Making industrial chemicals with synthetic biology

Synthetic biology transforms cells into custom DNA foundries

At companies like Ginkgo Bioworks, researchers are reprogramming cells to act as workshops that can create custom molecules, such as medicines and fertilizers, by stitching together DNA sequences—often in novel combinations—before inserting them into an organism's genome.

Meet six commercially available synbio products

An article exploring the science behind synbio products currently on the market, and projecting the products that can be expected over the next 10 years.

Challenges for synthetic biology

Can engineering approaches tame the complexity and unpredictability of living systems? An exploration of five challenges for the field and how they might be resolved.

Is synbio really cool, really scary, or both?

There's always been a divide between technology, the inanimate stuff that we build, and biology, the living stuff that nature builds. Synthetic biologists are trying to figure out how to close the gap by building living things.

Inside the community movement behind DIY synthetic biology

Margaret Talbot spotlights the rise of DIY biology in community labs, where amateur scientists—often outside formal institutions—create everything from insulin to prosthetic prototypes. These grassroots biohackers challenge traditional science by pursuing open, accessible innovation, raising questions about credibility, ethical oversight, and acceptance by mainstream researchers.

Synthetic biology can prevent extinction by creating create disease-resilient plants and animals

Through gene editing and the deployment of artificial cells, scientists can leverage learnings from the genetic sequencing of animals with known resistances to protect endangered species. Gene editing of certain species, such as mosquitoes, can also reduce their ability to spread diseases like malaria between humans.

Visualization of printing synthetic DNA

Ever wonder how synthetic DNA is made? Discover how GenScript uses innovative technology to synthesize precise, high-quality DNA at a larger scale than ever before.

In 2026, researchers at the University of Minnesota created the world's first synthetic cell—a cell made from non-living chemical components—that can eat, grow, divide, and compete with other cells for resources.

Why bacterial bioremediation may help counter the negative effects of past chemical solutions

Molecules such as DDT, a synthetic insecticide, and PFAS—"forever" chemicals used to make products resistant to heat, water, and grease—have historically been used across various industries but are now known to be harmful. Microbes that can convert some of these substances into nontoxic products, such as water and carbon dioxide, have already been identified, with ongoing research to find others.

View the industrial applications of extremozymes, from food safety to antibiotic production

Extremophiles possess unique enzymes and organic molecules that have enabled them to adapt to and thrive in otherwise lethal environments. Because these conditions resemble those found in various areas of manufacturing and production plants, these organisms and their macromolecules can optimize industrial processes where conventional catalysts would lose their ability to speed up reactions.

In 2025, researchers in the UK began working on developing artificial DNA

The Synthetic Human Genome Project aims to one day construct human DNA, molecule by molecule, in the hopes of creating disease-resistant cells and synthetic chromosomes for study. However, critics warn it may be misused to create enhanced or modified humans.

Despite being derived from crude oil, which itself comes from organic material, synthetic plastic isn't biodegradable because it hasn't existed long enough for microbes to have developed mechanisms to break it down.

Recombinant DNA technology turns microorganisms into protein factories

Genes for molecules such as insulin can be inserted into loops of bacterial DNA called plasmids and reinserted into bacteria. Once placed in fermentation tanks, these bacteria use the gene to produce these molecules, which are then harvested and purified for eventual use.

The risks of bioremediation, from intermediate products to ecological disruption

A step in the series of complex biochemical reactions involved in the implemented bioremediation process may produce dangerous molecules—sometimes more toxic than the initial pollutants—that require ongoing monitoring to ensure optimal conditions for processing these intermediates toward the eventual, safe outputs. Introducing non-native nutrients or species, including GMOs, may alter existing food webs and gene pools.

Genetic engineering will change everything forever

Designer babies, the end of diseases, genetically modified humans that never age. Outrageous things that used to be science fiction are suddenly becoming reality. As scientists increasingly understand how specific genes cause disease, the possibility of engineering our genes to not only "fix" problems but enhance our natural ability grows.

How chemical recycling could create 'infinite' plastic

The way we normally recycle plastics is a downward spiral of waste and degraded materials, but there is another option—turning plastic back into the oil it was made from.

How artificial photosynthesis can help make plastics and fuels using sunlight

These systems link a molecular light absorber to a catalyst that can synthesize fuels—such as ethanol—and ethylene, a precursor to plastics, in a carbon-neutral manner. Because these byproducts have greater energy concentrations than the carbohydrates produced by photosynthetic organisms, research is ongoing to engineer the necessary catalysts.

How synthetic meat is made

The future of meat is cheaper, faster, and more environmentally friendly—it will also be grown in a lab. This three-minute video breaks down how exactly lab-grown meat is made.

Scientists have created a cell from scratch—called a SpudCell—proof-of-concept work that a lab-made cell can feed, grow, and replicate like a natural cell.

The pharmaceutical industry evolved, in part, from the discovery of synthetic dyes

In 1856, a chemist accidentally discovered mauveine, the world's first synthetic dye, while trying to make quinine to treat malaria. The synthetic dyes that followed helped reveal germs under microscopes, paving the way for modern imaging techniques and breakthrough treatments, such as antibiotics.

How plastic manufacturing could be sustainable again

From polymers to nurdles, learn how plastic is created and what we can do to slow the lasting repercussions this material will have on both our planet and our lives.

The basics of synthetic meat

Lab-grown meat companies promise to remove animal slaughter from the production process. But they have run into a few road bumps along the way.

Most plastics are not biodegradable because breaking their chemical bonds requires temperatures lethal to most microbes, and these organisms have not been exposed to plastic long enough to evolve the necessary enzymes.

How to prevent a worst-case scenario with synbio

Author and entrepreneur Rob Reid reviews the risks of a world where more and more people have access to the technology needed to create a doomsday bug that could wipe out humanity.

Why don't we synthesize blood?

We're trying. Scientists are currently working on creating viable synthetic blood, an alternative to the presently relied-upon donations that manage to fall short of demand. More than half of the world's nations struggle to meet their population's need for blood. This article details current and historical efforts to develop synthetic blood, a venture that started more than 400 years ago.

Why extremophiles may play an important role in terraforming Mars

Possessing unique biochemicals that can detoxify extreme environments and resilience against the Martian surface that is lethal to humans, scientists are exploring whether colonies of these organisms can transform small areas of the Red Planet into future habitats for humans. Extremophiles may also be best equipped to serve as microscopic factories for the fabrication of essential polymers.

Biotech is trying to boost drug production efficiency—using chicken eggs

A company called Neion Bio is genetically engineering birds in a bid to produce medical compounds, a herculean task that scientists have struggled with for decades. The US FDA has approved only one chicken-derived drug in the past—an expensive treatment for a rare liver disorder. (Some users may encounter a paywall.)

Artificial photosynthesis turns CO₂ into sustainable fuel

Carbon conversion focuses on a central perplexing question: if carbon dioxide is a leading driver of climate change, and fossil fuels are made of carbon-based molecules, can we devise a way to convert CO₂ into useful alternatives efficiently? This video breaks down a potential pathway using artificial photosynthesis, which uses sunlight to convert CO₂ into fuel.

Biosignatures are the chemical fingerprints astrobiologists search for to find life

The 21st century has introduced advances making telescopes, cameras, and computers powerful enough to detect the presence of molecules associated with biological processes in distant atmospheres, expanding the search for life to include unreachable worlds.

How MIT researchers have used genetic mutations to improve photosynthesis efficiency

Recognizing that RuBisCO—a protein that binds carbon dioxide to other compounds to produce the building blocks of organic molecules—often mistakenly binds oxygen, scientists performed directed evolution experiments to modify the geometry of a bacterial version of the protein to cause it to preferentially interact with carbon dioxide over oxygen.

As of 2025, perfect synthetic replication of natural organs remains elusive

Advancements such as 3D printing muscles, performing vaginal reconstruction with colon tissue, and growing organs in a lab have shown promise, but artificial options and transplanting substitutions continue to exhibit functional and performance limitations compared to their natural equivalents.

Genetic engineering has accelerated millennia of altering various crops' genes

Although farmers have long cross-bred crops to obtain plants with specific colors, sizes, and other characteristics, these processes took significant time. Today, genetic modification in agriculture involves scientists altering an organism's DNA for various purposes, including enhancing pathogen resistance, removing allergens, and delaying spoilage.

Examining the potential of the emerging field of insect-based bioremediation

Also known as entomoremediation, the novel approach uses larvae and adult insects, including their gut microbiomes and associated enzymes, to extract or degrade pollutants. As of 2025, research has shown that black soldier flies can degrade a wide range of antibiotics, highlighting their potential for bioremediating antibiotic-contaminated organic waste.

An overview of bioremediation, which can help clean up oil spills, mining waste, and some plastics

The umbrella term refers to a variety of techniques that use organisms to remove harmful substances from an environment or break them down into nontoxic compounds. Because the availability of certain resources can limit the growth of these organisms and impair bioremediation efforts, nutrients such as fertilizers can be deployed to accelerate cleanup.

Learn how environmental conditions are optimized to increase bioremediation efficacy

Through biostimulation, Indigenous microbes are provided with moisture, nutrients, or oxygen to prevent their death and ensure optimal progression of their biochemical reactions. Bioaugmentation can introduce new microbial cultures to target specific compounds not natively found in the environment, while landfarming can spread or aerate contaminated soil to improve access to contaminants.

The new phenomenon of 15-minute lab-grown diamonds

In 2024, scientists developed a groundbreaking method to create diamonds at normal room temperature and pressure. This efficient and simple process contrasts with the traditional high-pressure, high-temperature method. While limitations still exist, such as minuscule sizes, this discovery moves us toward an exciting new era in diamond synthesis. Check out the article for further information about how diamonds are made.

Advances in agriculture are being powered by CRISPR to boost carbon capture

Researchers are using CRISPR to test thousands of plant gene edits, aiming to speed up breeding and maximize carbon retention in soil. By engineering drought tolerance, they also aim to increase crop yields and expand the environments where crops can grow.

It can take 10 to 15 years and more than $1B to develop a new antibiotic.

Why don't we just develop new antibiotics? In part, it's a complex scientific challenge, but market incentives also play a significant role. It can be time consuming, expensive, and most notably, we should use as little as possible to avoid driving further antibiotic resistance.

Learn about historical uses of bioremediation, the oldest cleanup method on Earth

Biochemical reactions that decompose complex molecules into simpler ones have occurred on Earth for as long as life has existed and have gradually transformed the planet into a celestial body that is increasingly habitable to greater biodiversity. Along the way, modern, human-made bioremediation techniques began to take shape in Santa Maria, California, in the 1960s.

Japanese scientists have developed an eco-friendly plastic that naturally dissolves in hours, leaving behind molecules containing phosphorus and nitrogen, which fertilize soil.

Superbugs could claim 1.9 million lives per year by 2050

The increased use of antibiotics combined with an aging population, is projected to result in an almost 50% increase in global deaths from antimicrobial resistance each year. At the same time, antibiotic use for livestock is expected to increase by 30% over the same time frame.

How microbes limited the damage and helped clean up the Deepwater Horizon oil spill

A bloom estimated to contain about 100 sextillion microbial cells broke down much of the 4.1 million barrels of spilled crude oil into nontoxic compounds in what was one of the most significant bioremediations of a human-made disaster. The microbes involved acted similarly to the first patented genetically modified organism in US history: an oil-eating bacterium engineered in 1971.

How the Supreme Court established biotechnology patent law with an oil-eating microbe

While working at General Electric, microbiologist Ananda Chakrabarty engineered a strain of Pseudomonas that could break down multiple types of hydrocarbons and filed a patent on the bioremediation organism. Despite challenges over whether living things could be patented, the 5-4 decision held that genetically modified organisms could be patented because they were human-made inventions.

An estimated 1% of DNA mutations in bacteria can produce more dangerous strains

Researchers have developed a technique to monitor these mutations in real time. Using this technology, scientists found that mutations occur at a steady rate, with 1% leading to potentially deadly changes.

How scientists are improving on photosynthesis

Researchers increased yield in soy plants by making them better at photosynthesis, the process that powers life. The findings hold promise for feeding a warming world.

Bioluminescence may provide a sustainable alternative to electric lighting

French start-up Glowee is experimenting with lights made from bioluminescent microorganisms in public spaces to reduce energy use. While the technology shows promise, challenges remain with brightness, maintenance, and scaling it for widespread use.

Synthetic textiles and tires account for more than 60% of ocean microplastic pollution, which enters the seas via runoff and wastewater discharge.

Biological terraforming studies have been conducted at Biosphere 2

The experiments involve populating barren hillslopes within the Landscape Evolution Observatory with microbes that react with air and rock to produce molecules needed by more complex organisms. Mosses and other simple plants can then grow in these spaces, gradually making them more hospitable to humans.

Hormone and peptide compounds imported from China soared in 2025

US customs data indicates that these imports doubled to $328M in the first three quarters of 2025, from $164M in the same period of 2024. The imports include GLPs, among other products. (Some users may experience a paywall.)

The science (and scams) behind essential oils

Essential oils are a big business, with industry estimates pegging its market size at $10B last year—a number expected to double by 2030. These distilled plant compounds have a long history of both legitimate and exaggerated uses, and many marketed oils are, as the author of this long read claims, just selling wish fulfillment. Revisit some of the history and contemporary use of essential oils with this piece.