How neurons give rise to thoughts

Neurons send signals through electrical impulses and chemical messengers

By converting electrical signals into chemical messages at synapses, neurons allow information to travel throughout the nervous system. With repeated use, synapses grow stronger, enhancing the associations between neurons.

Take a deep dive into the neuron

Neurons are the basic unit of the brain and nervous system—electrically excitable cells that sends signals throughout the body. They can communicate with each other, fire in sequence, and conspire to do everything from drive body movement to help form memories. Check out this intro-level overview to learn more about their structure and how they work.

How brain cells carry information

At any moment, there is an electrical storm coursing through your body. Discover how chemical reactions create an electric current that drives our responses to everything from hot pans to a mother’s caress.

Neural rhythms shape how we move, focus, remember, and interact with the world

Millions of neurons in the brain produce rhythmic electrical signals, or brain waves, that guide physical movement and help form and store memories. Researchers also use these rhythms to create brain-computer interfaces, letting people control devices using only their thoughts.

Explore an interactive 3D model of the brain

The brain contains about 86 billion neurons—nervous system cells—and controls vital bodily functions via electrochemical signals. Neurons form circuits through axons, and different brain regions use these circuits to perform specific tasks.

Can physics explain where consciousness comes from?

Consciousness is a complex emergent phenomenon of the brain, which is primarily composed of neurons and glial cells. Since all matter is composed of atoms that follow the laws of physics, there may be quantum processes beyond classical electrochemical interactions that can explain where consciousness comes from.

Explore how excitatory cells, such as neurons and muscle cells, transmit information in the body via electrochemical signals, which can travel up to 120 meters (390 feet) per second.

Age, stress, and neurological disorders can prevent memory formation and recall

Neurons transmit signals between one another at sites called synapses. Repeated interactions at these sites improve the efficiency of signal transmissions, making memories involving sensory data associated with those neurons easier to recall. Biochemical factors impacting these synaptic interactions affect memory quality.

Synaptic plasticity allows neurons to communicate effectively and form memories

First proposed in 1949, synaptic plasticity allows the brain to adjust communication strength between neurons. This ability to change synaptic strength—either briefly or over long periods—is essential for learning and memory, with long-term synaptic plasticity forming the basis of how memories are stored.

Psychedelics set off a flurry of brain activity that may permanently alter it

The brain seems to experience a sharp increase in communication between areas that generally don't interact. New research suggests a thin, sheet-like gray matter structure tucked deep within the brain, between the insular cortex and striatum, may be the key to this change. The area is centrally located and home to many of the receptors that psychedelics target, potentially rewiring the brain and rewriting thought patterns.

How to think yourself into health

Can the right thoughts lead to a stronger immune system? Neuroimmunologists like Hai Qi study how drugs targeting the brain, as well as thought exercises, can prompt stronger immune responses to infection. This six-minute video investigates the radical claims.

Neural implants blur the line between personal intention and machine execution

A key ethical dilemma—the contemplation conundrum—explores whether implants might misinterpret mere imagination as intent to act. Neuroscientists have found no brain signal that clearly marks when someone decides to act, making intent hard to detect in neurotechnological systems.

Why do dreamers twitch?

This thought-provoking piece highlights newer research suggesting sleep twitches may not be random dream leftovers, but instead a crucial way our brains map and understand our bodies. From sleeping rat pups to dreaming octopi, this biological mapping system appears universal across animal species.

What is the brain up to when the mind wanders?

As you stare into the distance while washing your home's seemingly never-ending pile of dishes, the brain activates its default mode network. This collection of "task-negative" brain regions associated with memory, reward, action consideration, and prediction alight with activity when humans mentally turn inward, possibly giving rise to the brain's ability to wander and humans' ability to construct internal narratives about the world.

The dreaming brain, as understood by scientists

Technology has advanced to where the seemingly separate fields of psychology and neuroscience are asking the same questions about dreams, such as whether they're more closely related to perception or visualization. Some field-intersecting findings include research that shows people with impaired face perception don't dream of faces, those with brain legion-related cognition difficulties deal with similar issues in dreams, and children's dreams change in parallel to their cognitive development.

Memories are formed through attention, repetition, and emotional significance

Our brains create memories by taking in sensory input, filtering it through short-term memory, and storing it in long-term memory. Emotional events are more likely to become vivid, lasting memories because they activate stronger neural connections.

Brain-computer interfaces create a direct link between the brain and external devices

The technology enables users to control prosthetics, computers, or even games using only their thoughts. In 2021, a monkey played table tennis using only its brain, thanks to a Neuralink device, marking a major milestone before human trials began in 2024.

Some animals may speak because of duplicated connections in the brain

Neuroscience suggests that connections responsible for motion made during embryonic brain development—such as those connecting hearing and movement pathways that allow reactive motion when started—are duplicated and connected to the larynx in some animals. This allows some mammals and song-learning birds to speak, provided they have the necessary physiological structures.

The world's first commercial biological computer combines neurons with silicon

Australian start-up Cortical Labs unveiled CL1, a hybrid chip designed to help scientists study brain function in real-time. The 800,000 lab-grown neurons on the chip are kept viable for six months via a built-in life support system.

The body's master clock has 20,000 neurons

The suprachiasmatic nucleus, the master clock in mammals, has 20,000 neurons that help maintain the light-dark cycle in the body. Among its jobs: It receives light input information from the retina and then signals peripheral body clocks to act on this information, driving everything from body temperature to hunger.

What's with the teen brain, anyway

In this video NIDA explores the intriguing similarities between the processes of brain development and computer programming. This analogy helps us understand why toxic environmental factors like drugs, bullying, or lack of sleep strongly affect a teenager's life The information provided by this video can empower your children or students with information they need make better decisions.

Elon Musk's Neuralink's N1 chip can wirelessly read brain signals from over 2,000 electrodes

The device is a battery-powered brain implant that transmits data via Bluetooth. Neuralink's near-term objectives for the device focus on unlocking new treatments for paralysis, neurological disorders, and some psychiatric conditions.

Your brain appears to age in five distinct stages, with the pattern of connections inside your brain shifting, on average, around ages 9, 32, 66, and 83.

The brains of people who experience frisson have unique neural pathways

A small 2016 study aimed to investigate the behavioral and neural differences between 10 individuals who experience goose bumps when listening to music and 10 who typically don’t. Scientists reported that individuals experiencing musical chills had greater white matter connectivity in specific auditory, emotional, and social processing areas of the brain.

The limbic system drives emotion, memory, and survival instincts in the brain.

This interconnected group of brain structures—including the amygdala, hippocampus, thalamus, and hypothalamus—processes emotional responses, regulates bodily functions, and plays a key role in memory and learning.

Neural networks mimic the structure and behavior of real physical systems

Early generative AI systems were inspired by scientific models such as the Ising model, which explains how atoms interact with one another and align in magnets. As these networks have expanded, their behavior has more closely resembled that of quantum fields, enabling them to be used in exploring complex particle physics interactions.

Dream interpretation has evolved from ancient mystical explanations, to dream reports, to tracking electrical activity in the brain and more.

How aging degrades neural functioning in the brain over time

Aging affects the brain perhaps more than any other organ in the body. Throughout life, the brain experiences radical shifts in the number of neurons, synaptic connections between neurons, and hormone levels that regulate our mood and processing.

Brain activity sometimes goes into overdrive around the point of death according to researchers' recent analysis of patients' brains before and after they were taken off their ventilators.

Our sense of smell affects what foods taste like and how we perceive it

Scent stimulates our olfactory sensor neurons high in the nasal cavity, and the brain attaches labels to those scents. But when we eat, chemicals from the foods travel from our mouths and throat to those neurons. We have roughly 400 odor receptors, and they can be used to decipher more than 10,000 different odors (or more than one trillion by some calculations), including the nuances of different foods.

Retrieval cues trigger memories and emotions from long-term storage

Retrieval cues can activate specific cells in a neural network, creating a cascade of neurons that collectively make up a memory. Specific cues help regulate emotions during stress by activating positive memories.

Scientists have unraveled new details about which nerve cells control goose bumps

Research in 2016 revealed that at least eight different types of neurons are associated with the sympathetic nervous system. One finding revealed that goose bumps and nipple erection are caused by neurons specialized to regulate these specific functions by controlling the erectile muscles in those tissues.

During dream sleep, the brain connects new information learned during the day with information already stored in the mind, creating a revised mind-wide web of associations.

Exercise releases chemicals that enhance cognitive function

Neurotransmitters like dopamine, serotonin, and norepinephrine, along with increased brain-derived neurotrophic factor levels, enhance a wide range of brain functions. New research demonstrates a direct link between movement and numerous cognitive benefits, including memory, learning, and stress resilience.

Listen to how the gut microbiome influences your emotions

The gut-microbiome connection may involve the enteric nervous system, a collection of hundreds of millions of neurons throughout the gut that transmit signals up the vagus nerve to the brain.

Using brain implants to restore vision

Several companies are attempting to create brain-computer interfaces that skip over retinas and optic nerves to allow visual input to go straight to the brain, potentially restoring some sight to the blind. Clinical trial findings suggest restored sight is sparse and manifests differently than a sighted person might expect, appearing as specks of "light" clusters called phosphenes to help differentiate one's surroundings.

How the brain processes a calendar year

When most of us picture a calendar year, we have a foggy image in our minds of the months, in rough, calendar-like grids. But for some folks, that picture is a whole lot more clear. Around 1 percent of the population has a strange ability known as "calendar synaesthesia," which means they're able to visualize in crisp detail an elaborate calendar of the months of the year. Learn how it works here.

Two scientists argue consciousness evolved through 'unlimited associative learning,' the ability to learn almost any new pattern during a lifetime.

There's a new (contested) physiological explanation for near-death experiences based on analysis of the brains of resuscitated coma and cardiac arrest patients.

A web of sensory neurons in the skin help filter out background sensations

The somatosensory system helps us organize and navigate our surroundings, enabling us to understand our bodies in relation to our environment and also filter out minor sensations that are basically background noise so they aren't overwhelming to our bodies. Meanwhile, viscerosensation—or internal sensation—refers to the internal sensory neuron system that conveys information from internal organs to the brain.

The main criticism of a recent neurophysiological explanation for near-death experiences is that these events are too complex to be explained as a neurochemical response to an oxygen-deprived brain.

Grief rewires the human brain

The human brain handles stress and emotional traumas similarly. In response to the emotional stress of a situation like the death of a loved one, divorce, or abuse, the brain may strengthen or weaken connections between nerves to form new neural connections. Over time, chronic stress can diminish brainpower, reducing overall nerve growth and memory to shift resources to enable elevated fear responses and enable humans to survive.

Some scientists argue NDEs are constructed by the brain, not actually experienced

Despite the powerful memories associated with NDEs, scientists question the idea that the experiences prove consciousness endures after death, opting instead to find physiological explanations for common reports of out-of-body experiences, euphoric and lucid thinking, and more.

Scientists are studying dying patients' brain activity in the final moments of life

In the final moments of life there are distinctive bursts of coordinated neural activity. Researchers are interested in parsing that data to better understand the dying process and also exploring how this data relates to our understanding of consciousness.

Schizophrenia is being studied with pea-sized 'mini-brains'

Brain organoid research is enabling researchers to study distinct electrical firing patterns associated with schizophrenia. These "mini-brains" that are constructed in the lab from patients' cells could lead to better diagnosis approaches and drug development.

What exactly is dopamine?

Dopamine is a neurotransmitter—a chemical released by neurons that enables neural communication—that makes people want things with an "almost animalistic desire," compelling them to snack or check phone notifications. Often misrepresented as a "pleasure" chemical, dopamine is involved in motivation, learning, attention, habit formation, and more. Trends like dopamine fasting overinflate its role in mental health and often use it as part of "straw man" biohacking claims.

Itching is caused by stimulated nerve cells in the skin

Scratching produces low-level pain signals to the brain, distracting from the itch. Scratching also releases serotonin, a neurotransmitter that creates a happy sensation, which resets the itch signal. This can cause a cyclical itch-scratch cycle.

'Susan's Brain': what happens to the brain during addiction

This engaging animation from Harvard Online breaks down the neuroscience of addiction through the story of “Susan’s brain,” demonstrating how addictive substances hijack normal reward pathways. Through clear visual metaphors and approachable narration, it explains complex brain chemistry in understandable terms.

Like fingerprints, brain anatomy is unique too

Researchers have discovered that a combination of experiences and genetic factors shape the anatomy of the human brain. They found even quick experiences affect the brain’s genetic makeup, which—over time—means every person develops a completely unique brain anatomy. While brain imaging could be used to identify individuals, it remains much more expensive than fingerprinting for now. Read to found out more about this study from the University of Zurich.

How science explains déjà vu

Take a fun look at the science explaining the odd experience of déjà vu, which some theories suggest is actually a sign of a healthy brain.