Microgravity environments improve the success of 3D bioprinting

Microgravity can alter the evolution of viruses and bacteria

Experiments conducted on the International Space Station have shown that microgravity environments can delay viral and bacterial infections and induce mutations not seen on Earth. These mutations could have implications for long-term space missions and human health and suggest space can serve as a testing ground for developing new therapeutic approaches.

Microgravity environments reduce muscle mass and bone density

Muscles that assist with balance and resistance to gravity are not subjected to their usual workload on the International Space Station. See the type of exercises that astronauts must complete for roughly two hours daily, and learn why these movements are necessary to preserve astronauts' muscles, bones, and cardiovascular health.

How 3D printing inside cells paves the way for microscopic machines

In 2026, scientists in Slovenia developed a method to 3D print a small elephant, several microscopic geometric objects, and barcodes for cell labeling within living human cells, which continued to grow and divide thereafter. The experiment opens the door to fabricating devices within cells to study and manipulate cellular functions.

Medical imaging allows 3D printers to create patient-matched devices

With imaging data on a person's anatomy, external prostheses and implants, such as cranial plates or hip joints, can be custom-printed to better match a patient's body. Fabrication of porous structures can promote bone growth, leading to longer-lasting implants.

Watch what it’s like to spend a day on the International Space Station

Microgravity makes personal care more complex on the International Space Station, where stray, floating materials must be captured to prevent them from entering vents and clogging filtration vents. No-rinse shampoo, water pouches, and other strategies help minimize obstructions.

Drugs in space: the pharmacy orbiting the Earth

Researchers are developing pharmaceutical solutions for astronauts, whose bodies may not respond the same way in space as they would on Earth. Similar to how microgravity causes changes to astronaut physiology, the environmental shift enables new...

Technologies developed for the ISS have brought benefits to people on Earth

About 93% of water used onboard the International Space Station is recycled through filtration and purification systems that have since been used in regions lacking access to clean water. Treatments to mitigate bone loss and muscle atrophy in astronauts can also help aging adults.

Research suggests the cleanliness of the ISS may make astronauts unhealthy

The International Space Station's sterile conditions deprive astronauts of the opportunity to strengthen their immune systems through microbial exposure. To address this problem, future missions may use probiotic-based cleaners and foster diverse microbes in space habitats.

As of 2025, perfect synthetic replication of natural organs remains elusive

Advancements such as 3D printing muscles, performing vaginal reconstruction with colon tissue, and growing organs in a lab have shown promise, but artificial options and transplanting substitutions continue to exhibit functional and performance limitations compared to their natural equivalents.

There are no established minimum fitness standards for spaceflight

Microgravity is known to cause arterial hardening, bone weakening, and other health issues, but the novelty of space tourism and the minimal exposure time for suborbital trips have limited the number of research studies. Many companies have participants sign extensive waivers to bypass the requirement of specific medical standards.

It is impossible for astronauts to burp in space

Due to Earth's gravity, liquids and solids sink in our digestive system, while gases rise, allowing them to be forced back up the esophagus to be expelled through burping. In the microgravity environment of the International Space Station, burping would result in vomiting if it were possible.

Software subscriptions, licenses, and climate control systems add to 3D printing costs

Although the sharing of designs and reduced manual labor suggested the fabrication of prosthetics would be facilitated by 3D printing, particularly in developing regions, software and hardware requirements have posed hurdles to achieving this goal. While some insurance companies have refused to cover 3D-printed limbs, they are covered by Medicare.

NASA funded research into creating pizza with a 3D printer

The agency awarded a contract for the development of devices that can create edible structures from long-lasting dry powders when mixed with liquids or pastes. By delaying this integration until the time of consumption, food could last longer than the current six-month expiration of freeze-dried meals for Mars expeditions.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

Astronauts on the International Space Station have tested an algae-powered bioreactor that converts carbon dioxide, water, and light into oxygen and edible, protein-rich biomass.

Using fitness wearables to track muscle wasting in astronauts

All that exercising, and astronauts still are likely to lose a large amount of muscle mass while in microgravity. Astronauts can lose up to 20 percent of their muscle in as little as five days in space. Currently, tracking muscle loss means waiting until astronauts land to remeasure their muscle density post-trip. This article explains a NASA-backed fitness wearable that may be able to track muscle atrophy as it happens.

The benefits of 3D printing batteries, from safety to sustainability

Rather than using the liquid electrolyte commonly found in lithium-ion batteries, 3D-printed batteries would use a solid layer, which can be custom-built into different shapes, deliver higher energy density by building thinner layers, and be fabricated with fewer raw materials compared to injection molding.

Watch the engineering challenges overcome in turning a 3D printer into a tattoo machine

The DIY project required reprogramming the printer to operate on a curved, 2D surface rather than making flat layers in 3D, editing replacement firmware to bypass temperature safety checks, and developing a rapid system to stop the tattoo in case of an emergency. The final product printed "LEG" on a volunteer's leg.

Chip-based 3D printers can be pocket-sized and involve no moving parts

Researchers have demonstrated a proof-of-concept version of a chip-based 3D printer that emits visible light onto light-sensitive resin to construct solid shapes. The technology may provide a portable, low-cost solution for future, small-scale fabrication needs.

Prosthetics and orthotics have been 3D printed to improve the lives of animals

Shells for hermit crabs, wheelchairs for guinea pigs and dogs, and horseshoes for improved running performance have been created using 3D printers. Other artificial body parts made using this technology include a jaw for a loggerhead turtle, a beak for a toucan, and a tail for an American alligator.

Organoids: 3D organs grown from stem cells in the lab

An organoid is a three-dimensional construct composed of multiple cell types that originate from stem cells that can simulate the architecture and functionality of native organs. One big benefit of these lab-grown organs is that drug candidates can be tested in model systems without needing live patients.

Multi-material 3D printing produces filament waste if only one nozzle is used

When swapping between colors or materials in a fused deposition modeling system, a considerable amount of filament is purged from the nozzle before introducing a new filament. Filament extruders can create new filament from purged elements, but the device combines colors and produces filaments of inconsistent diameter.

Watch the iterative process of successfully printing a slice of vegan cheesecake

3D printing food requires integrating ingredients with a variety of properties, which may not all resist the physical stress of stacking. This means successful 3D printing of food may require rethinking how ingredients are layered and modifying ratios of each, potentially sacrificing taste for structural integrity.

Mold growth in space raises the hypothesis of life being brought to Earth

Panspermia suggests that life could be carried throughout the cosmos by asteroids, comets, and other objects, but it requires organisms that can withstand the extreme cold of space travel, stellar radiation, lack of water, and intense heat of planetary impacts. The discovery of mold on the International Space Station and experiments showing it can withstand radiation in outer space-like conditions increase the plausibility of the hypothesis.

How to make a burrito in space

Just because you’re living at the International Space Station doesn’t mean your cravings disappear. In this video, Chef Traci Des Jardins explains the best way to make a burrito while experiencing microgravity.

Gravity assists are crucial for space travel beyond Mars

By traveling near a moving celestial object, a passing object can gain or lose speed and change direction due to the acceleration provided by their mutual gravity. Some missions are planned around spacecraft performing multiple assists, or slingshots, to reduce fuel requirements for long-distance travel.

Astronauts exercise on the International Space Station

Astronauts maintain bone, muscle, and cardiovascular health with physical activity. It's crucial that they make time to exercise for approximately two hours per day. This resource offers a behind-the-scenes look at how high-intensity workouts help prevent muscle atrophy, bone density loss, and aerobic decline during monthslong space missions.

Most custom earmolds for in-ear hearing aids are made using 3D printing

The technology has also been utilized for behind-the-ear and receiver-in-canal hearing aids, allowing for the creation of structures tailored to the patient's anatomy for enhanced effectiveness. 3D printing has also been used to print retinal eye cells and custom eyeglass frames.

Understanding why suction cups rely on Earth's atmosphere to work

When pressed against a surface, air is squeezed out of a sealed volume, causing the internal pressure to drop below the surrounding atmospheric pressure, and this imbalance creates the "sticking." For this reason, astronauts do not use suction cups or related technologies to stay on spacecraft during spacewalks.

The 3D-printed rocket maker competing with SpaceX

Producing rockets cheaply and at scale may require atypical manufacturing processes like those developed by Relativity Space, a 3D-printer of rockets. Relativity hopes to not just compete with, but beat, SpaceX in the race to get the first...

In 2015, the FDA approved the first 3D-printed prescription tablet

Spritam, an epilepsy medication, had been too large and difficult to swallow, particularly due to its inability to dissolve easily. The new pill was designed with porous layers to enhance its dissolvability, paving the way for future 3D printing of drugs.

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.

Massive 3D printers have been used to build homes by stacking layers of 'concrete toothpaste,' a fire-resistant material that effectively insulates against outside noise.

Learn how environmental conditions are optimized to increase bioremediation efficacy

Through biostimulation, Indigenous microbes are provided with moisture, nutrients, or oxygen to prevent their death and ensure optimal progression of their biochemical reactions. Bioaugmentation can introduce new microbial cultures to target specific compounds not natively found in the environment, while landfarming can spread or aerate contaminated soil to improve access to contaminants.

As of 2025, the Factory of the Future 1.0 is the world's largest 3D printer

Housed at the University of Maine, the machine incorporates AI and can utilize bio-based materials to construct homes exceeding 3,000 square feet in size. Homes made from these materials are fully recyclable, as their components can be deconstructed, ground up, and reused as raw materials for printing.

NASA has partnered with several private companies to promote commercial space stations

The retirement of the International Space Station in 2030 has led NASA to refocus its efforts on continuing microgravity research through private partnerships, including the support of multiple commercial space stations' design and development.

Since 2019, a free-floating robotic system named Astrobee has helped astronauts with routine tasks on the International Space Station.

Muted smell and taste in microgravity complicate meal enjoyment

Astronauts primarily consume freeze-dried meals, which are rehydrated with water recycled from urine and perspiration, directly from bags. Condiments and select cultural items from crew members can enhance the meal experience by boosting flavor. Many individuals report experiencing "food fatigue" due to a lack of fresh produce, limited menu variety, and lingering scents.

Explore a library of data files for 3D printing

Data files are organized by category, including gadgets, learning, and fashion, with most available in .stl format, which is native to computer-aided design software, and presliced. Some files are also available in .3mf, an open-source file format developed as a universal standard for high-fidelity 3D printing.

Thingiverse is a massive free library of 3D-printable designs

The site—which was launched in 2008 by 3D-printer manufacturer MakerBot—hosts more than 2 million user-generated design files to build everything from prosthetic hands to replacement dishwasher parts (or the "Golden Snitch" from "Harry Potter). The community behind it rapidly designed and shared files for face shields and ventilator components amid the COVID-19 pandemic.

Biological terraforming studies have been conducted at Biosphere 2

The experiments involve populating barren hillslopes within the Landscape Evolution Observatory with microbes that react with air and rock to produce molecules needed by more complex organisms. Mosses and other simple plants can then grow in these spaces, gradually making them more hospitable to humans.

NASA uses extreme Earth environments to prepare for space exploration

Analog missions in volcanic terrains and craters mimic Martian and lunar environments. Crew members operating in these missions, including at sites in Utah, Nevada, Arizona, and Hawai'i, test suits and specialized space instruments under simulated conditions.

Oxygen is produced in the International Space Station from recycled water, which is split into hydrogen and oxygen gases using an electric current.

Prolonged space travel significantly impacts multiple human body systems

Astronauts can lose 20% of their muscle mass after two weeks and 10% of their bone mass after six months in space. Decreased sharpness of eyesight and changes in neural connectivity, brain structure and gut bacteria have also been observed.

Watch a time-lapse of 3D printing a Groot figurine

The total printing time on the Prusa i3 MK2 printer was 12 hours and 32 minutes, with the head alone taking nearly 5 hours to print from layering plastic filament.

Watch how dozens of everyday human tasks are performed in space

This playlist features clips of astronauts aboard the International Space Station explaining how they cook, eat, sleep, and conduct research in microgravity. Other activities to pass the time, including watering plants and playing soccer, are also shown.

How helium enables MRI machines to look inside organisms

By cooling the machine's magnets with liquid helium to extremely low temperatures, they can generate and maintain powerful magnetic fields that align the hydrogen atoms in living things to point toward a patient's head or feet. A radio pulse nudges these atoms, which realign and induce a measurable signal in nearby electrical coils. These signals are captured in slices and then stacked into a 3D reconstruction.

3D printers can create nearly any object that can be digitally designed

Limited only by the size of the printer and the properties of the materials used for printing, fabrications, including household items, toys, props, cases, prototypes, and models, can take anywhere from fractions of an hour to several days to make, depending on design complexity, size, color changes, and printer settings.

Astronauts follow strict schedules to mimic Earth days and stay healthy in space

Experiencing 15 sunrises and sunsets a day while aboard the International Space Station, visitors preserve their circadian rhythms and mental health with fixed timetables. Astronauts have described sleep as living in a vacuum cleaner due to ongoing air filtration.

3D printing has made musical instruments more accessible

Violins fabricated from durable plastic, rather than being built from wood, can cost hundreds of dollars less, allowing children to try them out without financial pressure. They can be made in colors that appeal to children, sizes tailored to their bodies, and with tactile guides to help visually impaired learners.