There's a goddess in South Asia worshipped for her protection against cholera

We're in the middle of a decadeslong cholera pandemic

In 1961, the world's seventh recorded cholera pandemic started in South Asia, and it has continued through the decades. India and Bangladesh are at particular risk. This pandemic is driven partly by conflict, population displacement, extreme weather, and poor water infrastructure.

Cholera vaccines can protect people from disease for months—or even years

There are three recommended cholera vaccines on the market. The number of required shots and the period of protection they provide vary, but each of them can be life-saving.

Historically, cholera has repeatedly disrupted the Hajj for Muslims

Outbreaks of the disease throughout the 19th century and the beginning of the 20th, killed thousands of religious pilgrims as they sought to complete this obligatory pilgrimage.

About 20% of people infected with cholera have severe symptoms

That's according to studies from outbreaks in Bangladesh. Most people who contract the disease have mild or moderate symptoms, or none at all. Yet anyone infected with the disease-causing bacteria can shed the pathogens in their feces for a few days, or even up to around 10, seeding the environment with bacteria.

Cholera went global thanks to global trade

The first cholera pandemic grew from an outbreak in India, in 1817. Scientists suggest it spread from there throughout the continent and onward to Africa, Russia and Europe through the poop of traders.

More than 4,000 people died from cholera in 2023

This global health threat sickened more than half a million people in 2023 and killed 4,007 people. That's a 71% increase in deaths as compared to a year earlier. (Report only offered in PDF format.)

The wonderfully named Vibrio diabolicus is a cousin of the cholera-causing bacterium

This bacterium, which belongs to the same genus as the cholera bacterium, was initially isolated from deep-sea hydrothermal fields. It was sampled from water that was scooped up during a French-American cruise in October 1991.

1 in 4 people around the world don't have access to clean water

Poor water sanitation puts people at risk of acquiring this diarrheal infection. Cholera infections are on the rise due to extreme weather events and conflict. In recent years there have been cholera outbreaks in locations that hadn't seen the disease in many years, including Haiti.

See how cholera spreads in a community

This animated video offers a comprehensive look at how cholera spreads. It makes clear why it's so difficult to stamp out this disease in communities around the world. It also details what steps can help control cholera.

Learn how cholera bacteria sicken humans

Once a person has ingested large amounts of the bacteria, typically through contaminated water, cholera bacteria begin producing and releasing a toxin inside their host. It attacks the mucosal lining of the intestine, making it hard to absorb liquids. This process leads to cholera's characteristic symptoms, like voluminous, watery diarrhea.

Cholera can persist in the environment, unlike smallpox, which needs a human host

Vibrio cholerae is the pathogen that causes cholera. It can reproduce in the environment without a human host, which means it's formally called a facultative pathogen. Obligate pathogens need a host to reproduce. Examples of obligate-based diseases include leprosy and smallpox.

Extreme weather conditions heighten cholera risks in settings like refugee camps

Runoff from sewage—exacerbated by situations like flooding or extreme rains—heightens this threat. Increasing temperatures also create the ideal conditions for the bacteria to reproduce, increasing transmission risks.

Oral rehydration solution was developed in the 1960s in response to cholera deaths.

In 1892, two scientists purposefully infected themselves with cholera bacteria

When they became ill—one with mild diarrhea and the other with severe cholera—researchers pointed to that as proof that the pathogen caused the disease.

A comprehensive guide to the gods

History is filled with the power and mystique of gods, from the epicly bearded Greek boss Zeus to Hoori, the Japanese god of hunting. Check out this database of over 4,000 of the world's deities, from Norse mythology to the gods of Polynesia, and click through for explainers and facts. Peruse specific pantheons (a single culture's collection of gods) or look for the god of a specific attribute, place, or emotion. Dive in here.

The prophetic Oracle of Delphi was believed to have a direct line to the Greek god Apollo.

Cholera was called the 'Blue Death'

In the mid-1800s—when John Snow identified cholera in London—the disease was known simply as the "Blue Death." That's because blood would thicken in patients' veins when they were struggling with extreme dehydration. As a result, their skin would turn a blueish hue as their blood was starved of oxygen.

The cholera bacteria was first isolated in 1854—but the discovery was largely ignored

The pathogen was isolated by the Italian physician Filippo Pacini in Florence, Italy, though his discovery was largely ignored in favor of the popular miasma—bad air—theory of disease at the time. The pathogen was separately isolated about three decades later by German microbiologist Robert Koch.

The canal carried germs as well as goods

In 1832, North America’s first cholera epidemic spread inland by way of the Erie Canal, carried by immigrants arriving on ships. Fearful towns barred passengers from disembarking, yet cholera, smallpox, and other diseases still traveled the waterway.

Maryland required cholera researchers to fly a yellow warning flag—signifying quarantine dangers in the 1970s

University of Maryland Hospital researchers intentionally infected volunteers with the cholera bacterium in the late 1970s to further their understanding of the disease. They proceeded with this work following the recommendation of a US government panel. (Some users may encounter a paywall.)

Unprecedented imaging of the Vibrio bacteria, published in 2026, may highlight new treatment targets

Researchers have produced the most detailed image ever of a key part of the Vibrio bacteria—the cause of cholera—known as the sheathed flagellum, which helps it move.

The Aztecs worshipped Mictecacihuatl, goddess of the underworld

Some elements from ancient festivals honoring Mictecacihuatl and other deities, like incense, skeleton imagery and marigolds, have been incorporated into modern Day of the Dead celebrations, possibly indicating that the holiday blends indigenous and Catholic traditions.

Egypt's pantheon is the result of a thousand years of myths

Their pantheon consisted of nearly 2,000 divine beings which evolved over time, led by the broadly worshipped sun god Ra. Many of the myths surrounding each god changed dramatically or even intertwined with others as cult followings grew popular or shifted from city to city.

The role of textiles in South Asian art

Textiles play an essential role in the religious traditions of the Indian subcontinent, acting as portable shrines that can relay important allegories and depict spiritual iconography. This primer from Smarthistory breaks down how imagery is used on these textiles and helpfully provides high-quality images, allowing you to witness their beauty for yourself.

Wastewater testing has detected genetic evidence of polio, triggering vaccine boosters

Sampling of wastewater in London in 2022 detected fragments of polio virus, suggesting a vaccine-derived version of polio may be circulating. No one became ill, but the finding did trigger calls for a renewed booster inoculation campaign.

Climate shifts are projected to cause more cases of food poisoning

Research published in 2024 suggests that with more severe heatwaves and natural disasters, scientists expect there to be a rise in foodborne disease, especially in Africa and Asia. Already, there are an estimated 600 million food poisoning cases and 420,000 deaths annually. Diarrhea is the most common cause of those deaths.

Ofrendas are memorial altars constructed to honor deceased loved ones

Each element of the altar is meaningful. There is food and drink to nourish the spirits on their journey, candles to light their way, and incense to protect against evil spirits, among other things.

Researchers have investigated the benefits of extreme pain rituals, exploring how and why we engage in these events when humans generally naturally avoid pain and perceive it as a negative experience.

Matrilineal societies—where women led households—were common among Northeastern natives

Such societies also viewed women as leaders in spiritual matters. Both men and women held political roles as clan leaders and worked in tandem with an advisory council.

Day of the Dead is celebrated across the world

While almost all celebrations involve cemeteries and altars, many countries also have their own unique traditions, including Bolivia’s staircase-shaped bread to help lead souls to heaven, and Haiti’s voodoo-influenced rituals.

Kulfi, an ice cream predecessor that's still popular in South Asia, dates back to the 16th century.

Learn how the Egyptians, Romans, and other ancient civilizations worshipped the sun

In Egypt, the pharaoh was seen as the living embodiment of the son of Ra, the sun god. In Mesopotamia, the sun god Shamash was a divine judge whose light could reveal the truth. Huitzilopochtli, the Aztec god of sun and war, was thought to require sacrifices to prevent the universe's destruction.

Acetabularia jalakanyakae is one of the largest known single-celled organisms and is nicknamed the 'mermaid's wineglass' for its umbrella-shaped cap.

Even in recent history, adaptations to the environment drove human evolution

Through genetics, environmental pressures, and cultural influences, humans have evolved to tolerate lactose, develop varying skin pigmentation, and acquire genetic resistance to diseases like bubonic plague. The metabolic and digestive systems of Indigenous peoples have adapted to their diet, which is influenced by the availability of food and water.

The Aztecs worshipped a vast pantheon of more than 200 gods.

‘Namaste’ was popularized in the English language after India gained independence

The word, which roughly translates to “I bow to you,” is a greeting often used in yoga. The word began appearing in American publications more frequently following the country’s liberation, and was standardized shortly thereafter.

Hippocratic doctors treated severe mental illness with the poisonous plant hellebore

Since symptoms like hallucinations were believed be due to an imbalance of black bile, yellow bile, blood, and phlegm, the treatment at the time was to bring those humors back into balance. That meant standard treatments could include bleeding a patient or using substances like hellebore to induce vomiting or diarrhea.

'Sloth fever' is an emerging health threat, especially to pregnant women

This disease, caused by the Oropouche virus, is found in animals including sloths, primates, and birds. It primarily spreads through the bite of midges—insects commonly called "no-see-ums." It's endemic to the Amazon region, but US travelers are increasingly contracting it internationally.

Some parents have objected to yoga in schools

Yoga has been introduced in some public schools as a form of exercise and emotional regulation. Some parents, however, have objected to its inclusion, arguing that it promotes the Hindu and Buddhist religions. Note that this resource will be paywalled for some readers.

Polio commonly spreads when virus-laden feces gets into our mouths

This highly infectious disease is transmitted from one person to another, mainly when we eat virus-laden poop particles. Less frequently, contaminated food or water can transmit the virus, or people can be infected via respiratory droplets (from coughing or sneezing).

Traveling yogis spread the practice across the US

After a 1923 Supreme Court decision ruled that Asians were ineligible for citizenship, many South Asian immigrants had relatively few job opportunities and began moving around the country teaching yoga and spirituality. At the time, yoga was viewed less as a physical practice and more as a mystical one, something many of the teachers embraced to attract students. South Asians regained the right to citizenship in 1946.

What is salvia divinorum?

After centuries of use by Mexican spiritual healers, Salvia divinorum is surging in popularity in the U.S. — and the government has taken notice.

What ghosts eat around the world

This Thrillist article compiles a rich assortment of cultural beliefs and practices surrounding food for the dead. From Bengali folklore to Ancient Greek mythology, peruse through the different ways in which cultures around the world use food to maintain connected to the deceased.

View a map of countries with the safest and most dangerous drinking water

More than a quarter of the world's population lives in water-stressed countries, and a similar number use contaminated drinking water sources, which can lead to widespread disease, according to the World Health Organization. The Environmental Performance Index shows which countries have safe drinking water.

Paris and Boston were redesigned partly to combat cholera's spread

Georges-Eugène "Baron" Haussmann, who oversaw Paris's redesign in the 1800s, replaced many of the city's narrow streets with wide boulevards. This was done at least in part to bring more air and light into the city to help control cholera. Architect Arthur Gilman redeveloped Boston's Back Bay to similarly combat cholera, among other reasons.

Robert Koch won the Nobel for his tuberculosis work, but he also pioneered cholera research

Koch was one of the first scientists to isolate the bacterium that causes cholera while investigating an outbreak in Egypt in 1883. He went on to advise about rules to control cholera outbreaks, which formed the basis of the disease control approaches and water hygiene techniques still used today.

A family's yearslong poisoning

Over 14 years, a southern Indian family slowly lost six members, several of whom were found foaming at their mouths. Upon the third death, a post-mortem examination was requested, revealing cyanide had been ingested, though it was ruled as self-inflicted. Several will edits and three deaths later, relatives turned a critical eye toward Joliyamma "Jolly" Joseph, who had married into the family and been present at each death.

Pooping or puking out pathogens is sometimes recommended with food poisoning

Sometimes stopping food poisoning-linked diarrhea with over-the-counter medications is a bad idea because it may prolong illness. Doctors can advise you if your diarrhea or vomiting is severe about what medications to take and when, but generally doctors recommend trying to stay hydrated during a bout of food poisoning and letting the body naturally remove pathogens from the body via vomiting or diarrhea, as needed.

Hear what it's like to have malaria from a patient who suffered from the mosquito-borne disease.

Practices and beliefs from Hinduism, Buddhism, and Jainism influenced yoga

Yoga scholars Mark Singleton and James Mallinson’s study, “Roots of Yoga,” collects over 100 core texts on the subject. They found that many different ethnicities and religions practiced yoga in antiquity; Singleton says that the practice was a “floating technology between various religious systems.”