The science of spring fever

The science of springtime, 101

Dive into the basics on springtime including the astronomy that brings it about, natural signs of spring's arrival, and some of the cultural approaches to the season.

Love and heartbreak trigger powerful, neurochemical-driven changes in the body

The feeling of falling in love floods the brain with dopamine, oxytocin and serotonin, which collectively dull pain and boost immunity. However, the loss of these chemicals during a break-up produces withdrawal-like symptoms and heart issues, such as high blood pressure.

Twelve ways the world celebrates springtime

Celebrating the seasonal change is rarely filled with as much relief and hope around the world as spring. This list compiles some famous and lesser-known springtime traditions from diverse cultures.

The side effects of falling back and springing forward

Daylight saving time can interfere with a person’s sleep schedule, but it also has been linked to increased rates of depression, heart attack, stroke, cancer, and car accidents. UT Southwestern’s Dr. Joseph Takahashi explains why the time change is bad for your brain and health.

Goose bumps are often triggered by emotions

A physiologist and professor of zoology explains that the subconscious release of adrenaline, a stress hormone, causes a contraction of skin muscles. It’s released in several situations, including when humans are cold, afraid, or feel strong emotions. (Some readers may experience a paywall.)

10 percent of SAD cases occur in the summer

Despite its significantly lower incidence, summer-risk SAD is as significant as its winter counterpart. Rather than being prompted by less light, the summer version is typically spurred by high temperatures, strong light, distinct summer time social pressures (appearing in a bathing suit, for example), and pollen. Common treatments include keeping cool and prioritizing sleep.

Women are four times as likely to be diagnosed with seasonal depression

This prevalence trend mirrors the broader incidence of depression among women and is well-documented. Researchers suggest the disparity stems from differences in hormones, social role expectations, coping mechanisms, and more. Men may also present with depression differently, and seek help less.

An engineer tracked his moods for decades and helped researchers identify SAD

Civil engineer Herb Kern had bipolar and would record his moods dating back to 1967. He noticed the seasons were a major factor in the increase and severity of his episodes. By reaching out to researchers at the National Institute of Mental Health, Kern became the first human to confirm increased melatonin levels during winter and to receive bright light therapy.

Fear (and stress) can be contagious via pheromones secreted by the body

While seeing someone else in a panicked state may induce a stress response, researchers have found stress can be literally contagious—chemicals contained in sweat and other secretions can trigger stress hormone release in others. Theories suggest this feature is an evolutionary adaptation to protect groups from danger.

Researchers are studying roller coasters to improve mental health treatments

Scary rides stimulate our fight-or-flight response while simultaneously releasing feel-good endorphins like dopamine, serotonin, and oxytocin. Once we realize we're in a safe space, we can enjoy the ride and even feel confident and relieved by the accomplishment of overcoming a fearful feat.

SAD 101 from the folks at NIMH—where the condition was first identified

Norman Rosenthal led the team at the National Institute of Mental Health that first identified and described seasonal affective disorder in 1984. This 101 from NIMH explores the basics of the condition, from who develops it to how it is treated.

Stress can be contagious—and scientists want to learn more about it

Researchers have shown that being around someone who is stressed can trigger a stress response in your body, such as elevated cortisol levels and elevated heart rate. One way this was recently studied was by having people watch stressful activities, like a recorded job interview or solving challenging math problems, and then sampling hormones in observers' spit.

Even brief physical activity can trigger the release of neurotransmitters that provide mental health boosts.

One theory claims the retinae of SAD patients may fail to adjust to less light in winter

Most people’s eyes become more sensitive to light in the winter months, but some do not. This failure to adjust causes ripple effects on those individuals’ biological clocks. This Ted-ED video provides a clear, brief, narrative explanation of the condition in six minutes.

How menopause affects mental health

Menopause, a natural biological process, occurs in three stages: perimenopause (hormone fluctuations), menopause (end of menstrual cycles), and postmenopause (12 months without menstruation). Hormonal shifts during this time can affect neurotransmitters, increasing the risk of mood disorders.

The hormone that spreads love and helps fish share fear

Scientists consider emotions like fear and empathy to be among the oldest evolutionary behaviors observed in mammals. Yet to date, how these reactions are processed in the brain, regardless of species, is not well understood. A new study reveals how the chemical oxytocin—known as the "love hormone" in humans—helps let fish know when their friends are in danger.

The brains of people who experience frisson have unique neural pathways

A small 2016 study aimed to investigate the behavioral and neural differences between 10 individuals who experience goose bumps when listening to music and 10 who typically don’t. Scientists reported that individuals experiencing musical chills had greater white matter connectivity in specific auditory, emotional, and social processing areas of the brain.

Read Norman Rosenthal’s original 1984 paper describing SAD

The study helped formalize research and diagnosis of seasonal affective disorder, catalyzing the development of therapies (like bright light) and leading to broader adoption of effective treatments. It also helped connect the influence of light and seasons on biological mechanisms in the human body, spurring exploration of circadian rhythms.

Norman Rosenthal’s struggle with SAD inspired him to understand it

The South African doctor migrated to New York City in the 1970s. During his first winter there, he noticed the shorter days had a significant impact on his mood compared to those in his hometown of Johannesburg, South Africa, which is much closer to the equator. After three years of this seasonal mood shift, he decided to focus his studies. Hear him speak in this quick narration.

The hidden effects of March Madness

March Madness isn’t just a major sporting event—it’s also peak season for vasectomies. Urologists report a 50% increase during the tournament, as patients use recovery time as an excuse to watch nonstop basketball. Meanwhile, workplace distractions from bracket pools and game streaming are estimated to cost US businesses $17 billion.

Some data shows cold showers can help with depression

An icy water exposure can lead to the release of norepinephrine, cortisol, dopamine, and other stress hormones that are beneficial, among other potential effects. Some data shows that this type of exposure can help combat depression symptoms among some patients, but more research is still needed. (Some users may encounter a paywall.)

How we frame stress—as good or bad—seems to alter how it affects us

This podcast discusses research that indicates stress perception may drastically affect how we respond to it. In research exploring if our stress is presented as diminishing our health versus if we're told it enhances our performance, it will lead to differences in how successful participants are at performing tasks—with the enhancers doing better.

Too little stress can also harm our health because mild or moderate stress—followed by recovery—helps make us resilient.

Four psychological tools for a happier, calmer life

The perennial debate on how to be happy involves various aspects of life, and one of the most essential is our psychological attitudes toward experiences. This piece lists and explains four basic tools to strengthen your "psychological immune...

Music may give some of us the chills and goose bumps—perhaps because it shocks us

The science is still unsettled about why music can trigger a chill down your spine, formally known as frisson, but one theory is that anything surprising to the nervous system—including sudden beat drops or unexpected harmonies—stimulates a type of alarm response that gives rise to this feeling.

The biology of stress in your body

Stress is a normal human response that has evolved over millions of years to handle changes or threats in our environment. This article is a helpful overview of the biological basics of this response. While it is not harmful to our physiology in the acute setting, chronic stress can lead to damaging changes in the human body over many years.

How science explains déjà vu

Take a fun look at the science explaining the odd experience of déjà vu, which some theories suggest is actually a sign of a healthy brain.

Humans are wired to pick up on each other's emotion, making laughter contagious

The reaction plays a key role in establishing interpersonal connections and relieving stress by releasing endorphins—feel-good hormones. A 2021 study identified at least 65 animal species that produce playful sounds, such as laughter.

Our ancient fight-or-flight response may contribute to modern ailments

Many common modern diseases humans struggle with may in fact have their origins in our ancient fight-or-flight stress response. Long-term effects of the stress hormones cortisol and adrenaline—in this case, triggered by things like workplace stressors—can wreak havoc on the delicate internal balance of our organ systems.

The emotional regression that happens when we visit home

Despite how mature we might like to think we are, returning home for the holidays often results in reverting to our moodier, angstier childhood selves. This story in the conversation dives into the root of this phenomenon, which can largely be explained by attachment theory. Read along to understand how your past experiences and attachment style can influence your current behaviors and for advice on how to cope with regression.

The positives of feeling stressed

Worrying about past events and upcoming challenges is not a pleasant experience, but a reasonable amount of stress can bring a lot of good into our lives. In this episode of "The Happiness Lab" with Dr. Laurie Santos, two psychology experts offer tips for resetting one's relationship with stress. Listen and learn how to make stress a positive tool rather than a debilitating emotion.

There’s a psychological explanation for ‘FOMO,’ or the fear of missing out

This video breaks down FOMO—what it is, how it works, and why it happens—showing how social comparison and uncertainty trigger anxiety that pushes people toward risk-taking and constant checking behaviors.

Some of us can control our goose bumps

A small 2018 study examined the rare ability to control goose bumps. Researchers found some intriguing associations between having a particularly open and curious personality type and the ability to trigger this sensation—a link that they hope will be explored further in the future.

Fearology, or the study of fear, explores the difference between stress and fear

Our brains involuntarily respond to our environment and signal alarm when that isn't always needed, triggering responses that include goose bumps. But understanding fear and how to talk our brains into calming down can improve daily life.

Daylight Saving Time is linked to a rise in heart attacks and strokes

Losing an hour of sleep with seasonal time changes is not good for our health and it’s linked to risks for the first couple days of Daylight Saving Time, including a short-term rise in heart attacks and strokes. Scientists theorize these elevated risks are linked to the disruption to the body’s circadian rhythm.

JJ Schildkraut theorized depression is linked to brain chemical imbalances—in 1965

Schildkraut was one of the first to put forward this idea, which stemmed from lab animal research. A decade later, researchers published the first landmark paper on fluoxetine—better known by trade name Prozac—which increases serotonin levels in the brain.

How brain cells carry information

At any moment, there is an electrical storm coursing through your body. Discover how chemical reactions create an electric current that drives our responses to everything from hot pans to a mother’s caress.

Menopause and perimenopause symptoms may affect both the mind and the body

Women going through these aging transitions may experience some common physical and mental symptoms to varying degrees, including hot flashes, bladder control issues, brain fog, and vaginal dryness. This article dives into some of the most common symptoms women might expect during perimenopause, plus what they can do to relieve them.

50 years of research has focused on unraveling the relationship between music and frisson

One insight reveals that musical passages with surprising volume changes or unexpected harmonies and beauty are more likely to trigger frisson, perhaps because they upend listeners' expectations.

Meteorological v. astronomical seasons, explained

Meteorologists and climatologists define seasons differently from “regular” or astronomical spring, summer, fall, and winter. Traditional seasons reflect the movement of celestial objects, known as the astronomical seasons; meteorologists mark seasonal change based on temperature averages.

SAD disrupts melatonin secretion, producing it longer in the morning

The hormone is secreted from the pineal gland in the brain and is key to the timing of sleep. However, the substance does not generate sleep itself. With seasonal affective disorder, the body misperceives the photoperiod—the time with light—and the cycle of sleeping and waking gets off-phase, leading to issues with circadian rhythms.

How to think yourself into health

Can the right thoughts lead to a stronger immune system? Neuroimmunologists like Hai Qi study how drugs targeting the brain, as well as thought exercises, can prompt stronger immune responses to infection. This six-minute video investigates the radical claims.

The science of fear

The Hidden Brain podcast team explores the science of fear by traveling to a haunted house curated by a scientist to investigate what scares us, and why some people enjoy this sensation more than others.

The neuroscience of heartbreak

An analysis of functional MRIs revealed a difficult fact: the active brain areas of people experiencing heartbreak were very similar to those actively in love. This is a major reason why people in the middle of rejection can't accept the reality of their loss. This article breaks down the various changes in neurotransmitters and neural pathways for those enduring that universal experience, heartbreak.

How to cope with postvacation blues

While it might seem counterintuitive, new research shows that experiencing exhaustion or a lack of motivation postvacation is fairly common. While travel itself can, of course, be tiring, the contrast between vacation freedom and endless Slack messages can be even more so. This article explores why the return-to-work existential crisis happens, and offers advice for beating the post-vaycay blues. Read it here.

Lack of sunlight during Arctic winters can fuel a winter slump and a circadian disconnect.

Cold water swimming can induce positive stress

The tradition of cold water swimming (or taking a cold plunge, or even a cold shower) has been shown to release the same hormones triggered during a stress response. This can have the effect of increasing blood flow, improved mental acuity, and more.

Roughly 10% of the world has SSAD—SAD’s milder, nonclinical cousin

Subsyndromal affective disorder is diagnosed when someone exhibits two of the nine major criteria for depression (but not more than five) as a result of seasonal changes. While it is milder than primary SAD, SSAD is still significant and impacts millions.

Environmental conditions, shifting immunity, and viral strain could help explain 2025 spike

The surge in HFMD in the summer and early fall of 2025 in the mid-Atlantic could be the result of a confluence of factors, including a more virulent strain of disease-causing virus, good environmental conditions for the virus to spread—hot, humd—and a potential immunity gap among kids due to milder HFMD outbreaks the previous year.

Extreme heat is neurologically impairing animals

Dog bites increase in summer, birds struggle to learn, and goats pick more fights. Scientists are unraveling new details about how heat impairs animals' neurological systems.