Drugs in space: the pharmacy orbiting the Earth

Protecting astronauts against space radiation

Outside the protective atmosphere of Earth, astronauts are constantly bombarded by radiation, which, among other dangers, increases the risk cancer. While those of us on Earth can mitigate the effects of similar radiation by limiting exposure,...

Watch what it’s like to spend a day on the International Space Station

Microgravity makes personal care more complex on the International Space Station, where stray, floating materials must be captured to prevent them from entering vents and clogging filtration vents. No-rinse shampoo, water pouches, and other strategies help minimize obstructions.

Civilians on short-term spaceflights can experience long-term astronaut health impacts

A collection of 44 studies—primarily based on data from a 2021 tourist trip to low Earth orbit—identified immune system disruption and some kidney damage in tourists, with women appearing to recover from space travel faster than men. Return trips from Mars may require human travelers to be on dialysis.

Microgravity can alter the evolution of viruses and bacteria

Experiments conducted on the International Space Station have shown that microgravity environments can delay viral and bacterial infections and induce mutations not seen on Earth. These mutations could have implications for long-term space missions and human health and suggest space can serve as a testing ground for developing new therapeutic approaches.

Research suggests the cleanliness of the ISS may make astronauts unhealthy

The International Space Station's sterile conditions deprive astronauts of the opportunity to strengthen their immune systems through microbial exposure. To address this problem, future missions may use probiotic-based cleaners and foster diverse microbes in space habitats.

How do astronauts battle loneliness and depression?

You’re stranded hundreds of miles away from your friends and family, constantly surrounded by coworkers who also are your roommates, and you’re only allowed the shortest of walks outside. There’s also no takeout, and gravity has essentially broken up with you. You might need a little help adjusting mentally. That’s where space psychologists and psychiatrists step in, according to this article.

Prolonged space travel significantly impacts multiple human body systems

Astronauts can lose 20% of their muscle mass after two weeks and 10% of their bone mass after six months in space. Decreased sharpness of eyesight and changes in neural connectivity, brain structure and gut bacteria have also been observed.

Astronauts follow strict schedules to mimic Earth days and stay healthy in space

Experiencing 15 sunrises and sunsets a day while aboard the International Space Station, visitors preserve their circadian rhythms and mental health with fixed timetables. Astronauts have described sleep as living in a vacuum cleaner due to ongoing air filtration.

Watch how dozens of everyday human tasks are performed in space

This playlist features clips of astronauts aboard the International Space Station explaining how they cook, eat, sleep, and conduct research in microgravity. Other activities to pass the time, including watering plants and playing soccer, are also shown.

There are no established minimum fitness standards for spaceflight

Microgravity is known to cause arterial hardening, bone weakening, and other health issues, but the novelty of space tourism and the minimal exposure time for suborbital trips have limited the number of research studies. Many companies have participants sign extensive waivers to bypass the requirement of specific medical standards.

Astronauts have used a small portable device to take the first-ever X-rays in space, opening the door for new opportunities for aerospace medicine.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

Using fitness wearables to track muscle wasting in astronauts

All that exercising, and astronauts still are likely to lose a large amount of muscle mass while in microgravity. Astronauts can lose up to 20 percent of their muscle in as little as five days in space. Currently, tracking muscle loss means waiting until astronauts land to remeasure their muscle density post-trip. This article explains a NASA-backed fitness wearable that may be able to track muscle atrophy as it happens.

Microgravity environments reduce muscle mass and bone density

Muscles that assist with balance and resistance to gravity are not subjected to their usual workload on the International Space Station. See the type of exercises that astronauts must complete for roughly two hours daily, and learn why these movements are necessary to preserve astronauts' muscles, bones, and cardiovascular health.

Has anyone had sex in space?

Reproduction is a basic human function, and while we've spent decades in space, no research has been done into the process. With many discussing the possibility of human-occupied bases on the moon, Mars, and more, understanding how sex works outside...

Technologies developed for the ISS have brought benefits to people on Earth

About 93% of water used onboard the International Space Station is recycled through filtration and purification systems that have since been used in regions lacking access to clean water. Treatments to mitigate bone loss and muscle atrophy in astronauts can also help aging adults.

Astronauts exercise on the International Space Station

Astronauts maintain bone, muscle, and cardiovascular health with physical activity. It's crucial that they make time to exercise for approximately two hours per day. This resource offers a behind-the-scenes look at how high-intensity workouts help prevent muscle atrophy, bone density loss, and aerobic decline during monthslong space missions.

Muted smell and taste in microgravity complicate meal enjoyment

Astronauts primarily consume freeze-dried meals, which are rehydrated with water recycled from urine and perspiration, directly from bags. Condiments and select cultural items from crew members can enhance the meal experience by boosting flavor. Many individuals report experiencing "food fatigue" due to a lack of fresh produce, limited menu variety, and lingering scents.

It is impossible for astronauts to burp in space

Due to Earth's gravity, liquids and solids sink in our digestive system, while gases rise, allowing them to be forced back up the esophagus to be expelled through burping. In the microgravity environment of the International Space Station, burping would result in vomiting if it were possible.

Microgravity environments improve the success of 3D bioprinting

Gravity can cause gaps, such as those in the chambers of a 3D-printed heart, to collapse before stem cells, hydrogels, and biochemicals bind together during the bioprinting process. Rather than Earth's surface, some bioprinting is done on the International Space Station, where defective organs are also printed to test treatment methods.

Emulating Earth’s light-dark cycle is important for astronaut health and safety

Astronauts aboard the International Space Station experience 16 daily sunrises, but scientists have learned to try to promote circadian rhythms by phasing through several light settings aboard the ISS to improve astronauts’ sleep and productivity.

Astronauts on the International Space Station have tested an algae-powered bioreactor that converts carbon dioxide, water, and light into oxygen and edible, protein-rich biomass.

Watch the Space Olympics from the International Space Station

From "synchronized space swimming" to "weightless sharpshooting," crew members in 2021 competed in microgravity versions of events from the summer Games. The "lack-of-floor routine" featured mid-air gymnastics as astronauts floated through space station modules.

A 'holoported' medical team has been beamed into the International Space Station

In 2021, using the Microsoft HoloLens Kinect camera and custom Aexa Aerospace software, NASA's flight surgeon led a team of hologram doctors on a pioneering visit to the space station, marking a significant advancement in communication and telemedicine technologies that will be crucial for future deep-space missions.

Tardigrades have not been shown to survive all space conditions at once

A 2007 mission launched several species into low-Earth orbit, exposing them to microgravity in temperature-controlled modules. Survivability rates were high for microgravity exposure alone, but plummeted when combined with exposure to the full UV spectrum and the vacuum of space.

Five hazards of human spaceflight

From space radiation to isolation, humans struggle when it comes to traveling and living in space. What does this mean for long-term spaceflight? This hour-long podcast episode attempts to answer that question while detailing five major spaceflight hazards.

NASA worries about the reactivation of dormant viruses during missions—particularly the virus that causes shingles—because spaceflight suppresses the human immune system and elevates stress hormones, making it more challenging to stay healthy.

How to make a burrito in space

Just because you’re living at the International Space Station doesn’t mean your cravings disappear. In this video, Chef Traci Des Jardins explains the best way to make a burrito while experiencing microgravity.

NASA uses extreme Earth environments to prepare for space exploration

Analog missions in volcanic terrains and craters mimic Martian and lunar environments. Crew members operating in these missions, including at sites in Utah, Nevada, Arizona, and Hawai'i, test suits and specialized space instruments under simulated conditions.

A look at the foods eaten by astronauts during and after the space race

After John Glenn became the first American to demonstrate that eating in space was possible by eating apple puree out of a tube, meals were prepared for astronauts to meet an approximately 2,800-calorie-a-day requirement via freeze-dried foods. Meal quality gradually improved throughout the Apollo program, including the Apollo 8 crew's nondehydrated Christmas meal in 1968.

What is space sickness?

Mix motion sickness minus gravity with a host of other variables, and you’ve got a recipe for space adaptation syndrome. It can hit anyone, even astronauts who escaped the issue previously. This article details the history and science behind space sickness.

Mold growth in space raises the hypothesis of life being brought to Earth

Panspermia suggests that life could be carried throughout the cosmos by asteroids, comets, and other objects, but it requires organisms that can withstand the extreme cold of space travel, stellar radiation, lack of water, and intense heat of planetary impacts. The discovery of mold on the International Space Station and experiments showing it can withstand radiation in outer space-like conditions increase the plausibility of the hypothesis.

We don't know why astronauts get motion sick

Between 60% and 90% of astronauts get motion sick in space—and many also get motion sick during the first few days upon return. Motion sickness on Earth does not seem to correlate with whether or not astronauts get motion sick in space, so it's not possible to predict who will get ill.

The space race of the 21st century is focused on a permanent lunar outpost

After decades of dormancy, NASA and SpaceX hope the Artemis program will provide opportunities for lunar resource extraction. Countries like India, China, and the UAE have also shown interest in developing future lunar economies.

30 everyday inventions originally created for space

In their pioneering work to develop the technologies necessary for humans to inhabit space, NASA and its counterpart agencies around the world have produced dozens of products millions of people use everyday. Some of these are obvious, like water filtration systems and wireless headsets, while many are surprising, like artificial limbs and insulin pumps. Dive into the list here.

Increasing space tourism may require changing the definition of astronaut

Though astronaut has been used to describe any crew member in space, civilian explorers who lack formal training have instead been dubbed "space travelers" by some. The term astronaut may one day fall out of use or be modified by ongoing media and social perceptions as the space tourism industry continues to evolve.

Scientists determine the smells of objects in outer space

Using spectrographic techniques, scientists determine the chemical composition of planetary atmospheres, comets, and other objects in space. Combining these chemicals in labs on Earth has revealed locations in space that smell like nail polish remover, rotten fish, and urine.

Space travel sparked inventions we now use every day

Technologies developed for space exploration produced lasting spinoff innovations—from camera phones to memory foam—displaying how the space race reshaped everyday life here on Earth

About 10% of the radiation people are exposed to each year comes from outer space, with higher percentages for those living at higher elevations or who fly often.

Watch a montage of space-based Earth views as astronauts discuss their overview experiences

As of 2023, more than 600 astronauts and 63 space tourists have seen Earth from space, experiencing a life-changing perspective shift as they view the entirety of our home planet.

Longer-duration space missions may amplify astronaut motion sickness

NASA is using the Kraken, a 50-foot-long, 100-ton US Navy research device, to simulate space motion sickness and vertigo and test possible recovery strategies, including testing out different, specific head movements. The Kraken, located at Wright-Patterson Air Force Base near Dayton, Ohio, can rotate participants at exposures of up to 3G.

Who’s in space right now?

Hundreds of people (and a few animals) have been to space since the first creatures flew past the Kármán line in 1947. There are a handful of astronauts aboard the International Space Station at any time, while others may be cresting space in...

NASA has partnered with several private companies to promote commercial space stations

The retirement of the International Space Station in 2030 has led NASA to refocus its efforts on continuing microgravity research through private partnerships, including the support of multiple commercial space stations' design and development.

Why extremophiles may play an important role in terraforming Mars

Possessing unique biochemicals that can detoxify extreme environments and resilience against the Martian surface that is lethal to humans, scientists are exploring whether colonies of these organisms can transform small areas of the Red Planet into future habitats for humans. Extremophiles may also be best equipped to serve as microscopic factories for the fabrication of essential polymers.

NASA explores Earth's deepest oceans to prepare for space

By studying extreme environments in Earth's hadal zone—the deepest part of the ocean —NASA tests technologies, probes life under crushing pressure, and gathers clues about potential oceans and possible life on worlds like Europa and Enceladus.

Since 2019, a free-floating robotic system named Astrobee has helped astronauts with routine tasks on the International Space Station.

Astronauts agree: The moon smells like gunpowder

Twelve astronauts have walked on the moon to date, and they all agree that our lunar neighbor smells like gunpowder. Scientists argue this scent comes from unstable minerals that cling to their suits and the rocks they return to the ship. Notwithstanding, space itself has a different smell, often compared to steak or metal, which experts believe, rather poetically, is the smell of dead stars.

Space trash forced astronauts on the International Space Station to take shelter

An inactive Russian satellite broke up into nearly 200 pieces, prompting astronauts on the space station to take shelter in a docked spacecraft and a capsule that could be used to escape in case of emergency.

The origin of cyborgs

The term "cyborg" was coined in a 1960 academic paper discussing what alterations humans would need to undergo to survive in extraterrestrial environments, a venture far "more logical than providing an earthly environment" in space. According to authors Manfred E. Clynes and Nathan S. Kline, Cyborgs with a capital C have incorporated exogenous components that extend their ability to adapt to new environments. Read the paper here.

Mixed reality technology helped make repairs to a quantum physics facility in space

In 2021, astronaut Megan McArthur used a HoloLens to work alongside Earth-based engineers and make hardware replacements to the International Space Station's Cold Atom Lab, the first quantum science facility in Earth orbit. The facility cools atoms to near absolute zero to perform quantum chemistry experiments in a microgravity environment.