One biologist is leading the blue zone criticisms—both questioning the original recordkeeping for these purported longevity-prone locations and pointing to recent research showing declining numbers of healthy seniors in several official blue zone regions.

Blue zones are geographic locations, such as Sardinia, Italy, where there have appeared to be disproportionately high numbers of healthy agers, perhaps due to factors including genetics, diet, social connections, and more.

Blue zones are regions with unusually high numbers of centenarians

Factors thought to contribute to longevity in these regions include diet and social connections, but their legitimacy is often questioned due to a lack of rigorous scientific methodology and potential record inaccuracies.

Read the main paper criticizing the concept of blue zones, which argues recordkeeping errors, pension fraud, and natural disasters likely explain the high numbers of purported healthy centenarians in certain locations.

Most self-reported claims of exceptional longevity are exaggerated, but read how demographers verify age claims and why some of the original blue zone demographers say blue zone regions are real and worth studying.

Visit these 'blue zones,' where people live the longest

Blue zones, a term coined in 2004 by National Geographic Fellow Dan Buettner, are regions in the world where people live the longest and healthiest lives. Researchers have identified a few key aspects defining the culture of these areas—physical activity, diet, purpose-driven lives, and more. Explore the top five blue zones from across the world here.

Dan Buettner, the journalist who popularized the term blue zones, fires back at criticisms of blue zones in this 2026 letter to the editor published by STAT News.

Watch the trailer for journalist Dan Buettner's popular Netflix documentary series 'Live to 100: Secrets of the Blue Zones,' which focuses on longevity insights from populations around the world.

In the original 2004 blue zones study, which sought to verify the ages of long-lived, healthy populations in Sardinia, Italy, researchers hypothesized that inbreeding in these isolated communities may have helped promote their longevity.

Blue zone cooking—a concept that journalist Dan Buettner developed from his reporting on centenarian populations—emphasizes cooking with simple, fresh ingredients and echoes themes of the well-known Mediterranean diet.

Fort Worth, Texas, is the largest US blue zone area—a designation not from demographers but from journalist Dan Buettner's organization, which means Blue Zones LLC partnered with the city to help residents live healthier.

The formula behind super agers—those possessing health and cognitive skills of people decades younger

A study of about 1,400 super agers did not identify any underlying genetic mechanism for longevity. While researchers instead emphasized that sustainable habits involving positive social connections, sleep, mood, diet, exercise, and personal fulfillment help reduce long-term risks, there is no one-size-fits-all formula for everyone.

Super-agers: seniors 80 and above with the memory ability of people in their 50s

Studies show the number one indicator of whether someone is a "super-ager" is not diet or genetics, but the extent of their social relationships. Moreover, scans reveal noticeable physical differences in certain parts of the brain in patients with extensive social networks.

Can humans delay or reverse old age?

We're not sure yet. Researchers at the University of California San Francisco are studying why some conditions and behaviors, such as low-oxygen environments and exercise, benefit the aging process, hoping to reveal potential health applications. Some of this research focuses on klotho, a naturally occurring age-regulating hormone named after the Greek Fate Clotho. Animal studies on klotho brain injections found subjects had improved memory recall and age-related degeneration resistance.

Multiple new research paths may lead to slowing (or even reversing) aging

Aging has always been inevitable, but fasting, epigenetic reprogramming, and parabiosis seem to help people stay young. By studying centenarians, memory, and even the humble roundworm, scientists are looking for the genetic basis to live not just a long life, but a healthy one.

The quest to find natural ways to extend lifespan

Tales of searching for the Fountain of Youth persist. Our modern-day version is marked by promises of pharmaceutical miracles and a proliferation of viral "biohacking" routines. One doctor’s quest to unlock the keys to longevity stimulated much of this renewed fervor, though his ideas are often taken out of context.

Perceived isolation ages you

Mounting evidence suggests that socialization is a vital component of maintaining good health. Research published in 2024 from Mayo Clinic researchers analyzed the social lives of more than 280,000 adults and concluded that individuals that weren't likely to participate in extracurricular social activities and get-togethers were more likely to have a biological age older than their actual age—meaning that you may be 60 but health indicators would suggest you're older.

Moving your body every day is key to longevity

In an era of biohacking, where millionaires subject themselves to draconian routines and tests to de-age themselves, one study suggests a super simple key predictor of mortality: more than any other trait, how much subjects moved determined how long they'd live. Movement mattered even more than age in predicting overall life longevity. Researchers suggest this means we should all simply get outside a bit more. Read more about the study here.

The Dog Aging Project uses information from over 50,000 dogs to explore longevity

The study gathers health, lifestyle, and genetic data to understand what helps dogs live longer, healthier lives. Findings could also provide human health insights due to our shared surroundings and biology.

Doctors shift focus from extending lifespan to lengthening health span

As scientific advances extend the average human lifespan, many are turning their attention toward extending "health span." Health span refers to the number of years one is active and disease-free. The ultimate goal is to extend one’s health span to match one’s lifespan.

Health span: The number of years one is active and disease-free

As scientific advances continue to extend the average human lifespan, many are now turning their attention toward extending "health span." The ultimate goal would be to extend one's health span to match one's lifespan, which would necessitate a shift in focus toward the pursuit of healthy aging. (Some users may experience a paywall.)

Monaco has the world's oldest population, with more than 36% of residents aged 65 or older, according to World Bank data.

Helping support others in older age linked to longer life

Analysis of findings from a long-term study of older couples first interviewed in 1987 and then followed for the next five years found that individuals who lend support to friends, neighbors, and relatives live longer. Non-helpers were more than twice as likely to die as helpers during the five-year period. That's even after controlling for factors including age, gender, and physical and mental health.

Doctors use three key physical markers to determine biological aging

The length of the ends of chromosomes (known as "telomeres"), the gradual change in collections of DNA molecules called "methyl groups", and the secretion of inflammatory proteins are all used as indicators of biological age.

An analysis of ancient texts found that dementia was rare in ancient Greece.

Environment and genetics explain why animals have widely different lifespans

Both environmental conditions and genetic factors shape how long various animals live. For some creatures, colder conditions allow for less energy use and slower aging. Larger animals have fewer predators. While humans don't live the longest, we are a rare species that successfully lengthened its average lifespan over time.

The disparity in life expectancy between wealthy and impoverished nations has notably narrowed

In 1950, people in Norway lived to age 72, on average, while those in Mali lived to just 26. By 2015, the countries with the worst conditions had made such significant progress that the global average life expectancy had surpassed the rate of any nation in 1950.

Inflammaging appears to differ across global populations

Chronic, low-grade inflammation linked to aging is a byproduct of our industrialized lifestyles, according to recent research. The work compared two industrialized populations with two Indigenous, non-industrialized populations in Bolivia and Malaysia, and found that inflammation levels in the Indigenous groups—unlike the industrialized ones—did not seem to differ by age.

Biological aging tests assess the breakdown of physiological systems

Known as aging clocks, these tests compare various metrics, like DNA methylation patterns and protein profiles, to healthy baselines. However, the non-uniformity of these baselines across individuals limits testing accuracy and prevents their clinical use.

Chronological versus biological age

Science has come to understand different types of aging. What we call age is simply the number of years since birth, or chronological age. At the cellular level, biological aging happens at different rates for different people, and explains why some seem to age more quickly (or slowly).

Global life expectancy has more than doubled since the 1850s

The human species experienced a dramatic increase in expected lifespan over the past 150 years. Antibiotics, improved sanitation, and better worldwide food distribution are a few factors contributing to this rapid transformation. Use this interactive resource to explore longevity gains over time and compare these improvements across the globe.

At-home genetic testing results commonly led users to healthier lifestyles

Italian research that aimed to investigate what people do longer-term after receiving direct-to-consumer genetic test results indicated that whether the results were positive or negative, people tended to adopt a healthier diet after receiving the results, and they'd still maintained it a year after receiving their results. Some users also reported an overall reduction in stress over their health concerns. (Some users may encounter a paywall.)

Visualizing cause of death over time in America

As people age, their life expectancy decreases, but the timing and speed of this decline have evolved over the years. Check out this chart which shows the shift in various causes of death of Americans over the last few decades. Data from the...

In 2026, University of Cambridge researchers reported that a group of gut bacteria called CAG-170 may be a key marker of good health, occurring far more often in healthy individuals and less commonly in people with chronic diseases.

Roughly 10% of the world's population is older than 65 (2023 data)

With recent advances in medicine, sanitation, and nutrition, expected lifespans have rapidly risen around the globe—resulting in a rapidly aging global population. The worldwide distribution has seen a nearly 600% jump in the population of people aged 65 and older.

Yoga can be beneficial for aging practitioners

Studies suggest that yoga can help alleviate several diseases associated with aging by lowering blood pressure, reducing blood fat levels, and combating obesity. It has also been shown to increase telomerase activity, which helps slow cell aging.

Why Hawaiians live longer

Hawaii has the longest life expectancy at birth out of all 50 states, according to the US Centers for Disease Control and Prevention. Key factors include strong healthcare, lots of sunlight, and active lifestyles.

Each part of the human body experiences aging differently

With global average life expectancy cresting at 73 years, understanding how the body ages is imperative to effective medical treatment and maintaining a desired quality of life. This 13-minute video dives into how the body and its organs age "from head to toe."

The eight habits that could add up to 24 years to your life

A study presented at the American Society for Nutrition's annual meeting revealed that adopting eight healthy lifestyle habits in middle age can significantly increase life expectancy. The habits include being physically active, avoiding opioid...

A Nobel laureate discuss whether stem cells can extend lifespan

Listen to Nobel laureate Shinya Yamanaka discuss the potential of induced pluripotent stem cells to extend human lifespan. By reprogramming adult cells into embryonic-like stem cells, scientists might be able to rejuvenate tissues and treat age-related diseases—though ethical and safety concerns remain.

Some researchers have pushed for 'food deserts' to be rebranded as 'healthy food priority areas.'

Aging is a complex biological process affecting our cells, tissues, and organs.

Do people really look younger than they used to?

Why do people today look younger than they used to? From style to science, there are 3 surprising reasons we age differently now.

Explore this animated story about loneliness that situates modern statistics about isolation.

Can fasting help you live longer?

Animal studies into the health benefits of calorie restrictions of 20%-40% suggest it extends life spans and reduces incidents of age-related diseases, including cancer. This article explores the research into fasting, calorie restriction, and longevity.

This 'Science Vs' episode checks the taste, health, and environmental claims about organic food against the actual research.

Extending the worldwide lifespan by one healthy year is worth $38T

This econometric study attempts to estimate the economic value of increasing the global healthy lifespan by one year—and to answer the question of whether it is better to extend lifespans or slow the rate of healthy aging.

Read a study documenting how 'old people' smell increases with age

Analysis of body odors from individuals aged 26 to 75 confirmed that 2-nonenal, an unsaturated aldehyde with an unpleasant, greasy, and grassy odor, was detected only in subjects aged 40 and older.

Scientists have not yet answered what the evolutionary benefit may be of menopause

Few animals are known to experience menopause, raising questions about why it would be evolutionarily advantageous to have women survive past their reproductive years. One leading hypothesis is the grandmother hypothesis—older women and other species known to experience menopause, like whales, can aid families and pass down knowledge to future generations.

Americans are retiring later than they used to

A Gallup poll from 2022 found that the percentage of adults between the ages of 55 and 74 who are retired is declining.

Less than 1% of aging studies consider menopause and its effects

Nearly all studies researching the biology of aging don't consider menopause in their setup. In part, that's because menopause is difficult to emulate in animal models. Menopause is uncommon in the animal world beyond humans and whales. This presents a problem for medicine and science because about 75% of aging-related diseases are likely influenced by menopause.