Bacteria use chemical signals to communicate and coordinate with one another

Bacteria rapidly evolve (and share) new defenses against drugs they encounter

Unlike humans, bacteria rapidly make genetic changes in response to their environment, including creating defense against antibiotics. Furthermore, these defenses are passed on to their future generations and can even be shared with neighboring bacteria through horizontal gene transfer.

Single-cell organisms have circadian clocks that direct daily biochemical routines

Cyanobacteria, a type of light-sensitive bacteria, use this clock to signal when to alternate between making organic compounds through photosynthesis and when to convert atmospheric nitrogen into usable ammonia. Upregulating photosynthetic machinery before dawn helps ensure efficient photosynthesis.

Superbugs evolve defenses against medication, then share them with neighbors

One reason antibiotic resistance spreads so quickly is that bacteria have multiple mechanisms allowing them to share genetic material. This short video offers a concise explanation for each of these mechanisms, and animation that helps viewers understand how antimicrobial resistance can quickly spread from one organism to another.

How bitter taste receptors help guard against infection

Receptors for "bitter" tastes evolved to detect potentially harmful plant chemicals, such as nicotine. The receptors also trigger bacteria-fighting responses, including waving hairlike projections to bat away bacteria, ordering the release of bacteria-killing nitric oxide, and calling for antimicrobial protein reinforcements.

Bacteria in our intestine influence the brain via the gut-brain axis.

As immobile animals, corals and the organisms that live on them have evolved a suite of chemical compounds to prevent disease and ward off predators they cannot outrun.

Bacteriophages—viruses that infect bacteria before multiplying within them—exist on Earth in numbers greater than all other living organisms combined.

Trillions of bacteria, viruses, fungi, protists, and archaea live in our guts, producing a wide range of molecules, hormones, and more—underscoring the immune system's pivotal role in the microbiota-gut-brain axis.

In 2026, University of Cambridge researchers reported that a group of gut bacteria called CAG-170 may be a key marker of good health, occurring far more often in healthy individuals and less commonly in people with chronic diseases.

CRISPR-Cas systems act as genetic memory banks for defending bacterial cells

When viruses called phages inject DNA into bacteria, some bacterial species store bits of this DNA in their own genomes. This allows them to recognize and destroy the same virus if it attacks again.

Recombinant DNA technology turns microorganisms into protein factories

Genes for molecules such as insulin can be inserted into loops of bacterial DNA called plasmids and reinserted into bacteria. Once placed in fermentation tanks, these bacteria use the gene to produce these molecules, which are then harvested and purified for eventual use.

Bacteria have been genetically engineered to bioluminesce when wine has spoiled

Developed by researchers at Hebrew University, the method involves the firefly enzyme luciferase, which emits light from within bacteria expressing when they are in the presence of acetic acid vapors produced by wine. The process provides affordable, on-site, real-time monitoring of fermentation quality.

Researchers generally group gut bacteria into six different categories, with varying amounts of these microbes residing in different parts of the digestive tract.

Corynebacterium species are particularly responsible for our funky smell

Myriad bacteria contribute to our body odor, but research suggests that Corynebacterium species are strongly associated with the bad smells emanating from adults. Staphylococcus and Cutibacterium genera may also play leading roles.

Explore how cells respond to signals from their environment

In "Dropping Signals," users can drag stimuli, such as hormones and light, into various cellular environments to observe cellular responses. These include changing their shape, enabling the transport of chemicals into or out of the cell via the cell membrane, or dividing to compensate for surrounding damaged cells.

A dog's nose can be up to 100,000 times more sensitive than a human's, and each possesses a secondary organ for smelling, which helps learn about other dogs when they sniff each other's butts.

An estimated 1% of DNA mutations in bacteria can produce more dangerous strains

Researchers have developed a technique to monitor these mutations in real time. Using this technology, scientists found that mutations occur at a steady rate, with 1% leading to potentially deadly changes.

Solutions of bioluminescent bacteria can create FOMO-inducing living art

A 2002 exhibition at Montana State University-Bozeman placed the bacteria onto petri dishes that served as macroscopic pixels to create images. Once the bacteria finished eating all the food in the sealed dishes, the light slowly faded away, ending the exhibit.

Bioluminescent organisms produce their own light through chemical reactions involving unstable, energetic molecules, while biofluorescent organisms almost immediately re-emit light shone on them, but at a different wavelength.

The term 'symbiosis' was coined during the study of lichens—composite organisms in which algae or cyanobacteria partner with a fungus, alongside bacteria.

View illustrations of bioluminescent functions in marine organisms

Bioluminescence can startle predators, camouflage, lure prey, confuse rivals, or facilitate mate recognition. One tactic—the burglar alarm—involves an organism releasing light to attract a larger predator to its attacker as a means of defense.

Microbes are essential to creating the many varieties of cheese, influencing texture and taste

Microbes break down proteins and fats and produce compounds with distinct tastes. These microbes can include bacteria (like the one used to give Swiss its trademark holes), molds (like the ones that give blue cheese its distinctive veining), and countless other tiny organisms.

Bacteria helped scientists realize that DNA was the hereditary molecule, not proteins

Until the mid-1900s, most scientists believed genes were made of proteins, which were known to act as enzymes, hormones, and other chemicals that mediated an organism's traits. The Avery-MacLeod-McCarty and that benign bacteria could be made lethal, where the inherited factor that caused bacterial transformation contained DNA.

Cells modify their internal spacing to improve biochemical reaction efficiencies

Studies involving microscopy and genetic engineering tools in yeast and human cells show ribosomes act as crowding agents—much like packing peanuts—and their concentrations are actively tuned to alter the rate of cellular functions. However, these concentrations and cell crowding levels vary across different tissues and cell types.

Why bacterial bioremediation may help counter the negative effects of past chemical solutions

Molecules such as DDT, a synthetic insecticide, and PFAS—"forever" chemicals used to make products resistant to heat, water, and grease—have historically been used across various industries but are now known to be harmful. Microbes that can convert some of these substances into nontoxic products, such as water and carbon dioxide, have already been identified, with ongoing research to find others.

Some female fireflies mimic the signals of other species to lure in and eat them

The genus Photuris does not produce its own defensive pheromones to ward off predators, so it has developed mimicry to attract males of firefly species that do. Unsuspecting males are consumed after these chemicals—lucibufagins—are extracted.

Instead of consuming water and carbon dioxide to produce oxygen and sugar, anoxygenic photosynthesis involves alternative reactants and products.

Glowing chemicals allow scientists to read DNA like a barcode

The process of determining the order of nitrogenous bases in DNA involves first cutting the DNA into fragments, which are duplicated multiple times using bacteria. Fluorescently labeled terminator bases are added to fragments, which are sorted by length and read via laser to reconstruct the sequence.

There are up to 100 trillion microbes in the gut, and maintaining the relative balance in this ecosystem is important for our health.

Research on bacterial cultures used in yogurt production led to CRISPR's discovery

Scientists learned it was a microbial immune system that could be repurposed to protect dairy cultures from viruses. Today, nearly all yogurt is made with CRISPRized bacteria, as are genetically modified crops like herbicide-resistant corn, wheat, and soy.

Bioluminescence provides organisms with a method of hunting, defense, or mating

Unlike glow sticks, bioluminescent reactions use renewable resources like oxygen and ATP. This ability allows fireflies to mate and deter predators, anglerfish to confuse and attract prey, and deep-sea shrimp to defend themselves by vomiting glowing slush.

Learn how environmental conditions are optimized to increase bioremediation efficacy

Through biostimulation, Indigenous microbes are provided with moisture, nutrients, or oxygen to prevent their death and ensure optimal progression of their biochemical reactions. Bioaugmentation can introduce new microbial cultures to target specific compounds not natively found in the environment, while landfarming can spread or aerate contaminated soil to improve access to contaminants.

Gut bacteria are evolving and can acquire as many as 100 new genes per year, on average.

Our sense of smell affects what foods taste like and how we perceive it

Scent stimulates our olfactory sensor neurons high in the nasal cavity, and the brain attaches labels to those scents. But when we eat, chemicals from the foods travel from our mouths and throat to those neurons. We have roughly 400 odor receptors, and they can be used to decipher more than 10,000 different odors (or more than one trillion by some calculations), including the nuances of different foods.

The flavor of food can be enhanced by combining chemicals known to trigger umami taste receptors with nucleotides—building blocks of DNA and RNA—triggering an effect called umami synergy.

These cells 'taste' danger, trigger immune responses

Taste receptor-coated tuft cells are found throughout the body, where they communicate with and take part in a growing list of biological processes. In the intestines, these taste receptor-studded cells can sense byproducts of parasite metabolisms. This causes the taste receptors to release chemicals that alert the immune system, order nearby goblet cells to produce mucus, and trigger muscle contractions in attempts to launch the parasites from the intestines.

Neurons send signals through electrical impulses and chemical messengers

By converting electrical signals into chemical messages at synapses, neurons allow information to travel throughout the nervous system. With repeated use, synapses grow stronger, enhancing the associations between neurons.

Gut microbiome experiments involving transfers of gut microbes from depressed people to rodents indicate that the rodents may then display depression-like symptoms.

The research that led to sour

Scientists are trying to figure out if there are unique receptors that respond to the molecules that make up flavors we associate with calcium, blood, batteries, and other items that often escape dinner menus. Taste researcher Dr. Danielle Reed says the minimum evidence for a taste category typically involves identifying dedicated receptors and then removing them to show the taste vanishes.

The adaptations of metallophiles and how they can be harnessed for bioremediation

These extremophiles have adapted to biomes with very high concentrations of metals and toxic chemicals by developing mechanisms to isolate these substances within cellular compartments and break them down into less harmful forms with specialized proteins. They have the potential to support the decontamination of metal-rich wastewater and soil, as well as the extraction of rare-earth metals.

View the industrial applications of extremozymes, from food safety to antibiotic production

Extremophiles possess unique enzymes and organic molecules that have enabled them to adapt to and thrive in otherwise lethal environments. Because these conditions resemble those found in various areas of manufacturing and production plants, these organisms and their macromolecules can optimize industrial processes where conventional catalysts would lose their ability to speed up reactions.

Scientists can tag distinct proteins with fluorescent probes that emit different colors, allowing them to visualize multiple biochemical processes simultaneously.

An overview of extremophiles and the biochemical adaptations employed by various types

These organisms thrive in environments that would normally be inhospitable to most living things by using molecules that help counter deadly environmental factors. These include antifreeze-like proteins that prevent psychrophiles from freezing and rupturing in polar regions, and osmoprotectants that prevent some extremophiles from losing water to salty environments.

'Gram-negative' bacteria: Bugs with extra defenses along their cell walls

The term 'Gram-negative' bacteria refers to bugs which react a certain way under a Gram stain test. These bacteria are harder to kill due to their double-layer cell walls with a thin peptidoglycan layer in between. This structure makes the delivery of drugs into the bacterial cell substantially more difficult.

Breaking down the challenges of alkaline environments and how extremophiles survive them

These areas are far less acidic than the interiors of most organisms' cells, and this imbalance draws protons that are needed for various metabolic processes, including energy production, out of cells. To counter these effects, some alkaliphiles have developed stronger proton regulation across their cellular membranes and proteins that drive these processes with greater stability amid such acidity imbalances.

How the five senses share information with each other

The human body depends on information from the five sensory organs—the eyes, ears, nose, tongue, and skin—to react to the world around it. Each of these organs, in its own way, relies on complex circuitry to send signals back to the central nervous system.

Fear (and stress) can be contagious via pheromones secreted by the body

While seeing someone else in a panicked state may induce a stress response, researchers have found stress can be literally contagious—chemicals contained in sweat and other secretions can trigger stress hormone release in others. Theories suggest this feature is an evolutionary adaptation to protect groups from danger.

Scientific applications of bubbles include logic gates, laser production, and medical imaging

Microbubbles of nonreactive gas can be administered to improve the reflection of sound waves and the resulting imaging during an ultrasound. Bouncing light waves within a bubble can stimulate emission of light from a trapped chemical, just as occurs within a laser, and bubbles can act as valves that control the flow and reaction rates in microfluidic systems.

Sweat doesn't smell, but bacteria multiply in moist environments—and cause an odor

Body odor is associated with sweat, but odor actually arises from the bacteria that multiply in moist environments on your skin. Hormones, medications, food, and body hair can all affect body odor.

Evidence suggests the first cells on Earth were bacteria

About 4 billion years ago, these single-celled organisms harvested carbon dioxide and sunlight to produce their own food and oxygen, setting the stage for the evolution of oxygen-breathing life forms. Archaeabacteria, which thrive on inorganic molecules in extreme habitats on Earth today, were also among the earliest organisms.