VO2 max measures the body's ability to use oxygen to produce energy

One minute of exercise correlates to five extra minutes of life (on average).

Muscles fatigue due to the loss of energy like ATP and glycogen

Adenosine triphosphate fuels muscle contraction, and with each contraction (like during exercise), the amount of ATP reduces. ATP helps potassium and sodium move across muscle membranes, generating ions and helping to contract the muscle.

Exercise helps make your arteries more elastic.

What is metabolic rate?

Read this article to better understand the concept of metabolic rate, which is defined as the amount of energy expended by an organism over the course of a day. Basic metabolic rate (or BMR) is this metabolic rate at rest, during which the body only...

Optimal human functioning requires movement

There is now ample evidence to back the centuries-old hypothesis that exercise is critical to human health. This review article explores the latest discoveries in exercise science, including how exercise is intrinsic to maintaining our organ systems throughout life.

Explore how to safely start 'strengthmaxxing' with body weight—not actual weights.

Exercise can lead to muscle microtears, but the body's repair systems cause those fibers to grow back larger.

On average, the human body produces about 100 watts of electricity—enough to power a light bulb—but some people can produce over 2,000 watts in short bursts, such as when sprinting.

How endurance athletes can build resilience

Long-distance runners and other endurance athletes can improve their performances using tips explored in this article. Findings from two recent studies show that strength training, high-altitude training, and intense interval sessions are all potential methods for ameliorating long-term athletic capabilities.

Recent global health estimates suggest that inactivity is a leading risk factor for death, contributing to 6% of deaths worldwide.

How does your body turn food into energy?

Cells get energy via a process known as cellular respiration, which involves turning glucose into ATP or adenosine triphosphate. Breaking the phosphate bonds of ATP results in usable energy being released into cells, which can then use that energy to power biological processes. This 10-minute video explains how glucose turns into ATP, giving the body the energy it needs to survive.

Why death is caused by a dearth of ATP

Though people die from many causes, this video makes the case that a lack of adenosine triphosphate production in the body is what kills almost all of us. Without ATP, physiological processes grind to a halt, and organs stop functioning.

Health officials recommend at least 150 minutes of aerobic exercise per week and 2 sessions of resistance training, targeting each major muscle group.

Developing adaptable brain-body systems lets athletes thrive beyond 30

Success in high-level sports after age 30 relies on physical fitness and building brain resilience through deliberate training, recovery, and stress regulation. This creates a feedback loop where body and mind reinforce each other.

Blood pressure readings correspond to the peaks and valleys of heart beats

Pushing 2,000 gallons of blood through the body every day exerts a force known as blood pressure. Blood pressure is highest during the heart's contractile phase, known as systole, which forces blood through the circulatory system, and lowest during the heart's resting phase between beats, known as diastole.

Can humans delay or reverse old age?

We're not sure yet. Researchers at the University of California San Francisco are studying why some conditions and behaviors, such as low-oxygen environments and exercise, benefit the aging process, hoping to reveal potential health applications. Some of this research focuses on klotho, a naturally occurring age-regulating hormone named after the Greek Fate Clotho. Animal studies on klotho brain injections found subjects had improved memory recall and age-related degeneration resistance.

Astronauts exercise on the International Space Station

Astronauts maintain bone, muscle, and cardiovascular health with physical activity. It's crucial that they make time to exercise for approximately two hours per day. This resource offers a behind-the-scenes look at how high-intensity workouts help prevent muscle atrophy, bone density loss, and aerobic decline during monthslong space missions.

Can we speed up our metabolisms?

Listen to this 31-minute podcast to better understand what science knows and doesn't know about metabolism, as well as the only thing that seems capable of changing it. Scientists understand that the difference between a so-called “fast” and “slow” metabolism does not affect one’s ability to lose weight.

Exercise improves brain blood flow, stimulates neural growth, and more.

Official recommendations state that healthy adults should perform progressive resistance training that increases weight and repetitions over time.

See this 201-level explanation about mitochondria and mitochondrial replacement therapy

This 2022 academic presentation from Stanford University's Dr. Gregory Enns offers a detailed overview about mitochondrial therapy approaches. Enns, a pediatric geneticist, explains how well-functioning mitochondria support the human body.

Myokines are molecules that facilitate some of the benefits of exercise

When muscles contract, they release ‘hope molecules’ (myokines) such as IL-6 and irisin. These proteins then travel through the bloodstream to reduce inflammation, improve insulin sensitivity, and even support brain repair. This piece illustrates how movement triggers a systemic healing cascade throughout the human body.

Explore the efficiency of photosynthesis under various conditions

In this simulation, users can track how the cellular concentrations of ATP, NADPH, glucose, and oxygen vary over time in response to changes in temperature, acidity, carbon dioxide concentration, and the properties of incoming light. Through multiple trials, users can identify the optimal conditions for photosynthetic reactions.

Endurance art strains and exhausts the body

Artists like Marina Abramović are known for testing the limits of human endurance. Endurance art can involve carrying heavy objects or posing uncomfortably for long durations. (This resource contains some artistic depictions of violence.)

How does muscle memory work?

Muscle memory is less about remembering how to ride a bike and more about what's happening in muscle cells. Increasing the cells' size, say by working out, leads to an increase in nuclei, which increases the production of mitochondria. When your fitness regimen falls to the wayside and you decide to re-enter the gym, these gains-based nuclei are already present to quicken muscle cells' adaptation to exercise.

Metabolism, a collection of chemical reactions at the cellular level, processes food and converts it into energy to power the body.

Stroke risk doubles each decade after age 55

While age is the greatest risk factor, genetics, diet, and overall health play a prominent role in determining individual stroke risk. Prevention focuses heavily on modifiable risk factors. High blood pressure is the single most important controllable risk factor, contributing to both types of stroke.

The exercise sweet spot is shorter than you'd think—and longer workouts aren't generally better.

Exercise can change your genes without changing your DNA.

Aging explained with Dr. Nick Golinvaux

Aging is more than wrinkles and gray hair—it’s a gradual decline in cellular function. Over time, DNA damage, telomere shortening, and mitochondrial inefficiency contribute to weaker bones, slower memory, and reduced vitality. While aging is inevitable, regular exercise, quality sleep, and stress management maintain health and extend one’s years.

Targeting cholesterol metabolism may help address macular degeneration.

'Viscoelasticity' allows muscles to be elongated briefly after stretching

The protective tissues around skeletal muscles consist of elastic proteins like collagen. Stretching them expands their length while retaining strength, ideal for athletes.

The human brain only uses 5% more energy during active tasks versus resting

Despite only being 2% of the weight of a human body, the average adult brain consumes 20% of its energy, with the majority of it spent on maintaining homeostasis—the stable equilibrium conditions of temperature, acidity, blood sugar, and other properties in the body. For infants, the consumption is closer to 50%.

Exertional heatstroke is a leading cause of death among athletes and soldiers in training, and typically occurs when someone sweats intensely while exercising in the heat.

Oxygen is produced in the International Space Station from recycled water, which is split into hydrogen and oxygen gases using an electric current.

Using fitness wearables to track muscle wasting in astronauts

All that exercising, and astronauts still are likely to lose a large amount of muscle mass while in microgravity. Astronauts can lose up to 20 percent of their muscle in as little as five days in space. Currently, tracking muscle loss means waiting until astronauts land to remeasure their muscle density post-trip. This article explains a NASA-backed fitness wearable that may be able to track muscle atrophy as it happens.

The flashing green light on a smartwatch estimates a person's heart rate by measuring the amount of light reflected back to the watch as blood vessels expand and contract.

Adults need 2 days of muscle-strengthening activity weekly—yet most of us aren't doing that.

While nearly all fish are cold-blooded—their body temperatures match their surroundings—the opah, or moonfish, is fully warm-blooded, with a body temperature about 5 degrees Celsius (9 degrees Fahrenheit) warmer than its environment.

World records are often broken later in the day—and scientists wonder if muscle clocks explain the difference.

Yoga can be beneficial for aging practitioners

Studies suggest that yoga can help alleviate several diseases associated with aging by lowering blood pressure, reducing blood fat levels, and combating obesity. It has also been shown to increase telomerase activity, which helps slow cell aging.

Biological aging tests assess the breakdown of physiological systems

Known as aging clocks, these tests compare various metrics, like DNA methylation patterns and protein profiles, to healthy baselines. However, the non-uniformity of these baselines across individuals limits testing accuracy and prevents their clinical use.

Donated hearts remain viable three times longer now with new tech

Advances in organ perfusion systems have significantly lengthened the amount of time donated hearts can remain viable for transplant, expanding the possibilities for donor organs to wider geographic areas. "Heart in a box" devices, developed in recent years, enable effective oxygen flow in the donor heart during transport, which means that hearts can now travel farther to potential recipients and still be in good condition.

A caffeine calculator

This simple calculator takes your preferred caffeinated drink and your body weight to determine how much is the right amount, and how much might kill you. In case you've ever had the morbid curiosity about just how much of that tea you'd have to drink to doze off forever. Find out your moderate and lethal doses here, as well as some extra info on caffeine consumption.

How trauma gets ‘under the skin’

A study examining the muscle function of older adults who have at least one adverse childhood experience (ACE) suggests that trauma digs itself into muscle cells. Participants who reported childhood trauma were found to have lower maximum levels of cellular energy than people who reported fewer or no ACEs. Such compromised mitochondrial function "doesn't bode well," as it relates to a variety of health and age-related outcomes.

Watch Kipchoge break 2 hours in the marathon

The feat was once considered impossible, but one of the world's greatest marathoners got to work (with the help of a team of scientists and some of the world's most elite distance runners) to break that boundary in Vienna in 2019. The final stretch of the run is an emotional moment for Kipchoge, who doesn't even appear to be winded.

Olympians view sleep as a performance tool, prioritizing routine and environment

Elite athletes emphasize consistent sleep routines, dark and cool environments, the well-placed nap, and tools like eye masks, white noise machines, and supplements like melatonin (particularly for jet lag). This priority belies a core principle: recovery and performance are inseparable. Read more ways Olympians "sleepmaxx" here.

Moving your body every day is key to longevity

In an era of biohacking, where millionaires subject themselves to draconian routines and tests to de-age themselves, one study suggests a super simple key predictor of mortality: more than any other trait, how much subjects moved determined how long they'd live. Movement mattered even more than age in predicting overall life longevity. Researchers suggest this means we should all simply get outside a bit more. Read more about the study here.

Adults may lose roughly 3% of their muscle mass each decade after 30.

Viscosity is a fluid's resistance to flow, which varies with temperature

Liquids become less viscous as temperature increases, while gases become more viscous and therefore flow more slowly. The increased gas collisions at higher temperatures contribute to greater friction between streamlines, increasing viscosity.