Heatstroke treatment guidelines were built almost exclusively on research in men

Reduced inflammation from cold plunges lacks scientific support

The cold water triggers immediate cold shock, increasing heart rate and blood pressure, and prolonged exposure can lead to cold-water incapacitation and hypothermia. Plungers are encouraged to enter the water slowly and manage their breathing to reduce the risk of shock. Warm baths post-plunge are discouraged, and exercise is generally better for recovery.

Heatstroke occurs when the body reaches 104°F or higher and can't cool itself

Untreated, this medical emergency can result in permanent disability or death. Someone suffering from heatstroke—defined as a core temperature of 104 degrees Fahrenheit but sometimes as high as 106 degrees Fahrenheit—may appear confused and require immediate cooling, ideally with an ice bath.

Heatstroke is sometimes missed because the patient is really sweaty

Since the condition involves losing the ability to cool oneself, clinicians sometimes see someone who has exertional heatstroke—like a high school athlete who is really sweaty—and don't realize the heat-related illness has already progressed to heatstroke. Classic heatstroke typically occurs among the very young or the elderly. (Some users may encounter a paywall.)

Health workers may cool body temperatures with convection cooling

That's spraying a patient with water and putting fans over them. Cooling the body by removing clothing and placing cold water and ice packs—and not blocking evaporation—are essential cooling steps.

Heatstroke is when the body's core temperature becomes dangerously high—and needs to cool

Warning signs that the body is overheating include rapid breathing, cramps, heavy sweating, nausea, and feeling lightheaded. Drinking plenty of fluids, seeking shade, and cooling the body down as quickly as possible with icepacks can help reduce the risk of heatstroke.

Exertional heatstroke is a leading cause of death among athletes and soldiers in training, and typically occurs when someone sweats intensely while exercising in the heat.

Heatstroke deaths may be massively undercounted—perhaps by a factor of 10

One often-cited average estimate of annual American heat deaths—roughly 1,200 per year—is based on death certificate data, but it may be a significant undercount because heat kills through cardiovascular, kidney, and respiratory causes that are more likely to be cited on those documents. (Separate analysis that looked at data from 1999 to 2023 found that the highest number, in 2023, was 2325.)

Heatstroke—from overexertion or extreme heat—drives core body temperature to 104 degrees Fahrenheit or higher, setting off a cascade of problems in the body.

Korey Stringer, of the Minnesota Vikings, died of heat-related illness in 2001

In response, the NFL overhauled its heat approach and no other player has since died from heat-related illness. Even at the high school level, research suggests safety measures should include: mandating water breaks, keeping a cool tub available, and having athletes acclimate to high-temperature playing conditions for a week or longer before donning the full set of protective equipment.

Some research suggests that the gut microbiome influences our risk of heatstroke, with elevated exercise levels raising body temperature to unsafe levels and increasing gut permeability—causing a "leaky" gut.

Heatstroke can reprogram your DNA, putting survivors at risk of future health problems.

86 commonly used drugs, including certain antidepressants, painkillers, and immunosuppressants, have different results for men and women, according to recent research.

Supplements ahead of exertional heatstroke helped protect mice against brain damage

In the lab, mice dosed with probiotics prior to inducing exertional heatstroke, had better cognitive outcomes. This evidence underscores the links between the gut microbiome and the brain, at least in rodents.

Heat-related complications are of greater concern for distance runners than cardiac threats

Analysis of more than 130,000 runners in Tel Aviv events during a seven-year period indicated that the runners were 10 times more likely to experience heatstroke than serious cardiac problems. Scientists suggest that runners should take 10 to 14 days to acclimate to a hot climate before tackling a serious run.

67 US high school athletes died from exertional heatstroke between 1982 and 2022

Many of those deaths were from football specifically, where student athletes play in hot conditions while wearing heavy protective gear. Few states mandate heat guidelines for school athletes, and this article says that's of increasing concern with more high heat index days.

Certain medications that affect blood flow or mood boost the risk of heatstroke

Drugs that narrow blood vessels, beta blockers that regulate blood pressure, diuretics, antidepressants, and antipsychotics can all affect the body's ability to regulate its internal body temperature, and so individuals taking these medications need to take special care in extreme heat and when exercising in hot conditions.

Cold water swimming can induce positive stress

The tradition of cold water swimming (or taking a cold plunge, or even a cold shower) has been shown to release the same hormones triggered during a stress response. This can have the effect of increasing blood flow, improved mental acuity, and more.

Heat exhaustion is the most likely diagnosis if someone is talking clearly

Heatstroke, true to its name, looks more like a stroke. Its symptoms include severe disorientation, irritability, and seizures, among others. A patient does not need to have collapsed in order to have exertional heatstroke, but if someone is talking clearly, they likely have heat exhaustion, and it hasn't progressed to heatstroke.

How to survive hypothermia

Hypothermia is a deadly risk for those living in cold areas, causing around 1,500 deaths a year in the United States. Stay safe with tips from this article, which cites research papers to help prevent and treat the condition. Take note of the best fabric to wear when cold weather hits—not cotton but wool.

Heat-related deaths may have climbed by more than 50% over 20 years

Between 2000 and 2009 one study suggests annual heat deaths averaged around 2,670, but between 2010 and 2020 that figure was likely more than 4,000. Researchers studied 54 million death records from the contiguous US and created mathematical models to arrive at these figures, noting that a combination of aging populations and climate change drove that increase.

Extreme heat puts people at risk of developing kidney stones

It's essential to remain hydrated in summer weather to keep your body healthy, but one reason is to help dilute minerals that naturally build up if they aren't excreted in our water-fueled urine. Doctors recommend people generally drink 64 ounces of water a day and also eat foods with salt to help ward off dehydration.

13 unconventional ways to stay cool during heat waves

While air conditioning is the default solution for many in a heat wave, it can get expensive while requiring the consumption of fossil fuel energy. So, how else can you stay cool during a heat wave? This list compiles some practical, at times quirky, suggestions, including an ice-pack-filled aubergine hat.

Some data shows cold showers can help with depression

An icy water exposure can lead to the release of norepinephrine, cortisol, dopamine, and other stress hormones that are beneficial, among other potential effects. Some data shows that this type of exposure can help combat depression symptoms among some patients, but more research is still needed. (Some users may encounter a paywall.)

Sickle cell trait can put people at elevated risk of heat-related illness

This hereditary blood disorder affects the shape and function of red blood cells. A US military study found that among recruits the incidence rate of exertional heat-related illness was 48% higher among those who had sickle cell trait as compared to those without. Easing into intense exercise and gradually increasing exertional frequency and intensity is recommended.

Our bodies cool us down by sweating because water requires a significant amount of energy to change state from liquid to gas, making it an ideal medium for carrying thermal energy away from our bodies.

Within months of a landmark 2002 study that indicated HRT harms, sales dropped by about half

In the early 2000s, Women's Health Initiative studies indicated HRT increased risk of breast cancer, heart disease, and stroke in some women—so many physicians stopped prescribing it to help with menopause symptoms. But further research has concluded that much of the elevated risk was overblown and that it was also disproportionately seen in women in their 70s who had been taking an older HRT formulation.

Extreme heat is neurologically impairing animals

Dog bites increase in summer, birds struggle to learn, and goats pick more fights. Scientists are unraveling new details about how heat impairs animals' neurological systems.

The gaps in menopause research and their effects

Nearly all studies (99%) researching the biology of aging don’t consider menopause in their setup. A Harvard professor noted that about 75% of aging-related diseases are likely influenced by menopause. In this article, she discusses how gaps in research are negatively impacting how the medical system can effectively treat aging women. Read her analysis of the issue here.

Headache disorders have historically been neglected and under-researched

Confusion between the variety of headaches—from mild discomfort to debilitating pain—and gender bias—migraines primarily affect women—have led to widespread misunderstandings of the medical issue. Medical students in the US may get as little as 30 minutes of instruction on the three major types: migraines, cluster headaches, and tension-type headaches.

Women's health research continues to be underfunded

Health conditions that affect women more than men get less research funding. This interactive collection of graphs details the gendered gap in health research funding. Of the conditions that affect one sex more than another, those that create the...

Extreme temperature resilience appears to be temporary for tardigrades

Although often considered indestructible, scientists observed these creatures could endure temperatures near 150°C for only a few minutes in their tun state. Outside this state, only half the samples in a Danish study survived 37.1 degrees Celsius (98 degrees Fahrenheit) for 24 hours, making tardigrades extremotolerant rather than extremophiles.

Less than 1% of aging studies consider menopause and its effects

Nearly all studies researching the biology of aging don't consider menopause in their setup. In part, that's because menopause is difficult to emulate in animal models. Menopause is uncommon in the animal world beyond humans and whales. This presents a problem for medicine and science because about 75% of aging-related diseases are likely influenced by menopause.

HRT for menopause may not help with mental health or sleep says a large 2026 analysis

A recent analysis investigating the effects of menopause and HRT use on mental health, cognition, and brain health suggested HRT did little or nothing to aid with mental health and sleep. But the researchers caution that, among other data gaps, they didn't have information on which HRT formulations were used among their nearly 125,000 participants, so results may have varied by drug treatment.

Under certain conditions, very hot liquids can freeze more quickly than cooler ones—a phenomenon called the Mbemba effect, after the Tanzanian high school student who accidentally observed it.

Hundreds of vulnerable Chicago residents died in 1995 during a long-lasting heat wave

Eric Klinenberg wrote a book diving into the specifics of the heat wave. His book, detailing the stories and context fueling more than 700 deaths during just one summer week, helps readers understand how social infrastructure lapses, power outages, and ineffective heat responses led to so many deaths.

Normal body temperature varies from one person to another; it's not uniformly 98.6 F, as physician Carl Wunderlich determined in the 1800s.

Cold-blooded reptiles seek heat, and that behavior may help combat fungal infections

This Radiolab podcast episode takes on the idea that though our human bodies are too warm for the majority of fungal species to effectively replicate inside our bodies, that's not the case for reptiles. Yet when those species warm their bodies by basking in the sun on rocks, they can soak up heat and may also help keep fungal infections in check.

Schizophrenia increases heat death risks in several complex ways

Evidence shows that people with schizophrenia have an inherently harder time regulating internal body temperatures. They may also struggle to find safe shelter during extreme heat, and their prescribed antipsychotic medications often have dehydrating effects, collectively elevating the risk of heat-related illness and death, as illustrated by this article that focuses on the final days of Stephan Goodwin's life in 2022. (Some users may encounter a paywall.)

It is recommended that humans consume 2.0 to 3.7 liters (about 4.2 to 7.8 pint glasses) of water daily to replace water lost through breathing, sweating, urination, and bowel movements.

There are multiple HRT options to treat menopause and perimenopause symptoms including hot flashes, vaginal dryness, and mood swings.

Over 200 known species hibernate, allowing them to lie dormant and survive harsh periods when water and food become scarce, such as frigid winter months or scorching summer periods.

City structures cause localized heat zones hotter than nearby rural areas

Urban materials like asphalt and concrete trap heat, while cities lack cooling features like trees and water. Due to hot runoff, urban streams can heat up by as much as 18°F more than forested streams.

Heat is the leading cause of death in natural disasters

Floods are a distant second, followed by hurricanes. That's according to data reported by the National Oceanic and Atmospheric Administration.

Women typically have more robust immune responses than men

This difference helps women better combat infectious diseases, but this more turbo-charged response may also make women more vulnerable to autoimmune diseases by potentially priming their immune systems to overreact to their own cells and tissues and label them as invaders that must be destroyed. Roughly 80% of American women have autoimmune conditions.

Medical recognition of strokes stretches back to ancient Greece

Every minute, 750 milliliters of blood flows to the brain, supplying 20% of the body’s oxygen. A sudden disruption—whether from a clot (ischemic stroke) or a bleed (hemorrhagic stroke)—can be life-threatening. From ancient Greek theories to modern CT and MRI scans, here’s how stroke science has evolved over time.

Humans have used geothermal resources for thousands of years

In North America, Indigenous peoples viewed hot springs as sacred places and used them for medicinal purposes, cooking, and surviving cold weather. The ancient Greeks and Romans also viewed them as sacred, partaking in hot mineral baths to relieve ailments and using them for space heating.

Civilians on short-term spaceflights can experience long-term astronaut health impacts

A collection of 44 studies—primarily based on data from a 2021 tourist trip to low Earth orbit—identified immune system disruption and some kidney damage in tourists, with women appearing to recover from space travel faster than men. Return trips from Mars may require human travelers to be on dialysis.

Brain death is a medical diagnosis without any wiggle room

Seeking to resolve long-standing variations between hospitals and state procedures, in 2023 several expert groups published comprehensive step-by-step guidance for clinicians to follow when determining brain death in kids and adults. Among other guidelines, it stated that doctors don't need to get family consent to do the tests needed to make this determination.

Data centers can be kept cool by circulating fluid over plates atop high-temperature components or by submerging equipment in non-corrosive oil that does not conduct electricity.

More extreme heat days are putting human health at risk in both the short and long term

America is generally experiencing more frequent extreme heat days, over a longer period, in certain parts of the country. The heat-related death toll is rising, and beyond those direct deaths, extreme heat can also have troubling ripple effects including elevated violence and decreased productivity.