Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure.

Chronic exposure to traffic noise is associated with a higher risk of Parkinson's disease.

Listen to a reporter discuss his story spotlighting a decadeslong corporate cover-up about forever chemicals, substances, which can persist in the environment for hundreds of years—though not forever.

How a single company hooked the world on herbicides

How harmful are today’s herbicides for us humans, and for the environments they’re seeping into? And do we really need weedkillers to feed the world?

Rodent evidence is mounting that dysfunctional mitochondria may be a cause of Parkinson's

Though researchers have long observed mitochondrial malfunction in Parkinson's patients, it has remained unclear whether faulty mitochondria cause the disease or are casualties of it. Rodent research published in 2025 adds further weight to the idea that it's causative.

Supplement sales soared during the pandemic, alongside growing distrust of the health establishment, amplifying a trend that endures—even when some of the products don't even work.

Explore the history of antibiotics with 'This Podcast Will Kill You'

The show blends medical history with storytelling and science. In Episode 50, the hosts trace the dramatic origins of antibiotics—from Fleming's moldy petri dish to Florey's wartime labs—and explore their lasting impact on health.

Using psychedelics to manage a cancer diagnosis

Dr. Roland Griffiths helped lead the revival of psychedelic research, often prescribing the use of psilocybin to address severe depression or anxiety in patients. This podcast explores how Griffiths leaned on his own career after being diagnosed with cancer and facing the prospect of death.

Watch 'Last Week Tonight' explore the risks of 'forever chemicals,' a group of human-made chemicals used in everyday products to make them resistant to water, stains, grease, and heat. (Warning: language.)

Park rangers discuss what it's like where two deserts meet

In this 29-minute podcast, two park rangers at Joshua Tree National Park sit down with Dr. Cameron Barrows from the University of California-Riverside to understand what exactly it means for two deserts to meet. Slightly bigger than the state of...

The lack of diversity in clinical trials is undermining the future of precision medicine

Medicine works better when the treatments are tailored to fit each individual person’s biology and history. Homogeneous patient selection in clinical trials means treatments and care are being refined based on only a small range of variables, some of which may not apply to you. This 40-minute podcast episode discusses the historical and current reasons for the lack of clinical trial diversity and what this means for the future of personalized medicine.

Genetic tests aren't always actionable, which is one reason genetic counselors are so vital

This podcast interview with a Harvard Medical School professor focused on cancer genetics and prevention discusses the specifics of genetic testing and insights and the challenges of processing the outcomes of the testing and what may be actionable—or not.

Revelations that apples were sprayed with the chemical Alar led to its ban in the 1980s

Almost three decades after Rachel Carson’s “Silent Spring,” a “60 Minutes” segment on the use of Alar, a chemical sprayed on apples, drew national attention and inspired supermarkets and schools to remove apples from their shelves and cafeterias. That same year, the Environmental Protection Agency took action against the use of the chemical in food.

The gray area that makes PEDs seem like leveling up to hardcore athletes

Doping in sports is broadly condemned as unsafe and unfair. Significant controversies in major sports, including baseball and cycling, have been prompted by the widespread use of performance-enhancing drugs, which are described as clear-cut dangers and abuses of the rules. But to many competitors, the line between a PED and the next smart technique to adopt is unclear. This podcast episode explores that gray reality.

Go inside the global effort that led to the Montreal Protocol in this narrative podcast

Nobel laureate Mario Molina and other key voices recount how science and diplomacy converged to develop a plan to close the ozone hole, offering insight into history's most successful environmental treaty.

Scientists from the frontline discuss the future of antibiotics and superbugs

Superbugs are a very real problem, but researchers around the world are working to advance our understanding of these pathogens and develop new medicines. This podcast talks with several scientists on the frontier of superbug research, offering insight into what we know—and what the future of medicine may look like.

Most of the 86,000 consumer chemicals registered with the US EPA have never received rigorous toxicity testing, though not all those are still in current use.

Hear from a NYC public health official who led the first US investigation into West Nile about the challenges investigators faced and their working theories about that outbreak.

Rachel Carson's 'Silent Spring' exposed the harmful effects of pesticides on food

The 1962 book warned against the use of DDT, a pesticide often sprayed over fields of crops, cautioning that it could be harmful if ingested in excessive amounts by humans. Some credit Carson’s book with inspiring the modern environmental movement and with encouraging the US to establish the Environmental Protection Agency in 1970 and ban the domestic sale of DDT in 1972. (Some readers may experience a paywall.)

Listen to why extensive ear rinsing can create problems

The clinician who hosts this podcast discusses how his patient developed swimmer's ear after he flooded his ears with water during his daily showers, ostensibly to clean them. The resulting itchy, painful ears were the result of removing protective earwax in the ear and also altering the typical pH of the ear.

How a government chemist founded the FDA—by poisoning people

The Poison Squad tells the story of government chemist Dr. Harvey Wiley who, determined to banish these dangerous substances from dinner tables, took on the powerful food manufacturers and their allies.

Dietary supplements are regulated like foods

This hour-long 2016 documentary from Frontline, the Canadian Broadcasting Corporation, and The New York Times examined the safety of dietary supplements. It noted that this then-$30B industry (it's at least doubled since then) suffers from irregularities and impurities. It warned that many Americans are unaware of the lack of regulatory oversight over these products.

Peanut allergies dropped by 43% after doctors reversed avoidance guidance, but questions remain

The study’s data appear to confirm the policy shift. Still, since the study did not include an examination of infant diet, researchers can’t definitively say that the guideline shift led to dietary changes and thus directly caused the decline.

Why processed foods can be so addictive

In recent years, many critics have voiced their concerns about the food industry and how ultra-processed foods affect our health. Despite our awareness of these issues, processed foods are still incredibly hard to remove from our diet. In this podcast by The Guardian, Dr. Chris van Tulleken explains how “junk food” is created to get us hooked, how it negatively affects us, and what we can do to improve our eating habits.

What the research says about the link between lead pollution and crime

The lead-crime hypothesis links childhood lead exposure to impulsivity and aggression as an adult, traits typically associated with higher crime risk. A 2022 meta-analysis found that reducing lead may explain up to 28% of the US homicide decline, but not the broader crime drop.

Rachel Carson didn't argue for wholly organic farming

Her 1962 book, “Silent Spring,” inspired many people to consider the chemicals used to grow their food, but Carson didn’t think that manufactured fertilizers needed to be banned from farming, writing that “The ultimate answer is to use less toxic chemicals so that the public hazard from their misuse is greatly reduced.” When she testified to Congress in 1963, she said, “I think chemicals do have a place.”

A podcast uncovering drug killings in the Philippines

This podcast investigates how many people have been killed in the Philippines since its War on Drugs began. In 2016, Rodrigo Duterte became the President of the Philippines, framing drugs as an existential threat and the root of all crime, saying...

How to avoid a 'bad trip' advice includes relaxing your mind if you experience scary things and not fighting the feeling

In this video, Michael Pollan, author of "This Is Your Mind On Plants," underscores the gaps in existing understanding about the substances and recommends only taking guided experiences, for safety and help. He tackles how psychedelics work, explains microdosing and psychedelic risks, how the substances could be used to treat addiction, and the history of psychedelic stigma.

'Why'd I take speed for twenty years?': an exploration of stimulant ADHD medication

Many people with ADHD are prescribed stimulant medication to assist with symptoms ranging from time blindness to executive dysfunction. This hour-long podcast episode by Search Engine explores the host's experience with ADHD medication and the history of amphetamine and methylphenidate use in the US.

Can we speed up our metabolisms?

Listen to this 31-minute podcast to better understand what science knows and doesn't know about metabolism, as well as the only thing that seems capable of changing it. Scientists understand that the difference between a so-called “fast” and “slow” metabolism does not affect one’s ability to lose weight.

Listen to a podcast that traces the history of DOJ antitrust enforcement

This podcast series traces how the US government's approach to regulating big business has changed over a century—from the DOJ's breakup of John D. Rockefeller's Standard Oil monopoly, through lawyer Robert Bork's influence on how courts interpret competition law, to the FTC's modern antitrust lawsuit against Amazon.

Hear firsthand how scientists and policymakers saved the ozone layer

In this episode, atmospheric chemist Susan Solomon and Protocol architect Stephen Andersen recount how scientific discovery, diplomacy, and public pressure drove the Montreal Protocol—and share lessons for tackling climate change.

Discover how strength training may help your brain and what happens inside your cells when you work out with this original '1440 Explores' podcast.

This 'Science Vs' episode checks the taste, health, and environmental claims about organic food against the actual research.

There are two FDA-approved blood tests that may detect early Alzheimer's disease.

Listen to an amputee describe what it was like in the aftermath of his partial foot amputation and how his chronic, extreme pain fueled his depression and his decision to attempt to alleviate the pain with the radical surgery.

Listen to how gaps in schizophrenia care helped to lead to a murder

Michael Laudor attended Yale, succumbed to schizophrenia, and killed his pregnant fiancée. The podcast, which includes a long but moving interview with Laudor's friend Jonathan Rosen, uses the tragedy to frame how America's approach to severe mental illness has fallen short.

Is Agent Orange still causing birth defects?

Though the dangerous nature of the chemical is clear, its impact across generations is less so. How far down the bloodline does Agent Orange travel, and what does it leave in its wake, if anything? This Scientific American article examines why there’s debate about Agent Orange’s legacy.

Recent evidence raises the question of whether conventional wisdom about amyloid plaques and their connection to Alzheimer's is wrong.

People with tinnitus should avoid silence—sound-rich environments distract the brain

This podcast from an audiologist discusses common questions about tinnitus. It notes that tinnitus could be described as a phantom sound associated with hyperactivity in the brain. It's linked with loud sound exposures above 85 decibels, hearing loss associated with aging and stress, among other factors.

A super-sniffer smelled her husband's Parkinson's disease years ahead of symptoms.

Explore the current landscape for patient consent with this 1440 Original video tied to Henrietta Lacks' legacy.

Two festival-goers were hospitalized after receiving trendy peptide injections, raising safety questions that may extend beyond the event.

The lack of guidance on getting off GLP-1s leaves patients at risk

Dr. David Kessler, former FDA Commissioner and public health leader, explores how these drugs override the brain’s reward-driven eating habits but have notable side effects. These include developing eating disorders, muscle loss, and intestinal obstruction.

How we frame stress—as good or bad—seems to alter how it affects us

This podcast discusses research that indicates stress perception may drastically affect how we respond to it. In research exploring if our stress is presented as diminishing our health versus if we're told it enhances our performance, it will lead to differences in how successful participants are at performing tasks—with the enhancers doing better.

Why bacterial bioremediation may help counter the negative effects of past chemical solutions

Molecules such as DDT, a synthetic insecticide, and PFAS—"forever" chemicals used to make products resistant to heat, water, and grease—have historically been used across various industries but are now known to be harmful. Microbes that can convert some of these substances into nontoxic products, such as water and carbon dioxide, have already been identified, with ongoing research to find others.

An account of unethical behavior by psychedelic guides

Ethical guidelines and protections have a gossamer grasp in the underground psychedelics movement. This 34-minute podcast episode delves into patterns of deception and abuse by movement leaders through one source's deeply personal tale. This episode, which involves descriptions of sexual violence, is one of many in New York Magazine's Power Trip series, a nine-part investigation into the darker side of the psychedelic renaissance.

Ultraprocessed foods are linked with a 58% elevated risk of developing dementia.

See how DOJ prosecutors took down a pharmaceutical company's executives over the opioid crisis

This FRONTLINE documentary follows federal prosecutors as they used anti-racketeering laws to convict executives at Insys Therapeutics, a pharmaceutical company that bribed doctors to overprescribe a fentanyl painkiller.

Used since the 1940s, 'forever chemicals' include thousands of different types of substances routinely integrated into industry and consumer products, yet research suggests they can accumulate in the body over time.

Explore a database of generic drugs to trace their origins and identify any safety concerns.