Up to 400 milligrams of caffeine a day is considered safe

The American Heart Association says adults can safely drink up to five cups of coffee per day and regular consumption may improve cardiovascular health.

Coffee is, generally, good for your health

While overconsumption certainly has its drawbacks—hello, not sleeping until the sun rises—on the whole, coffee is fine, even beneficial, for your health. It can even help prevent serious health conditions, like heart attacks and liver cancer.

Coffee is addictive, and those going through withdrawal often experience headaches and fatigue.

Coffee contains an average of 15mg of caffeine per fluid ounce

Coffee has three times the amount of caffeine contained in most caffeinated sodas, but significantly less than espresso and cocoa powder.

A caffeine calculator

This simple calculator takes your preferred caffeinated drink and your body weight to determine how much is the right amount, and how much might kill you. In case you've ever had the morbid curiosity about just how much of that tea you'd have to drink to doze off forever. Find out your moderate and lethal doses here, as well as some extra info on caffeine consumption.

Coffee gives you energy, but it ultimately makes you more tired

The caffeine in coffee delays your brain's fatigue signals. Caffeine blocks adenosine, a compound that builds up as you burn energy and signals rest. Once caffeine wears off, adenosine floods back, leaving you even more tired.

Anxiety is one of the world's most common mental health disorders, causing persistent excessive fear and worry that interferes with daily activities.

See how much daily sugar substitute intake the FDA considers to be safe

The agency states in this PDF graphic that a person weighing about 132 pounds would have to consume roughly a couple dozen sweetener packets daily—or more—to reach unsafe levels of consumption. The accumulated consumption would be across all sources, including diet beverages, sugar-free candies, and actual packets added to coffee.

Even brief physical activity can trigger the release of neurotransmitters that provide mental health boosts.

Just a 10-minute mental health break can yield benefits

The US CDC offers recommendations for alleviating stress in daily life. Short 10-minute breaks can significantly improve mental health, especially when used for activities like deep breathing, dancing, or writing down things you are grateful for. Building meaningful relationships, termed "social connectedness," can also alleviate stress and promote resilience.

The WHO labeled aspartame as 'possibly carcinogenic' but US regulators consider it safe

The International Agency for Research on Cancer, an arm of the World Health Organization, labeled aspartame—the artificial sweetener in Diet Coke—as one of several hundred possible cancer-causing substances in 2023. The determination was based on animal and human studies and "limited" evidence linking it to liver cancer. The WHO and US Food and Drug Administration both say the substance is safe at moderate levels. The FDA says a person weighing about 132 pounds would need to have 75 packets daily to reach an unsafe level.

Anxiety can arise at any stage of life and make someone feel unsafe in their mind and body.

Some data shows cold showers can help with depression

An icy water exposure can lead to the release of norepinephrine, cortisol, dopamine, and other stress hormones that are beneficial, among other potential effects. Some data shows that this type of exposure can help combat depression symptoms among some patients, but more research is still needed. (Some users may encounter a paywall.)

Certain medications that affect blood flow or mood boost the risk of heatstroke

Drugs that narrow blood vessels, beta blockers that regulate blood pressure, diuretics, antidepressants, and antipsychotics can all affect the body's ability to regulate its internal body temperature, and so individuals taking these medications need to take special care in extreme heat and when exercising in hot conditions.

Kava, kratom, St. John's Wort, and green tea extract present health concerns

Consumer Reports, which tests supplements for safety, urges consumers to avoid these four supplements due to safety warnings from researchers and public health authorities.

Can microdosing improve mental health?

Animal studies involving microdoses of psilocybin, the psychoactive component in magic mushrooms and ketamine, found it helped to alleviate anxiety and inflammation, an immune response that can cause damage when chronically active. Human studies are ongoing. In at least one double-blind study, where researchers and patients don't know who got a placebo versus the real thing, about half of the participants incorrectly guessed they had been given placebos.

The depression paradox refers to a lack of energy to take action to help alleviate it

Activities like exercise, even at low levels, have been shown to alleviate some of depression's symptoms for some people. However, depression saps energy levels, making it particularly difficult to motivate oneself to take helpful action.

1 in 10 US adults are taking medication for depression

A US government report indicates that about 10% of US adults took prescription medication for this disorder in 2023. Women, at 15.3%, were more than twice as likely to take one of these medications than the 7.4% of men.

Some types of stress (eustress) have positive benefits

While many perceive stress as solely negative, stress can in fact be divided into two categories: distress (negative stress) and eustress (positive stress). Moderate levels of stress are positive in that they can boost motivation and promote resilience, which have positive mental health benefits.

The side effects of falling back and springing forward

Daylight saving time can interfere with a person’s sleep schedule, but it also has been linked to increased rates of depression, heart attack, stroke, cancer, and car accidents. UT Southwestern’s Dr. Joseph Takahashi explains why the time change is bad for your brain and health.

Eating too much salt can worsen vertigo

High salt intake can cause fluid retention in the inner ear, worsening vertigo. Slashing sodium amounts (and caffeine and alcohol consumption) are particularly recommended for those suffering from Ménière's disease to help stabilize inner ear fluid levels.

The myth of sugar rushes vs. the reality of sugar crashes

It's generally accepted that sugar rushes are a myth, and that hyperactivity is a more psychological experience. However, there is real science behind the rare sugar crash that primarily impacts those with diabetes. Read this article to understand how historical and cultural factors have shaped sugar perceptions, and how low blood sugar can trigger shakiness, fatigue, weakness, and more in diabetes patients.

Yoga is believed to improve mental health, but studies are not definitive

Many think that yoga's combination of stretching, focused breathing, and contemplation help treat depression and anxiety, but the data has often relied on small, homogenous sample sizes.

Stress and the brain

While an acute stress response is a normal bodily function, the effects of chronic stress can be extremely damaging to the human body. This is particularly true with regard to the brain. This article explores the effects of stress on the human brain, including how chronic stress may lead to psychological conditions such as depression and memory loss.

Stress activates the "fight-or-flight" response when we face threats, a reaction that can help keep us alive.

The 10 top tips a psychotherapist offers her patients with anxiety include "you will not die from anxiety" and "anxiety is just trying to protect you."

Antidepressants alone may fail to help an estimated one-third to one-half of depressed patients.

Fantasy sports can have adverse health effects

Experts warn that fantasy sports, including fantasy football, can encourage obsessive use because they offer hits of dopamine. Daily fantasy games, which function more like gambling, are especially problematic.

Exercise releases chemicals that enhance cognitive function

Neurotransmitters like dopamine, serotonin, and norepinephrine, along with increased brain-derived neurotrophic factor levels, enhance a wide range of brain functions. New research demonstrates a direct link between movement and numerous cognitive benefits, including memory, learning, and stress resilience.

Can you overdose on vitamins?

Many people pop a multivitamin supplement each day thinking that any excess nutrients won't hurt them. This article explains how chronic excess of any vitamin can cause toxic levels in the body. This condition is known as hypervitaminosis, and symptoms vary depending on what vitamins have achieved toxic levels of accumulation. According to this article, dietary supplements in the US are not required to submit to the FDA documentation supporting their efficacy or safety.

Supplements often have issues with impurities, toxins, and inaccurate labels

Consumer Reports' tests of more than 20 supplement powders and shakes in 2025 found that more than two-thirds of them contain unsafe levels of lead. Some contained 10 times the amount of lead that's considered acceptable to ingest in a day. The levels they found, in some cases, were even higher than when they tested the products 15 years earlier.

US depression rates at historic high among adults

More than 18% of US adults reported that they currently have or are being treated for depression in both 2024 and 2025. In the 2025 survey, more than 11,000 adults were surveyed. The numbers have ticked upward since 2015—by about 8 percentage points—with most of the increase occurring from the 2020 pandemic onward.

Exercise improves brain blood flow, stimulates neural growth, and more.

Menopause can exacerbate anxiety

Some research shows that menopause can fuel anxiety and also that preexisting anxiety can boost the chances of experiencing other menopause symptoms, including hot flashes, insomnia, and brain fog. But treatments—including hormone replacement therapy, breathing exercises, and other forms of exercise—can alleviate some of these symptoms.

Psychedelic side effects, including worsening mental health for some patients, give pause

This article explores whether the therapeutic potential of psychedelic drug use is really as good as current research suggests. Scientists are exploring its applications for conditions ranging from the existential crisis that can accompany terminal diagnoses to chronic mental health conditions, including anxiety and PTSD.

Depression is much more than sadness—and isn't fleeting

The American Psychiatric Association's DSM-5—used for defining diagnoses—says a person must be experiencing five or more symptoms of depression most of the day over at least two weeks. Research indicates older people are less likely than younger people to meet that depression benchmark, though this article says they still often have at least several of the depression symptoms.

Consuming true crime media can increase stress and anxiety and create a false sense of danger.

Most adults don't need a daily vitamin, and it won't extend your life

A 20-year study by the National Cancer Institute involving almost 400,000 people found that daily multivitamins did not help people live longer. In some cases, these vitamins also increased the risk of death. Although some subpopulations—such as those with documented vitamin deficiencies and pregnant individuals—should take vitamins, daily multivitamins should not be taken uniformly by adults. Instead, patients should discuss vitamins with their clinicians and consider baseline vitamin testing before starting vitamin regimens.

Overmedication has put type 2 diabetics at risk of low blood sugar

Type 2 diabetics in the US risk dying from low blood sugar, an epidemic traced to a decades-old, multi-million-dollar drug industry campaign encouraging an average blood sugar level below 7%. Contemporary research correlated such levels with reduced risk of eye, nerve, and kidney damage and increased hypoglycemia risk.

How depression affects the brain

Treatment for depression has historically hinged on the theory that the condition was caused by underactive or abnormal neurotransmitters, specifically serotonin and norepinephrine. This four-minute video by Yale Medicine details how these neurotransmitters didn't explain the symptoms of depression but, two other neurotransmitters involved in regulating mood and emotion did. GABA and glutamate, some of the brain's most plentiful neurotransmitters, may possibly be the source of depressive symptoms.

Health officials recommend at least 150 minutes of aerobic exercise per week and 2 sessions of resistance training, targeting each major muscle group.

Bees are more likely to remember a flower if its nectar contains caffeine

Plants want pollinators to keep coming back, so the finding suggests that some plants, such as Citrus and Coffea species, have evolved to include caffeine in their nectar. Researchers suggest the findings could help develop methods to reinvigorate pollinator populations.

Bupropion is the only antidepressant approved for the preventive treatment of SAD

Clinical trials showed a 44% reduction in risk for recurrence of SAD for those who took the drug compared to a placebo group. Bupropion is a norepinephrine–dopamine reuptake inhibitor, which increases dopamine (other common antidepressants, known as selective serotonin reuptake inhibitors, sometimes can suppress dopamine, but not always).

Ultraprocessed foods are linked with a 58% elevated risk of developing dementia.

Mental health applications of psychedelics

Scientists are investigating psilocybin, ketamine, LSD, and MDMA (also known as ecstasy) as potential treatments for mental health issues. These drugs enable an altered state of consciousness, which can have beneficial or harmful impacts depending on the nature of the experience. Research suggests these drugs can be effective in treating substance use disorders, mental health conditions, including depression and anxiety, and psychiatric disorders, including schizophrenia.

Chocolate can be deadly in humans, but only after consuming extraordinary quantities

Based on tests with mice, the lethal dose of chocolate is estimated to be no more than 1,000 mg/kg. This means that the lethal dose of dark chocolate for the average US adult is about 6.5 kilograms (14.33 pounds), or about 8,300 Hershey's kisses, in one sitting.

Are cats good for our health?

Being a cat lover can have a profound effect on your life. This article in The Conversation presents a fascinating collection of findings related to the benefits and consequences of cat ownership. Discover compelling research about the positive heart health and mental health outcomes cats can bring, along with potential risks.

Too little stress can also harm our health because mild or moderate stress—followed by recovery—helps make us resilient.

Supplements are only typically recommended for those with a proven deficiency

Blood tests and other dietary screening tools by clinicians and nutritionists can indicate whether someone is deficient in needed vitamins or minerals, and those results can then lead to a personalized care plan that may include supplements. Supplements can negatively interact with certain medications, so it's important to speak with your doctor about supplements before taking them.

Some claim breathwork can improve mental health, help process trauma, and more

Research shows people who practice breathing exercises see a decrease in depression and stress levels, and that such exercises are about as effective at treating PTSD as conventional approaches. Even something as simple as extending exhales can slow one's heart rate and activate the parasympathetic nervous system.