Metabolism, a collection of chemical reactions at the cellular level, processes food and converts it into energy to power the body.

How does your body turn food into energy?

Cells get energy via a process known as cellular respiration, which involves turning glucose into ATP or adenosine triphosphate. Breaking the phosphate bonds of ATP results in usable energy being released into cells, which can then use that energy to power biological processes. This 10-minute video explains how glucose turns into ATP, giving the body the energy it needs to survive.

Is metabolism related to weight loss?

Read this article to better understand metabolism and why doctors say it's only one piece in the puzzle to managing weight. Metabolism breaks down and converts what we consume into energy, which provides fuel for all of our body's functions—both...

Take a 360-degree look at biochemical activity from within a human cell

In this tour, users can observe the dynamic processes that occur within the basic units of the human body, including the production and transport of proteins and the assembly and disassembly of microtubules—thin, cylindrical structures that provide structural support and a means of moving material within the cell.

Spontaneous metabolism may give clues to origins of life

Read this article to learn more about the discovery that suggests that metabolism could have begun spontaneously on our planet—and why it means that scientists may need to rethink how we define life’s origins. A team of researchers at the...

Cells can last in the human body from days to a person's entire life

Despite claims that a person's body replaces itself every seven to 10 years, the rate at which cells die and are replaced varies by cell type. Gastrointestinal cells that line the digestive tract and stomach last only a few days, while some heart muscle cells and most neurons are around from birth until death.

What is metabolic rate?

Read this article to better understand the concept of metabolic rate, which is defined as the amount of energy expended by an organism over the course of a day. Basic metabolic rate (or BMR) is this metabolic rate at rest, during which the body only...

Complex molecular reactions in our tissues cause muscle contraction

When we want to move a muscle, a signal travels from the brain and into the muscle cells in question, sparking a chemical reaction that causes the muscle's smallest contractile units—sarcomeres—to shorten, forcing the muscle to contract.

An explanation of the Calvin cycle, including why it needs to run six times to create glucose

Each run of this second phase of photosynthesis begins with a five-carbon molecule called RuBP, which gains an additional carbon atom when carbon dioxide (CO₂) is attached. Across six cycles, the six six-carbon molecules—36 carbon atoms in total—are processed into 12 three-carbon sugars, which can be used to generate glucose, and six RuBP molecules, enough for each cycle to restart.

An overview of oxygenic photosynthesis, which releases oxygen from breaking down water

Within the membranes of chloroplasts, electrons in pigments are energized by light and transferred across a series of molecules until they create the energetic NADPH molecule. This transfer also powers a hydrogen pump, which creates an ion imbalance that, when relieved, produces energetic ATP molecules. Outside the membranes, both NADPH and ATP are used to synthesize G3Ps, which are funneled into other metabolic pathways to produce sugars.

Most cells undergo programmed, controlled death

In the average adult human, apoptosis occurs in 50 billion to 70 billion cells daily when proteins managing a cell's life cycle send signals that the cell is damaged, causing it to break apart into smaller pieces that are consumed by white blood cells. The consumption prevents damage from spreading via cell division.

Cells create more organelles and duplicate their genetic material before dividing

As part of the cell cycle, this ensures that after mitosis—the process of cell division—the two resulting daughter cells possess the tools necessary to complete the functions of their parent cell, including accumulating energy and making proteins. During meiosis, four egg or sperm cells are created, each with half the parent cell's DNA.

How humans digest food

Every day, the average human eats close to six pounds of food—all of which must be processed by the digestive system. Ten organs collaborate to transform food that the mouth chews into the energy needed to stay alive. (Stretched out, these organs...

Cellular aging and deterioration leads to tissue (and overall) aging

Cells are the building blocks of life, forming tissues and organs that keep our bodies working. As we age, cellular changes have progressive consequences on both the structure and function of our organs. This article examines this complex relationship as it relates to the incremental changes associated with aging.

On average, the human body produces about 100 watts of electricity—enough to power a light bulb—but some people can produce over 2,000 watts in short bursts, such as when sprinting.

Aging results from the cumulative breakdown of cellular and tissue processes

A cumulative breakdown of cellular and tissue processes combines to result in decreased organ function, disrupting the systems driving normal human physiology. This five-minute video provides a primer on the subject, complete with a discussion of risk factors, cellular changes, and potential future treatments in the fight against aging.

Imagining if humans could perform photosynthesis and how it would change our anatomy

Since chloroplasts reflect green light, becoming photosynthetic would give our skin a green appearance. Because photosynthesis has efficiencies of only 5% to 9%, and humans burn 2,000 Calories daily compared to about 200 burned by a tree, becoming photosynthetic would also require us to adopt a less active, sun-filled lifestyle.

Each second, the human body produces 2 million to 3 million new red blood cells.

Photoautotrophs, which include plants, algae, bacteria, and Euglena, are organisms at the base of the food web that convert light energy from the sun into chemical energy stored in sugars.

Cells cannot grow forever due to escalating inefficiency in transporting chemicals

As cells get larger, their volume grows much faster than the surface area through which nutrients and waste products pass, creating a bottleneck that eventually causes cells to die. This forces nearly all organisms visible to the naked eye to comprise enormous numbers of smaller cells, such as the approximately 30 trillion found in the average adult human.

Some organelles are believed to have once been independent cells

Mitochondria and chloroplasts, which are both responsible for energy production in cells, have DNA distinct from that of their host cells and are surrounded by cellular membranes resembling those of bacteria. Through symbiogenesis, these and other specialized structures were absorbed into larger cells, forming the modern-day biological units.

What is a cell? A great quick overview.

YourGenome.org furnishes a collection of information on cells and how they work. Every body has trillions of cells, each serving a specific function: making proteins, processing chemicals, and creating energy. Every cell contains a genome, a set of instructions for the cell's function. Brush up on your cells for a better grasp on genetics.

Stem cells can reboot the ability of cells to repair themselves

Stem cells—special cells that can self-renew and evolve into new cell types—may provide a path to address aging. Instead of repairing aging cells, stem cells can replace a cell's "repair kit," effectively rebooting the internal processes of tissues to a more youthful state.

Breaking down the challenges of alkaline environments and how extremophiles survive them

These areas are far less acidic than the interiors of most organisms' cells, and this imbalance draws protons that are needed for various metabolic processes, including energy production, out of cells. To counter these effects, some alkaliphiles have developed stronger proton regulation across their cellular membranes and proteins that drive these processes with greater stability amid such acidity imbalances.

Rubisco, the crucial enzyme powering photosynthesis

Photosynthesis is the crucial process by which plants absorb sunlight, take up water, and breathe in carbon dioxide, prompting chemical reactions that result in the byproducts sugar and oxygen. A key enzyme, rubisco, is responsible for it all, but it is inefficient. This video explores the key protein and reveals fascinating facts about oxygen and photosynthesis.

While most cells possess DNA, red blood cells destroy their nuclei to maximize the amount of oxygen they carry and more easily alter their shape to fit through narrow blood capillaries.

Learn about historical uses of bioremediation, the oldest cleanup method on Earth

Biochemical reactions that decompose complex molecules into simpler ones have occurred on Earth for as long as life has existed and have gradually transformed the planet into a celestial body that is increasingly habitable to greater biodiversity. Along the way, modern, human-made bioremediation techniques began to take shape in Santa Maria, California, in the 1960s.

Human anatomy 101: the body's systems

Human life is made possible by the body's ten major systems, which maintain homeostasis by responding to incoming sensory and biochemical input. Each system must work independently and collaboratively for the body to maintain health and respond appropriately to its internal and external environments. The bones of the skeletal system, for example, give the body its shape and protect organs while also facilitating movement with the muscular system.

Bone marrow generates roughly 500 billion new blood cells each day.

Catalysts increase chemical reaction rates by providing a lower energy pathway

All chemical reactions must overcome an energy barrier, called an activation energy, to proceed. If insufficient thermal energy exists in the system to overcome the barrier, catalysts can effectively lower the activation energy, increasing the likelihood of reactions occurring.

Single-cell organisms have circadian clocks that direct daily biochemical routines

Cyanobacteria, a type of light-sensitive bacteria, use this clock to signal when to alternate between making organic compounds through photosynthesis and when to convert atmospheric nitrogen into usable ammonia. Upregulating photosynthetic machinery before dawn helps ensure efficient photosynthesis.

Can we speed up our metabolisms?

Listen to this 31-minute podcast to better understand what science knows and doesn't know about metabolism, as well as the only thing that seems capable of changing it. Scientists understand that the difference between a so-called “fast” and “slow” metabolism does not affect one’s ability to lose weight.

In 2026, researchers at the University of Minnesota created the world's first synthetic cell—a cell made from non-living chemical components—that can eat, grow, divide, and compete with other cells for resources.

New blood cells are created by hematopoietic stem cells

Blood is made up of several cells with various functions and short lifespans, so the body must have a constant supply of replacements. These replacements are created by hematopoietic stem cells, rare cells that live in bone marrow and can regenerate themselves and blood cells.

Why the abundance of RuBisCO in photosynthetic cells may come from its inefficiency

Despite pulling about 115 billion tons of carbon dioxide from the atmosphere to build organic molecules each year, the enzyme instead binds oxygen at least one in five times, needlessly costing cells energy. To compensate for this and its processing of no more than 10 molecules per second—versus thousands processed by a typical enzyme—it's become the most abundant enzyme on Earth.

Synthetic biology transforms cells into custom DNA foundries

At companies like Ginkgo Bioworks, researchers are reprogramming cells to act as workshops that can create custom molecules, such as medicines and fertilizers, by stitching together DNA sequences—often in novel combinations—before inserting them into an organism's genome.

The chlorophyll in plants captures energy in the form of red and blue light

Light-dependent reactions during photosynthesis convert sunlight into chemical energy, stored within the bonds of molecules such as ATP and NADPH. Rather than being absorbed for these reactions, most green light is reflected, causing most plants to appear green.

Aging is a complex biological process affecting our cells, tissues, and organs.

Explore how cells respond to signals from their environment

In "Dropping Signals," users can drag stimuli, such as hormones and light, into various cellular environments to observe cellular responses. These include changing their shape, enabling the transport of chemicals into or out of the cell via the cell membrane, or dividing to compensate for surrounding damaged cells.

'Endoevolution' refers to the Darwinian selection happening continually inside us

The term, coined by Roxanne Khamsi in her 2026 book "Beyond Inheritance: Our Ever-Mutating Cells and a New Understanding of Health" describes the idea that evolution does not just occur across generations of humans. Instead, mutated cells continuously compete with healthy ones in our bodies, with implications for our tissues and health. Khamsi says these autocorrections are essentially natural gene therapy. 

Watch DNA replicate itself before cell division

In the average adult human, between 50 billion and 70 billion cells die daily, requiring them to replicate their genetic instructions before dividing into new cells. This process relies on various proteins to unwind, read, build, and proofread new strands, with error rates of fewer than one per 1 billion nucleotides.

Muscles fatigue due to the loss of energy like ATP and glycogen

Adenosine triphosphate fuels muscle contraction, and with each contraction (like during exercise), the amount of ATP reduces. ATP helps potassium and sodium move across muscle membranes, generating ions and helping to contract the muscle.

See this 201-level explanation about mitochondria and mitochondrial replacement therapy

This 2022 academic presentation from Stanford University's Dr. Gregory Enns offers a detailed overview about mitochondrial therapy approaches. Enns, a pediatric geneticist, explains how well-functioning mitochondria support the human body.

Scientists can tag distinct proteins with fluorescent probes that emit different colors, allowing them to visualize multiple biochemical processes simultaneously.

The three categories of photosynthesis, which each help plants survive in different environments

In the vast majority of plants, C3 photosynthesis produces three-carbon intermediate molecules in the Calvin cycle within the cells of leaves. Plants in hot, dry climates use C4 photosynthesis across two types of cells to produce four-carbon molecules before the Calvin cycle. Plants in drought conditions use CAM to store carbon dioxide as an acid at night, minimizing water loss.

How brain cells carry information

At any moment, there is an electrical storm coursing through your body. Discover how chemical reactions create an electric current that drives our responses to everything from hot pans to a mother’s caress.

Instead of consuming water and carbon dioxide to produce oxygen and sugar, anoxygenic photosynthesis involves alternative reactants and products.

What does blood do?

Blood's primary purpose is to ferry oxygen and nutrients to cells in need while collecting cell waste and byproducts for removal. It also enables the body's repair and immune systems to traverse our internal landscape to address cell damage or external invaders, such as viruses and parasites. Zooming out from the exact roles of blood's various cells, the fluid connective tissue also assists with maintaining homeostasis via temperature regulation and pH balance.

What do vitamins actually do?

Vitamins are molecular tools the body needs to carry out regular cellular processes, such as wound healing. This 45-minute video dives into the science behind vitamins and their role in the body. There are 13 essential vitamins that must be...

Understanding the role of photosynthesis as a sink within the carbon cycle

Photosynthetic organisms are net carbon absorbers, pulling carbon dioxide from the atmosphere and storing it in organic compounds and within soil. Approximately one-third of humanity's carbon emissions are stored by these organisms.

Explore the efficiency of photosynthesis under various conditions

In this simulation, users can track how the cellular concentrations of ATP, NADPH, glucose, and oxygen vary over time in response to changes in temperature, acidity, carbon dioxide concentration, and the properties of incoming light. Through multiple trials, users can identify the optimal conditions for photosynthetic reactions.