Red light therapy—a treatment harnessing a specific form of energy that penetrates the top layers of skin—is marketed for skincare and wellness, but has its roots in NASA plant growth research.

High-powered red light therapy—delivered directly to nerve fibers via a fiber optic needle—has been used in recent experimental research to suppress pain.

Certain visible light therapies, when applied at specific intensities, can be used to treat skin conditions, including acne.

This 1440 Original video dives into what the science says about phototherapy and its various potential applications.

NASA began investigating the healing properties of red light therapy in the 1980s, when researchers studying how LED lights could aid in photosynthesis noticed that their hands seemed to heal faster than normal under the lights.

In 2026, the US FDA approved a light-activated gel combined with red light therapy as a nonsurgical treatment option for the most common type of skin cancer.

A 1974 Science News article proclaimed that within a decade, light therapy would be on par with traditional drugs.

See photos of ultraviolet light therapy, widely administered in the early 1900s, particularly among children with skin diseases, tuberculosis, rickets, and more.

The design of a psychiatric ward in Norway aims to integrate more circadian rhythm-friendly lights as part of its treatment protocols for conditions including psychosis, severe depression, and more.

Light therapy was widely used as a medical treatment for various maladies in the early 1900s before it was replaced by antibiotics.

Laser skin treatments can promote the production of collagen

Skin resurfacing vaporizes the top layer of skin to reveal healthier, new skin, while collagen can give the skin structure and elasticity. Such procedures treat scars and burns, but may leave light spots on the skin.

Early research suggests CAR-T therapy might treat scleroderma, reducing skin thickening

Clinical data from a couple patients in 2025 indicated that one experimental CAR-T therapy called rese-cel was able to genetically reprogram T cells to eliminate certain problematic immune B cells that were causing the condition. The therapy reduced skin thickening and allowed the patients to halt using immunosuppressive medications and steroids.

Photodynamic therapy is one current treatment for age-related macular degeneration.

Bright light therapy involves basking in 10,000 lux of light for 30 minutes each morning

Nothing is better than going outside and soaking up real sunlight. However, this is harder in winter, especially in very cold and cloudy regions. SAD lamps are designed to project 10,000 lux—a unit of illuminance, or how much light actually hits a surface (rather than how much is produced, like watts). This video discusses product options and practical considerations.

Blacklights can illuminate certain biological materials, including blood, teeth, and fingernails, because they contain fluorophores—molecules that visibly glow immediately after exposure to higher-energy light.

Biohacking to boost personal health has become a concept that encompasses everything from vitamin regimens and cryochambers to brain implants and red light therapy.

Stem cell therapies

Stem cells' special attributes interest researchers developing new therapeutic tools for a variety of health problems. Much of this research is done with support from the National Institutes of Health (NIH). This page offers a snapshot of research programs funded by the NIH and the health problems those programs focus on.

Bioluminescent reaction enzymes are often used in biomedical research

Near-infrared luciferase systems allow researchers to image and analyze cellular activity in living animals because they penetrate tissue more deeply than visible light. This provides a means of studying gene expression and protein interactions without harming the animals.

Infrared light is most often associated with thermal radiation and cooking food

Although extensively used in remote controls for electronics, where LED lights send signals wirelessly, infrared cameras allow for night vision and thermography—imaging of heat patterns in the body to non-invasively reveal blood flow for supplementary diagnostics. Infrared radiation also provides heat in toasters, saunas, and other technologies.

Unlike America's recommendations, Australian authorities don't encourage routine sunscreen use for darker skin tones—reasoning that melanoma risk is low, and it's better to get UV exposure to help the body naturally produce vitamin D.

Jaundice, which can make the skin and eyes appear yellow, is a buildup of bilirubin, a waste product that forms when old red blood cells break down.

Virtually all plants are biofluorescent because their photosynthesis is powered by chlorophyll, a pigment that glows red as a way to get rid of excess energy when exposed to ultraviolet light.

Peptide TB-500, promoted for regenerative healing, is not FDA approved

Watch a board-certified sports medicine therapist detail his thinking about this synthetic peptide; he says it's "promising but unproven." He notes that this product is designed to mimic the natural protein thymosin beta-4, found in human and animal tissues, which promotes wound healing. TB-500 is classified as a research peptide for recovery, meaning it's not approved for human use and has not yet undergone rigorous human trials on its safety and efficacy.

Scientists using gene therapy recently managed to regenerate retinal cells in the lab—a breakthrough for mammals that could potentially lead to future treatments for human retinal diseases.

Can microdosing improve mental health?

Animal studies involving microdoses of psilocybin, the psychoactive component in magic mushrooms and ketamine, found it helped to alleviate anxiety and inflammation, an immune response that can cause damage when chronically active. Human studies are ongoing. In at least one double-blind study, where researchers and patients don't know who got a placebo versus the real thing, about half of the participants incorrectly guessed they had been given placebos.

Radio waves are used in broadcasting, weather radar, telecommunications, and GPS

Its ability to bend around obstacles and reflect off the ionosphere—an electrified layer of Earth's upper atmosphere—allows this type of light to travel long distances without damaging living things due to its low energy. MRI scanners, WiFi, and Bluetooth technologies are also applications of this form of light.

Frequently asked questions on immunotherapy

The Cancer Research Institute takes a close look at immunotherapy and its potential for treating cancer. Immunotherapy teaches the patient's own immune system to recognize and fight cancer cells. It's especially promising as an alternative for cancers that resist chemotherapy and radiation treatment. Have all your questions about the process and its promise here.

Collagen supplements have become a multibillion-dollar industry

Beginning in our 20s, the amount of this protein in our skin, muscles, and connective tissue declines. But independent, high-quality studies—like those that are double-blind—have not yet shown a significant association between their use and evidence of it improving skin elasticity, reducing wrinkles, or combating hair loss. Some collagen supplements do seem to help with joint pain and knee function, but NPR cautions that studies on that purpose are industry-funded.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Starting with red, colorful objects will appear to lose their colors the deeper they are submerged because water scatters light, reducing the amount available to reflect off objects and be observed.

Skull bone marrow may be playing a key role in chronic pain.

Why CAR-T therapy has become one of the main focus areas for autoimmune diseases

The therapy, originally targeting cancer, involves taking a patient's own T cells, genetically reprogramming them to recognize and attack a specific target and then infusing them back into patients. For autoimmune diseases, the therapy instead programs them to target immune cells that are causing problems, restoring immune system tolerance.

An overview of modern clinical research on LSD

Researchers have determined that LSD, taken in a medical setting, decreases anxiety related to "life-threatening disease," reduces brain reactivity to fearful faces, increases the meaning and emotional response derived from music, and more. No complications of LSD administration have been observed in medical settings, though acute adverse effects, including exhaustion, nausea, and difficulty concentrating.

Remylination is a huge focus for treatment—especially among older adults

Our ability to build new myelin sheaths for nerves degrades with age. There have been research advances boosting cells that support these processes and clear away debris from degraded myelin, but not yet any medications to boost myelination itself, which would aid nerve signaling and preserve nerve function.

See this 201-level explanation about mitochondria and mitochondrial replacement therapy

This 2022 academic presentation from Stanford University's Dr. Gregory Enns offers a detailed overview about mitochondrial therapy approaches. Enns, a pediatric geneticist, explains how well-functioning mitochondria support the human body.

The chlorophyll in plants captures energy in the form of red and blue light

Light-dependent reactions during photosynthesis convert sunlight into chemical energy, stored within the bonds of molecules such as ATP and NADPH. Rather than being absorbed for these reactions, most green light is reflected, causing most plants to appear green.

Targeting cholesterol metabolism may help address macular degeneration.

Stress contributes to gray hair because when the body experiences stress, the sympathetic nervous system releases specific hormones that influence pigment-producing cells.

The origin of LASIK eye surgery, from a lab incident to federal funding and widespread use

After a University of Michigan engineering student suffered retinal burns from an ultrashort pulse laser, researchers realized it could be used to reshape the cornea and improve a person's vision with greater precision than a scalpel and earlier laser technologies. Agencies, including the National Science Foundation, the National Institutes of Health, and the Department of Energy, provided funding to develop and commercialize the procedure.

The US FDA issued a 2025 warning about BPC-157 and other popular peptides that are marketed for various regenerative properties.

The weakest form of light that is dangerous to humans is ultraviolet

Unlike radio waves, microwave, infrared, and visible light, UV light can produce chemical changes, such as curing adhesives and resins, causing substances to fluoresce, and destroying the genetic material of microorganisms. This makes UV light useful for sterilization, forensics, and quickly drying nail polish.

'Magic ink' is redefining the tattoo

One University of Colorado professor has developed an ink that can be "turned on" with exposure to UV light, and "turned off" with sunlight. While the ink could help those who want to hide their body art from family members or coworkers, there are potential uses for medical procedures.

GLP-1s are netting interest for treating autoimmune diseases, but are considered experimental

Already used to treat type 2 diabetes, the novel medications are showing some early promise in experimental studies at reducing inflammation and treating autoimmune conditions including rheumatoid arthritis and inflammatory bowel conditions. But researchers caution that side effects are still under investigation—rarely the medication has caused lupus, an autoimmune disease.

Particle beams can be used to alter the surface properties of artificial joints

Surface hardening and embedding specific elements or coatings can improve the biocompatibility and bone tissue integration of these implants. Particle accelerators are significant sources of the radioisotopes needed in medical diagnostics, and microwave linear accelerators are used in the majority of cancer irradiation treatments.

The US FDA considered mitochondrial replacement therapy during 2014 hearings

An agency committee assessed if this approach could have undesirable ripple effects across multiple generations and whether a clinical trial involving this approach would be appropriate. As of 2026, the US has continued to prohibit this procedure though it is legal in other settings including the UK and Australia.

Imagining if humans could perform photosynthesis and how it would change our anatomy

Since chloroplasts reflect green light, becoming photosynthetic would give our skin a green appearance. Because photosynthesis has efficiencies of only 5% to 9%, and humans burn 2,000 Calories daily compared to about 200 burned by a tree, becoming photosynthetic would also require us to adopt a less active, sun-filled lifestyle.

The commercial and therapeutic potential of psychedelics

A 2006 study into the potential therapeutic benefits of psychedelics sparked a renewed interest in the field of psychedelic research, a development that has cascaded into commercialized ventures and experiences. This article details how growing research into the psychological benefits of psychedelics is matched by the rise of anecdotal reports, book deals, businesses, and corporate claims seeking to capitalize on psychedelic potential.

Addressing lifestyle factors, which influence inflammation, can cure some chronic diseases

In this video, a physician claims that he reversed a patient's Type 2 diabetes in six weeks by addressing inflammation drivers such as diet. More broadly, he argues that society needs to better consider and address numerous disease factors that are modulated by inflammation, such as stress, sleep, diet, and movement.

Researchers are investigating how altering the gut microbiome may influence the development of rheumatoid arthritis, which is an autoimmune disease.

Scleroderma, which causes skin to harden and scar, has no FDA-approved treatment

It's an autoimmune disease that disproportionately causes worse complications in African American people for unknown reasons. It causes the body to overproduce collagen after the immune system attacks the body's own connective tissue, leading to excess collagen deposits and restricted blood circulation as small blood vessels are damaged. It can damage various organs, including the lungs.

Psychedelic side effects, including worsening mental health for some patients, give pause

This article explores whether the therapeutic potential of psychedelic drug use is really as good as current research suggests. Scientists are exploring its applications for conditions ranging from the existential crisis that can accompany terminal diagnoses to chronic mental health conditions, including anxiety and PTSD.