networks.

Read the main paper criticizing the concept of blue zones, which argues recordkeeping errors, pension fraud, and natural disasters likely explain the high numbers of purported healthy centenarians in certain locations.

The color blue is almost never mentioned in ancient Greek literature

Linguists have noted blue is regularly the last color to enter the language of most cultures. Researchers guess that the color's rarity in living organisms is partly the cause of its linguistic absence.

The formula behind super agers—those possessing health and cognitive skills of people decades younger

A study of about 1,400 super agers did not identify any underlying genetic mechanism for longevity. While researchers instead emphasized that sustainable habits involving positive social connections, sleep, mood, diet, exercise, and personal fulfillment help reduce long-term risks, there is no one-size-fits-all formula for everyone.

Hearing loss is linked with brain volume reductions

The brain looks different as a result of hearing loss, with reductions in brain volume overall and in specific areas, and these changes are hypothesized to impact cognition. Exactly why hearing loss alters cognition is an active area of research, but theories include that the elevated cognitive load of straining to hear affects brain power available for thinking and memory and that hearing loss leads to social isolation which boosts dementia risk.

Why vascular dementia develops

This type of dementia, the second most common form after Alzheimer's, develops due to microscopic bleeds and blood vessel blockages in the brain. The condition isn't curable but medications to help with blood clotting and high blood pressure are part of a suite of interventions designed to minimize damage to the brain.

Ancient ghost stories appeared in texts like 'The Odyssey'

Sharing ghost tales has been around for centuries. Ancient Mesopotamia, Rome, and Greece each had their own chilling stories about encountering spirits. Find mentions of specters in some of history’s most famous writings like the "Epic of Gilgamesh" and "The Odyssey."

How aging degrades neural functioning in the brain over time

Aging affects the brain perhaps more than any other organ in the body. Throughout life, the brain experiences radical shifts in the number of neurons, synaptic connections between neurons, and hormone levels that regulate our mood and processing.

Medical recognition of strokes stretches back to ancient Greece

Every minute, 750 milliliters of blood flows to the brain, supplying 20% of the body’s oxygen. A sudden disruption—whether from a clot (ischemic stroke) or a bleed (hemorrhagic stroke)—can be life-threatening. From ancient Greek theories to modern CT and MRI scans, here’s how stroke science has evolved over time.

After a dementia diagnosis, it's important to plan ahead but also savor the moment

The next steps after a diagnosis include taking lifestyle steps to slow disease progression and completing legal paperwork about long-term medical preferences. It's also important to appreciate the moments and days ahead and find humor in them, when possible. (Some users may encounter a paywall.)

Child mortality rates since ancient Rome

One of the great achievements of modern humanity has been the sea change in child mortality rates—the chance that a newborn eventually lives past puberty. For thousands of years, children had a 50% chance of not entering adulthood. About 300 years...

In the original 2004 blue zones study, which sought to verify the ages of long-lived, healthy populations in Sardinia, Italy, researchers hypothesized that inbreeding in these isolated communities may have helped promote their longevity.

MS Drugs reduce inflammation, helping reduce relapses and slow disease progression

Disease-Modifying Drugs calm the body's inflammatory response to help stave off relapses—when new or existing MS symptoms show up for a day or longer. Avoiding smoking, exercising, reducing stress via mindfulness, checking for vitamin D deficiencies, drinking more water and eating well, all can slow disease progression. [The jury's still out on if HRT around the time of menopause may reduce dementia risk](https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(25)00122-9/fulltext) Estrogen can reduce inflammation and support neural growth in the brain, and some research has suggested that beginning hormone replacement therapy around menopause—versus later in life—reduces Alzheimer's disease risk. Still, a recent systematic review concluded that taking HRT didn't affect dementia risk, regardless of when women started taking it, so the science remains unsettled.

Alzheimer's can cause significant brain shrinkage in the affected brain regions, including the hippocampus.

Alzheimer's in the United States is most prevalent in the South and the East.

The Greeks weightlifted using massive stones and admired strength—but they viewed muscles differently

Why human brains were bigger 3,000 years ago

Our modern civilisation may be the most advanced to ever exist on Earth, but around 100 generations ago, our ancestors had brains that were larger than our own.

Scientists are reevaluating the causes of Alzheimer's beyond the amyloid hypothesis after numerous experimental drugs designed to target that theory have failed.

A timeline of the ancient Greeks

When exactly were the Ancient Greeks around on Earth? Their roots go back nearly 9,000 years to the Bronze Age with the so-called Minoan civilization. These sea-faring tribes would come together to hold off the invading Persian Empire and culminate in the glories of Athenian democracy, Spartan military discipline, and more. Check out this thorough timeline of the Ancient Greeks.