How the most famous Ebola book, The Hot Zone, which sold 3.5 million copies and was translated into 30 languages, got aspects of the disease so wrong.

Ebola virus, with an average fatality rate of around 50%, has been responsible for more than 2,000 confirmed deaths during the 2026 outbreak in the Democratic Republic of the Congo and Uganda.

There have been close to 40 Ebola outbreaks since 1976

Ebola is a rare but deadly virus that causes severe illness, organ damage, and sometimes internal bleeding. It spreads through contact with infected bodily fluids and is most common in parts of sub-Saharan Africa. This explainer covers its symptoms, transmission, and treatment options.

See how Ebola tore through Guinea, Sierra Leone, and Liberia in 2014-16.

Three Ebola species are responsible for most large outbreaks of the disease.

Watch what the Ebola virus does inside the body in order to spread and survive.

The 2026 Ebola outbreak is hampered by a lack of vaccine against the relevant species of the virus, heightening the need for rapid tests to aid in disease control.

Scientists have struggled to pin down Ebola's natural reservoir species for decades, but the available evidence suggests that it's very likely fruit and insect-eating bats found in Africa.

Watch how viruses like Ebola can spill over from animals to humans—and vice-versa.

See the evolution of Ebola vaccine and treatment development.

Ebola is a filovirus, meaning it resembles a thread under a microscope.

See how the Ebola virus affects blood circulation in the human body.

Ebola species have historically been named after the places where they were discovered, stigmatizing residents of those areas, including Bundibugyo, in Uganda.

Learn how monoclonal antibodies, which mimic the body's antibodies, can fight diseases like Ebola.

An Ebola vaccine was developed during the 2018 west African Ebola outbreak, but the 2026 Ebola outbreak is with a different species of the virus, not the one that the vaccine is approved to treat.

Cultural norms about how to handle the bodies of loved ones have hampered Ebola responses in West Africa.

Watch the cumbersome, but necessary, precautions healthcare workers must take to care for and protect themselves while caring for Ebola patients.

Marburg virus, related to Ebola, is also extremely deadly, and has no available vaccine.

Explore what it's like Inside a patient isolation unit.

The 2026 Ebola outbreak in the DRC is spurring new Ebola vaccine development for the Bundibugyo species.

During the COVID-19 pandemic, readers returned to Camus' 'The Plague'

The 1947 novel, about a city in Algeria that enacts a city-wide quarantine to battle a deadly outbreak, captured readers' attention in the early months of 2020. In the UK, over 2,000 copies of the book were sold in March of that year, over six times what it had sold the month before.

Vector-borne diseases kill more than 700,000 people globally each year—and are growing

The diseases with the greatest potential to spread widely aren't the ones that quickly kill human hosts. Instead, the best hosts or reservoirs for vector-borne diseases would be chronically ill over the long term, increasing the likelihood that the pathogen could be transmitted to others.

Increasing contact between humans and wild animals is driving zoonotic threats

Zoonotic diseases, which spread from animals to humans, present one of the most significant emerging threats worldwide. Scientists have identified around 200 viruses capable of infecting humans, and unfortunately, the number of such diseases are on the rise—at least 60% of all emerging infectious diseases are zoonotic in origin.

What are zoonotic diseases?

Interspecies interactions are a breeding ground for disease transmission. This basic background information on zoonotic disease from the Centers for Disease Control and Prevention (CDC) chronicles the different ways humans can get sick, identifies what groups are particularly vulnerable, and offers links to other resources.

Hundreds of vulnerable Chicago residents died in 1995 during a long-lasting heat wave

Eric Klinenberg wrote a book diving into the specifics of the heat wave. His book, detailing the stories and context fueling more than 700 deaths during just one summer week, helps readers understand how social infrastructure lapses, power outages, and ineffective heat responses led to so many deaths.

Truman Capote's 'In Cold Blood,' a pioneer of the true crime genre, isn't wholly accurate

The nonfiction novel "In Cold Blood" influenced true crime's narrative and investigative bend and was supposedly only 92% accurate. Journalist Ben Yagoda reflects on its accuracy after finding the fact-checking file for the four-part series published before the story was converted into hardback. Yagoda says the inaccuracies are "especially striking" because the story was originally published in one of the magazines credited with establishing fact-checking as a practice. (Some users may experience a paywall.)

Treating black fever can result in a complication that spreads the deadly disease

Black fever, a deadly parasitic disease second only to malaria, threatens more than 1 billion people across more than 83 countries. Also known as kala-azar or visceral leishmaniasis, the disease is caused by parasites that spread through sandfly...

Dr. William Gorgas eradicated yellow fever in Panama, crucial to canal construction

The disease was one of the factors hampering the French effort to build the canal. Gorgas' experience elsewhere in the Caribbean had taught him that good drainage and quaranting patients were essential, and he would eventually apply mosquito prevention tactics on a mass scale.

Animal-to-human pathogens constitute 75% of emerging infectious diseases

Zoonotic diseases encompass more than 200 diseases transmitted from animals to humans, wherein humans are usually accidental hosts. Ranging from rabies to HIV to monkeypox, this overview lists some of the most common viral threats.

Hit show 'The Last of Us' was based on the real-life Cordyceps fungus

Though it depicted a fictional world with a collapsed society due to a fungal pandemic, this television series (based on an earlier video game) helped raise awareness about fungal threats. It even prompted the US Centers for Disease Control and Prevention to publicly comment on it—clarifying the show’s plausibility. The mind-controlling fungal species in the show is based on a real-life Cordyceps species, a fungus that modifies its host’s behavior before killing it.

How a scientist discovered West Nile is spread by birds

Listen to Tracey McNamara, former chief pathologist at the Bronx Zoo, detailing her surprising late 1990s discovery that established West Nile virus is spread by birds. Financing animal disease surveillance studies, she says, saves human lives and surveillance gaps may fuel missed opportunities to identify dangerous diseases before they jump between species.

Hear what it's like to have malaria from a patient who suffered from the mosquito-borne disease.

One doctor argued vampires were based on a real disease

At a conference in 1985, Canadian biochemist David H. Dolphin posited that stories of vampires and werewolves had a real-world origin. He argued that porphyria could have caused sufferers to seek out blood, as well as experience light sensitivity and an aversion to garlic. More than one article in the 1990s discredited this take.

Nonfiction books have been struggling to sell in the mid-2020s

In the early 2020s, readers sought out nonfiction books to help explain prominent current events, such as the first presidency of Donald Trump and the BLM movement. That interest has since waned, as publishers note that readers have lately shown a preference for escapism and gather their information from podcasts.

Variola: the second-deadliest virus on Earth

Because it was declared eradicated in 1980, many forget smallpox is one of history's deadliest diseases—in its final century, it's estimated to have claimed 500 million lives. This 11-minute video from production studio Kurzgesagt takes a look at...

Watch an expert's take on the rare disease hantavirus—and why it's not of great concern to the general population

This rare zoonotic disease, transmitted to humans primarily through infected rodent droppings, urine, or saliva, is rarely spread between people. The disease was of particular concern in spring 2026, when an outbreak occurred on a 150-person cruise ship, prompting a flurry of action, including contact tracing for passengers in their home countries. The disease can be fatal. But early care—primarily oxygen support—can help patients survive.

Limited transparency soon after Chernobyl made it a source of conspiracy theories

Some rumors about the event became perceived as more reliable than the Soviet mass media, which had omitted key information during the early days of uncertainty. The resulting theories included CIA involvement in the disaster, three-headed birds, aliens, and a weaponized earthquake.

James Frey's 'A Million Little Pieces' was marketed as memoir but revealed as fiction

The addiction book became a huge success after being added to Oprah Winfrey's book club. After it was revealed to be fiction in 2005, Oprah invited Frey on her show and criticized him for deceiving her and his readers.

Bats have evolved to carry viruses without getting sick

Bats—the likely animal reservoir for diseases including Ebola and coronavirus—tolerate viruses without getting sick. The secret lies in evolutionary adaptations allowing bats to become the world’s only flying mammal and to thrive under immense physiological stressors.

Chimpanzees are dying from human colds

For some great apes, the threat of human-borne diseases outweighs poaching or habitat loss. This article details the danger of reverse zoonoses, which refers to diseases that spread from humans to animals.

A timeline of major pandemics from 1899–2025

Modern pandemics have been defined by the race between globalization (which increases risk) and the development of new medicines. The Great Influenza epidemic claimed some 50 million lives, and the COVID-19 pandemic killed more than 7 million. In between, diseases like Ebola, cholera, AIDS, and more have devastated communities.

Explore illustrative depictions of Chernobyl in comic books

Pieces related to the location since the nuclear disaster have told stories about radioactive vampires and monsters, accounts of bureaucratic corruption and creed, and visual retellings of experiences those in the region lived through before and after the event.

A malaria case in Maryland stumped doctors in 2023—leading to the wrong treatment and underscoring the challenge of physicians being mindful of tropical diseases in our interconnected world.

'Freakonomics' celebrated its 20th anniversary in 2025

The book 'Freakonomics' arguably changed the business landscape when it came out, and has since evolved into other forms of media and a cultural phenomenon.

Every virus is classified into 7 groups based on genetic differences

Viruses infecting humans have been named based on symptoms ("chickenpox") or the location or animal in which they were first discovered ("Bolivian Haemorrhagic Fever" and "Monkeypox"). For clarity among scientists and to reduce stigma, virologists classify the 15,000 known viruses (270 of which infect humans) by their basic genetic material.

Dan Buettner, the journalist who popularized the term blue zones, fires back at criticisms of blue zones in this 2026 letter to the editor published by STAT News.

HIV originated in Central and West Africa from a virus in chimpanzees

Researchers believe the virus crossed from chimpanzees to humans through bushmeat practices in the early 20th century, with genetic studies suggesting the most recent common ancestor of the HIV-1 M group, which is responsible for the global AIDS pandemic, emerged around 1910–1930 in Léopoldville (now Kinshasa) in the Belgian Congo.

Learn the history and science of influenza in 'This Podcast Will Kill You'

In their flu episode, cohosts Erin Welsh and Erin Allmann Updyke unpack influenza's biology, history, and impact—explaining everything from past pandemics to modern vaccines, all with their trademark mix of science and storytelling.

Zoonotic diseases: Pathogens that jump from animals to humans

Such diseases may be caused by a variety of pathogens—viruses, bacteria, fungi, or parasites—and can originate in creatures ranging from ticks and mosquitoes to pigs and bats. Because they develop in animals and are often new to human immune systems, zoonotic diseases have severe consequences for public health.

Time magazine ran a cover story titled 'The End of the World as We Know it?' in January 1999

In January 1999, Time published a dramatic Y2K cover with apocalyptic imagery and dire headlines. The portrayal likely exacerbated public fear and magnified the crisis in the popular imagination, turning a technical issue into a cultural panic.

The 1957 and 1968 influenza pandemics caused millions of deaths worldwide

The 1957 H2N2 pandemic spread from East Asia, killing more than 1M globally, while the 1968 H3N2 pandemic began in Hong Kong and caused a similar toll, with both strains rapidly moving across continents.