Six-year-old boy in wheelchair surprises his family by walking at his graduation

Teen who walked 6 miles to graduation receives college scholarship on the spot

Xavier Jones, a 14-year-old boy, set out to attend his eighth-grade graduation ceremony at Harris-Stowe State University, walking six miles in the hot sun. Inspired by his perseverance, LaTonia Collins Smith, the university's president, awarded him...

Bill Nye did not have children for fear of passing on ataxia

In his 2017 documentary, Nye revealed the congenital, neurological condition on his father's side of the family, which is characterized by a lack of balance and problems with fine motor movement. He has since learned he likely does not have the disease, though both his siblings have shown symptoms.

Read about the longest wheelchair wheelie and other feats in the Guinness Book of World Record's adaptive section.

Chris Nikic is the first person with Down syndrome to complete several marathons

In March 2024, Chris Nikic finished the Tokyo Marathon in 5:39:41. That was the final step towards his ultimate goal of earning the Abbott World Marathon Majors Six Star Finisher distinction. It recognizes runners who have finished Tokyo, Boston, London, Berlin, Chicago and New York.

Gene therapy for a rare type of deafness is allowing deaf children and adults to hear for the first time, according to research results reported in April 2026.

Watch this behind-the-scenes interview about the first person ever diagnosed with autism

Two reporters from The Atlantic tell the story behind their effort to track down the first diagnosed autism patient, Donald Gray Triplett, in Forest, Mississippi, and how his life turned out decades later.

The first child born via mitochondrial replacement therapy was born in 2016

The healthy baby boy's mother carried genes for a rare mitochondrial disease called Leigh syndrome and after multiple miscarriages the family opted to try the controversial procedure. It was conducted by a US doctor in Mexico. The procedure is prohibited in the United States.

In 2023, the FDA approved gene therapy for sickle cell disease, enabling one-time infusion bespoke treatments that use a patient's own stem cells to effectively cure a painful condition that disproportionately affects people of African American descent.

She can't feel pain, hunger, or danger

Olivia Farnsworth, born with a rare chromosome 6p deletion, may be the only person known to lack pain, hunger, and fear responses. This overview explores her unique condition, the incredible incidents that revealed it, and how scientists hope her case could unlock new insights into human survival and sensory systems.

The legacy of America's most remarkable kid

The short life and legacy of Kevin Cooper, a 14-year-old entrepreneur from Utah with big dreams for his family and rural America, and whose accomplishments most adults don’t pull off in a lifetime.

Defying the odds, Stephen Hawking outlived his ALS diagnosis by over 50 years

When diagnosed with ALS, Stephen Hawking was given two years to live. However, he survived with the progressive neurodegenerative disease for over 50 years, highlighting the disease's variability and complexity.

Stephen Hawking's condition explained

Diagnosed with ALS at 21 and told he had two years to live, Stephen Hawking went on to change our understanding of black holes and the universe, living 55 more years and defying every expectation.

Gene therapy is restoring hearing among kids with genetic deafness

Gene therapy for profound genetic deafness has been advancing in recent years, with multiple clinical trials enabling hearing at normal levels for the first time without hearing aids or cochlear implants. The therapies target hearing loss caused by mutations in the OTOF gene that codes for a protein called otoferlin. That protein normally plays a key role in relaying sound signals in synaptic transmission between the ear's inner hair cells and the auditory nerve.

Teenager Lamine Yamal, Spain's star footballer, was scouted at six years old.

A 19-month-old boy went viral for his natural drumming skills

A mother gifted her husband a drum set for Christmas, but was surprised to find their young child take a liking to the instrument. The musician couple noticed that over time the young boy taught himself proper form and how to keep up with the beat of the music. TikToks they filmed of their son went viral and amassed millions of views.

According to his daughter, Stephen Hawking defied early doubts about his intellect

Lucy Hawking details what it was like to be the daughter of the famed cosmologist and what his life looked like from her eyes. Among the anecdotes was Stephen's enjoyment of being on "The Simpsons" because production gave him a wheelchair with helicopter blades.

Diagnosis as an adult can have huge benefits, including helping someone with ASD to feel real

This first-person account of a woman diagnosed with autism at age 31 covers her experience of why it was useful for her to receive her diagnosis as an adult and how it helped her to understand her life and her feelings of 'being an imposter.'

See what analysis of one man's amputated leg, donated to The Bone Museum, tells us about his otherwise invisible pain.

Listen to how bionic limbs are reshaping what it means to live as an amputee in this award-winning 2022 podcast series covering the stories of two amputees who struggled with shortcomings in prosthetic technology.

Lee Spencer, a single-leg amputee, broke the world record when he rowed solo and unsupported across the Atlantic Ocean in 2019.

Interface device implanted into ALS patients restored some of their abilities

Most people with amyotrophic lateral sclerosis, or Lou Gehrig's disease, require assistance with daily life due to loss of motor control. The electrode-coated, stent-like device used motor mapping data and machine learning to translate brain activity into actions.

Gene therapy, a hope of the Human Genome Project, has successfully treated a baby born with a rare urea cycle disorder that causes toxic ammonia level buildup.

Few realized Connee Boswell used a wheelchair

The original American girl group, the Boswell Sisters, toyed with jazz standards by experimenting with challenging renditions. The group became a popular radio act during the 1920s and 1930s, with few of their fans aware that group leader Connee Boswell used a wheelchair.

How personalized gene-editing saved a baby's life

KJ Muldoon had a 50% chance of surviving a genetic mutation until doctors developed a one-of-a-kind gene-editing therapy. In an interview with one of the researchers behind the treatment, learn what it will take to make personalized genetic medicine possible for everyone.

A planned clinical trial to treat a rare lysosomal storage disorder in utero has buoyed hopes of providing prenatal gene therapies, but it was still awaiting FDA approval to begin enrolling patients as of May 2026.

Stephen Hawking's early rowing days shaped the bold persona for which he became known

Before gaining fame as a physicist, Hawking was a coxswain at Oxford, where the sport helped him find his social footing and develop leadership skills, even as his motor neuron disease began to emerge.

In 1939, baseball star Lou Gehrig delivered his 'Luckiest Man' speech after retiring due to a health condition

Gehrig's diagnosis of amyotrophic lateral sclerosis, a disease that now bears his name, forced him to retire early. Weeks later, he spoke with gratitude and stated, "For the past two weeks, you have been reading about a bad break. Yet today I consider myself the luckiest man on the face of the earth." Gehrig died at the age of 37, about two years later.

Eight British children have been born via mitochondrial replacement therapy

In July 2025, a decade after British lawmakers signed off on allowing three-parent IVF, scientists announced that eight healthy babies had already been born using this approach. The news was included in a pair of research articles published in a peer-reviewed journal that noted the oldest kids were already more than two years old, and that they were hitting developmental milestones as expected. (Some users may encounter a paywall.)

Big Ocean is breaking barriers as the world's first deaf K-pop boy band

The three-person boy band—whose members have different levels of hearing loss—use light systems, vibrations, and a mix of Korean and American Sign Languages, as well as International Sign (which isn't a whole language), to communicate and keep their dance routines in sync. In this interview, a band member with partial hearing describes their challenges.

Stem cell therapy has shown promise in treating spinal injuries in an early-stage clinical trial.

Meeting someone with common healthcare challenges can be life-changing

The understanding that comes from meeting others who have similar experiences can provide hope that life can get better, the solace of affirmation, and make navigating a new diagnosis or a rare illness, in particular, much easier.

Pediatricians look for a list of behaviors to signal typical hearing development

These markers of typical hearing development among infants and toddlers include turning head to sound sources within the first five months of life, babbling by about 11 months, and trying to imitate simple words by 17 months of age.

In 1984, a dying infant lived for three weeks with a baboon heart inside her chest.

Usher Syndrome, a rare genetic disorder, causes progressive hearing and vision loss, and people with the condition sometimes eventually become deaf and blind.

Amputees must navigate the challenging medical and economic aspects of limb support and replacement, but advances in technology and research may reduce these costs.

Toddler delivers tear-jerking speech at her mom and dad's wedding

Three-year-old Evie brought her father to tears while sharing loving words before her mother walked down the aisle.

The sibling of someone with autism has a 20% chance of developing ASD

The disorder is strongly linked with inheritance, and research suggests that if one child has ASD, there's a one in 5 chance the next child will develop autism, which is seven times more likely than the general population.

How a 6-year-old girl survived the wilderness of Arkansas alone for days

In 2001, a family trip to the Buffalo National River Wilderness in the Arkansas Ozarks took a dark turn, unfolding a tale of bizarre events when six-year-old Haley was lost and reportedly helped by the spirit of a little girl who resembled a child...

Common genetic disorders

As research continues, it's clear that disease and genetics go hand in hand. Here's a selection of 50 National Human Genome Research Institute (NHGRI) articles providing basic information on genetic, orphan, and rare diseases caused by mutations in DNA sequences, whether inherited from parents or brought about by outside factors.

How to repair a baby’s broken heart

A rare disorder that prevents some babies from getting enough oxygen to their organs can be repaired through a series of three intricate surgeries. This article and graphic explain the process behind correcting single-ventricle defects, also known as SVDs.This disorder happens when one of the heart's lower chambers doesn't work correctly, resulting in deoxygenated and oxygenated blood circulating the body rather than just the latter.

Carrier screening enables individuals without symptoms to see if they carry a gene for disease

Some conditions are autosomal recessive—meaning a person may carry a gene for that condition, but not have symptoms. Cystic fibrosis, sickle cell disease, and Tay-Sachs disease are examples of autosomal recessive diseases in which a person must inherit two copies of a nonfunctioning gene—one from each parent—to develop disease.

Autism spectrum disorder, defined in 2013, was previously categorized as numerous disorders.

‘Hope for Healing’: The first-ever use of an in utero stem cell treatment

In 2023, researchers at UC Davis performed the first-ever fetal stem cell transplant, attempting to cure a case of spinal bifida prior to childbirth using stem cells derived from the placenta. The trial, and others including an effort to treat muscular dystrophy, highlight the potential power of stem cell therapy.

A growing number of autism researchers with the disorder are reshaping the field.

Hear Aristotle Domingo, a bilateral amputee athlete, discuss his amputation journey.

Aurea is the first US baby born following polygenic analysis

The child, born in May 2020, was selected by her parents to optimize for certain health qualities based on an analysis of her multifactorial genes by a New Jersey-based company called Genomic Prediction. Her embryo was selected for implantation based on polygenic risk scores for heart disease, diabetes, and cancer.

In 2001, Little League World Series pitcher Danny Almonte was a widely praised superstar until it was revealed he was 2 years older than his competitors.

More than 90% of American deaf children are born to hearing parents

The National Institute on Deafness and Other Communication Disorders have collated top statistics about hearing loss in the US including differences by age, racial groups, and other factors.

Roughly 1 in 125 people have autism spectrum disorder globally

The disorder has been increasingly diagnosed as its definition has grown broader and as clinicians have become more adept at identifying it—with some estimates suggesting the figures are much higher. These figures include people across the spectrum, some of whom live mostly independent lives, while others require life-long care and assistance.

Here’s how different genetic disorders get passed on

The human genome is complex, as identified by the Human Genome Project. This article digs in to genetic disorders, the most common ones, and how they are diagnosed.