A top Alzheimer's researcher was accused of faking results

Recent evidence raises the question of whether conventional wisdom about amyloid plaques and their connection to Alzheimer's is wrong.

Scientists are reevaluating the causes of Alzheimer's beyond the amyloid hypothesis after numerous experimental drugs designed to target that theory have failed.

The scandal that rocked stem cell research

In 2014, a Japanese research group published a paper suggesting ordinary cells could be reverted to pluripotent stem cells by subjecting them to external stressors. The results generated interest but could never be replicated. The lead researcher was accused of fraud, and the group’s supervisor committed suicide.

"Plaques" and "tangles" are top potential causes of Alzheimer's—but questions remain

The exact causes of Alzheimer's—and how to treat it—continue to be the subject of intense research. Two leading factors are amyloid beta plaques and tau protein tangles, which effectively pile up in the brain and interfere with neurons and cause cell death, which manifests as memory loss and other symptoms.

Researchers are exploring neural links between Alzheimer's and autism

Recent DNA sequencing and molecular biology studies suggest that similarities in genes, neural circuitry and patterns of disease warrant further exploration to potentially better understand both conditions and how to treat them. (Some users may encounter a paywall.)

Researchers use the brain's ability to edit memories to explore memory deletion

Scientists have successfully implanted false memories in mice after studying how the editing process works in the brain. Beyond potentially deleting memories in those with PTSD, upcoming research may allow clinicians to forecast the onset of neurodegenerative diseases.

More than 200 drug trials for Alzheimer's have failed or been abandoned since 2010, but two anti-amyloid infusion medications have netted FDA approval in recent years.

There are two FDA-approved blood tests that may detect early Alzheimer's disease.

Read the original 1907 paper on the first known Alzheimer's patient, which was identified by Dr. Alois Alzheimer.

Explore this 1440 Original video offering a primer on Alzheimer's disease and what's known about its incidence, causes, and more.

The first identification of Alzheimer's was made in 1906.

Alzheimer's can cause significant brain shrinkage in the affected brain regions, including the hippocampus.

A pediatric journal ran 138 fictional case studies, and 61 were cited as real stories

The Canadian journal Paediatrics & Child Health issued corrections to 138 case studies published since 2000, acknowledging the cases were entirely fictional—a practice intended to protect patient privacy that was never disclosed to readers. At least 61 of the fabricated reports were cited as fact in other peer-reviewed journals a combined 218 times, including a 2006 Lancet article alleging an infant died from opioid-laced breast milk.

Deepfakes came to prominence in the form of nonconsensual pornography

The explosion of deepfakes depicting renowned people in both ridiculous and compromising videos has provoked widespread fears they will undermine public trust in authoritative knowledge. However, some scholars argue that real videos will always be distinguishable from deepfakes via the video-sharer's testimony and a broader social context.

Alzheimer's brain changes may begin years before symptoms appear.

Does our fear of Alzheimer's create stigma around its treatment?

Surveys suggest our fear of Alzheimer's as a disease outranks that of heart disease and cancer. This piece argues our fear of aging and the slipping away of our mental capacities make it more difficult to treat Alzheimer's compassionately.

Read the main paper criticizing the concept of blue zones, which argues recordkeeping errors, pension fraud, and natural disasters likely explain the high numbers of purported healthy centenarians in certain locations.

Supplement sales soared during the pandemic, alongside growing distrust of the health establishment, amplifying a trend that endures—even when some of the products don't even work.

Early-onset Alzheimer's can appear as early as age 30, but estimates of its prevalence remain uncertain.

One man used an AI band called the Velvet Sundown to conduct what he called an elaborate social experiment.

Medical experts warn that completing genetic testing for Alzheimer's can be fraught, in part because there's a shortage of genetic counselors to help navigate the findings and their potential implications.

How Alzheimer's caregivers get pulled into their loved one's reality

Caregivers, most often children and spouses, do not just witness a family member's cognitive decline—they also often become drawn into it, navigating a world in which the typical rules of time, order, or logical continuity may not apply.

Malicious use of deepfakes can be found in scams, misinformation, and disinformation

Artificial neural networks can identify an individual's physical characteristics when provided with training data, such as real footage of the person speaking. Graphics techniques overlay these with matching characteristics from another real or generated person to create novel footage of things that have never taken place in reality.

Genetic blood test offers an estimated clock on when Alzheimer's symptoms may appear

The 2026 research finding from researchers at Washington University School of Medicine in St. Louis—if validated in broader populations—suggests that an already available blood test could estimate when Alzheimer's symptoms may begin within a margin of several years. The test detects a protein called p-tau217 found in blood plasma and the researchers incorporated the findings from that blood test into a statistical model to come up with the symptom timeline predictions.

Did a Smithsonian anthropologist steal people's brains?

This comic examines "racial brain collection" of Ales Hrdlicka, the Smithsonian's head of physical anthropology during the early 1900s. Hrdlicka was a white supremacist who sought physical evidence for his theories on anatomical differences between...

Retired professional soccer players are showing signs of potential neurological impacts in midlife, according to a study presented at the July 2026 Alzheimer's Association International Conference in London.

Investigation finds 'influencer' dietitians paid to promote sugar, supplements on social media

A joint investigation by The Examiner and The Washington Post found that food, beverage, and supplement corporations and groups have paid registered dietitians on social media to promote content that goes against decades of scientific evidence on...

Six of history's most unethical human experiments, from deliberate flu exposure to withholding syphilis treatment

Some of the progress made in mental health treatment, vaccines, blood transfusions, and more came about before the advent of consent and ethics committees, resulting in serious physical and psychological harm that participants in studies were not even anticipating.

Five to ten percent of Alzheimer's cases are early-onset

Early-onset Alzheimer’s typically emerges around 40 to 50 years of age, with devastating effects. This video follows Brian, diagnosed with the disease at age 54, as he travels the country as an advocate for research and discusses the progressive mental fog of Alzheimer’s.

Poor sleep increases the risk of developing Alzheimer's, and a main reason appears to be that the brain disposes of toxic protein buildup during high-quality sleep.

Visualize the difference between a healthy brain and one with Alzheimer's.

American medical organizations rescind recognition of diagnosis cited in police custody deaths

American medical organizations have rescinded their recognition of a syndrome whose theory stemmed from discredited research. This article explores the history and implications of "excited delirium syndrome," a medical condition that can reportedly...

A physician with a rare and deadly disease saved his own life by identifying an existing medication that he repurposed for his condition, and now he's using AI to try to do the same for other patients.

True crime fans can derail lives with misguided accusations

In the wake of four stabbing deaths at the University of Idaho in November 2023, online sleuths, without any supporting evidence, were quick to point accusatory fingers at potential perpetrators. Poring over news reports, social media pages, and internet interactions can reveal viable information that can help solve crimes. Such (sometimes monetizable) behavior can also easily give rise to rumors and threats while impeding official investigations.(Some readers may experience a paywall.)

The ease of deepfakes creation may soon overwhelm our sense of digital truth

Shortly after the public release of related technology in 2017, some experts saw the technical limitations of deepfakes as preventing them from becoming widespread tools of disinformation. Since then, the neural networks behind diffusion models and generative AI have eliminated the barriers to creating convincing synthetic media for propaganda.

The spread of fraudulent stem cell treatments

All the coverage of research into promising (but often unproven) medical treatments involving stem cells has created conditions allowing some people to engage in activities regulators describe as scams. As this news article explains, attorneys general in at least seven states have taken legal action against businesses that promised (costly) stem cell treatments but allegedly engaged in fraud.

How Alzheimer's disease affected one family as symptoms progressed

News program 60 Minutes interviewed a couple navigating aging and Alzheimer's over a 10-year period to illustrate the effects of the disease on their lives.

Two festival-goers were hospitalized after receiving trendy peptide injections, raising safety questions that may extend beyond the event.

Deepfake videos impersonating real doctors are spreading false medical advice

More than 100 videos, found primarily on Instagram and TikTok in August 2025, promoted products related to beauty, wellness and weight loss. While TikTok removed 94% of content violating its policies on AI-generated content, these deepfakes were watched and shared before removal, undermining public trust in medicine.

Most self-reported claims of exceptional longevity are exaggerated, but read how demographers verify age claims and why some of the original blue zone demographers say blue zone regions are real and worth studying.

Watson's book was described as misleading when detailing Franklin's role in DNA

Despite working together to win the Nobel Prize for their discovery of the structure of DNA, Francis Crick and Maurice Wilkins objected to the publication of James Watson's account of DNA's discovery. Those involved describe how he villainized Rosalind Franklin and downplayed her work.

Some Nobel laureates have expressed beliefs in pseudoscience after winning

Examples of the phenomenon, known as Nobelitis or Nobel disease, include promoting psychic research, harmful practices like eugenics, and seeing talking raccoons. Increased external pressures after a win and a greater spotlight may contribute to developing or exposing these beliefs.

Minorities are largely underrepresented in medical research, which compromises our understanding of how conditions and treatments may affect various populations, but recent efforts, like the African Ancestry Neuroscience Research Initiative and new genome research studies, are seeking to close that gap.

A funeral director lied and claimed he discovered a centuries-old Roman brooch

An amateur metal detectorist knowingly deceived thousands into believing he found an 1,800-year-old horse figurine. He received payment for the artifact to be featured in a museum, but he later admitted he bought the brooch online and planted it.

33 images that became central to huge scandals

A 2024 cheating scandal cast doubt on the industry

In 2024, National Fantasy Football Championship, a fantasy league with big payouts, fired one of its employees for manipulating data. The episode cast doubt on the relatively unregulated industry, despite the league coming down hard on the nefarious worker.

See how faces on magazine covers have changed over time

This piece examined an archive of Time magazine containing 3,389 issues ranging from 1923 to 2014, focusing on 327,322 faces from the archive. Read what the researchers learned.

In 2008, one writer demonstrated the fickle nature of wine reviews

Robin Goldstein submitted a fake restaurant to the well-respected Wine Spectator for a competition. He created a website for the fake Milan-based business, complete with a menu of wines the magazine itself had disparaged. That didn't stop Wine Spectator from naming Goldstein's ruse among that year's winners.

How Congressional oversight can override confidentiality in the NSF's proposal review process

In 2014, to investigate claims that the NSF was funding wasteful research rather than proposals that served national interests, confidential grant files were provided and reviewed by members of the House Science Committee. The actions, led by Lamar Smith (R-TX), were denounced by the scientific research community. (Some readers may experience a paywall.)

Deepfakes images can be identified by visual elements that do not match real-world phenomena, including asymmetric eyes or earrings, surreal backgrounds, and indecipherable background text.