Each scientific study adds incremental knowledge to existing understanding

Scientific progress works toward absolute truth, but can never reach it

Through the acquisition of scientific knowledge, scientists construct explanations of the world, which are rigorously tested and verified until they narrow down to a leading theory of the natural world. However, because of how science works, these ideas will never become factual, as they must always remain open to be iteratively revision based on new data.

Science is rarely a linear progression of understanding

Particularly at the frontiers, investigations conducted based on established knowledge can provide unexpected results. This opens the door to revising existing models, inspiring new lines of research, and ultimately leading to better future comprehension. For instance, experiments on the speed of light and the expansion of the universe yielded then-confusing data that led to revolutionary insights.

Distinguishing between scientific theories and laws, and why both are on equal footing

Scientific laws describe outcomes of specific conditions, and scientific theories explain why those outcomes occur. Both are supported by observational and experimental data and can each inform one another, but neither can become the other. Instead, additional data can improve each towards more accurate descriptions and explanations of reality.

How facts, hypotheses, theories, and laws in science differ from everyday language

Facts are observations of the world, and they can be pooled together for a given phenomenon to develop a hypothesis—a proposed explanation consistent with observations that requires further investigation. Experiments and additional data can rule out many hypotheses or graduate a proposed explanation into a widely accepted and validated theory.

Learn why modern scientific patterns have been described as theories rather than laws

After confirming that the accuracy of some laws of physics is limited to certain domains, science became more hesitant to categorize identified mathematical relationships, such as quantum mechanics, as unchanging laws. Instead, these recent, complex frameworks are designated as theories to acknowledge that they are conditional and may be part of a larger, more complete future framework.

Humans experience the world subjectively. What does that mean for scientific research?

When you close your eyes, do you see static or colorful patterns or an "intrinsic grey" known as Eigengrau in German? This variation of our internal experiences is just the tip of the iceberg, one that scientists are increasingly studying and...

Research suggests articles on Wikipedia are about as reliable as 'accurate' sources

Studies from Nature, The Guardian, the Journal of Clinical Oncology, and the Canadian Library Association, among others, did not identify significant errors, particularly in articles related to academic topics. The site is still considered an exploratory, tertiary source subject to systemic biases from its human editors, especially within controversial topics.

Support groups can offer insights into current and potential treatments

Beyond connecting with patients with similar experiences, support groups can also become centers for advocacy and for sharing research advances and medical experiences, including potential side effects from novel therapies or clinical trials.

Research studies can be conducted inside or outside of living samples

While "in vitro" experiments occur outside living organisms for cost-effectiveness, "in vivo" experiments take place inside them, providing real-life insights at a higher cost and with increased ethical concerns. Alternatively, "in silico" methods use computational simulations.

Explore a series of interdisciplinary explainers on climate science

From animations on the quantum mechanics of greenhouse gases to a photo essay on how scientists acquire climate data, this collection provides detailed explorations of how different branches of science have contributed to our understanding of climatology.

Why being able to disprove explanations distinguishes scientific theories from pseudoscience

Introduced by philosopher Karl Popper, falsifiability holds that a scientific theory must make predictions that could be proven inaccurate by future observations. Explanations that cannot make such predictions are not scientific theories. It is scientists' jobs to seek out data to poke holes in scientific theories, thereby potentially strengthening them if they hold up to scrutiny.

How to build curiosity

Change and uncertainty induce stress, but reframing the unknown into an opportunity for discovery has tangible benefits. Approaching change with curiosity enhances activity in the hippocampus and promotes neuroplasticity, promoting learning and serving as a barrier against anxiety. A neuroscientist explains how embracing the unknown, trying small experiments, and other techniques build curiosity.

How upheavals in accepted scientific theories helped popularize the term 'paradigm'

When Thomas Kuhn published "The Structure of Scientific Revolutions" in 1962, he described the history of science as comprising periods of "normal science" where these accepted frameworks—paradigms—gradually accumulate anomalies until they cannot describe nature. Revolutionary science, such as the development of a new theory, results in a paradigm shift, another term Kuhn helped popularize. (Some readers may experience a paywall.)

Studies of psychedelic use may help shed light on the nature of consciousness

The nature of consciousness—what it is, where it comes from, and how it manifests as moment-to-moment experience—remains under debate by scientists. Recent studies show psychedelics were found to boost low-frequency brain signals known as delta waves, a behavior also seen during dream states.

A technical review of what researchers know about the gut microbiome

This overview from the National Institutes of Health provides a deeper (but still accessible) look at the different bacteria in the gut, how the microbiome develops through life, its purpose, and more.

Search this citation-heavy database of nutrition and supplement research

Explore a reference site that aggregates and summarizes peer-reviewed studies on hundreds of supplements and dietary interventions. It is ad-free and funded by subscriptions, making it a health resource without a financial stake in what you buy.

What's next for gut microbiome science?

A Stanford microbiologist explores what we don't yet know about the gut microbiome—such as whether we can engineer the bacterial species within it—and the current scientific advances in the field.

How do scientists study far away stars?

Astronomy is the only science that is purely observational: meaning, scientists can't study stars in a lab. Here's a breakdown of how modern researchers use new tools to understand objects billions of light years away. As it turns out, the rules of science allow us to identify, categorize, and experiment with phenomena light years away.

Advance genetic research by playing these scientific video games

Computers produce so much information that researchers can't properly analyze all the data produced, and the overload can also lead computers to make mistakes. Researchers are increasingly turning to citizen scientists—members of the public who are willing to volunteer—to help them make sense of data when computers can't. This article details a few of the ways you can contribute to genetics research by playing video games.

The science of addiction treatment

A helpful resource from the National Institute on Drug Abuse (part of the NIH). This article examines addiction treatment and recovery through the science behind several accepted methods. The guide draws helpful comparisons with other chronic disease treatments. In particular, it discusses the overlap between medications and therapeutic treatments, and the understanding that relapse doesn’t indicate treatment failure—only a need for continued or modified care.

Learn the history of food science breakthroughs from the 20th century

Long after humans developed the means to produce sufficient food to feed civilizations, scientific research focused on a wide variety of objectives, such as developing methods to preserve food quality (accomplished via frozen food), speeding up cooking (leading to the microwave), and lowering the cost of sweetening food, which high fructose corn syrup provides.

What's the point of archaeology?

Archaeology as a science may seem focused on tangible goods, with its emphasis on material evidence of peoples long passed. But its findings influence how humans interact today (and possibly tomorrow). From understanding and improving on concrete to...

English chemist Rosalind Franklin (1920 - 1958) on the importance of science

"Science and everyday life cannot and should not be separated. Science, for me, gives a partial explanation of life."

Wikipedia openly displays edit history and editorial disputes to assess trustworthiness

Unlike a journal article, which may be reviewed by up to three people before publication, popular Wikipedia pages may be reviewed thousands of times by editors, potentially enhancing their reliability. Less reviewed articles still require reliable third-party sources and remain subject to verification by bots and administrators who can undo edits.

This 'Science Vs' episode checks the taste, health, and environmental claims about organic food against the actual research.

What does it mean for AI to "understand" something?

This Quanta article discusses how programmers are working to create a reliable test for the depth and extent of the knowledge of machines. What does AI know and how does it know it, if it knows anything at all? There's been progress, but it hasn't been easy. Even humans can still be fooled some of the time.

Browse the published volumes from the Pontifical Academy of Sciences—the Vatican's scientific advisory board.

As of 2022, about 40% of scientific research aimed at generating new knowledge has been funded by the federal government—a percentage that has decreased from a high of 72% in 1967.

Watch a video overview of the Pontifical Academy of Sciences, which advises the pope on science, from one of its Nobel Prize-winning members.

Recent evidence raises the question of whether conventional wisdom about amyloid plaques and their connection to Alzheimer's is wrong.

Scientific advances are unlocking a wide range of alternatives to IVF

From refined artificial insemination and microsurgical sperm extraction to experimental uterine transplants, scientific innovation is rapidly advancing potential fertilization technologies. But they come along with costly trials, some ethical dilemmas, regulatory issues, and more.

One data scientist argued that fan fiction improved writing

In an academic study, University of Washington professor Cecilia Aragon found that fan fiction often teaches young writers how to craft stronger sentences and convey complex ideas effectively. Much of that comes from the larger fan fiction community, which regularly comments on others' stories, offering kind-hearted constructive criticism in what she calls "distributed mentoring."

An overview of the National Science Foundation and the technologies it has helped fund

Established in 1950, the federal agency has provided billions of dollars to over 300,000 researchers, entrepreneurs, and students to conduct research across all seven continents. These funds have contributed to major technological achievements, from the invention of the internet to the first image of a black hole.

Although ecologists have struggled to identify a species as a keystone—one of outsized importance to its ecosystem—an analysis of 50 years of data and 157 studies identified 230 such species.

According to Bill Nye, science is under threat from an erosion in critical thinking

He states that conducting research online cannot replace consulting with scientific experts who have spent their entire lives intimately studying a field. The former science education show host argues that deepening cynicism towards scientific institutions has been fueled by leaders embracing debunked and unsupported claims.

Multiple new research paths may lead to slowing (or even reversing) aging

Aging has always been inevitable, but fasting, epigenetic reprogramming, and parabiosis seem to help people stay young. By studying centenarians, memory, and even the humble roundworm, scientists are looking for the genetic basis to live not just a long life, but a healthy one.

Scientists William Russell and Rex Burch proposed in 1959 that when it comes to animal testing, there should be 'three Rs'—replace animals wherever possible; reduce their numbers; refine how they're treated.

New ways of seeing the cosmos have redrawn the map of human identity

From Galileo’s crude spyglass to the James Webb Space Telescope, each technological leap has expanded our observational reach and redefined philosophical and moral conceptions of our place in the universe. Identifying signs of life through the study of exoplanet atmospheres would represent the next great revolution.

Two scientists argue consciousness evolved through 'unlimited associative learning,' the ability to learn almost any new pattern during a lifetime.

Problem solving, problem recognition, and learning ability makes up intelligence

Psychologists have several theories from which the concept of intelligence is explained, including general and multiple intelligences. Although IQ is used to quantify intelligence, issues like its cultural biases have spurred debate.

A quote by scientist Nikola Tesla

"The scientific man does not aim at an immediate result ... His duty is to lay the foundation for those who are to come, and point the way."

Browse a list of the most important scientific breakthroughs from each state

Although scientific discoveries involve experimentation, analysis, and collaborations among many individuals across a variety of locations, some observations, advancements, and breakthroughs have their origins in facilities within the US. These include the polio vaccine in Pennsylvania, the breathalyzer in Indiana, the observation of Pluto in Arizona, and the invention of nylon and Teflon in Delaware. (Some readers may experience a paywall.)

As of 2025, extensive research studies do not support fears about seed oils

Across human trials, seed oils have not been shown to increase rates of disease or inflammation, with a study of over 800 Swedish men finding that higher seed oil diets were linked to living longer. Reviews of these trials found better health outcomes when saturated fats were replaced with seed oils.

The study of dreams, formally called oneirology, has evolved over the centuries, from anecdotal interpretations to advanced brain imaging.

See a timeline of landmark discoveries in the field of genetics to gain a better understanding of more than a century of advances.

Social media can be a valuable public health tool, combating misinformation, advancing health research, boosting social mobilization, and raising awareness of health services and events.

Exploring the link between history, art, and anatomy

Throughout centuries, art has played a vital role in sharing—and furthering—scientific understanding. This largely began in 1543 when physician Andreas Vesalius worked with an artist and engraver to transform learnings from his dissections into...

Explore an interactive map of the unified theories of everything

This interactive concisely describes many highly complex theories ranging from quantum gravity and black holes to dark matter and energy. Supplementary resources, key questions, and possible solutions accompany each description. As of 2026, no developed theory provides an accepted explanation of all observed phenomena in the universe at all scales.

The field of attribution science seeks to determine whether specific phenomena, such as melting glaciers, droughts, and hurricanes, are driven by Earth's natural climate cycles or by human-caused climate change.

The Nobel Prize remains science's top honor despite limits and inequities

Each October, a few scientists gain global fame when told they’ve won a Nobel Prize—a century-old award founded by Alfred Nobel to recognize major achievements. While the prizes boost attention and prestige for winners, they exclude many deserving scientists due to rigid rules.