As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

The applications and industrial uses of graphene, the single-atom-thick material

Shortly after its discovery in 2004, the strength, flexibility, optical properties, and conductivity of this thin layer of carbon atoms earned it the designation of a "wonder material," but breakthroughs in its use have taken decades of research. As of 2026, graphene-enhanced electronic sensors, optical microchips, concrete, and supercapacitors are available, though scale production challenges remain.

Nature simultaneously published three papers on DNA—only the first made history

Papers by Watson and Crick, Wilkins, and Franklin were fast-tracked without peer review, and their order was arranged between lab heads and editors. Franklin's appeared last, making her paper read as though supporting Watson and Crick—because they'd already incorporated her data before it was published.

Peptide research dates back to the late 1800s

Peptide science dates back to the late 1800s with some early peptide synthesis work, but peptides took off in the medical sphere after surgeon Frederick Banting and his colleague's isolation of insulin from dog pancreases in 1921.

As of 2026, the Pontifical Academy of Sciences, which advises the pope on scientific matters, has included 90 Nobel laureates among its members.

During his 'miraculous year,' Einstein published four groundbreaking papers

The 1905 "annus mirabilis" papers explained the photoelectric effect, Brownian motion, the absolutism of the speed of light, and mass-energy equivalence, revolutionizing scientists' understandings of space, time, mass, and energy. For the discovery of the photoelectric effect, Einstein won the 1921 Nobel Prize in Physics.

Browse a list of the most important scientific breakthroughs from each state

Although scientific discoveries involve experimentation, analysis, and collaborations among many individuals across a variety of locations, some observations, advancements, and breakthroughs have their origins in facilities within the US. These include the polio vaccine in Pennsylvania, the breathalyzer in Indiana, the observation of Pluto in Arizona, and the invention of nylon and Teflon in Delaware. (Some readers may experience a paywall.)

How PageRank—Google's search algorithm—mimics academic citation analysis

Just as research papers carry more weight if they are cited more often and cite major papers to reach their conclusion, Google's PageRank identifies search relevance based on the number and quality of links pointing to a page.

Scientific breakthroughs funded by NASA, the NSF, and the NIH include GPS, sign language, bladeless LASIK surgery, and quantum dots—tiny semiconductor crystals used in many modern televisions.

View a collection of historical documents about molecular biology's history

The collection features materials related to those involved in the discovery of DNA and provides historical context for the discoveries of RNA, various viruses, and important bioproteins. The items include photographs, business correspondence, manuscripts, and scientific instruments.

More than 100,000 scientific publications between 1953 and 2018 reported using HeLa cells—the cancerous cells nonconsensually taken from a Black woman named Henrietta Lacks in 1951.

Explore a list of Nobel Prize winners supported by National Science Foundation grants

As of 2025, 274 Nobel laureates have received funding from the NSF at some point during their careers, including 49 in physiology or medicine, 82 in physics, and 70 in chemistry. The 73 NSF-funded laureates in economics include every prize winner since 1997.

The secret lives of cells

Cutting-edge microscopy has revealed previously unseen interactions of biological molecules within their cellular environment, enabling scientists to observe and analyze the molecules in a holistic view. This podcast explains the minute advancements made over the last few decades in observing cells, revealing how scientists have come and what the future holds for the field.

Of the 736 Nobel Prizes in physics, chemistry, physiology or medicine, and economics awarded through 2023, more than 95% come from the same academic family, having been taught by a lineage of previous winners.

A look at the giants of quantum mechanics

German physicist Max Planck publishes his groundbreaking study of the effect of radiation on a “blackbody” substance, and the quantum theory of modern physics

The 2018 Nobel Prize in physics was awarded for creating tweezers out of light

At 96, Arthur Ashkin became the oldest person to win a Nobel Prize in Physics for demonstrating how lasers can hold and measure objects, a technique that has since been used to explore microbiological environments. The award was also given to Gérard Mourou and Donna Strickland for developing a method of creating optical pulses.

Critics say Nobel Prizes need updating to reflect how science and society work today

The rules still favor individuals over teams and may reflect outdated views on who does science. In 2013, the Nobel Prize in physics went to two theorists, even though over 5,000 scientists helped confirm the Higgs boson.

Learn the history of food science breakthroughs from the 20th century

Long after humans developed the means to produce sufficient food to feed civilizations, scientific research focused on a wide variety of objectives, such as developing methods to preserve food quality (accomplished via frozen food), speeding up cooking (leading to the microwave), and lowering the cost of sweetening food, which high fructose corn syrup provides.

The 2008 Nobel Prize in chemistry was awarded for discovering and developing uses for green fluorescent protein—a biomolecule found in Aequorea victoria, a jellyfish native to the Pacific Northwest.

Cooling silica nanoparticles lets physicists push the boundary of how large an object can still behave quantum mechanically.

See a timeline of landmark discoveries in the field of genetics to gain a better understanding of more than a century of advances.

The Nobel Prize remains science's top honor despite limits and inequities

Each October, a few scientists gain global fame when told they’ve won a Nobel Prize—a century-old award founded by Alfred Nobel to recognize major achievements. While the prizes boost attention and prestige for winners, they exclude many deserving scientists due to rigid rules.

CRISPR turns 10 years old

When Dr. Jennifer Doudna and colleagues released a paper in 2012 demonstrating the ability to harness the cell's natural immunity machinery to edit DNA, it received little fanfare. A decade later, the gene editing technology has led to innovations in medicine, evolution, and agriculture—and raised profound ethical questions about altering human DNA.

Beyond DNA, Franklin's legacy extends into modern virology and steel production

While remembered for her critical but under-credited role in uncovering parameters for the structure of DNA, Rosalind Franklin made significant contributions across coal chemistry and virus structure. Her research helped improve fuel efficiency, wartime protective equipment, and foundational knowledge in molecular biology.

Computational and biological systems share fundamental principles, like randomness

Proposed by Alan Turing and John von Neumann, the concept originates from how DNA and computers run by executing encoded instructions in parallel. The advent of AI and the temperature parameter has seen neural networks mimic the randomness of protein encoding.

View a ranking of the masses of fundamental particles, from the massless photon to the top quark, and a timeline of their discoveries.

Nanotechnology refers to the study of objects measuring 1 to 100 billionths of a meter, which has produced materials with unique properties by manipulating the arrangement of atoms.

Non-Nobel Prize awards recognize topics outside of chemistry, physics and medicine

Established in 2002, the Abel Prize awards $750,000 to a mathematician for pioneering scientific achievements, while the $1M Turing Award honors contributions in computer science. Additional prizes in earth science, engineering, environmental science and policy, astrophysics, nanoscience and neuroscience have also been established.

An overview of the National Science Foundation and the technologies it has helped fund

Established in 1950, the federal agency has provided billions of dollars to over 300,000 researchers, entrepreneurs, and students to conduct research across all seven continents. These funds have contributed to major technological achievements, from the invention of the internet to the first image of a black hole.

Anthropic's Claude Science is an AI workbench connected to more than 60 scientific databases, designed to assist scientific research in molecular and cellular biology and drug discovery.

English chemist Rosalind Franklin (1920 - 1958) on the importance of science

"Science and everyday life cannot and should not be separated. Science, for me, gives a partial explanation of life."

Rosalind Franklin’s work led to Nobel Prize-winning discoveries in DNA and virology

Her X-ray diffraction imaging helped uncover the structure of DNA, which earned James Watson, Francis Crick, and Maurice Wilkins a Nobel Prize. The same techniques enabled virus imaging, contributing to Aaron Klug's Nobel Prize in chemistry.

Using deep learning to analyze tumors

The explosive growth of life sciences data is driving artificial intelligence methods to gain traction in biology and medicine — including cancer research.

Learn why modern scientific patterns have been described as theories rather than laws

After confirming that the accuracy of some laws of physics is limited to certain domains, science became more hesitant to categorize identified mathematical relationships, such as quantum mechanics, as unchanging laws. Instead, these recent, complex frameworks are designated as theories to acknowledge that they are conditional and may be part of a larger, more complete future framework.

Lasers, semiconductors, medical imaging, and atomic clocks rely on quantum mechanics

Semiconductors, crucial in electronics, operate based on quantum superposition. Lasers use stimulated emission, a quantum process, and MRI machines leverage the quantum spin of hydrogen atoms for imaging. Atomic clocks measure time with unprecedented precision using quantum transitions.

The history of molecular gastronomy, from thickening yolks with alcohol to making art with food

Before understanding why they worked, humans used scientific principles, including designing solutions and analyzing outcomes, to develop preservation methods like curing meat and fermenting vegetables. By the 20th century, the application of industrialized food preparation to smaller kitchens set the stage for the subdiscipline of food science.

As of 2022, about 40% of scientific research aimed at generating new knowledge has been funded by the federal government—a percentage that has decreased from a high of 72% in 1967.

Glowing chemicals allow scientists to read DNA like a barcode

The process of determining the order of nitrogenous bases in DNA involves first cutting the DNA into fragments, which are duplicated multiple times using bacteria. Fluorescently labeled terminator bases are added to fragments, which are sorted by length and read via laser to reconstruct the sequence.

Advance genetic research by playing these scientific video games

Computers produce so much information that researchers can't properly analyze all the data produced, and the overload can also lead computers to make mistakes. Researchers are increasingly turning to citizen scientists—members of the public who are willing to volunteer—to help them make sense of data when computers can't. This article details a few of the ways you can contribute to genetics research by playing video games.

DNA computing allows for storage and processing of massive amounts of data

Although costly and less efficient for simpler tasks, as of 2025, DNA could hold 455 exabytes of data with near limitless parallel computation potential in small data centers. Every movie ever made would fit inside the volume of a single sugar cube.

X-rays earned the very first Nobel Prize in physics for revealing hidden worlds

In 1895, Wilhelm Conrad Röntgen discovered X-rays, which could pass through solid objects and make unseen structures visible. Today’s X-ray tools continue to advance science and medicine, including capturing real-time images of proteins.

A pediatric journal ran 138 fictional case studies, and 61 were cited as real stories

The Canadian journal Paediatrics & Child Health issued corrections to 138 case studies published since 2000, acknowledging the cases were entirely fictional—a practice intended to protect patient privacy that was never disclosed to readers. At least 61 of the fabricated reports were cited as fact in other peer-reviewed journals a combined 218 times, including a 2006 Lancet article alleging an infant died from opioid-laced breast milk.

View the most expensive materials on Earth, led by antimatter and other elements forged in particle accelerators.

In 2000, the Clay Mathematics Institute placed million-dollar bounties on seven unsolved problems in mathematics—the Millennium Prize Problems—in the hopes of spurring solutions.

View an historical mural depicting the NSF's impact across seven decades

From 1950 to 2020, the National Science Foundation supported discovery-based, exploratory research that led to numerous breakthroughs, including the development of supercomputing centers, 3D printing technologies, biometric identification systems, an understanding of vector-borne illnesses, a DNA amplification technique, mobile meteorology units, and scientific education and literacy programming.

Scientists can tag distinct proteins with fluorescent probes that emit different colors, allowing them to visualize multiple biochemical processes simultaneously.

Several birthstones play key roles across modern technologies

Diamonds are used in drills and quantum computing, while peridot and zircon help in steelmaking and carbon capture. Rubies, sapphires, and alexandrite enable several varieties of lasers found in medicine and advanced optics. Garnets are found in water filtration systems and radiation detectors. Sapphires are used as substrates in semiconductors.

One of Einstein's papers challenged quantum theory but helped confirm entanglement

In 1935, Einstein suggested that quantum mechanics was incomplete due to its strange implications about entangled particles. Their challenge led to decades of experiments that eventually proved distant particles could affect each other instantly.

Exploring carbon compound pore structures contributed to improved gas mask filtration

During World War II, the British Coal Utilisation Research Association sought to improve the efficiency of coal as an energy source and studied the effectiveness of charcoal filters to keep soldiers safe. Rosalind Franklin's research there formed the basis of her PhD and led to five scientific papers.

Ten underrated astronomy studies from 2022

The James Webb Space Telescope understandably received a lot of coverage in 2022. This astrophysicist wants to highlight ten major studies published last year you might have missed.

Peptides may have predated ribosomes—the cell's protein factory

Some scientists have hypothesized that peptides and RNA molecules may have coevolved as a single, mixed "chimeric" molecule, fueling the beginning of protein production and predating a primitive version of the ribosome. All life today uses ribosomes to make peptides. (Some users may experience a paywall.)