In the late 1800s, over 10,000 entries of the Oxford English Dictionary were written by a patient in a psychiatric hospital.

Charles Dickens legally separated from his wife, then tried to have her committed to a mental asylum.

'Mental hygiene' was the 1843 term for mental health

It was coined by American psychiatrist William Sweetzer to reference the same idea as personal hygiene. Mental hygiene, in Sweetzer's view, needed to be maintained in the same way people attend to their personal cleanliness, an idea that was supplanted by better understanding of the complexities of mental health disorder causes in the decades that followed.

Hippocratic doctors treated severe mental illness with the poisonous plant hellebore

Since symptoms like hallucinations were believed be due to an imbalance of black bile, yellow bile, blood, and phlegm, the treatment at the time was to bring those humors back into balance. That meant standard treatments could include bleeding a patient or using substances like hellebore to induce vomiting or diarrhea.

'Out in left field' is an idiom used to describe an eccentric person, and some researchers believe it likely originated at a minor league baseball park in Massachusetts that had an unusual outfield.

How a sick George Orwell finished '1984'

The writer worked on the novel while living in a remote cottage in Scotland. While he was there, he was in a boating accident that sent him overboard, eventually leading to a fatal bout of tuberculosis. Orwell finished the novel (and massive revisions) while trying to recover. He died in 1950, at 46.

The virus was officially described for the first time in 1789

Michael Underwood, an English physician and surgeon, was the first to describe the disorder, noting it caused disability in the lower extremities in children. Large-scale outbreaks of the disease were not observed until the late 19th century.

The peer support movement may date back to 18th century France

At the Bicêtre Hospital, an asylum near Paris, Jean-Baptiste Pussin (who had previously been a patient but later led the hospital administration) tried to hire as many staff as possible from among recovered patients. Chief physician Philippe Pinel found these individuals to be kinder than other staff and "averse from active cruelty" which was common at the time. This approach allowed the facility to move away from shackling patients and other violent methods.

Roger Bannister was the first person to break the 4-minute mile, a feat he accomplished while he was enrolled in medical school.

More than a third of America's incarcerated population has a mental illness.

The medical profession has a dark history of 'body snatching' for education

This term originally referred to secretly removing corpses from graves for sale—usually to medical schools where they were used for education. The practice dates back at least to the 1300s but still—much more rarely—persists today.

William HH Murray spurred American interest in rustic retreats, characterizing them as necessary respites from the country's oppressive urban centers.

JD Salinger served in World War II while working on a draft of his most famous novel, 'The Catcher in the Rye.'

Listen to how gaps in schizophrenia care helped to lead to a murder

Michael Laudor attended Yale, succumbed to schizophrenia, and killed his pregnant fiancée. The podcast, which includes a long but moving interview with Laudor's friend Jonathan Rosen, uses the tragedy to frame how America's approach to severe mental illness has fallen short.

The term schizophrenia was coined by Swiss psychiatrist Eugen Bleuler in 1908

He launched the word during a lecture at the German Psychiatric Association in Berlin. In his talk he focused on the splitting of psychic functioning as a defining feature of the disease and noted it wasn't associated with dementia or factors like early puberty onset.

English playwright Christopher Marlowe's violent and mysterious death

According to an official coroner’s report, in 1593 a heated argument over payment for supper escalated into a physical struggle, during which Marlowe wounded a man named Ingram Frizer, who then fatally stabbed Marlowe above the right eye. Though we still don't have a definitive explanation for why Marlowe was killed, the true motive continues to be debated, with suspicions surrounding the official account. Read more here.

When Dickens was 12, his father was imprisoned for debt

John Dickens was imprisoned at Marshalsea Debtors' Prison in London for failing to pay his debts. The experience forced the young Charles to leave school to help provide for his family. It also eventually informed his fiction, which often called for social reform, including the abolition of debtors' prisons.

Why one Emily Dickinson biographer believed she had epilepsy

Lyndall Gordon's "Lives Like Loaded Guns" points to a "handicap" referenced in several Dickinson poems. According to Gordon, the condition was so stigmatized during Dickinson's life that it made her reclusive. In this NPR interview, Gordon explains why she believes the theory is the best explanation for Dickinson's notorious isolation.

Oxford scientists turned Fleming’s mold discovery into medicine

In 1939, a team at Oxford—including Howard Florey, Ernst Chain, and Norman Heatley—revived Fleming’s forgotten discovery. Using makeshift equipment like bedpans and milk churns, they purified enough penicillin to prove it could treat deadly infections.

Read the original 1907 paper on the first known Alzheimer's patient, which was identified by Dr. Alois Alzheimer.

An 18th-century woman tricked doctors into believing she gave birth to rabbits.

True crime broadsides were a popular business venture in 19th-century England

Offered by traveling peddlers, these playbills described crimes and crime scenes in detail and often included speeches and confessions of the soon-to-be executed. Broadsides typically included illustrations of crime and execution scenes to drive home the details.

Deinstitutionalization in the 20th century unintentionally led to the incarceration of schizophrenia patients

Activism to shut down problematic asylums in the mid-20th century led to the community release of many patients with severe mental illnesses, including schizophrenia, but without adequate support, this deinstitutionalization in the 1960s and 1970s led to a significant increase in patients with schizophrenia ending up in prisons and homeless shelters.

Having five of nine key symptoms constitutes a major depression

Before professional standards were adopted, practitioners used varying criteria to diagnose mental health disorders. By the 1970s, more objective lists were organized, culminating in this list of polythetic criteria—a list of symptoms where no single criterion is required, but a minimum number must be present.

American medical organizations rescind recognition of diagnosis cited in police custody deaths

American medical organizations have rescinded their recognition of a syndrome whose theory stemmed from discredited research. This article explores the history and implications of "excited delirium syndrome," a medical condition that can reportedly...

Nobel Prize winner William Butler Yeats was fascinated by magic and the occult

The Irish poet and 1923 winner of the Nobel Prize for Literature laid out his beliefs in a 1901 essay, entitled "Magic," and was a member of several organizations dedicated to occult and mystical practices.

A young Jean-Michel Basquiat was fascinated by the medical reference book 'Gray's Anatomy,' which many believe was an early influence on his idiosyncratic style.

Readers thought the fictional Civil War vet George Dedlow, a character suffering from phantom limb pain in an 1866 story in The Atlantic, was real—and sent donations and stopped by the hospital to meet him.

Six of history's most unethical human experiments, from deliberate flu exposure to withholding syphilis treatment

Some of the progress made in mental health treatment, vaccines, blood transfusions, and more came about before the advent of consent and ethics committees, resulting in serious physical and psychological harm that participants in studies were not even anticipating.

Maps of murder across medieval England

These interactive maps show the sites of murders across York, Oxford, and London during the 14th Century. Explore the data by clicking site pins or experimenting with map filters, including crime scene type and murder weapon. Each pin includes a blurb on what researchers concluded about the attack, such as how a fight between the London fishmonger and skinner guilds during August 1340 ultimately left one man dead.

Robert Louis Stevenson wrote the entire first draft of 'The Strange Case of Dr. Jekyll and Mr. Hyde' in a frantic three days, only to burn it out of disgust.

Historians theorize Vincent Van Gogh suffered from Ménière's disease or epilepsy

A century after researchers suggested he suffered from epilepsy, some researchers in the 1990s began to support an alternate diagnosis: Ménière's disease, since he had suffered from severe, repeated attacks of disabling vertigo. Still, some researchers remain skeptical of the Ménière's diagnosis. One posits that Van Gogh had temporal epilepsy complicated by his absinthe consumption.

Everything you know about Phineas Gage is wrong

A stray spark sent a 3.5-foot-long, 1.25-inch thick iron rod through the brain of foreman Phineas Gage in 1848, creating a scientific case that has attracted onlookers for nearly two centuries. His life reportedly soon spiraled out of control, with his behavior tending toward selfishness and chaos. Evidence of these changes is far less common, with Gage's story bloated by fabrication, scientific prejudice, and artistic license.

In 1951, a small French town was likely overtaken by the fungus that ultimately led to LSD.

Browse a fan-made 'Newspeak Dictionary'

In Orwell's "1984," citizens of Oceania are expected to use Newspeak, a form of English that limits abstract thought and reinforces the government's version of reality. This satirical dictionary of the language demonstrates how Orwell constructed a lexicon for his fictional world.

Early English fantasy writers built on horror and Gothic texts

After the success of 19th-century books like Mary Shelley’s “Frankenstein” and Robert Louis Stevenson’s “The Strange Case of Dr. Jekyll and Mr. Hyde,” readers were eager for more stories that deviated from realism. Early 20th-century texts like George MacDonald’s “Phantastes” and Lord Dunsany’s “The King of Elfland’s Daughter” met the moment, laying the groundwork for the fantasy genre.

Wilhelm Wundt, the forgotten father of modern psychology

He was the first psychologist to call himself one, and he influenced a whole generation of early psychologists. Learn about the life and works of Wilhelm Wundt with this thorough entry from a philosophy encyclopedia.

Twain claimed to possess 'mental telegraphy'

In an 1891 essay, the writer claimed to possess psychic powers. It’s something that seemingly supported by his mother and his own death: Twain predicted he would die the day after Halley’s Comet returned in 1910, which did indeed happen.

An LSD scientist's role in a US mind control project

Within a decade of LSD's discovery, the US government had launched a secret initiative involving hypnosis and hallucinogens. LSD researcher Louis Jolyon West conducted experiments for the CIA's MKUltra project, which focused on the potential of mind control. He later took part in a criminal trial that hinged on testimony whose sourcing was seemingly inspired by MKUltra experiments. This article explores light shed by West's personal archive.

Ray Bradbury said he was inspired to pursue writing after meeting a magician named Mr. Electrico, but scholars have never been able to confirm the story.

James Garfield's 79-day decline hooked America on news updates

After he was shot while departing Washington, DC, in 1881, the president was treated for his wounds and cared for at the White House. Since 1861, telegraphs had spanned the continent, and the Associated Press pooled sources to share telegraph news. The public, seeking updates on the president's condition, was able to receive them regularly for the first time due to this network, laying the foundation for the continuous news cycle.

Read the 1866 story in The Atlantic that put phantom limbs on the map, a fictional story by a Civil War surgeon that was mistaken for being a true account by many readers.

Read an account of what life was like in America's national leprosarium—its leper colony

José Ramirez Jr. shares an account of his eight years at the 300-acre national leprosarium in Carville, Louisiana, from 1968 through the mid-1970s. Mostly staffed by nuns with nursing degrees, this facility was home to hundreds of people at a time, and it's also the site where they were required to be buried.

In 1892, two scientists purposefully infected themselves with cholera bacteria

When they became ill—one with mild diarrhea and the other with severe cholera—researchers pointed to that as proof that the pathogen caused the disease.

Play 17th-century death roulette

Before modern science and medicine, death was much harder to escape. Using real mortality records from London's Dreadful Visitation–a collection of all the Bills of Mortality from 1665–this interactive game gives you an idea of what may have possibly killed you during the Great Plague. Grow your appreciation for life today as you stumble upon causes of death like “livergrown” and “drowned at St. Katharine’s by the Tower”.

'Muggle’ entered the Oxford English Dictionary in 2003

The Harry Potter term for a nonmagical person became an official English word when the Oxford English Dictionary added it in 2003—cementing the series’ influence on modern language and popular culture.

Sir Thomas Overbury's poem "A Wife" inspired its subject to poison him

Overbury wrote the critical poem to suggest that the ex-wife of his friend Robert Carr, Frances Howard, had failed in her marital duties. Its contents enraged her, leading her to craft a conspiracy that left Overbury dead from poisoning.

See the list of alleged communists Orwell gave to the British government

In 1949, Orwell provided a list of communist sympathizers to a British anti-communist propaganda unit, naming figures like actor Charlie Chaplin and writer John Steinbeck. When it was made public in 2003, some called Orwell a government informant, though others blamed his tuberculosis, which would take his life a year later, while others blamed his romantic interest in the woman who asked him for the names.

A teenage Dickens found work as a political journalist

Dickens found work as a reporter for the Mirror of Parliament, a weekly newspaper focused on the British legislature. After a few years, he moved to the Morning Chronicle, where he began producing his creative work. Professor John Drew, author of "Dickens, the Journalist," said that the writer "realized he could wield a much more direct, if not more glamorous kind of power, by using his position as a leading writer of fiction and a magazine editor."

Scientists identify hundreds of genes responsible for OCD

Researchers analyzed the DNA of more than 53,000 people with OCD and identified 30 areas in the genome linked to the disease, containing 249 genes of interest. Of those, several were linked to other brain disorders, paving the way for genetic treatments of various mental illnesses.

An engineer tracked his moods for decades and helped researchers identify SAD

Civil engineer Herb Kern had bipolar and would record his moods dating back to 1967. He noticed the seasons were a major factor in the increase and severity of his episodes. By reaching out to researchers at the National Institute of Mental Health, Kern became the first human to confirm increased melatonin levels during winter and to receive bright light therapy.