In 1971, a $35 ferret helped clean the Fermi National Accelerator Laboratory

In 1933, the influenza virus was first identified through 'ferret flu' experiments, which proved that the disease was viral—not bacterial.

The Large Hadron Collider repurposed an excavation tunnel built for the Large Electron-Positron Collider, which was used until 2000 and whose construction involved the largest civil engineering project in Europe before the Channel Tunnel.

Before 1932, when particle accelerators were first used for nuclear research, scientists relied on naturally radioactive substances to advance their understanding of the atomic nucleus.

Fermilab's ICARUS experiment is searching for hypothetical sterile neutrinos

Neutrinos are a group of three chargeless, lightweight particles that can transform into one another via a quantum mechanical phenomenon called neutrino oscillations. The rate of these oscillations can be determined by measuring the amount of each type at different distances, where data inconsistencies would suggest the existence of new physics.

Learn about five of the largest particle accelerators on Earth, which, as of 2026, are led by the Large Hadron Collider at the European Organization for Nuclear Research.

Particle accelerators have been used to reveal detailed ant anatomy

Using a synchrotron facility at the Karlsruhe Institute of Technology in Germany, a pair of X-ray beams swept across about 2,200 ant specimens to create over 200 terabytes of projection images from multiple angles. The images were compiled into micrometer-resolution 3D reconstructions of 792 species, which are freely accessible on the Antscan platform.

At the CERN Control Center, where the Large Hadron Collider and connected accelerators are managed, champagne bottles from parties commemorating major milestones, such as the first collisions or a new record energy, are collected.

At CERN's Antimatter Factory, researchers create and guide antiprotons and antielectrons together to form antihydrogen, and all these antiparticles are analyzed to help scientists study the behavior of antimatter.

Each year, the Large Hadron Collider undergoes a winter shutdown—when electricity costs are highest—and bringing it back online requires weeks of tests, including some involving high-energy particles from outer space.

Since 2026, the Large Hadron Collider has provided heat to thousands of French homes and businesses through a system that harnesses hot water from the accelerator's cooling circuits.

A beam of neutrinos can be created by firing a beam of high-energy protons at a target to produce unstable particles that decay into neutrinos.

Although built from 1996 to 2008, the Large Hadron Collider relies on accelerators built starting in 1954 to help bring protons to 99.9999991% the speed of light—about 2.73 million football fields per second.

Italian physicist Enrico Fermi (1901–1954) on the Standard Model

"If I could remember the name of all these particles, I'd be a botanist."

As of 2023, the world's smallest particle accelerator is smaller than a penny

The prototype is an example of a photonic accelerator, which utilizes tiny lasers to accelerate electrons rather than relying on oscillating electromagnetic fields to move them. It can deliver about 1 electron per second with energies equivalent to those found in cathode-ray tube televisions.

CERN—the European Organization for Nuclear Research—is the world's largest particle physics laboratory, with the Large Hadron Collider serving as its largest tool.

The first circular particle accelerator was narrower than the average cereal bowl

The 1939 Nobel Prize in physics was awarded to Ernest Lawrence for inventing the cyclotron. By comparison, the Large Hadron Collider is 5 miles in diameter and is the largest cryogenic system in the world, cooling its electromagnets to temperatures colder than those found in outer space.

Synchrotron radiation has revealed the fur color of creatures millions of years old

When electrons are accelerated in the loop, they produce intense X-rays that can reveal properties of a sample struck by them, just as X-rays can be used to show bone structure in humans. Studying the reflected light from fossils can uncover the presence of known pigmentation compounds.

At the Large Hadron Collider, protons are accelerated so close to the speed of light that they would lag behind a laser by just 10 feet after 14 minutes of travel.

Particle accelerators propel matter toward small targets at high speed

Devices like cathode-ray tube televisions were once basic particle accelerators, but modern ones, such as the Large Hadron Collider, use massive magnetic fields and circular tunnels to achieve energies high enough to recreate the conditions just after the big bang.

The Louvre in Paris has its own particle accelerator for art analysis

The Accélérateur Grand Louvre d'analyse élémentaire serves as a noninvasive tool for identifying and quantifying trace elements present in artworks by analyzing how particles backscatter off targets. This information can help detect forgeries and determine a piece's provenance. (Some readers may experience a paywall.)

Play an incremental game that teaches the history of particle physics

Developed during the CERN Summer Student Webfest 2014, this game tasks you with building the reputation of your particle accelerator as you discover particles and hire staff to collect data. A historical breakdown accompanies each discovery, allowing you to recreate the timeline of the field.

Particle accelerators detect subatomic particles using millions of sensors

Calorimeters measure the energy of particles. Tracking devices can measure momentum and charge from the trajectory of particles, which is determined by recording tiny electrical signals. Time-of-flight detectors provide particle velocities directly and particle mass indirectly, giving physicists a suite of properties to compare with those of known matter.

The Large Hadron Collider is the world's largest cryogenic system, which uses 10,000 metric tons of liquid nitrogen and 120 metric tons of helium to cool 36,000 metric tons of magnets to temperatures colder than outer space.

The NSF funded the design and construction of LIGO by MIT and Caltech

The 1992 Cooperative Agreement between the National Science Foundation and both research institutions came twelve years after funding 1.5-meter (4.9-foot) and 40-meter (131-foot) prototypes. With a 1992 budget of $395M, LIGO was once one of the largest NSF-funded projects in history

Through 2038, the Large Hadron Collider research program is expected to generate societal benefits of €25.6B, or €3.3B more than operating costs and investments.

Unlike the other major detectors at the Large Hadron Collider, the Compact Muon Solenoid—one of two general-purpose detectors—was built above ground and then lowered underground in sections for reassembly.

More than 97% of the world's particle accelerators are used for commercial purposes

Only a few hundred of the over 30,000 particle accelerators worldwide are used for research. Most are involved in medical imaging and treatment, food sterilization, semiconductor processing, cargo screening, and radioisotope production. They're also used to modify the properties of polymers.

Scientists can create movies of atomic and molecular phenomena using X-ray free-electron lasers, in which images are produced by matter being struck by high-intensity light created by accelerating electrons.

In an X-ray free-electron laser, electromagnetic fields are used to accelerate and move electrons in wiggling patterns, causing them to emit synchronized, high-energy X-rays. This resulting light beam can strike targets up to 120 times per second to create movies of changing molecular structures and phenomena.

A particle accelerator allowed researchers to noninvasively examine a mummy

The mummy hailed from the Faiyum oasis, where Egyptian and Roman cultures intersected, and was analyzed using the Advanced Photon Source at Argonne National Laboratory. The device used high-energy X-rays to probe the material composition of numerous objects embedded deep inside the mummy without damaging its remains.

Watch an animated visualization of how the Large Hadron Collider works, including how particles are accelerated through a series of machines and how collision data is collected and distributed worldwide.

A 36-year-old Russian physicist survived a particle accelerator beam to the head

Several safety mechanisms failed during Anatoli Bugorski's inspection of malfunctioning equipment at the U-70 synchrotron, the Soviet Union's largest particle accelerator. Despite receiving as much as 600 times the lethal dose of radiation to the brain, he has shown no intellectual damage and worked until the age of 77.

Explore the components of the linear particle accelerator at Los Alamos

Located at the site of bomb design and development for the Manhattan Project, LANSCE features an injector system for hydrogen ions, a series of tanks with alternating electric fields for proton acceleration, and an isotope production facility that creates radioisotopes for medical treatments.

Take a 360-degree tour of ATLAS, one of two general-purpose detectors at the Large Hadron Collider and the largest particle detector by volume ever built. (VR device-compatible)

In 2026, researchers successfully transported antimatter in a truck using a portable trap that employed electromagnetic fields to hold 92 antiprotons.

Learn how to build your own cloud chamber to detect cosmic rays—particles from space that move near the speed of light—at home.

Mixed reality technology helped make repairs to a quantum physics facility in space

In 2021, astronaut Megan McArthur used a HoloLens to work alongside Earth-based engineers and make hardware replacements to the International Space Station's Cold Atom Lab, the first quantum science facility in Earth orbit. The facility cools atoms to near absolute zero to perform quantum chemistry experiments in a microgravity environment.

The High Luminosity Large Hadron Collider will provide a tenfold increase in particle collisions compared with the initial LHC infrastructure by increasing the number of ions in collision bundles and by concentrating the ion beams.

On average, the Large Hadron Collider uses 1.3 terawatt-hours of electricity annually—equivalent to about 124,000 US homes—generated by a French substation.

At the Large Hadron Collider, scientists have transformed lead into gold—a process known as chrysopoeia, which alchemists sought for centuries.

Particle detection has evolved from cloud and bubble chambers to digital 3D displays

As invisible particles passed through cloud and bubble chambers, they disrupted supersaturated vapor and superheated liquid, respectively, creating trails that served as proxies for cosmic rays. The transition from photographed events to digital sensors enhanced data collection and accuracy.

IBM Quantum’s dilution refrigerators keep quantum processors colder than space

In IBM’s quantum lab, quantum processors are kept at a temperature of 15 millikelvin using dilution refrigerators. These refrigerators use nested thermal layers, cryogens like liquid nitrogen and helium, and powerful compressors to maintain the ultra-cold temperatures required for qubit stability and performance.

The most common type of particle accelerator is a linear electron accelerator, which fires particles in a straight line, making them useful for the intense, targeted beams needed in cancer treatment.

What rodent cars can tell us about human joy

Neuroscientist Kelly Lambert and her colleagues taught rats to drive in a mini car. She writes her findings from this unconventional experiment, sharing that positive and fun experiences can sculpt the brain just as powerfully as stressful ones. Click to learn more about how the apparent joy of these rodents seemed to enhance their neuroplasticity.

Space trash could be cleaned up using a giant inflatable bag

California-based TransAstra has developed and tested a device called Capture Bag, intended to catch anything from small rocks to house-sized boulders. The company claims its system could also be adapted for asteroid capture and mining.

Efforts to find Majorana particles may finally lead to reliable quantum computers

Though the particle—which is its own antiparticle—remains theoretical, scientists from Microsoft to Google continue developing systems to mimic this property towards building error-resistant quantum computers. Scientists at UCSB have been attempting to get the particle using just pencil lead and Scotch tape.

A financial analysis of space trash cleanup strategies identified long-term benefits

Despite significant initial costs, a NASA report found that removing small debris would provide savings from preventing mission-ending damage, which would offset expenses within a decade. Financial benefits would also come from using less fuel for maneuvers to avoid collisions with debris.

Cyclotrons move particles in spiral paths of increasing radius

After particles are injected into the center of the device, an alternating electric field and a constant magnetic field energize the particles as they spiral outward toward a target. Cyclotrons are common in hospitals that perform molecular imaging, which relies on radioactive components that decay within hours.

Watch how the machine at the heart of NASA's Cold Atom Lab produces atoms near absolute zero—the coldest theoretical temperature in the universe—for experiments involving quantum phenomena.

The Curies developed a way to measure radioactivity in an old medical dissecting room

Despite lacking proper laboratory conditions, Marie and Pierre built an ionization chamber and a piezoelectric quartz electrometer to measure the amount of charged particles released by radiation, with a sensitivity of ten-trillionth of an ampere. Substances with different emission rates indicated different elements.

Dilution fridges create the colder-than-space environments needed for quantum computers by successively lowering temperatures across layers plated with gold, which reduces heat transfer via radiation and gives them a chandelier-like appearance.