A weed from the mustard family facilitated the molecular era of botany

While humans have been genetically modifying plants for millennia by selectively breeding organisms with certain traits, gene-editing tools like CRISPR have further enhanced plants, conferring resistance to drought, pests, and diseases.

Genetic engineering has accelerated millennia of altering various crops' genes

Although farmers have long cross-bred crops to obtain plants with specific colors, sizes, and other characteristics, these processes took significant time. Today, genetic modification in agriculture involves scientists altering an organism's DNA for various purposes, including enhancing pathogen resistance, removing allergens, and delaying spoilage.

Green algae have lived on Earth for about 1 billion years, roughly twice as long as the first plants.

What is genetics?

What is a genome, and how are traits passed from generation to generation? Learn how pea plants helped launch the study of genetics and how the field of genetics research has evolved over time.

Advances in agriculture are being powered by CRISPR to boost carbon capture

Researchers are using CRISPR to test thousands of plant gene edits, aiming to speed up breeding and maximize carbon retention in soil. By engineering drought tolerance, they also aim to increase crop yields and expand the environments where crops can grow.

How flowering plants took over the world

Flowering plants are relatively young in the evolutionary scheme of things, only arriving after the dinosaurs had already been wiped out. Their evolution has long puzzled scientists, but recent research indicates their success is due to smaller,...

Flowers have been around for 123 million years

Fossilized pollen grains reveal that flowering plants have existed on Earth for 123 million years, and their emergence considerably enriched the planet's biological diversity. They may also have been more widespread than initially thought—prior assumptions were that the eudicots, the first flowering plants, appeared 121 million years ago.

See a timeline of landmark discoveries in the field of genetics to gain a better understanding of more than a century of advances.

The Human Genome Project spawned numerous spinoff genetics projects

The Human Genome Project led to the development of techniques later applied to projects in microbial and plant biology, epigenomics, environmental and cancer genomes, and more. In the spirit of the HGP, data from these projects has been made freely available to develop new technologies.

The ancient crops we've forgotten how to grow

Roughly half of all world calories today stem from maize, wheat, and rice. But for most of history, plants were domesticated in highly local places. This video dives into the scientists learning about crops no longer highly in use that once fueled entire civilizations in North America. Some forgotten crops include pitseed goosefoot, maygrass, and sumpweed.

Where do genes come from?

There are many more genes on Earth today than when microbial life first spawned on the planet about four billion years ago. Many of these newer genes grew from genetic mutations, misprints that slowly drift from the original blueprint via cellular division. If these mutations drift far enough, they can establish a new family of genes, though this process can take well over a million years.

How MIT researchers have used genetic mutations to improve photosynthesis efficiency

Recognizing that RuBisCO—a protein that binds carbon dioxide to other compounds to produce the building blocks of organic molecules—often mistakenly binds oxygen, scientists performed directed evolution experiments to modify the geometry of a bacterial version of the protein to cause it to preferentially interact with carbon dioxide over oxygen.

The research pipelines being explored by the RIPE Project to improve photosynthesis

These include engineering plants with faster stomata, which would allow photosynthesis to resume more quickly amid fluctuations in available light due to clouds or shading from other plants, and resolving bottlenecks in the regeneration of RuBP, the molecule to which carbon dioxide is fixed during photosynthesis to initiate the Calvin cycle. (Some readers may experience a paywall.)

Bacteria helped scientists realize that DNA was the hereditary molecule, not proteins

Until the mid-1900s, most scientists believed genes were made of proteins, which were known to act as enzymes, hormones, and other chemicals that mediated an organism's traits. The Avery-MacLeod-McCarty and that benign bacteria could be made lethal, where the inherited factor that caused bacterial transformation contained DNA.

CRISPR allows scientists to cut out and replace faulty or unwanted DNA, which can help treat genetic disorders, such as sickle cell disease, and create genetically modified organisms, such as allergen-free foods.

CRISPR turns 10 years old

When Dr. Jennifer Doudna and colleagues released a paper in 2012 demonstrating the ability to harness the cell's natural immunity machinery to edit DNA, it received little fanfare. A decade later, the gene editing technology has led to innovations in medicine, evolution, and agriculture—and raised profound ethical questions about altering human DNA.

Synthetic biology can prevent extinction by creating create disease-resilient plants and animals

Through gene editing and the deployment of artificial cells, scientists can leverage learnings from the genetic sequencing of animals with known resistances to protect endangered species. Gene editing of certain species, such as mosquitoes, can also reduce their ability to spread diseases like malaria between humans.

The discovery of the first extremophile and how it revolutionized DNA analysis

While investigating samples taken from within and around the hot springs at Yellowstone National Park, microbiologist Thomas Brock discovered Thermus aquaticus, a microorganism that thrived in hot water. It contained an enzyme called Taq polymerase, a critical molecule in polymerase chain reaction—a molecular photocopier that amplifies genetic signals to improve medical diagnostics.

A timelapse of sprouting seeds

Germination is the process where an organism sprouts from a seed or spore. This timelapse captures the process in an inspiring, two-minute video so you can see the whole story of the seed quickly.

Plant hormones and growth regulators guide growth stages and responses in plants

Plants naturally produce hormones like auxin and gibberellins, while humans apply synthetic or extracted growth regulators to control plant development. These substances influence processes like flowering, root growth, dormancy, and ripening—even in very small doses.

Microbial research suggests shifts in diverse populations may help an invasive species establish itself

In 1958, English ecologist Charles Elton suggested that diverse ecosystems should be more resistant to invasive species because gaining a foothold would be more challenging when resources are more thinly spread. However, in lab-grown microbial ecosystems with greater biodiversity, population volatility opened more ecological roles that invasive species could easily fill.

Model organisms like yeast, mice, and flies help scientists decode the human body

Some species are used to quickly study the effects of human diseases and treatments because they are short-lived and have similar systems to those found in humans. Bacteria, like E. coli, have been used as human proxies given their rapid growth and ease of genetic manipulability.

Without dinosaurs, plants could produce fleshy fruits with bigger seeds

Previously disturbed by massive herbivores, denser and darker forests shifted plant evolution, reaching the greatest diversity of seed sizes, fruit sizes, and fruit types about 50 million years ago.

Gut bacteria are evolving and can acquire as many as 100 new genes per year, on average.

Research on bacterial cultures used in yogurt production led to CRISPR's discovery

Scientists learned it was a microbial immune system that could be repurposed to protect dairy cultures from viruses. Today, nearly all yogurt is made with CRISPRized bacteria, as are genetically modified crops like herbicide-resistant corn, wheat, and soy.

Long-term evolution experiments use microbe's short generations to speed up selection

With quick generations of microbes, scientists can speed up the evolutionary process, with projects like the LTEE in California running for 40 years and generating 80,000 generations of E. coli.

Distinct plant species evolved to produce caffeine as a pesticide

Although it provides a defense against insects trying to eat caffeine-bearing plants, the molecule is an example of exaptation, where its original function was repurposed over time. Studies show that some plants now produce caffeine-laced nectar to help pollinators move more quickly and pollinate more efficiently.

Did people domesticate plants or did plants domesticate us?

Humans rely on plants to survive, and many plants have come to rely on humans. This 14-minute video explores how agriculture was simultaneously a building block of civilization and a trap that captured humanity. Plant types that may not have...

Browse the prehistoric salad bar with these ancient plants

In this video, Benjamin Burger, associate professor of geology at Utah State University's Uintah Basin Campus talks about the different types of plants present during the Mesozoic Era. Professor Burger explores how these plants changed over time, served as food sources for the dinosaurs, and co-evolved with them during this period.

Scientists testing how climate change affected plants found in a yearslong simulation study that poison ivy grew 70% faster than it did without extra carbon dioxide.

Explore the independent lines of evidence behind the theory of evolution

Gradual changes in organisms have been directly observed through artificial selection—humans purposely selecting organisms to breed to pass on specific traits—and in organisms with short lifespans, such as insects and microbes. Analyses of DNA and anatomical structures across different species, as well as fossil records, also reveal ancient shared ancestry consistent with natural selection.

Chaos gardening involves scattering seeds without any planning

The trend is intended to produce colorful, dense gardens by mixing various seeds. While encouraging experimentation and lower stakes, the success of these gardens depends on choosing plants with similar needs and incorporating native, nectar-rich flowers.

The history of the gene: an interactive timeline

Humans didn’t need modern technology to figure out that kids tend to look like their parents. But what did humans believe about genetics before we knew about DNA or cells in general? Explore this interactive timeline to see how philosophers and scientists throughout the ages tried to explain how traits are passed from generation to generation.

Despite lacking a traditional nervous system, plants have specialized cells that help detect gravity, enabling them to identify which way is down to grow roots and which way is up to push shoots toward the surface.

How a single company hooked the world on herbicides

How harmful are today’s herbicides for us humans, and for the environments they’re seeping into? And do we really need weedkillers to feed the world?

Fruit fly experiments helped identify genes responsible for major body development

The insects' fast life cycle and affordability have allowed geneticists to quickly identify which genes are responsible for limbs, eyes, and other body structures by inducing mutations. The same genes may be responsible for different parts of a species' body, such as limb-building genes being responsible for wing pigmentation in butterflies.

View a collection of historical documents about molecular biology's history

The collection features materials related to those involved in the discovery of DNA and provides historical context for the discoveries of RNA, various viruses, and important bioproteins. The items include photographs, business correspondence, manuscripts, and scientific instruments.

The mystery of the cucumber, from coiling tendrils to its bitter, mature fruit

Cucumus sativus was first cultivated 3,000 years ago in the Himalaya of India, appearing in ancient Sanskrit hymns in the Hindu tradition. They are typically harvested well before maturation, as their yellow, final fruit is bitter. Their coiling tendrils were so distinct they prompted famed naturalist Charles Darwin to publish one of his lesser-known works, "On the Movements and Habits of Climbing Plants." Its refreshing coolness inspired cucumber-derived body washes and sprays over millennia.

A Death Valley shrub optimizes its cells' organelles to photosynthesize in extreme heat

Examining the cellular structure of the plant under heat, scientists observed the formation of novel, cup-shaped chloroplasts and mitochondrial relocation, which shifted the plant's optimal photosynthesis temperature to 45 degrees Celsius (113 degrees Fahrenheit) as it tripled in mass over 10 days. Engineering these mechanisms in crops may help optimize them for hotter environments.

In 2026, researchers at the University of Minnesota created the world's first synthetic cell—a cell made from non-living chemical components—that can eat, grow, divide, and compete with other cells for resources.

Iceberg lettuce was the salad staple people ate for most of the 20th century, popular due to its durability, long shelf life, and mild flavor.

How we helped make Aedes aegypti mosquitoes such a problem

Mosquito genome sequencing data suggests that Aedes aegypti mosquitoes first started specializing on human blood around 5,000 years ago—when climates shifted and humans started domesticating plants in Africa and stored large amounts of water that may have attracted the bugs.

How the Supreme Court established biotechnology patent law with an oil-eating microbe

While working at General Electric, microbiologist Ananda Chakrabarty engineered a strain of Pseudomonas that could break down multiple types of hydrocarbons and filed a patent on the bioremediation organism. Despite challenges over whether living things could be patented, the 5-4 decision held that genetically modified organisms could be patented because they were human-made inventions.

Rosalind Franklin uncovered the molecular structure of the tobacco mosaic virus

Franklin's work revealed the role of ribonucleic acid in virus infectivity, contributing to a foundational understanding of genetics and virology. Her molecular model of the virus was featured as the centerpiece at the 1958 Brussels World's Fair.

Despite privacy risks, scientists are using DNA in the air to assess ecosystem health

While DNA in soil and water samples has long been used for such analyses, airborne DNA is being incorporated into such efforts to monitor individual species abundance, detect invasive species, measure biodiversity, and determine the success of conservation actions. Future work may include detecting attacks from biological weapons.

Cell theory originated from microscopic observations of cork and dental plaque

In the mid-1600s, Robert Hooke identified compartment-like structures—which he called cells—in cork, and Anton van Leeuwenhoek discovered bacteria in samples of his dental scrapings. Almost 200 years later, Matthias Schleiden and Theodor Schwann showed that plants and animals, respectively, are composed of cells, proving that cells are the foundation of all living things.

Coevolution of pollinators and flowering plants diversified both

The first pollinators were beetles, which consumed pollen before flowering plants existed. Over time, plants evolved to attract more insects and improve the uptake of pollen, while insects adapted their biology to enhance the capture of pollen, such as developing specialized mouthparts.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

Scientists have created a cell from scratch—called a SpudCell—proof-of-concept work that a lab-made cell can feed, grow, and replicate like a natural cell.

How greenhouse gases and climate change impact the efficiency of photosynthesis

A review in the Journal of Experimental Botany found that higher temperatures reduce the efficiency of enzymes involved in photosynthesis and impair a plant's ability to control water loss and regulate carbon dioxide uptake. While increased carbon dioxide levels are understood to accelerate plant growth by boosting photosynthesis, researchers suggest these effects more than offset the potential gain.