English chemist Rosalind Franklin (1920 - 1958) on the importance of science

Beyond DNA, Franklin's legacy extends into modern virology and steel production

While remembered for her critical but under-credited role in uncovering parameters for the structure of DNA, Rosalind Franklin made significant contributions across coal chemistry and virus structure. Her research helped improve fuel efficiency, wartime protective equipment, and foundational knowledge in molecular biology.

The woman erased from the DNA breakthrough

Rosalind Franklin captured “Photo 51,” the key to DNA’s double helix. Her data, shared without her knowledge, helped Watson and Crick win a Nobel. She never got the prize, but today, her role in unlocking life’s blueprint is finally recognized.

Rosalind Franklin’s work led to Nobel Prize-winning discoveries in DNA and virology

Her X-ray diffraction imaging helped uncover the structure of DNA, which earned James Watson, Francis Crick, and Maurice Wilkins a Nobel Prize. The same techniques enabled virus imaging, contributing to Aaron Klug's Nobel Prize in chemistry.

X-ray data from Rosalind Franklin was key to discovering DNA’s double-helix structure

Although unpublished, the data reached James Watson and Francis Crick, who worked at another institution. Incorporating her data allowed them to validate their model of DNA, which they published without crediting her.

Rosalind Franklin was the long-overlooked contributor to discovering DNA's structure

Though James Watson, Francis Crick, and Maurice Wilkins are credited with discovering the DNA double helix, it incorporated Rosalind Franklin's unpublished data. Photo 51, her famous DNA image, took more than 100 hours to produce and a year’s worth of analysis to interpret.

Science communicator Bill Nye (1955 - ) on science

"Science is the key to our future, and if you don’t believe in science, then you’re holding everybody back."

Polish chemist and physicist Marie Curie (1867–1934) on learning

“Nothing in life is to be feared; it is only to be understood. Now is the time to understand more, so that we may fear less."

Rosalind Franklin uncovered the molecular structure of the tobacco mosaic virus

Franklin's work revealed the role of ribonucleic acid in virus infectivity, contributing to a foundational understanding of genetics and virology. Her molecular model of the virus was featured as the centerpiece at the 1958 Brussels World's Fair.

Watson's book was described as misleading when detailing Franklin's role in DNA

Despite working together to win the Nobel Prize for their discovery of the structure of DNA, Francis Crick and Maurice Wilkins objected to the publication of James Watson's account of DNA's discovery. Those involved describe how he villainized Rosalind Franklin and downplayed her work.

Science is rarely a linear progression of understanding

Particularly at the frontiers, investigations conducted based on established knowledge can provide unexpected results. This opens the door to revising existing models, inspiring new lines of research, and ultimately leading to better future comprehension. For instance, experiments on the speed of light and the expansion of the universe yielded then-confusing data that led to revolutionary insights.

Explore a 3D model of the experimental setup Rosalind Franklin used to take Photo 51

To capture the X-ray diffraction image of DNA from the thymus of a calf, Franklin built a humidity-controlling camera to isolate the B form of DNA. The exposure lasted 60 hours and produced a cross pattern, indicating a helical structure.

A quote by scientist Nikola Tesla

"The scientific man does not aim at an immediate result ... His duty is to lay the foundation for those who are to come, and point the way."

Nature simultaneously published three papers on DNA—only the first made history

Papers by Watson and Crick, Wilkins, and Franklin were fast-tracked without peer review, and their order was arranged between lab heads and editors. Franklin's appeared last, making her paper read as though supporting Watson and Crick—because they'd already incorporated her data before it was published.

'Most of man's problems upon this planet, in the long history of the race, have been met and solved either partially or as a whole by experiment based on common sense and carried out with courage.'

-Frances Perkins (1880-1965), first female member of US Cabinet

Photo 51's distinct 'X' pattern and spacing provided data to validate DNA's model

Rosalind Franklin and Raymond Gosling captured the photo after bombarding DNA fibers with X-rays and observing how the beams were deflected. The photo had a 62-hour exposure time and indicated a helical structure for DNA.

The secret lives of cells

Cutting-edge microscopy has revealed previously unseen interactions of biological molecules within their cellular environment, enabling scientists to observe and analyze the molecules in a holistic view. This podcast explains the minute advancements made over the last few decades in observing cells, revealing how scientists have come and what the future holds for the field.

Italian physicist Enrico Fermi (1901–1954) on the Standard Model

"If I could remember the name of all these particles, I'd be a botanist."

Exploring carbon compound pore structures contributed to improved gas mask filtration

During World War II, the British Coal Utilisation Research Association sought to improve the efficiency of coal as an energy source and studied the effectiveness of charcoal filters to keep soldiers safe. Rosalind Franklin's research there formed the basis of her PhD and led to five scientific papers.

The history of chemistry up to World War I, from alchemists seeking gold to probing atomic structure

Those involved in the predecessor of the modern scientific discipline engaged in experimentation to develop recipes that would transform ordinary matter into gold and to create medicines, cosmetics, dyes, and alloys. Over the course of centuries, scientists identified unique elements, organized them based on their properties in the periodic table, and eventually developed the technology to discover the internal structure of atoms.

Quantum physics explained in 22 minutes

Brian Cox, Royal Society Professor for Public Engagement in Science, discusses the fundamental principles of quantum mechanics, emphasizing their importance in understanding the nature of reality and their practical applications in emerging technologies like quantum computers.

The term 'scientist' was coined in a 1834 book review by English polymath William Whewell, who needed an alternative to 'man of science' to describe Scottish writer Mary Somerville.

'Don’t try to be young. Just open your mind. Stay interested in stuff. There are so many things I won’t live long enough to find out about, but I’m still curious about them.'

- Actress Betty White (1922-2021)

As of 2026, the Pontifical Academy of Sciences, which advises the pope on scientific matters, has included 90 Nobel laureates among its members.

Oxford scientists turned Fleming’s mold discovery into medicine

In 1939, a team at Oxford—including Howard Florey, Ernst Chain, and Norman Heatley—revived Fleming’s forgotten discovery. Using makeshift equipment like bedpans and milk churns, they purified enough penicillin to prove it could treat deadly infections.

The Nobel Prize remains science's top honor despite limits and inequities

Each October, a few scientists gain global fame when told they’ve won a Nobel Prize—a century-old award founded by Alfred Nobel to recognize major achievements. While the prizes boost attention and prestige for winners, they exclude many deserving scientists due to rigid rules.

'The more clearly we can focus our attention on the wonders and realities of the universe about us, the less taste we shall have for destruction.'

- Marine biologist and environmentalist Rachel Carson (1907-1964)

The key ingredients to life on Earth—and elsewhere

Life can only arise in incredibly specific conditions, an abundance of certain substances like water and phosphorus, lots of time, and the right proximity to a heat-and-light-providing star. These two experts on evolution of life say above all, life requires luck. Here's a list of eight ingredients to life.

'How wonderful it is that nobody need wait a single moment before starting to improve the world.' - Anne Frank

Read an excerpt from 'The Immortal Life of Henrietta Lacks,' the story of the Black woman whose nonconsensually sampled cancerous cells underpin thousands of research papers and several Nobel Prize-winning works.

'The arts and sciences are avatars of human creativity. It's our attempt to influence things, the universe internal to ourselves and external to us.'

- Mae Jemison (1956-present), the first Black woman in space

'Fear of life closes off more opportunities for us than fear of death ever does.'

- Actress Agnes Moorehead (1900–1974)

The history of molecular gastronomy, from thickening yolks with alcohol to making art with food

Before understanding why they worked, humans used scientific principles, including designing solutions and analyzing outcomes, to develop preservation methods like curing meat and fermenting vegetables. By the 20th century, the application of industrialized food preparation to smaller kitchens set the stage for the subdiscipline of food science.

Critics say Nobel Prizes need updating to reflect how science and society work today

The rules still favor individuals over teams and may reflect outdated views on who does science. In 2013, the Nobel Prize in physics went to two theorists, even though over 5,000 scientists helped confirm the Higgs boson.

Marie Curie's research in radioactivity made her the first woman to win a Nobel Prize

Overcoming social and academic barriers, Curie's realization that radiation resulted from an intrinsic property of atoms reframed scientific understanding of the phenomenon. Her subsequent work in discovering two new elements—polonium and radium—earned her a second Nobel Prize.

'Imagination is more important than knowledge. For knowledge is limited, whereas imagination embraces the entire world.'

- Albert Einstein

View the model of the tobacco mosaic virus from the 1958 Brussels World's Fair

After she finished analyzing her X-ray diffraction data on DNA fibers, Rosalind Franklin explored plant virus structures. For her work on the TMV, she was invited to build this 5-foot model, modified from earlier versions made of ping pong balls and bicycle handlebar grips.

Scientific progress works toward absolute truth, but can never reach it

Through the acquisition of scientific knowledge, scientists construct explanations of the world, which are rigorously tested and verified until they narrow down to a leading theory of the natural world. However, because of how science works, these ideas will never become factual, as they must always remain open to be iteratively revision based on new data.

X-rays earned the very first Nobel Prize in physics for revealing hidden worlds

In 1895, Wilhelm Conrad Röntgen discovered X-rays, which could pass through solid objects and make unseen structures visible. Today’s X-ray tools continue to advance science and medicine, including capturing real-time images of proteins.

Learn the history of food science breakthroughs from the 20th century

Long after humans developed the means to produce sufficient food to feed civilizations, scientific research focused on a wide variety of objectives, such as developing methods to preserve food quality (accomplished via frozen food), speeding up cooking (leading to the microwave), and lowering the cost of sweetening food, which high fructose corn syrup provides.

Inside the community movement behind DIY synthetic biology

Margaret Talbot spotlights the rise of DIY biology in community labs, where amateur scientists—often outside formal institutions—create everything from insulin to prosthetic prototypes. These grassroots biohackers challenge traditional science by pursuing open, accessible innovation, raising questions about credibility, ethical oversight, and acceptance by mainstream researchers.

View an historical mural depicting the NSF's impact across seven decades

From 1950 to 2020, the National Science Foundation supported discovery-based, exploratory research that led to numerous breakthroughs, including the development of supercomputing centers, 3D printing technologies, biometric identification systems, an understanding of vector-borne illnesses, a DNA amplification technique, mobile meteorology units, and scientific education and literacy programming.

According to Bill Nye, science is under threat from an erosion in critical thinking

He states that conducting research online cannot replace consulting with scientific experts who have spent their entire lives intimately studying a field. The former science education show host argues that deepening cynicism towards scientific institutions has been fueled by leaders embracing debunked and unsupported claims.

The simple grandeur of atomic theory

Is the universe made up of a continuous substance, or a finite amount of tiny, indivisible atoms? The atomic hypothesis, largely vindicated in the 20th century, was forgotten for nearly 2,000 years after first being formulated by the Greek philosopher Democritus. Learn more about the theory and its implications for science and human life with this reflective essay.

'A life is not important except in the impact it has on other lives.'

- Jackie Robinson, the first Black MLB player (1919-1972)

Rudolph Fisher was an incisive writer—and a practicing physician

Fisher was one of the luminaries Langston Hughes cited in "The Negro Artist and the Racial Mountain" and was known as an impressive polymath, writing stories, acting in plays, and practicing medicine. In this deep dive, science writer Harriet A. Washington explores why he's often neglected in modern narratives about the Harlem Renaissance.

The origin of the National Science Foundation and why World War II led to its founding

Before World War II, research institutions were funded by endowments or private companies whose priorities stifled the curiosity-driven science that fueled significant breakthroughs and innovation. The NSF was established in 1950 to promote independent scientific progress through basic research, which is focused on knowledge acquisition rather than commercial applications, conducted at national colleges and universities.

A quote from Sally Ride

“Three Secrets to Success: Be willing to learn new things. Be able to assimilate new information quickly. Be able to get along with and work with other people.”

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

'Many of life's failures are people who did not realize how close they were to success when they gave up.'

- Inventor Thomas Edison (1847 - 1931)

Marie Curie's daughter Irene discovered artificial radioactivity

The discovery continued the family's Nobel legacy by winning the Nobel Prize in Chemistry in 1935 alongside her husband, Frederic Joliot. Their work laid the foundation for the use of radioisotopes in medicine, agriculture, and energy production.