Rome's herbal panacea may not be as extinct as we thought

Psychoactive drugs found in 1,000-year-old bag made of fox noses

Archaeologists in Bolivia have uncovered an ancient bag filled with "amazing goodies" that suggests the owner or owners were well-versed in the properties of psychoactive substances and sourced goods from well-established trade routes. This article details the findings, which shed light on how ancient peoples in the region consumed and obtained psychoactive substances.

Unraveling the charred remains of the only known library from antiquity

This article details the quest to decipher the charred remains of a library buried during Mt. Vesuvius' volcanic blast. In 1752, nearly 2,000 papyrus scrolls were found in Herculaneum. According to this article, this collection is the only complete library that has survived from antiquity. In the last decade, scientists have made strides in decoding the crumbling texts.

The ancient Romans invented the first known artificial sweetener—it involved lead.

Ancient Romans helped develop modern cheese production techniques

The ancient Romans loved cheese and experimented with different processes to elevate its flavor, like aging. Some of their innovations, like Pecorino Romano, you can still find today. Others, like the smoked goat-milk Caseus, we only know about through historical records.

The fast food shops of ancient Pompeii

Researchers have unearthed a frescoed thermopolium (a sort of hot food and drink shop) in Pompeii, the ancient Roman city frozen in time after the catastrophic eruption of Mount Vesuvius in 79 CE. This fascinating discovery provides a glimpse into Roman culinary practices and the daily life of Pompeii's citizens.

The story of Sporus, the castrated boy who married Emperor Nero

Ancient Romans’ views of homosexuality are quite different from Western understandings. Nero was an emperor is infamous for his cruelty, and appears to have heaped that cruelty upon Sporus, a boy he fell for and married in a public ceremony. As a slave, Sporus was held captive at the whims of Nero and subject to the class-based rules on same-sex relationships in ancient times.

Cleopatra was a rare female pharaoh who sided with Rome to preserve power

The figure is famous for her love affair with Roman leader Mark Antony and her suicide in 30 BCE to escape capture. Parse through the many versions of Cleopatra with more recent archaeological evidence, including a 2007 coin depicting the queen as less glamorous than historically believed.

Explore the archaeological treasures of Pompeii

Excavations revealed stunning finds—a wooden bed, a horse's saddle, and vivid frescoes—while also suggesting the eruption may have occurred in October, not April. See the discoveries from the EU's $140M Great Pompeii Project.

Ancient Romans were registered in lists of citizens to confirm their identity

Falsely claiming to be a Roman citizen was a capital offense, but taking up another identity was one way people could change their lot. Several accounts report how escaped enslaved people sought freedom by pretending to be citizens, and multiple "Neros" appeared after the real emperor died in 68 CE.

Aspirin was the first synthesized anti-inflammatory drug

Once used by the ancient Sumarians—extracted from willow bark—but now synthesized in the lab, the active ingredient of this popular medication has been used to treat headaches and pain for thousands of years.

A 101 on Pompeii

Vesuvius’ eruption in 79 CE preserved an entire Roman city in ash, leaving future archaeologists an unprecedented gift: the most complete glimpse to date into the daily life of ancient Romans. The encyclopedia entry, originally written by one of the site’s leading archaeological scholars, is a one-stop shop for all things Pompeii, including what several generations of archaeologists have discovered over centuries of excavation.

See a collection of ancient Roman coins used on the Silk Roads

As ancient Rome's appetite for eastern luxuries grew, long-distance trade routes linking the Mediterranean to Asia emerged along what became known as the Silk Road. Without shared language or legal systems, merchants could use the reliable Roman coins to exchange with other cultures. This exhibit features gold and silver pieces bearing the portraits of emperors and Latin inscriptions.

During the French Revolution, a botanist's letter asking about "dear Rhus" (poison ivy) was intercepted and led to authorities' suspicions he was conspiring with the Russians.

How did people survive the eruption in Pompeii?

In 79 CE, Mount Vesuvius erupted and buried Pompeii under roughly 20 feet of volcanic ash. This deadly eruption killed much of the city’s population, but archaeologists recently discovered evidence of survivors. In this podcast episode, classicist Steven Tuck challenges the popular belief of total annihilation and explains how people may have survived, and how they continued to live after the disaster.

The history and significance of rosemary

Rosemary is more than just an herb—it’s a powerful symbol intertwined with ancient Egypt, Christianity’s origins, Shakespeare, the culinary arts, and more. Native to the Mediterranean area, this plant has accompanied humanity for centuries, providing us with pleasant aroma, adornment, and even medicine. Explore this article for further insight into the significance of our long-standing relationship with rosemary.

The quest to find natural ways to extend lifespan

Tales of searching for the Fountain of Youth persist. Our modern-day version is marked by promises of pharmaceutical miracles and a proliferation of viral "biohacking" routines. One doctor’s quest to unlock the keys to longevity stimulated much of this renewed fervor, though his ideas are often taken out of context.

Cleopatra purportedly recommended grinding up fly heads and rubbing them on areas experiencing hair loss as a treatment.

A history of Rome and wine

Wine and winemaking were integral parts of everyday Roman life. Wine was used medicinally and for religious rites, as well as for pleasure. It also contributed to the expansion of the Roman empire as wine and grapes were traded throughout the Mediterranean. Roman winemaking practices spread as the empire grew. Without Rome, wine may never have grown into what it became, and vice versa.

The ancient crops we've forgotten how to grow

Roughly half of all world calories today stem from maize, wheat, and rice. But for most of history, plants were domesticated in highly local places. This video dives into the scientists learning about crops no longer highly in use that once fueled entire civilizations in North America. Some forgotten crops include pitseed goosefoot, maygrass, and sumpweed.

Bake bread like a Roman, and honor Ceres, the goddess of wheat

Grains made up about 70% of the Roman diet, and the word "cereal" stems from the goddess Ceres—the Roman equivalent of Greece's Demeter—to whom they prayed for good harvests. Cato the Elder, a famous statesman, left behind a simple home recipe for a Roman loaf.

Food allergies were first documented more than 4,000 years ago.

Distinct plant species evolved to produce caffeine as a pesticide

Although it provides a defense against insects trying to eat caffeine-bearing plants, the molecule is an example of exaptation, where its original function was repurposed over time. Studies show that some plants now produce caffeine-laced nectar to help pollinators move more quickly and pollinate more efficiently.

Iceberg lettuce was the salad staple people ate for most of the 20th century, popular due to its durability, long shelf life, and mild flavor.

A nearby town proved even more archaeologically important than Pompeii

Herculaneum, buried under five times more ash than Pompeii, was sealed so completely that food, furniture, and entire buildings survived. This BBC documentary reveals how its discoveries have transformed scholars' understanding of the diets, work, and social mobility of ordinary Romans.

Thermopolia were ancient Roman snack bars

Although they weren't exactly restaurants, with sit-down service or extensive menus, thermopolia were modest food counters for Romans looking for quick bites—often bread with fish, cheese, and lentils.

Oxford scientists turned Fleming’s mold discovery into medicine

In 1939, a team at Oxford—including Howard Florey, Ernst Chain, and Norman Heatley—revived Fleming’s forgotten discovery. Using makeshift equipment like bedpans and milk churns, they purified enough penicillin to prove it could treat deadly infections.

Evidence of opium use dates to as early as 5000 BCE

Archaeological evidence shows the use of the poppy plant for its pain-killing properties likely originated in the Mediterranean before making its way to the East and West via trade. It has since inspired two eponymous wars, and highly addictive derivatives of the naturally occurring substance have led to an ongoing overdose crisis.

Nero's 'Golden House' was the peak of Roman imperial architecture

Constructed on land cleared by the Great Fire of Rome in 64 CE, Emperor Nero's large "Golden House" included gilded rooms, multiple gardens, zoo-like enclosures, an artificial lake that housed a boat, and a giant statue of Nero himself. The palace was destroyed after Nero's death in 68 CE.

When exactly did Mount Vesuvius erupt in ancient Rome?

Historians used to point to the summer of 79 CE when talking about the volcano that destroyed part of ancient Rome, claiming it occurred August 24, per the sole eyewitness account. This version of Pliny the Younger's letters survived via medieval manuscripts, and other versions don't mention a date at all or give a different one: October 24. This article explores new evidence that possibly shifts the deadly disaster to that fall.

A fresco from ancient Pompeii featured an 'ancestor of modern pizza'

A team of archaeologists discovered a fresco from 79 CE featuring what appears to be a proto-pizza: a pita topped with fruit, spices, and other toppings. One archaeologist in the PBS documentary below calls it an "ancestor of modern pizza in the sense that it's a very simple, poor kind of food."

Stevia has been used to treat burns and indigestion

The substance, which is roughly 300 times sweeter than sugar and scientifically known as Stevia rebaudiana, comes from a plant that grows in Paraguay and Brazil. It has long been used medicinally and as a sweetener by indigenous communities in those locations.

Ceren: The Maya Pompeii (sans all the bodies)

The Maya village of Ceren in El Salvador was preserved by volcanic ash from 1,400 years ago, revealing insights into ancient Maya commoners' lives. Ceren villagers had autonomy in their daily activities, and excavations reveal evidence of communal decision-making and event hints at the presence of a community sauna. Dive into more of the archaeological finds on how businesses were run, how they prepared for disaster, and more.

See this searchable resource about herbal therapies, including evidence and drug interactions

Memorial Sloan Kettering Cancer Center has created this searchable resource of herbal supplements to inform the public about the purported uses of herbal therapies, the existing evidence about them, their mechanism of action, and any concerns about potential herbal supplement and drug interactions.

Synthetic opioids: a historical and clinical review

In the 19th century, researchers began synthesizing and isolating poppy plant alkaloids, leading to the invention of morphine, codeine, heroin, oxycodone, and others. These highly addictive variants eventually gave rise to illicit use and a widespread underground market, laying the foundation for the current opioid crisis.

Michael Sveda discovered cyclamate by accident

When this lab researcher brought his hands to his lips to smoke his cigarette in 1937, he tasted something sweet, which he called cyclamate. It was quickly used in diet sodas, but it was banned from the US in 1969 after being linked to rodent bladder cancer in lab experiments.

Opium is a milky liquid substance extracted from unripe poppy plant seeds

It's been used for ages to reduce pain and induce euphoria, both of which are side effects of the plant's alkaloids—nitrogen-based compounds with pronounced physical effects. Isolating and synthesizing derivatives of these naturally occurring chemicals enabled the invention of morphine, heroin, and other opioids.

Gladiators followed a mostly vegetarian, high-calcium diet

Analysis of skeletons from a gladiator cemetery at Ephesus by researchers at the Medical University of Vienna found little meat consumption but unusually high calcium levels—likely from drinking wood ash mixed with water to promote weight gain and protect vital organs.

Pompeii's buried secrets are still being revealed

Despite digging for decades, archaeologists are still uncovering new insights into life before the blast that buried Pompeii. Follow a journalist's footsteps as they explore the ruins of Pompeii in this article. The ruins were discovered in the 1700s, and formal excavations throughout the 19th and 20th centuries revealed temples, mansions, and entire streets, while a third of the city remains to be excavated.

Six 'Vestal Virgins' kept the fire burning at Vesta's temple in Rome

Ancient Rome's Vestal Virgins were priestesses of the goddess Vesta and keepers of her eternal flame, tasked with keeping the sacred torch lit as a symbol of Rome's endurance. Children from well-connected aristocratic families would be selected for the role for decades of their lives.

Supplement sales soared during the pandemic, alongside growing distrust of the health establishment, amplifying a trend that endures—even when some of the products don't even work.

When Mount Vesuvius erupted in 79 CE, it buried the Roman city of Pompeii under 20 feet of ash, which preserved it for nearly 1,700 years.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

In 1951, a small French town was likely overtaken by the fungus that ultimately led to LSD.

Mount Vesuvius' ancient Roman eruption may have literally boiled blood

Mount Vesuvius erupted in 79 CE, sending ash and debris far and wide, burying several cities and the people inside them. This article details the various ways the blast killed those in Herculaneum. This seaside town was hit with the same ash and debris as Pompeii, and it was also hit by a wave of volcanic gases estimated to be more than 500° Fahrenheit, about 260° Celcius.

See unused gladiator helmets discovered in Pompeii.

The Silk Road was an ancient series of trade routes between East Asia and Europe

Founded by the Han Chinese in 130 BCE, the Silk Road was a series of trade routes connecting eastern China with the Mediterranean and the rest of Europe. The Persians created a predecessor series of routes, but the Chinese solidified the Silk Road, where travelers traded commerce, ideas, and more.

Pompeii’s ruins expose the brutal realities of Rome’s sex trade

Drawing on graffiti, slave collars, brothel art, and the story of “Eutychis, a Greek lass with sweet ways,” this piece reconstructs the violent, coercive world of Pompeii’s enslaved prostitutes—and how their owners controlled, renamed, and exploited them.

Saccharin was banned in Canada in the 1970s, but regulators may allow its use once again

The product, commonly known as Sweet'N Low, was banned in Canada in the late 1970s due to research indicating that the sweetener could cause cancer in lab rats. Subsequent studies have found that the rodent findings didn't hold true for humans, and so Canadian regulators state that they are considering updating their stance to allow the product to be added to certain foods (the product is currently allowed in the US).

Wildlife use Rome's sprawling archaeological sites as urban havens

The Italian capital features some of the world's most famous monuments as the inheritor of ancient Rome's grandeur. This photo essay explores the city's vibrant collection of wildlife, including long-concealed native crabs, peregrine falcons, and the beaver-like nutria.

How Western psychedelics research fell to the wayside

Psychedelics' modern era began when LSD was discovered in the 1930s. By the 1950s, clinical trials were underway. US user experimentation outside of medical settings (and high-profile violence, like the Manson murders) inspired negative attitudes toward psychedelics, leading to use restrictions that prohibited companies from patenting psychedelic compounds. This strangled psychedelics' profitability until the 1990s when the government loosened its grip and psychedelics research began seeing a resurgence.